| 臺大學術典藏 |
2021-06-02T05:43:36Z |
Structural studies and anticancer activity of a novel class of β-peptides
|
Kudryavtsev K.V.; Yu C.-C.; Ivantcova P.M.; Polshakov V.I.; Churakov A.V.; Br?se S.; Zefirov N.S.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:36Z |
Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma
|
Hsu J.-L.; Liu F.-L.; Hsu L.-C.; Chang H.-S.; Leu W.-J.; Yu C.-C.; Chang W.-L.; Chen I.-S.; Kung F.-L.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:35Z |
Cytotoxic protobassic acid glycosides from Planchonella obovata leaf
|
Chen H.-Y.; JIH-HWA GUH; Chan S.-H.; Lee S.-S. |
| 臺大學術典藏 |
2021-06-02T05:43:35Z |
Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer - A crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation
|
Chang W.-L.;Hsu L.-C.;Leu W.-J.;Chen C.-S.;Jih-Hwa Guh; Chang W.-L.; Hsu L.-C.; Leu W.-J.; Chen C.-S.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:35Z |
Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway
|
Ho C.-H.; Hsu J.-L.; Liu S.-P.; Hsu L.-C.; Chang W.-L.; Chao C.C.-K.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:34Z |
KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora a activity
|
Yu C.-C.; Liu S.-P.; Hsu J.-L.; Hsu J.T.A.; Kudryavtsev K.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:33Z |
Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c[[1,2,5]thiadiazole-6,11-dione derivatives as promising scaffold of antitumor agents
|
Lee Y.-R.; Chen T.-C.; Lee C.-C.; Chen C.-L.; Ahmed Ali A.A.; Tikhomirov A.; JIH-HWA GUH; Yu D.-S.; Huang H.-S. |
| 臺大學術典藏 |
2021-06-02T05:43:33Z |
Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells - A critical role of Cdk1 in mitotic entry
|
Chang W.-L.; Yu C.-C.; Chen C.-S.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:33Z |
Catalytic transfer hydrogenation and anticancer activity of arene-ruthenium compounds incorporating bi-dentate precursors
|
Chang Y.-H.; Leu W.-J.; Datta A.; Hsiao H.-C.; Lin C.-H.; JIH-HWA GUH; Huang J.-H. |
| 臺大學術典藏 |
2021-06-02T05:43:32Z |
Non-immunosuppressive triazole-based small molecule induces anticancer activity against human hormone-refractory prostate cancers: The role in inhibition of PI3K/AKT/mTOR and c-Myc signaling pathways
|
Leu W.-J.; Swain S.P.; Chan S.-H.; Hsu J.-L.; Liu S.-P.; Chan M.-L.; Yu C.-C.; Hsu L.-C.; Chou Y.-L.; Chang W.-L.; Hou D.-R.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:32Z |
Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline Hexamers
|
Kudryavtsev K.V.; Ivantcova P.M.; Muhle-Goll C.; Churakov A.V.; Sokolov M.N.; Dyuba A.V.; Arutyunyan A.M.; Howard J.A.K.; Yu C.-C.; JIH-HWA GUH; Zefirov N.S.; Br?se S. |
| 臺大學術典藏 |
2021-06-02T05:43:32Z |
Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insult
|
Chan M.-L.; Liang J.-W.; Hsu L.-C.; Chang W.-L.; Lee S.-S.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:31Z |
Hemiasterlin derivative (R)(S)(S)-BF65 and Akt inhibitor MK-2206 synergistically inhibit SKOV3 ovarian cancer cell growth
