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机构 日期 题名 作者
國家衛生研究院 2024-07-19 PTEN acts as a crucial inflammatory checkpoint controlling TLR9/IL-6 axis in B cells Tsai, PJ;Chen, MY;Hsu, WC;Lin, SF;Chan, PC;Chen, HH;Kao, CY;Lin, WJ;Chuang, TH;Yu, GY;Su, YW
國家衛生研究院 2024-06-17 Tumor promoting effect of PDLIM2 downregulation involves mitochondrial ROS, oncometabolite accumulations and HIF-1alpha activation Yang, JX;Chuang, YC;Tseng, JC;Liu, YL;Lai, CY;Lee, AYL;Huang, CYF;Hong, YR;Chuang, TH
國家衛生研究院 2024-06-06 Adaptation of a eukaryote-like ProRS to a prokaryote-like tRNApro Ivanesthi, IR;Latifah, E;Amrullah, LF;Tseng, YK;Chuang, TH;Pan, HC;Yang, CS;Liu, SY;Wang, CC
國家衛生研究院 2024-03-07 Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer Ma, L;Chen, C;Zhao, CX;Li, T;Ma, LY;Jiang, JY;Duan, ZJ;Si, Q;Chuang, TH;Xiang, R;Luo, YP
國家衛生研究院 2023-08-09 Sequence-specific targeting of C. elegans C-Ala to the D-loop of tRNA(Ala) Antika, TR;Nazilah, KR;Chrestella, DJ;Wang, TL;Tseng, YK;Wang, SC;Hsu, HL;Wang, SW;Chuang, TH;Pan, HC;Horng, JC;Wang, CC
國家衛生研究院 2023-05-29 TLR9 and STING agonists cooperatively boost the immune response to SARS-CoV-2 RBD vaccine through an increased germinal center B cell response and reshaped T helper responses Yang, JX;Tseng, JC;Tien, CF;Lee, CY;Liu, YL;Lin, JJ;Tsai, PJ;Liao, HC;Liu, SJ;Su, YW;Hsu, LC;Chen, JK;Huang, MH;Yu, GY;Chuang, TH
國家衛生研究院 2023-05-11 Induction of immune responses and phosphatidylserine exposure by TLR9 activation results in a cooperative antitumor effect with a phosphatidylserine-targeting prodrug Tseng, JC;Yang, JX;Lee, CY;Lo, CF;Liu, YL;Zhang, MM;Huang, LR;Liu, KJ;Wang, CC;Huang, CYF;Hong, YR;Tsou, LK;Chuang, TH
國家衛生研究院 2023-05-09 The Src-ZNRF1 axis controls TLR3 trafficking and interferon responses to limit lung barrier damage Lin, YS;Chang, YC;Chao, TL;Tsai, YM;Jhuang, SJ;Ho, YH;Lai, TY;Liu, YL;Chen, CY;Tsai, CY;Hsueh, YP;Chang, SY;Chuang, TH;Lee, CY;Hsu, LC
國家衛生研究院 2023-05-03 GSKIP modulates cell aggregation through EMT/MET signaling rather than differentiation in SH-SY5Y human neuroblastoma cells Tsai, CY;Ko, HJ;Chiou, SJ;Lin, XY;Chuang, TH;Cheng, JT;Su, YF;Loh, JK;Hong, YR
國家衛生研究院 2022-11-21 Formulation of SARS-CoV-2 spike protein with CpG oligodeoxynucleotides and squalene nanoparticles modulates immunological aspects following intranasal delivery Ho, HM;Huang, CY;Yang, CH;Liu, SJ;Chen, HW;Yu, GY;Chen, JK;Chuang, TH;Huang, MH
國家衛生研究院 2022-08-09 Ketamine promotes breast tumor growth in a mouse breast tumor model involving with high expression of miR-27b-3p and EGFR Chen, LK;Shih, CH;Chen, SS;Huang, ZX;Chang, YJ;Chen, LY;Chuang, TH;Chen, KB
國家衛生研究院 2022-07-04 Virofree, an herbal medicine-based Formula, interrupts the viral infection of delta and omicron variants of SARS-CoV-2 Doan, LH;Chu, LW;Huang, ZY;Nguyen, AT;Lee, CY;Huang, CL;Chang, YF;Hsieh, WY;Nguyen, TTH;Lin, CH;Su, CL;Chuang, TH;Lai, JM;Wang, FS;Yang, CJ;Liu, HK;Ping, YH;Huang, CYF
