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Showing items 26-75 of 86 (2 Page(s) Totally)
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| 國家衛生研究院 |
2017-03-21 |
Pyrrolidine derivatives
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Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2016-12 |
Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST
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Shiao, HY;Tsai, HJ;Lin, WH;Tsu, TA;Yeh, TK;Chen, CT;Jiaang, WT |
| 國家衛生研究院 |
2016-10 |
BPR1J373, an oral multiple tyrosine kinase inhibitor, targets c-KIT for the treatment of c-KIT driven myeloid leukemia
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Chen, LT;Chen, CT;Jiaang, WT;Chen, TY;Butterfield, JH;Shih, NY;Hsu, JT;Lin, HY;Lin, SF;Tsai, HJ |
| 國家衛生研究院 |
2016-08-30 |
Pyrrolidine derivatives
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Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2016-04-12 |
Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK)
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Tu, CH;Lin, WH;Peng, YH;Hsu, T;Wu, JS;Chang, CY;Lu, CT;Lyu, PC;Shih, C;Jiaang, WT;Wu, SY |
| 國家衛生研究院 |
2016-02-09 |
Pyrazole compounds and thiazole compounds as protein kinases inhibitors
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Jiaang, WT;Hsu, TA;Lin, WH;Chao, YS |
| 國家衛生研究院 |
2015-11-13 |
Pyrrolidine derivatives
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Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2015-07 |
Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations
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Chen, CT;Hsu, JTA;Lin, WH;Lu, CT;Yen, SC;Hsu, T;Huang, YL;Song, JS;Chen, CH;Chou, LH;Yen, KJ;Chen, CP;Kuo, PC;Huang, CL;Eugene Liu, H;Chao, YS;Yeh, TK;Jiaang, WT |
| 國家衛生研究院 |
2014-08-01 |
Pyrrolidine derivatives
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Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2014-05-12 |
Pyrrolidine derivatives
|
Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2014-05-08 |
Pyrrolidine derivatives
|
Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2014-04-25 |
Pyrrolidine derivatives
|
Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2014-04-21 |
作為蛋白質激酶抑制劑之吡唑化合物及噻唑化合物、其醫藥組成物及用途
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Jiaang, WT;Hsu, TA;Lin, WH;Chao, YS |
| 國家衛生研究院 |
2014-02-19 |
Pyrrolidine derivatives
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Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2014-02 |
Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation
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Chung, KM;Hsu, SC;Chu, YR;Lin, MY;Jiaang, WT;Chen, RH;Chen, X |
| 國家衛生研究院 |
2014-01-08 |
Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer
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Lin, WH;Yeh, TK;Jiaang, WT;Yen, KJ;Chen, CH;Huang, CT;Yen, SC;Hsieh, SY;Chou, LH;Chen, CP;Chiu, CH;Kao, LC;Chao, YS;Chen, CT;Hsu, JTA |
| 國家衛生研究院 |
2014-01 |
A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease
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Yang, CC;Hu, HS;Wu, RH;Wu, SH;Lee, SJ;Jiaang, WT;Chern, JH;Huang, ZS;Wu, HN;Chang, CM;Yueh, A |
| 國家衛生研究院 |
2013-12-18 |
吡咯烷化合物
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Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2013-09-27 |
Pyrrolidine derivatives
|
Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2013-06-28 |
Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor
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Shiao, HY;Coumar, MS;Chang, CW;Ke, YY;Chi, YH;Chu, CY;Sun, HY;Chen, CH;Lin, WH;Fung, KS;Kuo, PC;Huang, CT;Chang, KY;Lu, CT;Hsu, JT;Chen, CT;Jiaang, WT;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2013-06 |
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
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Lin, WH;Hsu, JTA;Hsieh, SY;Chen, CT;Song, JS;Yen, SC;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Yang, YN;Chiu, CH;Chen, CP;Tseng, YJ;Yen, KJ;Yeh, CF;Chao, YS;Yeh, TK;Jiaang, WT |
| 國家衛生研究院 |
2013-04-30 |
Pyrrolidine derivatives
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Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2013-02-11 |
吡咯啉啶化合物
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Jiaang, WT;Tsai, TY;Hsu, T;Chao, YS |
| 國家衛生研究院 |
2013-02-11 |
吡咯啶化合物
|
Jiaang, WT;Chen, X |
| 國家衛生研究院 |
2013-02 |
Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems
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Lin, HM;Wang, JC;Hu, HS;Wu, PS;Wang, WH;Wu, SY;Yang, CC;Yeh, TK;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yueh, A |
| 國家衛生研究院 |
2012-06-15 |
Pyrrolidine derivatives
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Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2012-06-07 |
3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
