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Institution Date Title Author
國家衛生研究院 2022-08-09 Ketamine promotes breast tumor growth in a mouse breast tumor model involving with high expression of miR-27b-3p and EGFR Chen, LK;Shih, CH;Chen, SS;Huang, ZX;Chang, YJ;Chen, LY;Chuang, TH;Chen, KB
國家衛生研究院 2022-07-04 Virofree, an herbal medicine-based Formula, interrupts the viral infection of delta and omicron variants of SARS-CoV-2 Doan, LH;Chu, LW;Huang, ZY;Nguyen, AT;Lee, CY;Huang, CL;Chang, YF;Hsieh, WY;Nguyen, TTH;Lin, CH;Su, CL;Chuang, TH;Lai, JM;Wang, FS;Yang, CJ;Liu, HK;Ping, YH;Huang, CYF
國家衛生研究院 2022-05-02 Furin and TMPRSS2 resistant spike induces robust humoral and cellular immunity against SARS-CoV-2 lethal infection Lin, JJ;Tien, CF;Kuo, YP;Lin, EJ;Tsai, WH;Chen, MY;Tsai, PJ;Su, YW;Pathak, N;Yang, JM;Yu, CY;Chuang, ZS;Wu, HC;Tsai, WT;Dai, SS;Liao, HC;Chai, KM;Su, YS;Chuang, TH;Liu, SJ;Chen, HW;Dou, HY;Chen, FJ;Chen, CT;Liao, CL;Yu, GY
國家衛生研究院 2022-03-25 Honeysuckle (Lonicera japonica) and huangqi (Astragalus membranaceus) suppress SARS-CoV-2 entry and COVID-19 related cytokine storm in vitro Yeh, YC;Doan, LH;Huang, ZY;Chu, LW;Shi, TH;Lee, YR;Wu, CT;Lin, CH;Chiang, ST;Liu, HK;Chuang, TH;Ping, YH;Liu, HS;Huang, CYF
國家衛生研究院 2022-02-18 Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice Chang, CS;Yu, WH;Su, CC;Ruan, JW;Lin, CM;Huang, CT;Tsai, YT;Lin, IJ;Lai, CY;Chuang, TH;Lin, WJ;Tan, TH;Huang, HC;Juan, HF;Kao, CY
國家衛生研究院 2022-02-16 Recent advances in the development of toll-like receptor agonist-based vaccine adjuvants for infectious diseases Yang, JX;Tseng, JC;Yu, GY;Luo, Y;Huang, CF;Hong, YR;Chuang, TH
國家衛生研究院 2021-09-28 Sharpening up tumor microenvironment to enhance the efficacy of immune checkpoint blockade on head and neck cancer using a CpG-oligodeoxynucleotide Tseng, JC;Yang, JX;Liu, YL;Su, YW;Lee, AY;Chen, YW;Liu, KJ;Luo, Y;Hong, YR;Chuang, TH
國家衛生研究院 2021-07-11 Therapeutic development based on the immunopathogenic mechanisms of psoriasis Tseng, JC;Chang, YC;Huang, CM;Hsu, LC;Chuang, TH
國家衛生研究院 2021-06-29 Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation Lin, CC;Shen, YR;Chang, CC;Guo, XY;Young, YY;Lai, TY;Yu, IS;Lee, CY;Chuang, TH;Tsai, HY;Hsu, LC
國家衛生研究院 2021-06-10 Lactate Dehydrogenase-A (LDH-A) preserves cancer stemness and recruitment of tumor-associated macrophages to promote breast cancer progression Wang, S;Ma, L;Wang, Z;He, H;Chen, H;Duan, Z;Li, Y;Si, Q;Chuang, TH;Chen, C;Luo, Y
國家衛生研究院 2021-06 Type I interferon signaling accelerates liver regeneration by metabolic modulation in noninfectious Conditions Wu, MS;Kuo, YP;Lo, YC;Tsai, DJ;Lai, CY;Chuang, TH;Lin, SY;Tsai, WT;Chung, PJ;Yu, GY