|
Lai W.-T.; Cheng K.-L.; Baruchello R.; Rondanin R.; Marchetti P.; Simoni D.; Lee R.M.; JIH-HWA GUH; Hsu L.-C. |
| 臺大學術典藏 |
2021-06-02T05:43:31Z |
Synthesis and characterization of ruthenium compounds incorporating keto-amine ligands. The applications of catalytic transfer hydrogenation and cancer cell inhibition
|
Lin T.-H.; Das K.; Datta A.; Leu W.-J.; Hsiao H.-C.; Lin C.-H.; JIH-HWA GUH; Huang J.-H. |
| 臺大學術典藏 |
2021-06-02T05:43:30Z |
ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5
|
Sun H.-L.; Cui R.; Zhou J.; Teng K.-Y.; Hsiao Y.-H.; Nakanishi K.; Fassan M.; Luo Z.; Shi G.; Tili E.; Kutay H.; Lovat F.; Vicentini C.; Huang H.-L.; Wang S.-W.; Kim T.; Zanesi N.; Jeon Y.-J.; Lee T.J.; JIH-HWA GUH; Hung M.-C.; Ghoshal K.; Teng C.-M.; Peng Y.; Croce C.M. |
| 臺大學術典藏 |
2021-06-02T05:43:30Z |
Enantiomerically pure β-dipeptide derivative induces anticancer activity against human hormone-refractory prostate cancer through both PI3K/Akt-dependent and -independent pathways
|
Chan M.-L.; Yu C.-C.; Hsu J.-L.; Leu W.-J.; Chan S.-H.; Hsu L.-C.; Liu S.-P.; Ivantcova P.M.; Dogan ?.; Br?se S.; Kudryavtsev K.V.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:29Z |
An integrated approach to elucidate signaling pathways of dioscin-induced apoptosis, energy metabolism and differentiation in acute myeloid leukemia
|
Chan S.-H.; Liang P.-H.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:29Z |
Design, synthesis and cytotoxic activity of N-Modified oleanolic saponins bearing A glucosamine
|
Lin Y.-Y.; Chan S.-H.; Juang Y.-P.; Hsiao H.-M.; JIH-HWA GUH; Liang P.-H. |
| 臺大學術典藏 |
2021-06-02T05:43:29Z |
Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities
|
Chao S.-W.; Chen L.-C.; Yu C.-C.; Liu C.-Y.; Lin T.E.; JIH-HWA GUH; Wang C.-Y.; Chen C.-Y.; Hsu K.-C.; Huang W.-J. |
| 臺大學術典藏 |
2021-06-02T05:43:28Z |
Retraction of: Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators (Journal of Medicinal Chemistry (2010) 53:6 (2552-2561): DOI: 10.1021/jm901773d)
|
JIH-HWA GUH; Chang W.-L.; Yang J.; Lee S.-L.; Wei S.; Wang D.; Kulp S.K.; Chen C.-S. |
| 臺大學術典藏 |
2021-06-02T05:43:27Z |
Para-toluenesulfonamide induces anti-tumor activity through Akt-dependent and -independent mTOR/p70S6K pathway: Roles of lipid raft and cholesterol contents
|
Hsu J.-L.; Leu W.-J.; Hsu L.-C.; Liu S.-P.; Zhong N.-S.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:27Z |
Synthesis, characterization and cancer cell growth inhibition activity of ruthenium(II) complexes bearing bidentate pyrrole-imine ligands
|
Chen G.-H.; Leu W.-J.; JIH-HWA GUH; Lin C.-H.; Huang J.-H. |
| 臺大學術典藏 |
2021-06-02T05:43:27Z |
Ruthenium (II) complexes containing dehydroacetic acid and its imine derivative ligands. Synthesis, characterization and cancer cell growth anti-proliferation activity (GI50) study
|
Chen K.-H.; Lin T.-H.; Hsu T.-E.; Li Y.-J.; Chen G.-H.; Leu W.-J.; JIH-HWA GUH; Lin C.-H.; Huang J.-H. |
| 臺大學術典藏 |
