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机构	日期	题名	作者
國家衛生研究院	2016-02-09	Pyrazole compounds and thiazole compounds as protein kinases inhibitors	Jiaang, WT;Hsu, TA;Lin, WH;Chao, YS
國家衛生研究院	2015-11-13	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2015-07	Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations	Chen, CT;Hsu, JTA;Lin, WH;Lu, CT;Yen, SC;Hsu, T;Huang, YL;Song, JS;Chen, CH;Chou, LH;Yen, KJ;Chen, CP;Kuo, PC;Huang, CL;Eugene Liu, H;Chao, YS;Yeh, TK;Jiaang, WT
國家衛生研究院	2014-08-01	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2014-05-12	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2014-05-08	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2014-04-25	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2014-04-21	作為蛋白質激酶抑制劑之吡唑化合物及噻唑化合物、其醫藥組成物及用途	Jiaang, WT;Hsu, TA;Lin, WH;Chao, YS
國家衛生研究院	2014-02-19	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2014-02	Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation	Chung, KM;Hsu, SC;Chu, YR;Lin, MY;Jiaang, WT;Chen, RH;Chen, X
國家衛生研究院	2014-01-08	Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer	Lin, WH;Yeh, TK;Jiaang, WT;Yen, KJ;Chen, CH;Huang, CT;Yen, SC;Hsieh, SY;Chou, LH;Chen, CP;Chiu, CH;Kao, LC;Chao, YS;Chen, CT;Hsu, JTA
國家衛生研究院	2014-01	A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease	Yang, CC;Hu, HS;Wu, RH;Wu, SH;Lee, SJ;Jiaang, WT;Chern, JH;Huang, ZS;Wu, HN;Chang, CM;Yueh, A
國家衛生研究院	2013-12-18	吡咯烷化合物	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2013-09-27	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2013-06-28	Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor	Shiao, HY;Coumar, MS;Chang, CW;Ke, YY;Chi, YH;Chu, CY;Sun, HY;Chen, CH;Lin, WH;Fung, KS;Kuo, PC;Huang, CT;Chang, KY;Lu, CT;Hsu, JT;Chen, CT;Jiaang, WT;Chao, YS;Hsieh, HP
國家衛生研究院	2013-06	Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Lin, WH;Hsu, JTA;Hsieh, SY;Chen, CT;Song, JS;Yen, SC;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Yang, YN;Chiu, CH;Chen, CP;Tseng, YJ;Yen, KJ;Yeh, CF;Chao, YS;Yeh, TK;Jiaang, WT
國家衛生研究院	2013-04-30	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2013-02-11	吡咯啉啶化合物	Jiaang, WT;Tsai, TY;Hsu, T;Chao, YS
國家衛生研究院	2013-02-11	吡咯啶化合物	Jiaang, WT;Chen, X
國家衛生研究院	2013-02	Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems	Lin, HM;Wang, JC;Hu, HS;Wu, PS;Wang, WH;Wu, SY;Yang, CC;Yeh, TK;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yueh, A
國家衛生研究院	2012-06-15	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2012-06-07	3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Hsu, JT;Yeh, TK;Yen, SC;Chen, CT;Hsieh, SY;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Chiu, CH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Lin, WH;Jiaang, WT
國家衛生研究院	2012-06-05	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2012-04-21	吡咯啉啶化合物	Jiaang, WT;Chao, YS;Hsieh, HP
國家衛生研究院	2012-01-17	Pyrrolidine compounds	Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院	2012-01	Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor	Lin, HM;Wang, JC;Hu, HS;Wu, PS;Yang, CC;Wu, CP;Pu, SY;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yeh, TK;Yueh, A
國家衛生研究院	2012-01	BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML	Lin, WH;Jiaang, WT;Chen, CW;Yen, KJ;Hsieh, SY;Yen, SC;Chen, CP;Chang, KY;Chang, CY;Chang, TY;Huang, YL;Yeh, TK;Chao, YS;Chen, CT;Hsu, JT
國家衛生研究院	2011-12-06	Pyrrolidine compounds	Jiaang, WT;Chen, X