國家衛生研究院 2021-05-31 NBM-BMX, an HDAC8 inhibitor, overcomes temozolomide resistance in glioblastoma multiforme by downregulating the beta-Cateninic-Myc/SOX2 pathway and upregulating p53-mediated MGMT inhibition Tsai, CY;Ko, HJ;Chiou, SJ;Lai, YL;Hou, CC;Javaria, T;Huang, ZY;Cheng, TS;Hsu, TI;Chuang, JY;Kwan, AL;Chuang, TH;Huang, CYF;Loh, JK;Hong, YR
國家衛生研究院 2021-05-18 Ionizing radiation induces resistant glioblastoma stem-like cells by promoting autophagy via the Wnt/beta-Catenin pathway Tsai, CY;Ko, HJ;Huang, CYF;Lin, CY;Chiou, SJ;Su, YF;Lieu, AS;Loh, JK;Kwan, AL;Chuang, TH;Hong, YR
國家衛生研究院 2021-04-29 ZNRF1 mediates epidermal growth factor receptor ubiquitination to control receptor lysosomal trafficking and degradation Shen, CH;Chou, CC;Lai, TY;Hsu, JE;Lin, YS;Liu, HY;Chen, YK;Ho, IL;Hsu, PH;Chuang, TH;Lee, CY;Hsu, LC
國家衛生研究院 2021-03-21 The phosphorylation status of drp1-ser637 by pka in mitochondrial fission modulates mitophagy via pink1/parkin to exert multipolar spindles assembly during mitosis Ko, HJ;Tsai, CY;Chiou, SJ;Lai, YL;Wang, CH;Cheng, JT;Chuang, TH;Huang, CYF;Kwan, AL;Loh, JK;Hong, YR
國家衛生研究院 2021-01-25 MicroRNA-3613-3p functions as a tumor suppressor and represents a novel therapeutic target in breast cancer Chen, C;Pan, Y;Bai, L;Chen, H;Duan, Z;Si, Q;Zhu, R;Chuang, TH;Luo, Y
國家衛生研究院 2020-12 Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1-mediated immunoescape via STING-IFN signaling and extracellular vesicles Cheng, AN;Cheng, LC;Kuo, CL;Lo, YK;Chou, HY;Chen, CH;Wang, YH;Chuang, TH;Cheng, SJ;Lee, AY
國家衛生研究院 2020-11-02 Toll-like receptor 21 of chicken and duck recognize a broad array of immunostimulatory cpg-oligodeoxynucleotide sequences Chuang, YC;Tseng, JC;Yang, JX;Liu, YL;Yeh, DW;Lai, CY;Yu, GY;Hsu, LC;Huang, CM;Chuang, TH
國家衛生研究院 2020-09-29 Production of electricity and reduction of high-fat diet-induced IL-6 by glucose fermentation of Leuconostoc mesenteroides Yang, JJ;Rahim, AR;Yang, AJ;Chuang, TH;Huang, CM
國家衛生研究院 2020-08-03 Mouse abdominal fat depots reduced by butyric acid-producing leuconostoc mesenteroides Yang, JJ;Pham, MT;Rahim, AR;Chuang, TH;Hsieh, MF;Huang, CM
國家衛生研究院 2020-05-29 Adjuvant effect of toll-like receptor 9 activation on cancer immunotherapy using checkpoint blockade Chuang, YC;Tseng, JC;Huang, LR;Huang, CM;Huang, CF;Chuang, TH
國家衛生研究院 2020-05-13 Leuconostoc mesenteroides fermentation produces butyric acid and mediates Ffar2 to regulate blood glucose and insulin in type 1 diabetic mice Traisaeng, S;Batsukh, A;Chuang, TH;Herr, DR;Huang, YF;Chimeddorj, B;Huang, CM
國家衛生研究院 2020-01-22 Skin cutibacterium acnes mediates fermentation to suppress the calcium phosphate-induced itching: A butyric acid derivative with potential for uremic pruritus Keshari, S;Wang, Y;Herr, DR;Wang, SM;Yang, WC;Chuang, TH;Chen, CL;Huang, CM