2021-06-02T05:43:26Z |
The combination of MK-2206 and WZB117 exerts a synergistic cytotoxic effect against breast cancer cells
|
Li Y.-L.;Weng H.-C.;Hsu J.-L.;Lin S.-W.;Jih-Hwa Guh;Hsu L.-C.; Li Y.-L.; Weng H.-C.; Hsu J.-L.; Lin S.-W.; JIH-HWA GUH; Hsu L.-C. |
| 臺大學術典藏 |
2021-06-02T05:43:26Z |
Phosphodiesterase type 5 (PDE5) inhibitors sensitize topoisomerase II inhibitors in killing prostate cancer through PDE5-independent impairment of HR and NHEJ DNA repair systems
|
Chang J.-F.;Hsu J.-L.;Sheng Y.-H.;Leu W.-J.;Yu C.-C.;Chan S.-H.;Chan M.-L.;Hsu L.-C.;Liu S.-P.;Jih-Hwa Guh; Chang J.-F.; Hsu J.-L.; Sheng Y.-H.; Leu W.-J.; Yu C.-C.; Chan S.-H.; Chan M.-L.; Hsu L.-C.; Liu S.-P.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:25Z |
Extract from plectranthus amboinicus inhibit maturation and release of interleukin 1β through inhibition of NF-κB nuclear translocation and NLRP3 inflammasome activation
|
Leu W.-J.;Chen J.-C.;Jih-Hwa Guh; Leu W.-J.; Chen J.-C.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:22Z |
Dihydroartemisinin–Bile Acid Hybridization as an Effective Approach to Enhance Dihydroartemisinin Anticancer Activity
|
Marchesi E.;Chinaglia N.;Capobianco M.L.;Marchetti P.;Huang T.-E.;Weng H.-C.;Jih-Hwa Guh;Hsu L.-C.;Perrone D.;Navacchia M.L.; Marchesi E.; Chinaglia N.; Capobianco M.L.; Marchetti P.; Huang T.-E.; Weng H.-C.; JIH-HWA GUH; Hsu L.-C.; Perrone D.; Navacchia M.L. |
| 臺大學術典藏 |
2021-06-02T05:43:21Z |
Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agents
|
Chen T.-C.;Jih-Hwa Guh;Hsu H.-W.;Chen C.-L.;Lee C.-C.;Wu C.-L.;Lee Y.-R.;Lin J.-J.;Yu D.-S.;Huang H.-S.; Chen T.-C.; JIH-HWA GUH; Hsu H.-W.; Chen C.-L.; Lee C.-C.; Wu C.-L.; Lee Y.-R.; Lin J.-J.; Yu D.-S.; Huang H.-S. |
| 臺大學術典藏 |
2021-06-02T05:43:21Z |
Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents
|
Chen T.-C.;Yu D.-S.;Chen S.-J.;Chen C.-L.;Lee C.-C.;Hsieh Y.-Y.;Chang L.-C.;Jih-Hwa Guh;Lin J.-J.;Huang H.-S.; Chen T.-C.; Yu D.-S.; Chen S.-J.; Chen C.-L.; Lee C.-C.; Hsieh Y.-Y.; Chang L.-C.; JIH-HWA GUH; Lin J.-J.; Huang H.-S. |
| 臺大學術典藏 |
2021-06-02T05:43:20Z |
Mechanistic study of triazole based aminodiol derivatives in leukemic cells—crosstalk between mitochondrial stress-involved apoptosis and autophagy
|
Chan S.-H.;Leu W.-J.;Swain S.P.;Hsu J.-L.;Hou D.-R.;Jih-Hwa Guh; Chan S.-H.; Leu W.-J.; Swain S.P.; Hsu J.-L.; Hou D.-R.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:20Z |
Ascleposide, a natural cardenolide, induces anticancer signaling in human castration-resistant prostatic cancer through Na+/K+-ATPase internalization and tubulin acetylation
|
Leu W.-J.;Wang C.-T.;Hsu J.-L.;Chen I.-S.;Chang H.-S.;Jih-Hwa Guh; Leu W.-J.; Wang C.-T.; Hsu J.-L.; Chen I.-S.; Chang H.-S.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:20Z |
Discovery of novel agents on spindle assembly checkpoint to sensitize vinorelbine-induced mitotic cell death against human non-small cell lung cancers
|
