| 中國醫藥大學 |
2012-07-31 |
開發脂氧脢抑制劑於治療腦中風與巴金森氏症之應用
|
劉宏輝;侯曼貞(Hour, Mann-Jen) |
| 中國醫藥大學 |
2012-05 |
Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice
|
呂?誠(Lu CC);楊家欣(Yang, Jai-Sing);江若華(Chiang JH);侯曼貞(Hour, Mann-Jen);(Kuei-Li Lin); 林楨智(Jen-Jyn Lin);黃雯雯(Wenwen Huang); (Minoru Tsuzuki);李宗翰(Tsung-Han Lee)*;鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2012-03-18 |
BHE Induces p53-dependent Trans-activation and Fas/CD95-dependent Apoptosis Pathway in HCT 116 human Colorectal Cancer Cells
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張庭嘉(Ting-Chia Chang)*;邱宇任(Yu-Jen Chiu);賴光啟(Kuang-Chi Lai);林奎利(Kuei-Li Lin);彭淑芬(Shu-Fen Peng);侯曼貞(Hour Mann-Jen);李昭瑩(Lee Chao-Ying);金益安(Yih-An King);鍾景光(Jing-Gung Chung);黃雯雯(Wenwen Huang);楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2012-02 |
Development of a fast LC-MS/MS assay for the determination of deferiprone in human plasma and application to pharmacokinetics
|
宋達樞;謝右文(Yow-Wen Hsieh);彭慶添(Ching-Tien Peng);(Cheng-Hsiung Liu);(Tai-Lin Chen);侯曼貞(Hour Mann-Jen)* |
| 中國醫藥大學 |
2011-07-31 |
合成2,4,6,7-substituted quinazoline derivatives做為第一型類胰島素生長因子受體抑制劑
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侯曼貞(Hour Mann-Jen); 楊家欣(Yang Jai-Sing) |
| 中國醫藥大學 |
2011-07-31 |
新穎抗癌藥物HMJ-30對U-2 OS骨癌細胞株抑制上皮-間質細胞轉換過程與轉移，經由抑制第一型類胰島素生長因子受體之訊息傳遞
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楊家欣(Yang, Jai-Sing);鍾景光(Jing-Gung Chung);侯曼貞(Hour, Mann-Jen) |
| 中國醫藥大學 |
2011-06 |
The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino)quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor
|
陳冠廷(KUAN-TIN CHEN); 侯曼貞(Hour Mann-Jen); 蔡士彰(Shih-Chang Tsai); 鍾景光(Jing-Gung Chung); 郭盛助(Sheng-Chu Kuo); 呂啟誠(CHI-CHENG LU); 邱宇任(YU-JEN CHIU); 莊貽(YI-HSUAN CHUANG); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2011-03-31 |
以材料工程暨天然物萃取技術開發血管塗支架，子計畫2：利用電腦輔助藥物設計系統開發塗藥支架
|
侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2011-03 |
The synthesized novel fluorinated compound (LJJ-10) induces death receptor- and mitochondriadependent apoptotic cell death in the human osteogenic sarcoma U-2 OS cells
|
侯曼貞(Hour Mann-Jen)*; 楊家欣(Yang Jai-Sing); 陳冠霖(Tai-Lin Chen); 陳冠廷(Kuan-Tin Chen); 郭盛助(Sheng-Chu Kuo); 鍾景光(Jing-Gung Chung); 呂啟誠(Chi-Cheng Lu); 陳佳儀(Chia-Yi Chen); 莊貽媗(Yi-Hsuan Chuang) |
| 中國醫藥大學 |
2011-02 |
Novel Quinazoline HMJ-30 Induces U-2 OS Human Osteogenic Sarcoma Cell Apoptosis Through Induction of Oxidative Stress and Up-Regulation of ATM/p53 Signaling Pathway
|
邱宇任(Yu-Jen Chiu); 侯曼貞(Hour Mann-Jen); 呂啟誠(Chi-Cheng Lu); 鍾景光(Jing-Gung Chung); 郭盛助(Sheng-Chu Kuo); 黃雯雯(Wenwen Huang); 陳慧婕(Hui-Jye Chen); Yi-An Jin(金益安); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2011 |
2-(Naphthalene-1-yl)-6-pyrrolidinyl-4-quinazolinone inhibits skin cancer M21 cell proliferation through aberrant expression of microtubule and cell cycle
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吳永昌; 侯曼貞(Hour Mann-Jen); 梁永昌; 吳吉育; 劉文治; 張育豪; 李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2010-09 |
Photodynamic activity of aloe-emodin induces resensitization of lung cancer cells to anoikis
|
李鳳琴(Hong-Zin Lee)*; 楊文惠(Yang, Wen-Hui); 侯曼貞(Hour Mann-Jen); (Chi-Yu Wu); 彭文煌(Wen-Huang Peng); 鮑柏穎(Bo-Ying Bao); (Ping-Hsiu Han); 包大靝(Da-Tian Bau)* |
| 中國醫藥大學 |
2010-07-31 |
利用同位素標記相對絕對定量蛋白質體技術探討HMJ-33衍生物抗血管新生機制
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楊家欣(Yang Jai-Sing); 鍾景光(Jing-Gung Chung); 侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2010-05 |
MJ-29 inhibits tubulin polymerization, induces mitotic arrest and triggers apoptosis via CDK1-mediated Bcl-2 phosphorylation in human leukemia U937 cells
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楊家欣(Yang Jai-Sing); 侯曼貞(Hour Mann-Jen); 黃雯雯(Wenwen Huang); 林奎利; 郭盛助(Sheng-Chu Kuo)*; 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2010-05 |
MJ-29 inhibits tubulin polymerization, induces mitotic arrest and triggers apoptosis via CDK1-mediated Bcl-2 phosphorylation in human leukemia U937 cells
|
楊家欣(Yang Jai-Sing); 侯曼貞(Hour Mann-Jen); 黃雯雯(Wenwen Huang); 林奎利; 郭盛助(Sheng-Chu Kuo)*; 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2009-07-31 |
利用同位素標記相對絕對定量蛋白質體技術探討6-pyrrolidinyl-4-quinazolinone衍生物對大腸直腸癌細胞之抗轉移、抗血管新生機制及衍生物對小鼠體內抗大腸直腸癌作用之評估
|
楊家欣(Yang Jai-Sing); 鍾景光(Jing-Gung Chung); 侯曼貞(Hour Mann-Jen); 賴光啟(Kuang-Chi Lai); 黃雯雯(Wenwen Huang) |
| 中國醫藥大學 |
2009-03-21 |
CHM-1 Suppresses MMP-2/9 via Inhibit PKB/Akt、NF-kB Signaling Pathways in EGF-induced metastasis of HT-29 Colorectal Cancer Cell cells.