國家衛生研究院 2022-05-02 Furin and TMPRSS2 resistant spike induces robust humoral and cellular immunity against SARS-CoV-2 lethal infection Lin, JJ;Tien, CF;Kuo, YP;Lin, EJ;Tsai, WH;Chen, MY;Tsai, PJ;Su, YW;Pathak, N;Yang, JM;Yu, CY;Chuang, ZS;Wu, HC;Tsai, WT;Dai, SS;Liao, HC;Chai, KM;Su, YS;Chuang, TH;Liu, SJ;Chen, HW;Dou, HY;Chen, FJ;Chen, CT;Liao, CL;Yu, GY
國家衛生研究院 2022-03-25 Honeysuckle (Lonicera japonica) and huangqi (Astragalus membranaceus) suppress SARS-CoV-2 entry and COVID-19 related cytokine storm in vitro Yeh, YC;Doan, LH;Huang, ZY;Chu, LW;Shi, TH;Lee, YR;Wu, CT;Lin, CH;Chiang, ST;Liu, HK;Chuang, TH;Ping, YH;Liu, HS;Huang, CYF
國家衛生研究院 2022-02-18 Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice Chang, CS;Yu, WH;Su, CC;Ruan, JW;Lin, CM;Huang, CT;Tsai, YT;Lin, IJ;Lai, CY;Chuang, TH;Lin, WJ;Tan, TH;Huang, HC;Juan, HF;Kao, CY
國家衛生研究院 2022-02-16 Recent advances in the development of toll-like receptor agonist-based vaccine adjuvants for infectious diseases Yang, JX;Tseng, JC;Yu, GY;Luo, Y;Huang, CF;Hong, YR;Chuang, TH
國家衛生研究院 2021-09-28 Sharpening up tumor microenvironment to enhance the efficacy of immune checkpoint blockade on head and neck cancer using a CpG-oligodeoxynucleotide Tseng, JC;Yang, JX;Liu, YL;Su, YW;Lee, AY;Chen, YW;Liu, KJ;Luo, Y;Hong, YR;Chuang, TH
國家衛生研究院 2021-07-11 Therapeutic development based on the immunopathogenic mechanisms of psoriasis Tseng, JC;Chang, YC;Huang, CM;Hsu, LC;Chuang, TH
國家衛生研究院 2021-06-29 Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation Lin, CC;Shen, YR;Chang, CC;Guo, XY;Young, YY;Lai, TY;Yu, IS;Lee, CY;Chuang, TH;Tsai, HY;Hsu, LC
國家衛生研究院 2021-06-10 Lactate Dehydrogenase-A (LDH-A) preserves cancer stemness and recruitment of tumor-associated macrophages to promote breast cancer progression Wang, S;Ma, L;Wang, Z;He, H;Chen, H;Duan, Z;Li, Y;Si, Q;Chuang, TH;Chen, C;Luo, Y
國家衛生研究院 2021-06 Type I interferon signaling accelerates liver regeneration by metabolic modulation in noninfectious Conditions Wu, MS;Kuo, YP;Lo, YC;Tsai, DJ;Lai, CY;Chuang, TH;Lin, SY;Tsai, WT;Chung, PJ;Yu, GY
國家衛生研究院 2021-05-31 NBM-BMX, an HDAC8 inhibitor, overcomes temozolomide resistance in glioblastoma multiforme by downregulating the beta-Cateninic-Myc/SOX2 pathway and upregulating p53-mediated MGMT inhibition Tsai, CY;Ko, HJ;Chiou, SJ;Lai, YL;Hou, CC;Javaria, T;Huang, ZY;Cheng, TS;Hsu, TI;Chuang, JY;Kwan, AL;Chuang, TH;Huang, CYF;Loh, JK;Hong, YR
國家衛生研究院 2021-05-18 Ionizing radiation induces resistant glioblastoma stem-like cells by promoting autophagy via the Wnt/beta-Catenin pathway Tsai, CY;Ko, HJ;Huang, CYF;Lin, CY;Chiou, SJ;Su, YF;Lieu, AS;Loh, JK;Kwan, AL;Chuang, TH;Hong, YR