Chang Y.-C.;Tseng Y.-L.;Leu W.-J.;Du C.-M.;Jiang Y.-H.;Hsu L.-C.;Hsu J.-L.;Hou D.-R.;Jih-Hwa Guh; Chang Y.-C.; Tseng Y.-L.; Leu W.-J.; Du C.-M.; Jiang Y.-H.; Hsu L.-C.; Hsu J.-L.; Hou D.-R.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:19Z |
The (+)-brevipolide H displays anticancer activity against human castration-resistant prostate cancer: The role of oxidative stress and Akt/mTOR/p70S6K dependent pathways in G1 checkpoint arrest and apoptosis
|
Sheng Y.-H.; Leu W.-J.; Chen C.-N.; Hsu J.-L.; Liu Y.-T.; Hsu L.-C.; Hou D.-R.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:19Z |
Synthesis, distribution analysis and mechanism studies of N-acyl glucosamine-bearing oleanolic saponins
|
Juang Y.-P.;Lin Y.-Y.;Chan S.-H.;Chang C.-K.;Shie J.-J.;Hsieh Y.S.Y.;Jih-Hwa Guh;Liang P.-H.; Juang Y.-P.; Lin Y.-Y.; Chan S.-H.; Chang C.-K.; Shie J.-J.; Hsieh Y.S.Y.; JIH-HWA GUH; Liang P.-H. |
| 臺大學術典藏 |
2021-06-02T05:43:17Z |
Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells
|
Huang T.-E.;Deng Y.-N.;Hsu J.-L.;Leu W.-J.;Marchesi E.;Capobianco M.L.;Marchetti P.;Navacchia M.L.;Jih-Hwa Guh;Perrone D.;Hsu L.-C.; Huang T.-E.; Deng Y.-N.; Hsu J.-L.; Leu W.-J.; Marchesi E.; Capobianco M.L.; Marchetti P.; Navacchia M.L.; JIH-HWA GUH; Perrone D.; Hsu L.-C. |
| 臺大學術典藏 |
2021-06-02T05:43:17Z |
Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling
|
Hsu J.-L.;Leu W.-J.;Hsu L.-C.;Ho C.-H.;Liu S.-P.;Jih-Hwa Guh; Hsu J.-L.; Leu W.-J.; Hsu L.-C.; Ho C.-H.; Liu S.-P.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:16Z |
Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
|
Wang Y.; Zhang L.; Wei Y.; Huang W.; Li L.; Wu A.-A.; Dastur A.; Greninger P.; Bray W.M.; Zhang C.-S.; Li M.; Lian W.; Hu Z.; Wang X.; Liu G.; Yao L.; JIH-HWA GUH; Chen L.; Wang H.-R.; Zhou D.; Lin S.-C.; Xu Q.; Shen Y.; Zhang J.; Jurica M.S.; Benes C.H.; Deng X. |
| 臺大學術典藏 |
2021-06-02T05:43:13Z |
Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies
|
Leu W.-J.;Chu J.-C.;Hsu J.-L.;Du C.-M.;Jiang Y.-H.;Hsu L.-C.;Huang W.-J.;Jih-Hwa Guh; Leu W.-J.; Chu J.-C.; Hsu J.-L.; Du C.-M.; Jiang Y.-H.; Hsu L.-C.; Huang W.-J.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-05-28T01:35:00Z |
Cephalochromin induces G0/G1 cell cycle arrest and apoptosis in A549 human non-small-cell lung cancer cells by inflicting mitochondrial disruption
|
Che-Jen Hsiao, George Hsiao, Wei-Lin Chen, Shih-Wei Wang, Chun-Ping Chiang, Li-Ya Liu, Jih-Hwa Guh, Tzong-Huei Lee, and Chi-Li Chung; Che-Jen Hsiao; George Hsiao; Wei-Lin Chen; Shih-Wei Wang; Chun-Ping Chiang; Li-Ya Liu; Jih-Hwa Guh; Tzong-Huei Lee; Chi-Li Chung |
| 臺大學術典藏 |
2021-05-28T01:34:59Z |
Pycnidione, a fungus-derived agent, induces cell cycle arrest and apoptosis in A549 human lung cancer cells
|
Che-Jen Hsiao, Shih-Hsin Hsiao, Wei-Lin Chen, Jih-Hwa Guh, George Hsiao, Yen-Ju Chan, Tzong-Huei Lee, Chi-Li Chung; Che-Jen Hsiao; Shih-Hsin Hsiao; Wei-Lin Chen; Jih-Hwa Guh; George Hsiao; Yen-Ju Chan; Tzong-Huei Lee; Chi-Li Chung |
