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Institution Date Title Author
國家衛生研究院 2025-05-20 Structure-based design of potent and selective merTK inhibitors by modulating the conformation of alphaC helix Peng, YH;Li, MC;Yen, WC;Yeh, TK;Hsueh, CC;Kuo, FM;Lai, YL;Chang, L;Lee, LC;Chen, PY;Yen, KJ;Chang, TY;Sun, HY;Chang, CY;Hsieh, SH;Yang, CM;Hsieh, HP;Wu, SY
國家衛生研究院 2024-11-26 Development of potent and selective inhibitors of methylenetetrahydrofolate dehydrogenase 2 for targeting acute myeloid leukemia: Sar, structural insights, and biological characterization Chang, HH;Lee, LC;Hsu, T;Peng, YH;Huang, CH;Yeh, TK;Lu, CT;Huang, ZT;Hsueh, CC;Kung, FC;Lin, LM;Huang, YC;Wang, YH;Li, LH;Tang, YC;Chang, L;Hsieh, CC;Jiaang, WT;Kuo, CC;Wu, SY
國家衛生研究院 2024-06-07 Enhancing ionic selectivity and osmotic energy by using an ultrathin Zr-MOF-based heterogeneous membrane with trilayered continuous porous structure Yang, ZJ;Yeh, LH;Peng, YH;Chuang, YP;Wu, KC
國家衛生研究院 2024-02-13 Age at onset of type 1 diabetes between puberty and 30 years old is associated with increased diabetic nephropathy risk Lin, YB;Chang, TJ;Sheu, WHH;Lo, SH;Yeh, YP;Huang, CN;Hwu, CM;Hsieh, CH;Ou, HY;Chuang, LM;Chen, JF;Chen, YC;Peng, YH;Chen, ST;Hsu, SR;Hsieh, YL;Chu, CH;Lu, CH;Lee, YJ;Chen, HF;Chen, CC;Lee, CC;Hsiao, PJ;Tsai, ST;Chen, S;Su, CC;Lin, YL;Bau, CT;Liao, CC;Kuo, TY;Chen, HJ;Wang, CC;Cheng, CJ;Lin, YL;Chen, SC;Chen, CY;Huang, HY;Chen, JR;Lo, HJ;Yu, NC;Liu, WC;Wu, CH;Chen, DW;Shen, DC;Chung, WC
國家衛生研究院 2022-02-05 Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design Yeh, TK;Song, JS;Chang, PW;Yu, JC;Chang, CH;Liao, FY;Tien, YW;Kuppusamy, R;Li, AS;Chen, CH;Chen, CW;Lin, LM;Chang, HH;Huang, CH;Yao, JY;Wu, MH;Peng, YH;Hsueh, CC;Hsiao, WC;Chen, PH;Lin, CY;Hsieh, SH;Shih, C;Hung, MS;Wu, SY;Kuo, CC;Ueng, SH
國家衛生研究院 2021-08-12 Xanthine derivatives reveal an allosteric binding site in methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) Lee, LC;Peng, YH;Chang, HH;Hsu, T;Lu, CT;Huang, CH;Hsueh, CC;Kung, FC;Kuo, CC;Jiaang, WT;Wu, SY
國家衛生研究院 2020-02-10 Unique sulfur-aromatic interactions contribute to the binding of potent imidazothiazole indoleamine 2,3-Dioxygenase inhibitors Peng, YH;Liao, FY;Tseng, CT;Kuppusamy, R;Li, AS;Chen, CH;Fan, YS;Wang, SY;Wu, MH;Hsueh, CC;Chang, JY;Lee, LC;Shih, C;Shia, KS;Yeh, TK;Hung, MS;Kuo, CC;Song, JS;Wu, SY;Ueng, SH
國家衛生研究院 2019-12 Identification of a multitargeted tyrosine kinase inhibitor for the treatment of gastrointestinal stromal tumors and acute myeloid leukemia Lin, WH;Wu, SY;Yeh, TK;Chen, CT;Song, JS;Shiao, HY;Kuo, CC;Hsu, T;Lu, CT;Wang, PC;Wu, TS;Peng, YH;Lin, HY;Chen, CP;Weng, YL;Kung, FC;Wu, MH;Su, YC;Huang, KW;Chou, LH;Hsueh, CC;Yen, KJ;Kuo, PC;Huang, CL;Chen, LT;Shih, C;Tsai, HJ;Jiaang, WT