|
李坤宏(Kun-Hong Li); 侯曼貞(Hour Mann-Jen); 郭盛助(Sheng-Chu Kuo); 賴光啟(Kuang-Chi Lai); 張琬若(Wan-Juo Chang); 邱宇任(Yu-Jen Chiu); 吳長霖(Chang-LinWu); 鍾景光(Jing-Gung Chung); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2009-03-21 |
Selective Induction of G2/M Arrest and Apoptosis in U2OS by a Potent Anticancer Agent, Nrf-2.
|
呂啟誠(Chi-Cheng Lu); 李宗翰(Tsung-Han Lee); 江若華(Jo-Hua Chiang); 郭盛助(Sheng-Chu Kuo); 侯曼貞(Hour Mann-Jen); 李坤鴻(Kun-Hong Li); 邱宇任(Yu-Jen Chiu); 鍾景光(Jing-Gung Chung); 楊家欣(Yang Jai-Sing)* |
| 中國醫藥大學 |
2009-01-29 |
MJ-33 Suppresses VEGF Secretion and MMP-2/9 via Inhibit PKB/Akt、NF-kB and ERK Signaling Pathways in EGF-induced metastasis of HT-29 Colorectal Cancer Cells
|
楊家欣(Yang Jai-Sing)*; 侯曼貞(Hour Mann-Jen); 鍾景光(Jing-Gung Chung) |
| 中國醫藥大學 |
2008-11-07 |
The Assessment of supplying sterile syringes with needles to prevent the spread of AIDS by community pharmacists in Taichung County
|
郭啟文(CHI-WEN KUO); 侯曼貞(Hour Mann-Jen) |
| 中國醫藥大學 |
2008-11 |
P38-associated pathway involvement in apoptosis induced by photodynamic therapy with Lonicera japonica in human lung squamous carcinoma CH27 cells.
|
梁永昌(Leung Wing-Cheung); 侯曼貞(Hour Mann-Jen); 張文德(Wen-Te Chang); (Y.-C. Wu); 賴妙英(Miao-Ying Lai); (M.-Y. Wang); 李鳳琴(Hong-Zin Lee)* |
| 中國醫藥大學 |
2008-10-17 |
HMJ-30 Suppresses MMP-2 Expression via Receptor Tyrosine Kinase Inhibition and PKB/Akt、NF-kB、ERK Signaling Pathways in U2OS cells
|
楊家欣(Yang Jai-Sing); 邱宇任; 陳冠廷; 侯曼貞(Hour Mann-Jen); 黃雯雯(Wenwen Huang); 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2008-10-17 |
HMJ-38 interacts with microtubule polymerization, induces G2/M arrest and apoptosis in human tongue cancer CAL27 cell line
|
呂啟誠; 楊家欣(Yang Jai-Sing); 郭盛助(Sheng-Chu Kuo); 高銘欽(Ming-Ching Kao); 侯曼貞(Hour Mann-Jen); 鍾景光(Jing-Gung Chung)* |
| 中國醫藥大學 |
2008-08 |
Synthesis of 2,3-Disubstituted 1,4-naphthoquinones as Antiplatelet Agents
|
連金城(Lien Jin Cherng)*; 吳啟瑞(Chi-Rei Wu); 侯曼貞(Hour Mann-Jen); 黃麗嬌(Li-Jiau Huang); (Tur-Fu Huang); 郭盛助(Sheng-Chu Kuo) |
| 中國醫藥大學 |
2008-07-31 |
開發具有潛能之生物活性化合物作為準新藥
|
郭盛助(Sheng-Chu Kuo); 黃麗嬌(Li-Jiau Huang); 連金城; 張誌祥(Chih-Shiang Chang); 林煇章(Hui-Chang Lin); 陳水田; 孫仲銘; 顧記華; 陳香惠; 鍾景光; 莊聲宏(Shin-Hun Juang); 侯曼貞(Hour Mann-Jen); 魏宗德(Tzong-Der Way) |