國家衛生研究院 2021-04-29 ZNRF1 mediates epidermal growth factor receptor ubiquitination to control receptor lysosomal trafficking and degradation Shen, CH;Chou, CC;Lai, TY;Hsu, JE;Lin, YS;Liu, HY;Chen, YK;Ho, IL;Hsu, PH;Chuang, TH;Lee, CY;Hsu, LC
國家衛生研究院 2021-03-21 The phosphorylation status of drp1-ser637 by pka in mitochondrial fission modulates mitophagy via pink1/parkin to exert multipolar spindles assembly during mitosis Ko, HJ;Tsai, CY;Chiou, SJ;Lai, YL;Wang, CH;Cheng, JT;Chuang, TH;Huang, CYF;Kwan, AL;Loh, JK;Hong, YR
國家衛生研究院 2021-01-25 MicroRNA-3613-3p functions as a tumor suppressor and represents a novel therapeutic target in breast cancer Chen, C;Pan, Y;Bai, L;Chen, H;Duan, Z;Si, Q;Zhu, R;Chuang, TH;Luo, Y
國家衛生研究院 2020-12 Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1-mediated immunoescape via STING-IFN signaling and extracellular vesicles Cheng, AN;Cheng, LC;Kuo, CL;Lo, YK;Chou, HY;Chen, CH;Wang, YH;Chuang, TH;Cheng, SJ;Lee, AY
國家衛生研究院 2020-11-02 Toll-like receptor 21 of chicken and duck recognize a broad array of immunostimulatory cpg-oligodeoxynucleotide sequences Chuang, YC;Tseng, JC;Yang, JX;Liu, YL;Yeh, DW;Lai, CY;Yu, GY;Hsu, LC;Huang, CM;Chuang, TH
國家衛生研究院 2020-09-29 Production of electricity and reduction of high-fat diet-induced IL-6 by glucose fermentation of Leuconostoc mesenteroides Yang, JJ;Rahim, AR;Yang, AJ;Chuang, TH;Huang, CM
國家衛生研究院 2020-08-03 Mouse abdominal fat depots reduced by butyric acid-producing leuconostoc mesenteroides Yang, JJ;Pham, MT;Rahim, AR;Chuang, TH;Hsieh, MF;Huang, CM
國家衛生研究院 2020-05-29 Adjuvant effect of toll-like receptor 9 activation on cancer immunotherapy using checkpoint blockade Chuang, YC;Tseng, JC;Huang, LR;Huang, CM;Huang, CF;Chuang, TH
國家衛生研究院 2020-05-13 Leuconostoc mesenteroides fermentation produces butyric acid and mediates Ffar2 to regulate blood glucose and insulin in type 1 diabetic mice Traisaeng, S;Batsukh, A;Chuang, TH;Herr, DR;Huang, YF;Chimeddorj, B;Huang, CM
國家衛生研究院 2020-01-22 Skin cutibacterium acnes mediates fermentation to suppress the calcium phosphate-induced itching: A butyric acid derivative with potential for uremic pruritus Keshari, S;Wang, Y;Herr, DR;Wang, SM;Yang, WC;Chuang, TH;Chen, CL;Huang, CM
國家衛生研究院 2020-01-21 Cysteine-capped hydrogels incorporating copper as effective antimicrobial materials against methicillin-resistant staphylococcus aureus Yang, JJ;Huang, YC;Chuang, TH;Herr, DR;Hsieh, MF;Huang, CJ;Huang, CM
國家衛生研究院 2020-01-08 Epigenetic silencing of ubiquitin specific protease 4 by snail1 contributes to macrophage-dependent inflammation and therapeutic resistance in lung cancer Lai, CY;Yeh, DW;Lu, CH;Liu, YL;Chuang, YC;Ruan, JW;Kao, CY;Huang, LR;Chuang, TH
中山醫學大學 2020 Palladium-Catalyzed Stereoselective Aza-Wacker-Heck Cyclization: One-Pot Stepwise Strategy toward Tetracyclic Fused Heterocycles Tang, RS; Chen, LY; Lai, CH; Chuang, TH