國家衛生研究院	2011-09-20	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2011-07	Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Lin, WH;Hsieh, SY;Yen, SC;Chen, CT;Yeh, TK;Hsu, T;Lu, CT;Chen, CP;Chen, CW;Chou, LH;Huang, YL;Cheng, AH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Hsu, JT;Jiaang, WT
國家衛生研究院	2011-06	Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate	Huang, CH;Suen, CS;Lin, CT;Chien, CH;Lee, HY;Chung, KM;Tsai, TY;Jiaang, WT;Hwang, MJ;Chen, X
國家衛生研究院	2011-06	Current advances and therapeutic potential of agents targeting dipeptidyl peptidases-IV, -II, 8/9 and fibroblast activation protein	Chen, SJ;Jiaang, WT
國家衛生研究院	2011-05-25	Pyrrolidine derivatives	Jiaang, WT;Chao, YS;Tsai, TY;Hsu, T
國家衛生研究院	2011-02	Synthesis of 3,3-dimethylglutamic acid derivatives as DPP-IV inhibitors and evaluation of their chemical stability	Hsu, T;Tsai, TY;Tseng, YJ;Chiou, MC;Lu, CT;Chao, YS;Jiaang, WT
國家衛生研究院	2010-10-06	吡咯烷化合物	Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院	2010-09	The dimeric transmembrane domain of prolyl dipeptidase DPP-IV contributes to its quaternary structure and enzymatic activities	Chung, KM;Cheng, JH;Suen, CS;Huang, CH;Tsai, CH;Huang, LH;Chen, YR;Wang, AH; Jiaang, WT; Hwang, MJ;Chen, X
國家衛生研究院	2010-08	Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein	Tsai, TY;Yeh, TK;Chen, X;Hsu, T;Jao, YC;Huang, CH;Song, JS;Huang, YC;Chien, CH;Chiu, JH;Yen, SC;Tang, HK;Chao, YS;Jiaang, WT
國家衛生研究院	2010-06-15	(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV	Yeh, TK;Tsai, TY;Hsu, T;Cheng, JH;Chen, X;Song, JS;Shy, HS;Chiou, MC;Chien, CH;Tseng, YJ;Huang, CY;Yeh, KC;Huang, YL;Huang, CH;Huang, YW;Wang, MH;Tang, HK;Chao, YS;Chen, CT;Jiaang, WT
國家衛生研究院	2010-03-30	Pyrrolidine compounds	Jiaang, WT;Chen, X;Wu, SY;Chao, YS;Hsieh, HP
國家衛生研究院	2009-10	(1,3-Diphenyl-1H-pyrazol-4-yl)-methylamine analogues as inhibitors of dipeptidyl peptidases	Hsu, T;Chen, CT;Tsai, TY;Cheng, JH;Wu, SY;Chang, CN;Chien, CH;Yeh, KC;Huang, YW;Huang, CL;Huang, CY;Wu, SH;Chiang, YK;Wang, MH;Chao, YS;Chen, X;Jiaang, WT
國家衛生研究院	2009-07-15	Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor	Wu, JJ;Tang, HK;Yeh, TK;Chen, CM;Shy, HS;Chu, YR;Chien, CH;Tsai, TY;Huang, YC;Huang, YL;Huang, CH;Tseng, HY;Jiaang, WT;Chao, YS;Chen, X
國家衛生研究院	2009-06	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.]	Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY
國家衛生研究院	2009-04-01	Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors	Tsai, TY;Hsu, T;Chen, CT;Cheng, JH;Chiou, MC;Huang, CH;Tseng, YJ;Yeh, TK;Huang, CY;Yeh, KC;Huang, YW;Wu, SH;Wang, MH;Chen, X;Chao, YS;Jiaang, WT
國家衛生研究院	2009-03-15	Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors	Tsai, TY;Hsu, T;Chen, CT;Cheng, JH;Yeh, TK;Chen, X;Huang, CY;Chang, CN;Yeh, KC;Hsieh, SH;Chien, CH;Chang, YW;Huang, CH;Huang, YW;Huang, CL;Wu, SH;Wang, MH;Lu, CT;Chao, YS;Jiaang, WT
國家衛生研究院	2009-01-22	Pyrrolidine compounds	Chao, YS;Chen, X;Hsieh, HP;Jiaang, WT;Wu, SY
國家衛生研究院	2008-09-16	Pyrrolidine compounds	Jiaang, WT;Chao, YS;Hsieh, HP
國家衛生研究院	2008-08	A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors	Lu, IL;Tsai, KC;Chiang, YK;Jiaang, WT;Wu, SH;Mahindroo, N;Chien, CH;Lee, SJ;Chen, X;Chao, YS;Wu, SY
國家衛生研究院	2008-07-21	吡咯啉啶化合物	Jiaang, WT;Wu, SY;Chen, X;Chao, YS;Hsieh, HP
國家衛生研究院	2008-07-01	Pyrrolidine compounds	Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院	2007-03-01	3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes	Coumar, MS; Chang, CN; Chen, CT; Chen, X; Chien, CH; Tsai, TY; Cheng, JH; Wu, HY; Han, CH; Wu, SH; Huang, YW; Hsu, T; Hsu, LJ; Chao, YS; Hsieh, HP; Jiaang, WT

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