| 中國醫藥大學 |
2014-01 |
Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway
|
彭淑芬(Shu-Fen Peng);李昭瑩(Lee Chao-Ying);侯曼貞(Hour Mann-Jen);蔡士彰(Shih-Chang Tsai);郭代璜(DAIH-HUANG KUO);陳福安(FU-AN CHEN);謝博銓(PO-CHUEN SHIEH);楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2013-10 |
Application of proteomics to identify the target molecules involved in Lonicera japonica-induced photokilling in human lung cancer CH27 cells
|
廖容君(Jung-Chun Liao);張文德(Wen-Te Chang);藍于琁(Lan Yu Hsuan);侯曼貞(Hour Mann-Jen);李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2013-09 |
Impact of interleukin-10 gene polymorphisms on survival in patients with colorectal cancer
|
(Ting WC);陳璐敏(Lu-Min Chen);(Huang LC);侯曼貞(Hour Mann-Jen);藍于琁(Lan Yu Hsuan);李鳳琴(Hong-Zin Lee);游邦照(Bang-Jau You);張大元(Ta-Yuan Chang);鮑柏穎(Bo-Ying Bao)* |
| 中國醫藥大學 |
2013-09 |
Effect of DNA damage response by quinazolinone analogue HMJ-38 on human umbilical vein endothelial cells: Evidence for gammaH2A.X and DNA-PK-dependent pathway
|
江若華;楊家欣(Yang Jai-Sing);呂啟誠;侯曼貞(Hour Mann-Jen);劉國慶(KUO-CHING LIU);林楨智(Jen-Jyn Lin);林如華(JU-HWA, LIN);(T-H Lee)*;鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2013-07-31 |
從日本腦炎病毒非結構蛋白NS5之功能與結構分析探索病毒致病之分子機轉及其在藥物開發應用
|
林振文(Lin Cheng Wen);侯曼貞(Hour, Mann-Jen) |
| 中國醫藥大學 |
2013-06 |
Baicalein, ethyl acetate and chloroform extracts of Scutellaria baicalensis inhibit the neuraminidase activity of pandemic 2009 H1N1 and seasonal influenza A viruses
|
侯曼貞(Hour Mann-Jen);黃素華(Su-Hua Huang);張清堯(Ching-Yao Chang);林妍冠(Yen-Kuan Lin);王靜瑩(Ching-Ying Wang);張永勳(Yuan Shiun Chang);林振文(Lin Cheng Wen)* |
| 中國醫藥大學 |
2013-04 |
Development of novel dual-targeted anticancer agents: Molecular modeling, synthesis, cytotoxicity and anti-tumor mechanisms of 2-aryl-6-substituted quinazolinones
|
侯曼貞(Hour Mann-Jen)*;(KH Lee);(Chen TL);(Lee KT);(Zhao Yu);李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2013-03-24 |
The protective effect of 5-lipoxygenase inhibitor in animal models of Parkinson’s disease
|
康凱翔;侯曼貞(Hour Mann-Jen);洪詩雅(Shih-Ya Hung);劉鴻祺;劉鴻輝;符文美* |
| 中國醫藥大學 |
2012-08 |
Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents
|
(Xiao-Feng Wang);(Xing-Tao Tian);(Emika Ohkoshi);(Bingjie Qin);(Yi-Nan Liu);(Pei-Chi Wu);侯曼貞(Hour Mann-Jen);洪欣儀(Hsin-Yi Hung);(Keduo Qian);(Rong Huang);(Kenneth F. Bastow);(William P. Janzen);(Jian Jin);(Susan L. Morris-Natschke);李國雄(Kuo-Hsiung Lee);(Lan Xie)* |
| 中國醫藥大學 |
2012-07-31 |
合成2,4,6,7-substituted quinazoline derivatives做為第一型類胰島素生長因子受體抑制劑
|
侯曼貞(Hour Mann-Jen); 楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2012-07-31 |
開發脂氧脢抑制劑於治療腦中風與巴金森氏症之應用
|
劉宏輝;侯曼貞(Hour, Mann-Jen) |
| 中國醫藥大學 |
2012-05 |
Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice
|
呂?誠(Lu CC);楊家欣(Yang, Jai-Sing);江若華(Chiang JH);侯曼貞(Hour, Mann-Jen);(Kuei-Li Lin); 林楨智(Jen-Jyn Lin);黃雯雯(Wenwen Huang); (Minoru Tsuzuki);李宗翰(Tsung-Han Lee)*;鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2012-03-18 |
BHE Induces p53-dependent Trans-activation and Fas/CD95-dependent Apoptosis Pathway in HCT 116 human Colorectal Cancer Cells
|