國家衛生研究院 2020-01-21 Cysteine-capped hydrogels incorporating copper as effective antimicrobial materials against methicillin-resistant staphylococcus aureus Yang, JJ;Huang, YC;Chuang, TH;Herr, DR;Hsieh, MF;Huang, CJ;Huang, CM
國家衛生研究院 2020-01-08 Epigenetic silencing of ubiquitin specific protease 4 by snail1 contributes to macrophage-dependent inflammation and therapeutic resistance in lung cancer Lai, CY;Yeh, DW;Lu, CH;Liu, YL;Chuang, YC;Ruan, JW;Kao, CY;Huang, LR;Chuang, TH
中山醫學大學 2020 Palladium-Catalyzed Stereoselective Aza-Wacker-Heck Cyclization: One-Pot Stepwise Strategy toward Tetracyclic Fused Heterocycles Tang, RS; Chen, LY; Lai, CH; Chuang, TH
國家衛生研究院 2019-12-24 ERK activation modulates cancer stemness and motility of a novel mouse oral squamous cell carcinoma cell line Chen, YL;Liu, KJ;Jang, CW;Hsu, CC;Yen, YC;Liu, YL;Chuang, TH;Wang, SH;Fu, YK;Kuo, CC;Chen, YW
國家衛生研究院 2019-10 A novel terminal uridyltransferase controls uridylation and degradation of Regnase-1 mRNA to regulate TLR4-triggered inflammation Hsu, LC;Lin, CC;Shen, YR;Chang, CC;Guo, SY;Young, YY;Chuang, TH
國家衛生研究院 2019-07-31 The IL-6/p-BTK/p-ERK signaling mediates the calcium phosphate-induced pruritus Keshari, S;Sipayung, AD;Hsieh, CC;Su, LJ;Chiang, YR;Chang, HC;Yang, WC;Chuang, TH;Chen, CL;Huang, CM
國家衛生研究院 2019-07-11 USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation[Erratum: Oncogene. 2018 Dec 6;37(49):6327-6340.] Lu, CH;Yeh, DW;Lai, CY;Liu, YL;Huang, LR;Lee, AYL;Jin, SLC;Chuang, TH
國家衛生研究院 2019-07-02 Method of stimulating TLR9-activated immune response Chuang, TH;Lai, CY
國家衛生研究院 2019-05-31 A derivative of butyric acid, the fermentation metabolite of staphylococcus epidermidis, inhibits the growth of a staphylococcus aureus strain isolated from atopic dermatitis patients Traisaeng, S;Herr, DR;Kao, HJ;Chuang, TH;Huang, CM
國家衛生研究院 2019-04-02 CpG-oligodeoxynucleotide, immunogenic composition including the same, and method of inducing immune response by the same Chuang, TH;Yeh, DW;Lai, CY;Liu, YL;Lu, CH
國家衛生研究院 2019-02-11 Targeting LIN28B reprograms tumor glucose metabolism and acidic microenvironment to suppress cancer stemness and metastasis Chen, C;Bai, L;Cao, F;Wang, S;He, H;Song, M;Chen, H;Liu, Y;Guo, J;Si, Q;Pan, Y;Zhu, R;Chuang, TH;Xiang, R;Luo, Y
國家衛生研究院 2019-02 Immunostimulatory activities of CpG-Oligodeoxynucleotides in teleosts: Toll-like receptors 9 and 21 Lai, CY;Yu, GY;Luo, YP;Xiang, R;Chuang, TH
國家衛生研究院 2018-12-16 Involvement of M1 macrophage polarization in endosomal Toll-Like receptors activated psoriatic inflammation Lu, CH;Lai, CY;Yeh, DW;Liu, YL;Su, YW;Hsu, LC;Chang, CH;Jin, SLC;Chuang, TH