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Hsu, JT;Yeh, TK;Yen, SC;Chen, CT;Hsieh, SY;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Chiu, CH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Lin, WH;Jiaang, WT |
| 國家衛生研究院 |
2012-06-05 |
Pyrrolidine derivatives
|
Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2012-04-21 |
吡咯啉啶化合物
|
Jiaang, WT;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2012-01-17 |
Pyrrolidine compounds
|
Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS |
| 國家衛生研究院 |
2012-01 |
Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor
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Lin, HM;Wang, JC;Hu, HS;Wu, PS;Yang, CC;Wu, CP;Pu, SY;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yeh, TK;Yueh, A |
| 國家衛生研究院 |
2012-01 |
BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML
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Lin, WH;Jiaang, WT;Chen, CW;Yen, KJ;Hsieh, SY;Yen, SC;Chen, CP;Chang, KY;Chang, CY;Chang, TY;Huang, YL;Yeh, TK;Chao, YS;Chen, CT;Hsu, JT |
| 國家衛生研究院 |
2011-12-06 |
Pyrrolidine compounds
|
Jiaang, WT;Chen, X |
| 國家衛生研究院 |
2011-09-20 |
Pyrrolidine derivatives
|
Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2011-07 |
Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
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Lin, WH;Hsieh, SY;Yen, SC;Chen, CT;Yeh, TK;Hsu, T;Lu, CT;Chen, CP;Chen, CW;Chou, LH;Huang, YL;Cheng, AH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Hsu, JT;Jiaang, WT |
| 國家衛生研究院 |
2011-06 |
Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate
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Huang, CH;Suen, CS;Lin, CT;Chien, CH;Lee, HY;Chung, KM;Tsai, TY;Jiaang, WT;Hwang, MJ;Chen, X |
| 國家衛生研究院 |
2011-06 |
Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein
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Chen, SJ;Jiaang, WT |
| 國家衛生研究院 |
2011-05-25 |
Pyrrolidine derivatives
|
Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T |
| 國家衛生研究院 |
2011-02 |
Synthesis of 3,3-dimethylglutamic acid derivatives as DPP-IV inhibitors and evaluation of their chemical stability
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Hsu, T;Tsai, TY;Tseng, YJ;Chiou, MC;Lu, CT;Chao, YS;Jiaang, WT |
| 國家衛生研究院 |
2010-10-06 |
吡咯烷化合物
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Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS |
| 國家衛生研究院 |
2010-09 |
The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activities
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Chung, KM;Cheng, JH;Suen, CS;Huang, CH;Tsai, CH;Huang, LH;Chen, YR;Wang, AH; Jiaang, WT; Hwang, MJ;Chen, X |
| 國家衛生研究院 |
2010-08 |
Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein
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Tsai, TY;Yeh, TK;Chen, X;Hsu, T;Jao, YC;Huang, CH;Song, JS;Huang, YC;Chien, CH;Chiu, JH;Yen, SC;Tang, HK;Chao, YS;Jiaang, WT |
| 國家衛生研究院 |
2010-06-15 |
(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
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Yeh, TK;Tsai, TY;Hsu, T;Cheng, JH;Chen, X;Song, JS;Shy, HS;Chiou, MC;Chien, CH;Tseng, YJ;Huang, CY;Yeh, KC;Huang, YL;Huang, CH;Huang, YW;Wang, MH;Tang, HK;Chao, YS;Chen, CT;Jiaang, WT |
| 國家衛生研究院 |
2010-03-30 |
Pyrrolidine compounds
|
Jiaang, WT;Chen, X;Wu, SY;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2009-10 |
(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases
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Hsu, T;Chen, CT;Tsai, TY;Cheng, JH;Wu, SY;Chang, CN;Chien, CH;Yeh, KC;Huang, YW;Huang, CL;Huang, CY;Wu, SH;Chiang, YK;Wang, MH;Chao, YS;Chen, X;Jiaang, WT |
| 國家衛生研究院 |
2009-07-15 |
Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor
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Wu, JJ;Tang, HK;Yeh, TK;Chen, CM;Shy, HS;Chu, YR;Chien, CH;Tsai, TY;Huang, YC;Huang, YL;Huang, CH;Tseng, HY;Jiaang, WT;Chao, YS;Chen, X |
| 國家衛生研究院 |
2009-06 |
A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]
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Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY |
| 國家衛生研究院 |
2009-04-01 |
Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors
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Tsai, TY;Hsu, T;Chen, CT;Cheng, JH;Chiou, MC;Huang, CH;Tseng, YJ;Yeh, TK;Huang, CY;Yeh, KC;Huang, YW;Wu, SH;Wang, MH;Chen, X;Chao, YS;Jiaang, WT |
| 國家衛生研究院 |
2009-03-15 |
Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors
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Tsai, TY;Hsu, T;Chen, CT;Cheng, JH;Yeh, TK;Chen, X;Huang, CY;Chang, CN;Yeh, KC;Hsieh, SH;Chien, CH;Chang, YW;Huang, CH;Huang, YW;Huang, CL;Wu, SH;Wang, MH;Lu, CT;Chao, YS;Jiaang, WT |
| 國家衛生研究院 |
2009-01-22 |
Pyrrolidine compounds
|
Chao, YS;Chen, X;Hsieh, HP;Jiaang, WT;Wu, SY |
Showing items 26-75 of 86 (2 Page(s) Totally)
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