| 臺大學術典藏 |
2021-01-18T09:12:04Z |
Chalcones Display Anti-NLRP3 Inflammasome Activity in Macrophages through Inhibition of Both Priming and Activation Steps-Structure-Activity-Relationship and Mechanism Studies
|
Leu, Wohn Jenn; Chu, Jung Chun; Hsu, Jui Ling; Du, Chi Min; Jiang, Yi Huei; LIH-CHING HSU; Huang, Wei Jan; JIH-HWA GUH |
| 臺大學術典藏 |
2021-01-09T09:25:20Z |
Synthesis, distribution analysis and mechanism studies of N-acyl glucosamine-bearing oleanolic saponins
|
Juang, Yu-Pu; Lin, You-Yu; Chan, She-Hung; Chang, Chun-Kai; Shie, Jiun-Jie; Hsieh, Yves S Y; JIH-HWA GUH; PI-HUI LIANG |
| 臺大學術典藏 |
2018-09-10T15:27:37Z |
Design, synthesis and biological evaluation of tetracyclic azafluorenone derivatives with topoisomerase I inhibitory properties as potential anticancer agents
|
Chen, T.-C.;Yu, D.-S.;Chen, S.-J.;Chen, C.-L.;Lee, C.-C.;Hsieh, Y.-Y.;Chang, L.-C.;Guh, J.-H.;Lin, J.-J.;Huang, H.-S.; JIH-HWA GUH; JING-JER LIN |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Menthols as Chiral Auxiliaries for Asymmetric Cycloadditive Oligomerization: Syntheses and Studies of β-Proline Hexamers
|
Kudryavtsev, K.V.;Ivantcova, P.M.;Muhle-Goll, C.;Churakov, A.V.;Sokolov, M.N.;Dyuba, A.V.;Arutyunyan, A.M.;Howard, J.A.K.;Yu, C.-C.;Guh, J.-H.;Zefirov, N.S.;Br\\Ase, S.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Repurposing of nitroxoline as a potential anticancer agent against human prostate cancer - A crucial role on AMPK/mTOR signaling pathway and the interplay with Chk2 activation
|
Chang, W.-L.;Hsu, L.-C.;Leu, W.-J.;Chen, C.-S.;Guh, J.-H.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c[[1,2,5]thiadiazole-6,11-dione derivatives as promising scaffold of antitumor agents
|
Lee, Y.-R.;Chen, T.-C.;Lee, C.-C.;Chen, C.-L.;Ahmed Ali, A.A.;Tikhomirov, A.;Guh, J.-H.;Yu, D.-S.;Huang, H.-S.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Structural studies and anticancer activity of a novel class of β-peptides
|
Kudryavtsev, K.V.;Yu, C.-C.;Ivantcova, P.M.;Polshakov, V.I.;Churakov, A.V.;Br\\Ase, S.;Zefirov, N.S.;Guh, J.-H.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:46Z |
Tubulin-binding agents down-regulate matrix metalloproteinase-2 and -9 in human hormone-refractory prostate cancer cells - A critical role of Cdk1 in mitotic entry
|
Chang, W.-L.;Yu, C.-C.;Chen, C.-S.;Guh, J.-H.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:45Z |
Catalytic transfer hydrogenation and anticancer activity of arene-ruthenium compounds incorporating bi-dentate precursors
|
Chang, Y.-H.;Leu, W.-J.;Datta, A.;Hsiao, H.-C.;Lin, C.-H.;Guh, J.-H.;Huang, J.-H.; JIH-HWA GUH |
| 臺大學術典藏 |
2018-09-10T15:26:43Z |
Zerumbone, a ginger sesquiterpene, induces apoptosis and autophagy in human hormone-refractory prostate cancers through tubulin binding and crosstalk between endoplasmic reticulum stress and mitochondrial insult
|
Chan, M.-L.;Liang, J.-W.;Hsu, L.-C.;Chang, W.-L.;Lee, S.-S.;Guh, J.-H.; JIH-HWA GUH; SHOEI-SHENG LEE |
