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Institution Date Title Author
國家衛生研究院 2024-09-20 The mitochondrial stress signaling tunes immunity from a view of systemic tumor microenvironment and ecosystem Kuo, CL;Lin, YC;Lo, YK;Lu, YZ;Babuharisankar, AP;Lien, HW;Chou, HY;Lee, AY
國家衛生研究院 2022-09-26 Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend? Kuo, CL;Ponneri Babuharisankar, A;Lin, YC;Lien, HW;Lo, YK;Chou, HY;Tangeda, V;Cheng, LC;Cheng, AN;Lee, AY
國家衛生研究院 2022-03-16 Lon upregulation contributes to cisplatin resistance by triggering NCLX-mediated mitochondrial Ca2+ release in cancer cells Tangeda, V;Lo, YK;Babuharisankar, AP;Chou, HY;Kuo, CL;Kao, YH;Lee, AYL;Chang, JY
國家衛生研究院 2020-12 Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1-mediated immunoescape via STING-IFN signaling and extracellular vesicles Cheng, AN;Cheng, LC;Kuo, CL;Lo, YK;Chou, HY;Chen, CH;Wang, YH;Chuang, TH;Cheng, SJ;Lee, AY
國家衛生研究院 2018-10 Identification of novel Cdc7 kinase inhibitors as anti-cancer agents that target the interaction with Dbf4 by the fragment complementation and drug repositioning approach Cheng, AN;Lo, YK;Lin, YS;Tang, TK;Hsu, CH;Hsu, JTA;Lee, AYL
國家衛生研究院 2018-06-13 Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity Sung, YJ;Kao, TY;Kuo, CL;Fan, CC;Cheng, AN;Fang, WC;Chou, HY;Lo, YK;Chen, CH;Jiang, SS;Chang, IS;Hsu, CH;Lee, JC;Lee, AY
國家衛生研究院 2017-12 Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer Cheng, AN;Fan, CC;Lo, YK;Kuo, CL;Wang, HC;Lien, IH;Lin, SY;Chen, CH;Jiang, SS;Chang, IS;Juan, HF;Lyu, PC;Lee, AYL
國家衛生研究院 2016-05 Loss of GDF10/BMP3b as a prognostic marker collaborates with TGFBR3 to enhance chemotherapy resistance and epithelial-mesenchymal transition in oral squamous cell carcinoma Cheng, CW;Hsiao, JR;Fan, CC;Lo, YK;Tzen, CY;Wu, LW;Fang, WY;Cheng, AJ;Chen, CH;Chang, IS;Jiang, SS;Chang, JY;Lee, AY
國家衛生研究院 2014-08 Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition (EMT) in zebrafish Chen, CH;Lin, DS;Cheng, CW;Lin, CJ;Lo, YK;Yen, CC;Lee, AY;Hsiao, CD
國家衛生研究院 2013-09 Increased Cdc7 expression is a marker of oral squamous cell carcinoma and overexpression of Cdc7 contributes to the resistance to DNA-damaging agents Cheng, AN;Jiang, SS;Fan, CC;Lo, YK;Kuo, CY;Chen, CH;Liu, YL;Lee, CC;Chen, WS;Huang, TS;Wang, TY;Lee, AYL

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