張庭嘉(Ting-Chia Chang)*;邱宇任(Yu-Jen Chiu);賴光啟(Kuang-Chi Lai);林奎利(Kuei-Li Lin);彭淑芬(Shu-Fen Peng);侯曼貞(Hour Mann-Jen);李昭瑩(Lee Chao-Ying);金益安(Yih-An King);鍾景光(Jing-Gung Chung);黃雯雯(Wenwen Huang);楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2012-02 |
Development of a fast LC-MS/MS assay for the determination of deferiprone in human plasma and application to pharmacokinetics
|
宋達樞;謝右文(Yow-Wen Hsieh);彭慶添(Ching-Tien Peng);(Cheng-Hsiung Liu);(Tai-Lin Chen);侯曼貞(Hour Mann-Jen)* |
| 中國醫藥大學 |
2011-07-31 |
合成2,4,6,7-substituted quinazoline derivatives做為第一型類胰島素生長因子受體抑制劑
|
侯曼貞(Hour Mann-Jen); 楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2011-07-31 |
新穎抗癌藥物HMJ-30對U-2 OS骨癌細胞株抑制上皮-間質細胞轉換過程與轉移，經由抑制第一型類胰島素生長因子受體之訊息傳遞
|
楊家欣(Yang, Jai-Sing);鍾景光(Jing-Gung Chung);侯曼貞(Hour, Mann-Jen) |
| 中國醫藥大學 |
2011-06 |
The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino)quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor
|
陳冠廷(KUAN-TIN CHEN); 侯曼貞(Hour Mann-Jen); 蔡士彰(Shih-Chang Tsai); 鍾景光(Jing-Gung Chung); 郭盛助(Sheng-Chu Kuo); 呂啟誠(CHI-CHENG LU); 邱宇任(YU-JEN CHIU); 莊貽(YI-HSUAN CHUANG); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2011-03-31 |
以材料工程暨天然物萃取技術開發血管塗支架，子計畫2：利用電腦輔助藥物設計系統開發塗藥支架
|
侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2011-03 |
The synthesized novel fluorinated compound (LJJ-10) induces death receptor- and mitochondriadependent apoptotic cell death in the human osteogenic sarcoma U-2 OS cells
|
侯曼貞(Hour Mann-Jen)*; 楊家欣(Yang Jai-Sing); 陳冠霖(Tai-Lin Chen); 陳冠廷(Kuan-Tin Chen); 郭盛助(Sheng-Chu Kuo); 鍾景光(Jing-Gung Chung); 呂啟誠(Chi-Cheng Lu); 陳佳儀(Chia-Yi Chen); 莊貽媗(Yi-Hsuan Chuang) |
| 中國醫藥大學 |
2011-02 |
Novel Quinazoline HMJ-30 Induces U-2 OS Human Osteogenic Sarcoma Cell Apoptosis Through Induction of Oxidative Stress and Up-Regulation of ATM/p53 Signaling Pathway
|
邱宇任(Yu-Jen Chiu); 侯曼貞(Hour Mann-Jen); 呂啟誠(Chi-Cheng Lu); 鍾景光(Jing-Gung Chung); 郭盛助(Sheng-Chu Kuo); 黃雯雯(Wenwen Huang); 陳慧婕(Hui-Jye Chen); Yi-An Jin(金益安); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2011 |
2-(Naphthalene-1-yl)-6-pyrrolidinyl-4-quinazolinone inhibits skin cancer M21 cell proliferation through aberrant expression of microtubule and cell cycle
|
吳永昌; 侯曼貞(Hour Mann-Jen); 梁永昌; 吳吉育; 劉文治; 張育豪; 李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2010-09 |
Photodynamic activity of aloe-emodin induces resensitization of lung cancer cells to anoikis
|
李鳳琴(Hong-Zin Lee)*; 楊文惠(Yang, Wen-Hui); 侯曼貞(Hour Mann-Jen); (Chi-Yu Wu); 彭文煌(Wen-Huang Peng); 鮑柏穎(Bo-Ying Bao); (Ping-Hsiu Han); 包大靝(Da-Tian Bau)* |
| 中國醫藥大學 |
2010-07-31 |
利用同位素標記相對絕對定量蛋白質體技術探討HMJ-33衍生物抗血管新生機制
|
楊家欣(Yang Jai-Sing); 鍾景光(Jing-Gung Chung); 侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2010-05 |
MJ-29 inhibits tubulin polymerization, induces mitotic arrest and triggers apoptosis via CDK1-mediated Bcl-2 phosphorylation in human leukemia U937 cells
|
楊家欣(Yang Jai-Sing); 侯曼貞(Hour Mann-Jen); 黃雯雯(Wenwen Huang); 林奎利; 郭盛助(Sheng-Chu Kuo)*; 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2010-05 |
MJ-29 inhibits tubulin polymerization, induces mitotic arrest and triggers apoptosis via CDK1-mediated Bcl-2 phosphorylation in human leukemia U937 cells
|
楊家欣(Yang Jai-Sing); 侯曼貞(Hour Mann-Jen); 黃雯雯(Wenwen Huang); 林奎利; 郭盛助(Sheng-Chu Kuo)*; 鍾景光(Jing-Gung Chung)* |
