| 中國醫藥大學 |
2015-06 |
Antiviral potential of a novel compound CW-33 against Enterovirus A71 via inhibition viral 2A protease
|
(Ching-Ying Wang);(An-Cheng Huang);侯曼貞(Hour Mann-Jen);(Su-Hua Huang);(Szu-Hao Kung);陳昭賢(Chao-Hsien Chen);(I-Chieh Chen);張永勳(Yuan Shiun Chang);連金城(Lien Jin Cherng)*;林振文(Lin Cheng Wen)* |
| 中國醫藥大學 |
2014-12-13 |
Exploring the factors associated with fails among the elderly in Taiwan
|
丁鈺龍;陳柔螢;陳奕良;林香汶(Margaret Hsiang-Wen Lin);侯曼貞(Hour Mann-Jen);丁鈺龍;林香汶(Margaret Hsiang-Wen Lin) |
| 中國醫藥大學 |
2014-12-13 |
Factor asscoiated with current health status among the elderly in Taiwan
|
陳柔營;丁鈺龍;陳奕良;林香汶(Margaret Hsiang-Wen Lin)*;侯曼貞(Hour Mann-Jen);陳柔螢;林香汶(Margaret Hsiang-Wen Lin) |
| 中國醫藥大學 |
2014-11-18 |
薰衣草及柳橙精油對於老年人憂鬱情緒的影響
|
蔡宛育;謝淑惠(Shwn-Huey Shieh);侯曼貞(Hour Mann-Jen);陳羿儒;陳信君(HSIN-CHUN CHEN)* |
| 中國醫藥大學 |
2014-11 |
MJ-66 induces malignant glioma cells G2/M phase arrest and mitotic catastrophe through regulation of cyclin B1/Cdk1 complex
|
(Wei-Ting Liu);(Ching Chen);(I-Chen Lu);郭盛助(Sheng-Chu Kuo);李國雄(Kuo-Hsiung Lee);陳泰霖;宋達樞;呂翼良;(Po-Wu Gean)*;侯曼貞(Hour Mann-Jen)* |
| 中國醫藥大學 |
2014-09 |
5-Lipoxygenase Inhibitors Attenuate TNF-α-Induced Inflammation in Human Synovial Fibroblasts
|
(Han-Ching Lin);(Tzu-Hung Lin);(Ming-Yueh Wu);(Yung-Cheng Chiu);湯智昕(Tang Chih-Hsin);侯曼貞(Hour Mann-Jen);(Houng-Chi Liou);(Huang-Ju Tu);(Rong-Sen Yang)*;(Wen-Mei Fu)* |
| 中國醫藥大學 |
2014-09 |
5-Lipoxygenase Inhibitors Attenuate TNF-α-Induced Inflammation in Human Synovial Fibroblasts
|
(Han-Ching Lin);(Tzu-Hung Lin);(Ming-Yueh Wu);(Yung-Cheng Chiu);湯智昕(Tang Chih-Hsin);侯曼貞(Hour Mann-Jen);(Houng-Chi Liou);(Huang-Ju Tu);(Rong-Sen Yang)*;(Wen-Mei Fu)* |
| 中國醫藥大學 |
2014-09 |
Aggravated DNA damage MJ-66 in comas a basis for enhanced glioma cell killing by bination with minocycline
|
侯曼貞(Hour Mann-Jen);(Wei-Ting Liu);(I-Chen Lu);郭盛助(Sheng-Chu Kuo);(Po-Wu Gean)* |
| 中國醫藥大學 |
2014-09 |
Aggravated DNA damage MJ-66 in comas a basis for enhanced glioma cell killing by bination with minocycline
|
侯曼貞(Hour Mann-Jen);(Wei-Ting Liu);(I-Chen Lu);郭盛助(Sheng-Chu Kuo);(Po-Wu Gean)* |
| 中國醫藥大學 |
2014-03 |
Cell death caused by quinazolinone HMJ-38 challenge in oral carcinoma CAL 27 cells: dissections of endoplasmic reticulum stress, mitochondrial dysfunction and tumor xenografts
|
呂啟誠(Chi-Cheng Lu);楊家欣(Yang Jai-Sing);江若華(Jo-Hua Chiang);侯曼貞(Hour Mann-Jen);(Kuei-Li Lin);(Tsung-Han Lee)*;鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2014-01 |
Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway
|