國家衛生研究院 2019-12-24 ERK activation modulates cancer stemness and motility of a novel mouse oral squamous cell carcinoma cell line Chen, YL;Liu, KJ;Jang, CW;Hsu, CC;Yen, YC;Liu, YL;Chuang, TH;Wang, SH;Fu, YK;Kuo, CC;Chen, YW
國家衛生研究院 2019-10 A novel terminal uridyltransferase controls uridylation and degradation of Regnase-1 mRNA to regulate TLR4-triggered inflammation Hsu, LC;Lin, CC;Shen, YR;Chang, CC;Guo, SY;Young, YY;Chuang, TH
國家衛生研究院 2019-07-31 The IL-6/p-BTK/p-ERK signaling mediates the calcium phosphate-induced pruritus Keshari, S;Sipayung, AD;Hsieh, CC;Su, LJ;Chiang, YR;Chang, HC;Yang, WC;Chuang, TH;Chen, CL;Huang, CM
國家衛生研究院 2019-07-11 USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation[Erratum: Oncogene. 2018 Dec 6;37(49):6327-6340.] Lu, CH;Yeh, DW;Lai, CY;Liu, YL;Huang, LR;Lee, AYL;Jin, SLC;Chuang, TH
國家衛生研究院 2019-05-31 A derivative of butyric acid, the fermentation metabolite of staphylococcus epidermidis, inhibits the growth of a staphylococcus aureus strain isolated from atopic dermatitis patients Traisaeng, S;Herr, DR;Kao, HJ;Chuang, TH;Huang, CM
國家衛生研究院 2019-02-11 Targeting LIN28B reprograms tumor glucose metabolism and acidic microenvironment to suppress cancer stemness and metastasis Chen, C;Bai, L;Cao, F;Wang, S;He, H;Song, M;Chen, H;Liu, Y;Guo, J;Si, Q;Pan, Y;Zhu, R;Chuang, TH;Xiang, R;Luo, Y
國家衛生研究院 2019-02 Immunostimulatory activities of CpG-Oligodeoxynucleotides in teleosts: Toll-like receptors 9 and 21 Lai, CY;Yu, GY;Luo, YP;Xiang, R;Chuang, TH
國家衛生研究院 2018-12-16 Involvement of M1 macrophage polarization in endosomal Toll-Like receptors activated psoriatic inflammation Lu, CH;Lai, CY;Yeh, DW;Liu, YL;Su, YW;Hsu, LC;Chang, CH;Jin, SLC;Chuang, TH
國家衛生研究院 2018-12 A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment Liu, YT;Tseng, TC;Soong, RS;Peng, CY;Cheng, YH;Huang, SF;Chuang, TH;Kao, JH;Huang, LR
國家衛生研究院 2018-12 Establishment and characterization of novel syngeneic oral squamous cell carcinoma mouse cell lines Chen, YW;Chuang, TH;Liu, KJ;Yen, YC;Wang, SH;Kuo, CC
國家衛生研究院 2018-12 DUB3 regulated tumor associated inflammation and stemness in lung cancer cells Lu, CH;Lai, CY;Yeh, DW;Liu, YL;Chuang, TH
國家衛生研究院 2018-12 Ubiquitin specific protease 4 regulates lung cancer progression by control of inflammation and stemness Lai, CY;Yeh, DW;Lu, CH;Liu, YL;Chuang, TH
國家衛生研究院 2018-11 Synergistic effect of phosphodiesterase 4 inhibitor and serum on migration of endotoxin-stimulated macrophages Yang, JX;Hsiung, TC;Weng, FC;Ding, SL;Wu, CP;Conti, M;Chuang, TH;Catherine Jin, SL
國家衛生研究院 2018-09-20 PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency Chen, MY;Hsu, WC;Hsu, SC;Yang, YS;Chuang, TH;Lin, WJ;Tan, TH;Su, YW

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