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Institution Date Title Author
臺大學術典藏 2022-05-12T05:25:29Z Drug Repurposing for the Identification of Compounds with Anti-SARS-CoV-2 Capability via Multiple Targets Yu, Pei-Chen; Huang, Chen-Hao; Kuo, Chih-Jung; Liang, Po-Huang; Wang, Lily Hui-Ching; Pan, Max Yu-Chen; SUI-YUAN CHANG; Chao, Tai-Ling; Ieong, Si-Man; Fang, Jun-Tung; Huang, Hsuan-Cheng; Juan, Hsueh-Fen
臺大學術典藏 2022-02-14T23:55:36Z Drug Repurposing for the Identification of Compounds with Anti-SARS-CoV-2 Capability via Multiple Targets YU-PEI CHEN; Huang, Chen Hao; Kuo, Chih Jung; Liang, Po Huang; Wang, Lily Hui Ching; Pan, Max Yu Chen; SUI-YUAN CHANG; Chao, Tai Ling; Ieong, Si Man; Fang, Jun Tung; Huang, Hsuan Cheng; HSUEH-FEN JUAN
臺大學術典藏 2021-11-07T07:34:09Z Kinetic Characterization and Inhibitor Screening for the Proteases Leading to Identification of Drugs against SARS-CoV-2 Kuo, Chih-Jung; Chao, Tai-Ling; Kao, Han-Chieh; Tsai, Ya-Min; Liu, Yi-Kai; Wang, Lily Hui-Ching; Hsieh, Ming-Chang; SUI-YUAN CHANG; Liang, Po-Huang
臺大學術典藏 2021-03-17T02:29:26Z Uncovering Flexible Active Site Conformations of SARS-CoV-2 3CL Proteases through Protease Pharmacophore Clusters and COVID-19 Drug Repurposing Pathak, Nikhil; Chen, Yun-Ti; Hsu, Yen-Chao; Hsu, Nung-Yu; Kuo, Chih-Jung; Tsai, Hui Ping; Huang, Chih-Heng; SUI-YUAN CHANG; Chang, Yu-Hsiu; Liang, Po-Huang; Yang, Jinn-Moon; JAW-JOU KANG
臺大學術典藏 2018-09-10T08:36:28Z Fluorescent substrate analog for monitoring chain elongation by undecaprenyl pyrophosphate synthase in real time Teng, Kuo-Hsun;Chen, Annie P.-C.;Kuo, Chih-Jung;Li, Yu-Chin;Liu, Hon-Ge;Chen, Chao-Tsen;Liang, Po-Huang; Teng, Kuo-Hsun; Chen, Annie P.-C.; Kuo, Chih-Jung; Li, Yu-Chin; Liu, Hon-Ge; Chen, Chao-Tsen; Liang, Po-Huang; CHAO-TSEN CHEN
臺大學術典藏 2018-09-10T06:38:40Z Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus Wen, Chih-Chun; Kuo, Yueh-Hsiung; Jan, Jia-Tsrong; Liang, Po-Huang; Wang, Sheng-Yang; Liu, Hong-Gi; Lee, Ching-Kuo; Chang, Shang-Tzen; Kuo, Chih-Jung; Lee, Shoei-Sheng; Hou, Chia-Chung; Hsiao, Pei-Wen; Chien, Shih-Chang; Shyur, Lie-Fen; Yang, Ning-Sun; Wen, C.-C.; SHOEI-SHENG LEE et al.; Wen, Chih-Chun; Kuo, Yueh-Hsiung; Jan, Jia-Tsrong; Liang, Po-Huang; Wang, Sheng-Yang; Liu, Hong-Gi; Lee, Ching-Kuo; Chang, Shang-Tzen; Kuo, Chih-Jung; Lee, Shoei-Sheng; Hou, Chia-Chung; Hsiao, Pei-Wen; Chien, Shih-Chang; Shyur, Lie-Fen; Yang, Ning-Sun
國立交通大學 2014-12-12T02:39:21Z 蛋白質間交互作用小分子抑制劑選擇性促使化學藥劑抗藥性或缺乏半胱胺酸蛋白酶-3之癌細胞死亡 陳世勳; Chen, Shih-Hsun; 楊進木; 梁博煌; Yang, Jinn-Moon; Liang, Po-Huang
國立交通大學 2014-12-08T15:34:25Z Moiety-Linkage Map Reveals Selective Nonbisphosphonate Inhibitors of Human Geranylgeranyl Diphosphate Synthase Chen, Shih-Hsun; Lin, Sheng-Wei; Lin, Shen-Rong; Liang, Po-Huang; Yang, Jinn-Moon
國立交通大學 2014-12-08T15:34:09Z Conjugation of Benzylvanillin and Benzimidazole Structure Improves DNA Binding with Enhanced Antileukemic Properties Al-Mudaris, Zena A.; Majid, Aman S. A.; Ji, Dan; Al-Mudarris, Ban A.; Chen, Shih-Hsun; Liang, Po-Huang; Osman, Hasnah; Din, Shah Kamal Khan Jamal; Majid, Amin M. S. Abdul
國立交通大學 2014-12-08T15:32:27Z Targeting the XIAP/caspase-7 complex selectively kills caspase-3-deficient malignancies Lin, Yuan-Feng; Lai, Tsung-Ching; Chang, Chih-Kang; Chen, Chi-Long; Huang, Ming-Shyan; Yang, Chih-Jen; Liu, Hon-Ge; Dong, Jhih-Jhong; Chou, Yi-An; Teng, Kuo-Hsun; Chen, Shih-Hsun; Tian, Wei-Ting; Jan, Yi-Hua; Hsiao, Michael; Liang, Po-Huang