彭淑芬(Shu-Fen Peng);李昭瑩(Lee Chao-Ying);侯曼貞(Hour Mann-Jen);蔡士彰(Shih-Chang Tsai);郭代璜(DAIH-HUANG KUO);陳福安(FU-AN CHEN);謝博銓(PO-CHUEN SHIEH);楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2013-10 |
Application of proteomics to identify the target molecules involved in Lonicera japonica-induced photokilling in human lung cancer CH27 cells
|
廖容君(Jung-Chun Liao);張文德(Wen-Te Chang);藍于琁(Lan Yu Hsuan);侯曼貞(Hour Mann-Jen);李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2013-09 |
Impact of interleukin-10 gene polymorphisms on survival in patients with colorectal cancer
|
(Ting WC);陳璐敏(Lu-Min Chen);(Huang LC);侯曼貞(Hour Mann-Jen);藍于琁(Lan Yu Hsuan);李鳳琴(Hong-Zin Lee);游邦照(Bang-Jau You);張大元(Ta-Yuan Chang);鮑柏穎(Bo-Ying Bao)* |
| 中國醫藥大學 |
2013-09 |
Effect of DNA damage response by quinazolinone analogue HMJ-38 on human umbilical vein endothelial cells: Evidence for gammaH2A.X and DNA-PK-dependent pathway
|
江若華;楊家欣(Yang Jai-Sing);呂啟誠;侯曼貞(Hour Mann-Jen);劉國慶(KUO-CHING LIU);林楨智(Jen-Jyn Lin);林如華(JU-HWA, LIN);(T-H Lee)*;鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2013-07-31 |
從日本腦炎病毒非結構蛋白NS5之功能與結構分析探索病毒致病之分子機轉及其在藥物開發應用
|
林振文(Lin Cheng Wen);侯曼貞(Hour, Mann-Jen) |
| 中國醫藥大學 |
2013-06 |
Baicalein, ethyl acetate and chloroform extracts of Scutellaria baicalensis inhibit the neuraminidase activity of pandemic 2009 H1N1 and seasonal influenza A viruses
|
侯曼貞(Hour Mann-Jen);黃素華(Su-Hua Huang);張清堯(Ching-Yao Chang);林妍冠(Yen-Kuan Lin);王靜瑩(Ching-Ying Wang);張永勳(Yuan Shiun Chang);林振文(Lin Cheng Wen)* |
| 中國醫藥大學 |
2013-04 |
Development of novel dual-targeted anticancer agents: Molecular modeling, synthesis, cytotoxicity and anti-tumor mechanisms of 2-aryl-6-substituted quinazolinones
|
侯曼貞(Hour Mann-Jen)*;(KH Lee);(Chen TL);(Lee KT);(Zhao Yu);李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2013-03-24 |
The protective effect of 5-lipoxygenase inhibitor in animal models of Parkinson’s disease
|
康凱翔;侯曼貞(Hour Mann-Jen);洪詩雅(Shih-Ya Hung);劉鴻祺;劉鴻輝;符文美* |
| 中國醫藥大學 |
2012-08 |
Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents
|
(Xiao-Feng Wang);(Xing-Tao Tian);(Emika Ohkoshi);(Bingjie Qin);(Yi-Nan Liu);(Pei-Chi Wu);侯曼貞(Hour Mann-Jen);洪欣儀(Hsin-Yi Hung);(Keduo Qian);(Rong Huang);(Kenneth F. Bastow);(William P. Janzen);(Jian Jin);(Susan L. Morris-Natschke);李國雄(Kuo-Hsiung Lee);(Lan Xie)* |
| 中國醫藥大學 |
2012-07-31 |
合成2,4,6,7-substituted quinazoline derivatives做為第一型類胰島素生長因子受體抑制劑
|
侯曼貞(Hour Mann-Jen); 楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2012-07-31 |
開發脂氧脢抑制劑於治療腦中風與巴金森氏症之應用
|
劉宏輝;侯曼貞(Hour, Mann-Jen) |
| 中國醫藥大學 |
2012-05 |
Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice
|