國家衛生研究院 2018-12 A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment Liu, YT;Tseng, TC;Soong, RS;Peng, CY;Cheng, YH;Huang, SF;Chuang, TH;Kao, JH;Huang, LR
國家衛生研究院 2018-12 Establishment and characterization of novel syngeneic oral squamous cell carcinoma mouse cell lines Chen, YW;Chuang, TH;Liu, KJ;Yen, YC;Wang, SH;Kuo, CC
國家衛生研究院 2018-12 DUB3 regulated tumor associated inflammation and stemness in lung cancer cells Lu, CH;Lai, CY;Yeh, DW;Liu, YL;Chuang, TH
國家衛生研究院 2018-12 Ubiquitin specific protease 4 regulates lung cancer progression by control of inflammation and stemness Lai, CY;Yeh, DW;Lu, CH;Liu, YL;Chuang, TH
國家衛生研究院 2018-11 Synergistic effect of phosphodiesterase 4 inhibitor and serum on migration of endotoxin-stimulated macrophages Yang, JX;Hsiung, TC;Weng, FC;Ding, SL;Wu, CP;Conti, M;Chuang, TH;Catherine Jin, SL
國家衛生研究院 2018-09-20 PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency Chen, MY;Hsu, WC;Hsu, SC;Yang, YS;Chuang, TH;Lin, WJ;Tan, TH;Su, YW
國家衛生研究院 2018-08-07 Blimp-1-mediated pathway promotes type I IFN production in plasmacytoid dendritic cells by targeting to interleukin-1 receptor-associated kinase M Ko, YA;Chan, YH;Liu, CH;Liang, JJ;Chuang, TH;Hsueh, YP;Lin, YL;Lin, KI
國家衛生研究院 2018-07-23 USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation Lu, CH;Yeh, DW;Lai, CY;Liu, YL;Huang, LR;Lee, AY;Jin, SC;Chuang, TH
國家衛生研究院 2018-04-18 Establishment of a mouse model for the complete mosquito-mediated transmission cycle of Zika virus Kuo, YP;Tsai, KN;Luo, YC;Chung, PJ;Su, YW;Teng, Y;Wu, MS;Lin, YF;Lai, CY;Chuang, TH;Dai, SS;Tseng, FC;Hsieh, CH;Tsai, DJ;Tsai, WT;Chen, CH;Yu, GY
國家衛生研究院 2017-12-11 CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses Yeh, DW;Lai, CY;Liu, YL;Lu, CH;Tseng, PH;Yuh, CH;Yu, GY;Liu, SJ;Leng, CH;Chuang, TH
國家衛生研究院 2017-08-13 Natural modulators of endosomal toll-like receptor-mediated psoriatic skin inflammation Lai, CY;Su, YW;Lin, KI;Hsu, LC;Chuang, TH
國家衛生研究院 2017-05-11 Glycolysis regulates the expansion of myeloid-derived suppressor cells in tumor-bearing hosts through prevention of ROS-mediated apoptosis Jian, SL;Chen, WW;Su, YC;Su, YW;Chuang, TH;Hsu, SC;Huang, LR
國家衛生研究院 2017-04-06 Phosphodiesterase 4B negatively regulates endotoxin-activated interleukin-1 receptor antagonist responses in macrophages Yang, JX;Hsieh, KC;Chen, YL;Lee, CK;Conti, M;Chuang, TH;Wu, CP;Catherine Jin, SL
國家衛生研究院 2016-12-27 Interplay between inflammation and stemness in cancer cells: The role of toll-like receptor signaling Yeh, DW;Huang, LR;Chen, YW;Huang, CYF;Chuang, TH

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