國立交通大學 2014-12-08T15:22:42Z Roles of Amino Acids in the Escherichia coli Octaprenyl Diphosphate Synthase Active Site Probed by Structure-Guided Site-Directed Mutagenesis Chang, Keng-Ming; Chen, Shih-Hsun; Kuo, Chih-Jung; Chang, Chi-Kang; Guo, Rey-Ting; Yang, Jinn-Moon; Liang, Po-Huang
國立交通大學 2014-12-08T15:09:45Z Combined Experimental and Theoretical Study of Long-Range Interactions Modulating Dimerization and Activity of Yeast Geranylgeranyl Diphosphate Synthase Lo, Chia-Hsiang; Chang, Ying-Hsuan; Wright, Jon D.; Chen, Shih-Hsun; Kan, Daphne; Lim, Carmay; Liang, Po-Huang
國立臺灣大學 2012 Roles of Amino Acids in the Escherichia coli Octaprenyl Diphosphate Synthase Active Site Probed by Structure-Guided Site-Directed Mutagenesis Chang, Keng-Ming; Chen, Shih-Hsun; Kuo, Chih-Jung; Chang, Chi-Kang; Guo, Rey-Ting; Yang, Jinn-Moon; Liang, Po-Huang
國立臺灣大學 2011 Fluorescent substrate analog for monitoring chain elongation by undecaprenyl pyrophosphate synthase in real time Teng, Kuo-Hsun; Chen, Annie P.-C.; Kuo, Chih-Jung; Li, Yu-Chin; Liu, Hon-Ge; Chen, Chao-Tsen; Liang, Po-Huang
國立臺灣大學 2011 Structural and functional analysis of three beta-glucosidases from bacterium Clostridium cellulovorans, fungus Trichoderma reesei and termite Neotermes koshunensis Jeng, Wen-Yih; Wang, Nai-Chen; Lin, Man-Hua; Lin, Cheng-Tse; Liaw, Yen-Chywan; Chang, Wei-Jung; Liu, Chia-I; Liang, Po-Huang; Wang, Andrew H-J.
國立臺灣大學 2010 Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors Ramajayam, R.; Tan, Kian-Pin; Liu, Hun-Ge; Liang, Po-Huang
國立臺灣大學 2010 Mechanism of cis-prenyltransferase reaction probed by substrate analogues Lu, Yen-Pin; Liu, Hon-Ge; Teng, Kuo-Hsun; Liang, Po-Huang
國立臺灣大學 2010 Synthesis, docking studies, and evaluation of pyrimidines as inhibitors of SARS-CoV 3CL protease Ramajayam, R.; Tan, Kian-Pin; Liu, Hun-Ge; Liang, Po-Huang
國立臺灣大學 2010 Structure of a Heterotetrameric Geranyl Pyrophosphate Synthase from Mint (Mentha piperita) Reveals Intersubunit Regulation Chang, Tao-Hsin; Hsieh, Fu-Lien; Ko, Tzu-Ping; Teng, Kuo-Hsun; Liang, Po-Huang; Wang, Andrew H-J.
國立臺灣大學 2009 Different reaction mechanisms for cis- and trans-prenyltransferases Lu, Yen-Pin; Liu, Hun-Ge; Liang, Po-Huang
國立臺灣大學 2009 Corrigendum to “Individual and common inhibitors of coronavirus and picornavirus main proteases” [FEBS Lett. 583 (2009) 549–555] Kuo, Chih-Jung; Liu, Hun-Ge; Lo, Yueh-Kuei; Seong, Churl-Min; Lee, Kee-In; Jung, Young-Sik; Liang, Po-Huang
國立臺灣大學 2009 Combined Experimental and Theoretical Study of Long-Range Interactions Modulating Dimerization and Activity of Yeast Geranylgeranyl Diphosphate Synthase Lo, Chia-Hsiang; Chang, Ying-Hsuan; Wright, Jon D.; Chen, Shih-Hsun; Kan, Daphne; Lim, Carmay; Liang, Po-Huang
國立臺灣大學 2009 Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds Lee, Cheng-Chung; Kuo, Chih-Jung; Ko, Tzu-Ping; Hsu, Min-Feng; Tsui, Yao-Chen; Chang, Shih-Cheng; Yang, Syaulan; Chen, Shu-Jen; Chen, Hua-Chien; Hsu, Ming-Chu; Shih, Shin-Ru; Liang, Po-Huang; Wang, Andrew H.-J.
國立臺灣大學 2008 A mammalian cell-based reverse two-hybrid system for functional analysis of 3C viral protease of human enterovirus 71 Lee, Jin-Ching; Shih, Shin-Ru; Chang, Ten-Yuan; Tseng, Huan-Yi; Shih, Ya-Feng; Yen, Kuei-Jung; Chen, Wei-Chun; Shie, Jiun-Jie; Fang, Jim-Min; Liang, Po-Huang; Chao, Yu-Sheng; Hsu, John T-A.
國立臺灣大學 2008 Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease Shao, Yi-Ming; Yang, Wen-Bin; Kuo, Tun-Hsun; Tsai, Keng-Chang; Lin, Chun-Hung; Yang, An-Suei; Liang, Po-Huang; Wong, Chi-Huey

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