呂?誠(Lu CC);楊家欣(Yang, Jai-Sing);江若華(Chiang JH);侯曼貞(Hour, Mann-Jen);(Kuei-Li Lin); 林楨智(Jen-Jyn Lin);黃雯雯(Wenwen Huang); (Minoru Tsuzuki);李宗翰(Tsung-Han Lee)*;鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2012-03-18 |
BHE Induces p53-dependent Trans-activation and Fas/CD95-dependent Apoptosis Pathway in HCT 116 human Colorectal Cancer Cells
|
張庭嘉(Ting-Chia Chang)*;邱宇任(Yu-Jen Chiu);賴光啟(Kuang-Chi Lai);林奎利(Kuei-Li Lin);彭淑芬(Shu-Fen Peng);侯曼貞(Hour Mann-Jen);李昭瑩(Lee Chao-Ying);金益安(Yih-An King);鍾景光(Jing-Gung Chung);黃雯雯(Wenwen Huang);楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2012-02 |
Development of a fast LC-MS/MS assay for the determination of deferiprone in human plasma and application to pharmacokinetics
|
宋達樞;謝右文(Yow-Wen Hsieh);彭慶添(Ching-Tien Peng);(Cheng-Hsiung Liu);(Tai-Lin Chen);侯曼貞(Hour Mann-Jen)* |
| 中國醫藥大學 |
2011-07-31 |
合成2,4,6,7-substituted quinazoline derivatives做為第一型類胰島素生長因子受體抑制劑
|
侯曼貞(Hour Mann-Jen); 楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2011-07-31 |
新穎抗癌藥物HMJ-30對U-2 OS骨癌細胞株抑制上皮-間質細胞轉換過程與轉移，經由抑制第一型類胰島素生長因子受體之訊息傳遞
|
楊家欣(Yang, Jai-Sing);鍾景光(Jing-Gung Chung);侯曼貞(Hour, Mann-Jen) |
| 中國醫藥大學 |
2011-06 |
The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino)quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor
|
陳冠廷(KUAN-TIN CHEN); 侯曼貞(Hour Mann-Jen); 蔡士彰(Shih-Chang Tsai); 鍾景光(Jing-Gung Chung); 郭盛助(Sheng-Chu Kuo); 呂啟誠(CHI-CHENG LU); 邱宇任(YU-JEN CHIU); 莊貽(YI-HSUAN CHUANG); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2011-03-31 |
以材料工程暨天然物萃取技術開發血管塗支架，子計畫2：利用電腦輔助藥物設計系統開發塗藥支架
|
侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2011-03 |
The synthesized novel fluorinated compound (LJJ-10) induces death receptor- and mitochondriadependent apoptotic cell death in the human osteogenic sarcoma U-2 OS cells
|
侯曼貞(Hour Mann-Jen)*; 楊家欣(Yang Jai-Sing); 陳冠霖(Tai-Lin Chen); 陳冠廷(Kuan-Tin Chen); 郭盛助(Sheng-Chu Kuo); 鍾景光(Jing-Gung Chung); 呂啟誠(Chi-Cheng Lu); 陳佳儀(Chia-Yi Chen); 莊貽媗(Yi-Hsuan Chuang) |
| 中國醫藥大學 |
2011-02 |
Novel Quinazoline HMJ-30 Induces U-2 OS Human Osteogenic Sarcoma Cell Apoptosis Through Induction of Oxidative Stress and Up-Regulation of ATM/p53 Signaling Pathway
|
邱宇任(Yu-Jen Chiu); 侯曼貞(Hour Mann-Jen); 呂啟誠(Chi-Cheng Lu); 鍾景光(Jing-Gung Chung); 郭盛助(Sheng-Chu Kuo); 黃雯雯(Wenwen Huang); 陳慧婕(Hui-Jye Chen); Yi-An Jin(金益安); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2011 |
2-(Naphthalene-1-yl)-6-pyrrolidinyl-4-quinazolinone inhibits skin cancer M21 cell proliferation through aberrant expression of microtubule and cell cycle
|
吳永昌; 侯曼貞(Hour Mann-Jen); 梁永昌; 吳吉育; 劉文治; 張育豪; 李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2010-09 |