國家衛生研究院 2019-09-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer Lin, SY;Chang Hsu, Y;Peng, YH;Ke, YY;Lin, WH;Sun, HY;Shiao, HY;Kuo, FM;Chen, PY;Lien, TW;Chen, CH;Chu, CY;Wang, SY;Yeh, KC;Chen, CP;Hsu, TA;Wu, SY;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2019-04-10 Discovery of Conformational Control Inhibitors Switching off the Activated c-KIT and Targeting a Broad Range of Clinically Relevant c-KIT Mutants Wu, TS;Lin, WH;Tsai, HJ;Hsueh, CC;Hsu, T;Wang, PC;Lin, HY;Peng, YH;Lu, CT;Lee, LC;Tu, CH;Kung, FC;Shiao, HY;Yeh, TK;Song, JS;Chang, JY;Su, YC;Chen, LT;Chen, CT;Jiaang, WT;Wu, SY
國家衛生研究院 2017-03-21 Low-cell-number, single-tube amplification (STA) of total RNA revealed transcriptome changes from pluripotency to endothelium Lee, YH;Hsueh, YW;Peng, YH;Chang, KC;Tsai, KJ;Sun, HS;Su, IJ;Chiang, PM
國家衛生研究院 2016-04-12 Pyrazolylamine derivatives reveal the conformational switching between type I and type II binding modes of Anaplastic Lymphoma Kinase (ALK) Tu, CH;Lin, WH;Peng, YH;Hsu, T;Wu, JS;Chang, CY;Lu, CT;Lyu, PC;Shih, C;Jiaang, WT;Wu, SY
國家衛生研究院 2016-01 Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1 Peng, YH;Ueng, SH;Tseng, CT;Hung, MS;Song, JS;Wu, JS;Liao, FY;Fan, YS;Wu, MH;Hsiao, WC;Hsueh, CC;Lin, SY;Cheng, CY;Tu, CH;Lee, LC;Cheng, MF;Shia, KS;Shih, C;Wu, SY
國家衛生研究院 2016-01 Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy Lin, SY;Yeh, TK;Kuo, CC;Song, JS;Cheng, MF;Liao, FY;Chao, MW;Huang, HL;Chen, YL;Yang, CY;Wu, MH;Hsieh, CL;Hsiao, WC;Peng, YH;Wu, JS;Lin, LM;Sun, MW;Chao, YS;Shih, C;Wu, SY;Pan, SL;Hung, MS;Ueng, SH
國家衛生研究院 2015-10 Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening Wu, JS;Lin, SY;Liao, FY;Hsiao, WC;Lee, LC;Peng, YH;Hsieh, CL;Wu, MH;Song, JS;Yueh, A;Chen, CH;Yeh, SH;Liu, CY;Lin, SY;Yeh, TK;Hsu, JT;Shih, C;Ueng, SH;Hung, MS;Wu, SY
國立交通大學 2014-12-08T15:44:08Z Optical disk mastering using optical superresolution technique Shieh, HPD; Tsai, SY; Peng, YH; Hsieh, TE
國立交通大學 2014-12-08T15:20:19Z Cost efficiency and the effect of mergers on the Taiwanese banking industry Peng, YH; Wang, KL
臺北醫學大學 2014 Association of Novel Gene Polymorphisms RRM1 ?756T>C and ?269 C>A With Breast Cancer Chen, DR;Chuang, CY;Wu, BC;Yang, SF;Peng, YH;Tsai, HT
國家衛生研究院 2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules Wu, JM;Chen, CT;Coumar, MS;Lin, WH;Chen, ZJ;Hsu, JT;Peng, YH;Shiao, HY;Chu, CY;Wu, JS;Lin, CT;Chen, CP;Hsueh, CC;Chang, KY;Kao, LP;Huang, CY;Chao, YS;Wu, SY;Hsieh, HP;Chi, YH
國家衛生研究院 2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors Peng, YH;Shiao, HY;Tu, CH;Liu, PM;Hsu, JT;Amancha, PK;Wu, JS;Coumar, MS;Chen, CH;Wang, SY;Lin, WH;Sun, HY;Chao, YS;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院 2010-12 Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening Wu, JS;Peng, YH;Wu, JM;Hsieh, CJ;Wu, SH;Coumar, MS;Song, JS;Lee, JC;Tsai, CH;Chen, CT;Liu, YW;Chao, YS;Wu, SY
