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| 國家衛生研究院 |
2023-02-07 |
Development of furanopyrimidine-based orally active third- generation EGFR inhibitors for the treatment of non-small cell lung cancer
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Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP |
| 國家衛生研究院 |
2022-02-07 |
Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer
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Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP |
| 國家衛生研究院 |
2022-02 |
What can the anti-apoptotic molecule, BIRC5/Survivin, do in the autophagic world?
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Cheung, CH;Lin, TY;Sarvagalla, S;Coumar, MS;Cheng, SM;Leung, E |
| 國家衛生研究院 |
2021-02-22 |
Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design
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Chandar Charles, MR;Li, MC;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2021-02-18 |
Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors
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Reddy, JS;Chen, CM;Coumar, MS;Sun, HY;Sun, N;Hsieh, HP |
| 國家衛生研究院 |
2020-08 |
The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells
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Chang, YC;Kondapuram, SK;Yang, TH;Syed, SB;Cheng, SM;Lin, TY;Lin, YC;Coumar, MS;Chang, JY;Leung, E;Cheung, CHA |
| 國家衛生研究院 |
2020-07-07 |
Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors
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Syed, SB;Lin, SY;Arya, H;Fu, IH;Yeh, TK;Charles, MRC;Periyasamy, L;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2020-05 |
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors
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Lin, SY;Chang, CF;Coumar, MS;Chen, PY;Kuo, FM;Chen, CH;Li, MC;Lin, WH;Kuo, PC;Wang, SY;Li, AS;Lin, CY;Yang, CM;Yeh, TK;Song, JS;Hsu, JTA;Hsieh, HP |
| 國家衛生研究院 |
2020-01 |
Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening
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Chandar Charles, MR;Mahesh, A;Lin, SY;Hsieh, HP;Dhayalan, A;Coumar, MS |
| 國家衛生研究院 |
2019-10-15 |
BIRC5/Survivin is a novel ATG12?ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells
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Lin, TY;Chan, HH;Chen, SH;Sarvagalla, S;Chen, PS;Coumar, MS;Cheng, SM;Chang, YC;Lin, CH;Leung, E;Cheung, CHA |
| 國家衛生研究院 |
2019-10-15 |
BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells
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Lin, TY;Chan, HH;Chen, SH;Sarvagalla, S;Chen, PS;Coumar, MS;Cheng, SM;Chang, YC;Lin, CH;Leung, E;Cheung, CHA |
| 國家衛生研究院 |
2019-09 |
Design of a potent anticancer lead inspired by natural products from traditional Indian medicine
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Arya, H;Yadav, CS;Lin, SY;Syed, SB;Charles, MRC;Kannadasan, S;Hsieh, HP;Singh, SS;Gajurel, PR;Coumar, MS |
| 國家衛生研究院 |
2019-05-29 |
Insights for the design of protein lysine methyltransferase G9a inhibitors
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Charles, MRC;Dhayalan, A;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2018-07-26 |
Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study
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M, RCC;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2017-08-11 |
Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer
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Syed, SB;Arya, H;Fu, IH;Yeh, TK;Periyasamy, L;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2017-07 |
Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors
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Singh, VK;Chang, HH;Kuo, CC;Shiao, HY;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2016-07 |
Therapeutic polymeric nanoparticles and the methods of making and using thereof: A patent evaluation of WO2015036792
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Sarvagalla, S;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2016-03 |
Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and in vitro testing for the anti-cancer drug target survivin
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Sarvagalla, S;Cheung, CHA;Tsai, JY;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2015-07-31 |
作為極光激酶抑制劑的稠合雙環嘧啶化合物
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Hsieh, HP;Coumar, MS;Wu, SY;Hsu, TA;Chao, YS |
| 國家衛生研究院 |
2015-07-22 |
作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物
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Hsieh, HP;Coumar, MS;Hsu, TA;Lin, WH;Chen, YR;Chao, YS |
| 國家衛生研究院 |
2015-06-29 |
Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification
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Ke, YY;Singh, VK;Coumar, MS;Hsu, YC;Wang, WC;Song, JS;Chen, CH;Lin, WH;Wu, SH;Hsu, JT;Shih, C;Hsieh, HP |
| 國家衛生研究院 |
2015-04-14 |
Fused multicyclic compounds as protein kinase inhibitors
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Hsieh, HP;Coumar, MS;Chao, YS |
| 國家衛生研究院 |
2015-01 |
Identification of ligand efficient, fragment-like hits from an HTS library: Structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity
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Sarvagalla, S;Singh, VK;Ke, YY;Shiao, HY;Lin, WH;Hsieh, HP;Hsu, JTA;Coumar, MS |
| 國家衛生研究院 |
2014-10-29 |
作為極光激酶抑制劑的稠合雙環嘧啶化合物
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Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS |
| 國家衛生研究院 |
2014-08 |
Ligand efficiency based approach for efficient virtual screening of compound libraries
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Ke, YY;Coumar, MS;Shiao, HY;Wang, WC;Chen, CW;Song, JS;Chen, CH;Lin, WH;Wu, SH;Hsu, JT;Chang, CM;Hsieh, HP |
Showing items 1-25 of 66 (3 Page(s) Totally)
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