Photodynamic activity of aloe-emodin induces resensitization of lung cancer cells to anoikis
|
李鳳琴(Hong-Zin Lee)*; 楊文惠(Yang, Wen-Hui); 侯曼貞(Hour Mann-Jen); (Chi-Yu Wu); 彭文煌(Wen-Huang Peng); 鮑柏穎(Bo-Ying Bao); (Ping-Hsiu Han); 包大靝(Da-Tian Bau)* |
| 中國醫藥大學 |
2010-07-31 |
利用同位素標記相對絕對定量蛋白質體技術探討HMJ-33衍生物抗血管新生機制
|
楊家欣(Yang Jai-Sing); 鍾景光(Jing-Gung Chung); 侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2010-05 |
MJ-29 inhibits tubulin polymerization, induces mitotic arrest and triggers apoptosis via CDK1-mediated Bcl-2 phosphorylation in human leukemia U937 cells
|
楊家欣(Yang Jai-Sing); 侯曼貞(Hour Mann-Jen); 黃雯雯(Wenwen Huang); 林奎利; 郭盛助(Sheng-Chu Kuo)*; 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2010-05 |
MJ-29 inhibits tubulin polymerization, induces mitotic arrest and triggers apoptosis via CDK1-mediated Bcl-2 phosphorylation in human leukemia U937 cells
|
楊家欣(Yang Jai-Sing); 侯曼貞(Hour Mann-Jen); 黃雯雯(Wenwen Huang); 林奎利; 郭盛助(Sheng-Chu Kuo)*; 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2009-07-31 |
利用同位素標記相對絕對定量蛋白質體技術探討6-pyrrolidinyl-4-quinazolinone衍生物對大腸直腸癌細胞之抗轉移、抗血管新生機制及衍生物對小鼠體內抗大腸直腸癌作用之評估
|
楊家欣(Yang Jai-Sing); 鍾景光(Jing-Gung Chung); 侯曼貞(Hour Mann-Jen); 賴光啟(Kuang-Chi Lai); 黃雯雯(Wenwen Huang) |
| 中國醫藥大學 |
2009-03-21 |
CHM-1 Suppresses MMP-2/9 via Inhibit PKB/Akt、NF-kB Signaling Pathways in EGF-induced metastasis of HT-29 Colorectal Cancer Cell cells.
|
李坤宏(Kun-Hong Li); 侯曼貞(Hour Mann-Jen); 郭盛助(Sheng-Chu Kuo); 賴光啟(Kuang-Chi Lai); 張琬若(Wan-Juo Chang); 邱宇任(Yu-Jen Chiu); 吳長霖(Chang-LinWu); 鍾景光(Jing-Gung Chung); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2009-03-21 |
Selective Induction of G2/M Arrest and Apoptosis in U2OS by a Potent Anticancer Agent, Nrf-2.
|
呂啟誠(Chi-Cheng Lu); 李宗翰(Tsung-Han Lee); 江若華(Jo-Hua Chiang); 郭盛助(Sheng-Chu Kuo); 侯曼貞(Hour Mann-Jen); 李坤鴻(Kun-Hong Li); 邱宇任(Yu-Jen Chiu); 鍾景光(Jing-Gung Chung); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2009-01-29 |
MJ-33 Suppresses VEGF Secretion and MMP-2/9 via Inhibit PKB/Akt、NF-kB and ERK Signaling Pathways in EGF-induced metastasis of HT-29 Colorectal Cancer Cells
|
楊家欣(Yang Jai-Sing)*; 侯曼貞(Hour Mann-Jen); 鍾景光(Jing-Gung Chung) |
| 中國醫藥大學 |
2008-11-07 |
The Assessment of supplying sterile syringes with needles to prevent the spread of AIDS by community pharmacists in Taichung County
|
郭啟文(CHI-WEN KUO); 侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2008-11 |
P38-associated pathway involvement in apoptosis induced by photodynamic therapy with Lonicera japonica in human lung squamous carcinoma CH27 cells.