國家衛生研究院 2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院 2010-06-15 Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院 2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists Lin, CH;Peng, YH;Coumar, MS;Chittimalla, SK;Liao, CC;Lyn, PC;Huang, CC;Lien, TW;Lin, WH;Hsu, JT;Cheng, JH;Chen, X;Wu, JS;Chao, YS;Lee, HJ;Juo, CG;Wu, SY;Hsieh, HP
國立臺灣大學 2008 Electroluminescence enhancement of SiGe/Si multiple quantum wells through nanowall structures Chen, T T; Hsieh, Y P; Wei, C M; Chen, Y F; Chen, L-C; Chen, K-H; Peng, YH; Kuan, C H
國立臺灣大學 2008 A novel dispersant for preparation of high loading and photosensitive carbon black dispersion Kuo, KH; Peng, YH; Chiu, WY; Don, TM
國家衛生研究院 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists Mahindroo, N; Peng, YH; Lin, CH; Tan, UK; Prakash, E; Lien, TW; Lu, IL; Lee, HJ; Hsu, JTA; Chen, X; Liao, CC; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-08-24 Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease Lu, IL; Mahindroo, N; Liang, PH; Peng, YH; Kuo, CJ; Tsai, KC; Hsieh, HP; Chao, YS; Wu, SY
國家衛生研究院 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities Lu, IL; Huang, CF; Peng, YH; Lin, YT; Hsieh, HP; Chen, CT; Lien, TW; Lee, HJ; Mahindroo, N; Prakash, E; Yueh, A; Chen, HY; Goparaju, CMV; Chen, X; Liao, CC; Chao, YS; Hsu, JTA; Wu, SY
國家衛生研究院 2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies Mahindroo, N; Wang, CC; Liao, CC; Huang, CF; Lu, IL; Lien, TW; Peng, YH; Huang, WJ; Lin, YT; Hsu, MC; Lin, CH; Tsai, CH; Hsu, JTA; Chen, X; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities Mahindroo, N; Huang, CF; Peng, YH; Wang, CC; Liao, CC; Lien, TW; Chittimalla, SK; Huang, WJ; Chai, CH; Prakash, E; Chen, CP; Hsu, TA; Peng, CH; Lu, IL; Lee, LH; Chang, YW; Chen, WC; Chou, YC; Chen, CT; Goparaju, CMV; Chen, YS; Lan, SJ; Yu, MC; Chen, X; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents Hsieh, HP;Mahindroo, N;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Peng, YH;Lee, LH;Prakash, E;Chen, WC;Chang, YW;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Lan, SJ;Chao, YS
國立臺灣大學 2002-12 Effects of low-temperature Si buffer layer thickness on the growth of SiGe by molecular beam epitaxy Lee, SW; Chen, HC; Chen, LJ; Peng, YH; Kuan, CH; Cheng, HH
國立臺灣大學 2002-07 Enhanced growth of CoSi2 on epitaxial Si0.7Ge0.3 with a sacrificial amorphous Si interlayer Wu, WW; Chiang, TF; Cheng, SL; Lee, SW; Chen, LJ; Peng, YH; Cheng, HH
國立臺灣大學 2002-01 Population differentiation and gene flow revealed by microsatellite DNA markers in the house mouse (Mus musculus castaneus) in Taiwan. Yu, HT; Peng, YH
國立臺灣大學 2001-06 Inverted hut" structure of Si-Ge nanocrystals studied by extended x-ray absorption fine structure method" Soo, YL; Kioseoglou, G; Huang, S; Kim, S; Kao, YH; Peng, YH; Cheng, HH
臺北醫學大學 2001 A Voice Communication System Using Speech Recognition and Synthesis for Speech Disorder Subjects 徐建業; Peng YH; Hsu CY; Pan LC;
臺北醫學大學 2000 應用語音辨識與合成技術於語言障礙復健之裝置模擬 徐建業; Peng YH; Hsu CY; Pan LC;

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