|
梁永昌(Leung Wing-Cheung); 侯曼貞(Hour Mann-Jen); 張文德(Wen-Te Chang); (Y.-C. Wu); 賴妙英(Miao-Ying Lai); (M.-Y. Wang); 李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2008-10-17 |
HMJ-30 Suppresses MMP-2 Expression via Receptor Tyrosine Kinase Inhibition and PKB/Akt、NF-kB、ERK Signaling Pathways in U2OS cells
|
楊家欣(Yang Jai-Sing); 邱宇任; 陳冠廷; 侯曼貞(Hour Mann-Jen); 黃雯雯(Wenwen Huang); 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2008-10-17 |
HMJ-38 interacts with microtubule polymerization, induces G2/M arrest and apoptosis in human tongue cancer CAL27 cell line
|
呂啟誠; 楊家欣(Yang Jai-Sing); 郭盛助(Sheng-Chu Kuo); 高銘欽(Ming-Ching Kao); 侯曼貞(Hour Mann-Jen); 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2008-08 |
Synthesis of 2,3-Disubstituted 1,4-naphthoquinones as Antiplatelet Agents
|
連金城(Lien Jin Cherng)*; 吳啟瑞(Chi-Rei Wu); 侯曼貞(Hour Mann-Jen); 黃麗嬌(Li-Jiau Huang); (Tur-Fu Huang); 郭盛助(Sheng-Chu Kuo) |
| 中國醫藥大學 |
2008-07-31 |
開發具有潛能之生物活性化合物作為準新藥
|
郭盛助(Sheng-Chu Kuo); 黃麗嬌(Li-Jiau Huang); 連金城; 張誌祥(Chih-Shiang Chang); 林煇章(Hui-Chang Lin); 陳水田; 孫仲銘; 顧記華; 陳香惠; 鍾景光; 莊聲宏(Shin-Hun Juang); 侯曼貞(Hour Mann-Jen); 魏宗德(Tzong-Der Way) |
| 中國醫藥大學 |
2008-07-31 |
2-芳環羥基奎唑林類緣化合物之合成與利用蛋白質體技術分析其抗癌機制
|
侯曼貞(Hour Mann-Jen); 李鳳琴(Hong-Zin Lee) |
| 中國醫藥大學 |
2008-07-28 |
Oral Antithrombotic Profile of P886, a Novel Dual Inhibitor on Platelet and Intrinsic Coagulation Activity
|
連金城(Lien Jin Cherng); 侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2008-07-28 |
Synthesis of Phenylquinazolinones as Anticancer Agents
|
侯曼貞(Hour Mann-Jen); 郭啟文(CHI-WEN KUO); 楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2008-05-06 |
DNA microarray analysis of gene expression profiles in anti-cancer machanisms of the 6-pyrrolidinyl-2-(2-substituted phenyl)-4-quinazolinones derivative on U937 leukemia cells and study of the anticancer activity in leukemia animal model
|
楊家欣(Yang Jai-Sing); 侯曼貞(Hour Mann-Jen); 郭盛助(Sheng-Chu Kuo); 鍾景光(Jing-Gung Chung); 楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2008-05-06 |
DNA Microarray Analysis of Gene Expression Profiles in Anti-cancer Mechanisms of the 6-pyrrolidinyl-2-(2-substituted phenyl)-4- quinazolinones Derivative on U937 Leukemia Cells and Study of the Anticancer Activity in Leukemia Animal Model
|
楊家欣(Yang Jai-Sing); 侯曼貞(Hour Mann-Jen); 郭盛助(Sheng-Chu Kuo); 鍾景光(Jing-Gung Chung); 楊家欣(Yang Jai-Sing) |
