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Institution Date Title Author
國家衛生研究院 2025-10-01 Synthesis and biological evaluation of indoline derivatives as CDGSH iron sulfur domain 2 activators Yao, CH;Wang, LY;Shen, ZQ;Huang, YW;Tsai, CH;Song, JS;Chen, CH;Chen, YC;Tsai, TF;Lee, JC
國家衛生研究院 2025-03-10 CXCR4 antagonist-loaded nanoparticles reprogram the tumor microenvironment and enhance immunotherapy in hepatocellular carcinoma Cheng, SL;Wu, CH;Tsai, YJ;Song, JS;Chen, HM;Yeh, TK;Shen, CT;Chiang, JC;Lee, HM;Huang, KW;Chen, Y;Qiu, JT;Yen, YT;Shia, KS;Chen, Y
國家衛生研究院 2023-11-15 Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors Chang, PW;Wang, JY;Wang, WP;Huang, WC;Wu, MH;Song, JS;Chen, LY;Tung, CW;Chi, YH;Ueng, SH
國家衛生研究院 2023-11-15 Analysis of structure-activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors Chang, PW;Wang, JY;Wang, WP;Huang, WC;Wu, MH;Song, JS;Chen, LY;Tung, CW;Chi, YH;Ueng, SH
國家衛生研究院 2023-10-05 Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease Yao, CH;Shen, ZQ;Rajan, YC;Huang, YW;Lin, CY;Song, JS;Shiao, HY;Ke, YY;Fan, YS;Tsai, CH;Yeh, TK;Tsai, TF;Lee, JC
國家衛生研究院 2023-02-03 Design, synthesis, and anticancer evaluation of 1-benzo[1,3]dioxol-5-yl-3-N-fused heteroaryl indoles Yao, CH;Wu, MH;Chang, PW;Wu, SH;Song, JS;Huang, HH;Chen, YC;Lee, JC
國家衛生研究院 2023-01 Modulating the affinity and signaling bias of cannabinoid receptor 1 antagonists Hsiao, WC;Hsin, KY;Wu, ZW;Song, JS;Yeh, YN;Chen, YF;Tsai, CH;Chen, PH;Shia, KS;Chang, CP;Hung, MS
國家衛生研究院 2022-10-03 Protective effect of CXCR4 antagonist DBPR807 against ischemia-reperfusion injury in a rat and porcine model of myocardial infarction: Potential adjunctive therapy for percutaneous coronary intervention Yeh, KC;Lee, CJ;Song, JS;Wu, CH;Yeh, TK;Wu, SH;Hsieh, TC;Chen, YT;Tseng, HY;Huang, CL;Chen, CT;Jan, JJ;Chou, MC;Shia, KS;Chiang, KH
國家衛生研究院 2022-08-09 Chemical interference with DSIF complex formation lowers synthesis of mutant huntingtin gene products and curtails mutant phenotypes Deng, N;Wu, YY;Feng, Y;Hsieh, WC;Song, JS;Lin, YS;Tseng, YH;Liao, WJ;Chu, YF;Liu, YC;Chang, EC;Liu, CR;Sheu, SY;Su, MT;Kuo, HC;Cohen, SN;Cheng, TH
國家衛生研究院 2022-02-05 Discovery and development of a novel N-(3-bromophenyl)-{[(phenylcarbamoyl)amino]methyl}-N-hydroxythiophene-2-carboximidamide indoleamine 2,3-dioxygenase inhibitor using knowledge-based drug design Yeh, TK;Song, JS;Chang, PW;Yu, JC;Chang, CH;Liao, FY;Tien, YW;Kuppusamy, R;Li, AS;Chen, CH;Chen, CW;Lin, LM;Chang, HH;Huang, CH;Yao, JY;Wu, MH;Peng, YH;Hsueh, CC;Hsiao, WC;Chen, PH;Lin, CY;Hsieh, SH;Shih, C;Hung, MS;Wu, SY;Kuo, CC;Ueng, SH
國家衛生研究院 2021-10-20 Heterocyclic compounds and use thereof Shih, C;Shih, C;Wu, CH;Choi, Ming Chen;Song, JS;Wang, Y
國家衛生研究院 2021-09-24 Heterocyclic compounds and their application Shih, C;Shia, KS;Wu, CH;Choi, Ming Chen;Song, JS;Wang, Y
國家衛生研究院 2021-08-31 Heterocyclic compounds and use thereof Shih, C;Shia, KS;Wu, CH;Choi, Ming Chen;Song, JS;Wang, Y
國家衛生研究院 2021-08-01 DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activity Yeh, KC;Yeh, TK;Huang, CY;Hu, CB;Wang, MH;Huang, YW;Chou, LH;Ho, HH;Song, JS;Hsu, T;Jiaang, WT;Chao, YS;Chen, CT
國家衛生研究院 2021-05-19 Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins Chi, YH;Yeh, TK;Ke, YY;Lin, WH;Tsai, CH;Wang, WP;Chen, YT;Su, YC;Wang, PC;Chen, YF;Wu, ZW;Yeh, JY;Hung, MC;Wu, MH;Wang, JY;Chen, CP;Song, JS;Shih, C;Chen, CT;Chang, CP
國家衛生研究院 2021-04-01 Heterocyclic compounds and use thereof Shih, C;Shia, KS;Wu, CH;Choi, Ming Chen;Song, JS;Wang, Y
國家衛生研究院 2021-03-30 A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment Song, JS;Chang, CC;Wu, CH;Dinh, TK;Jan, JJ;Huang, KW;Chou, MC;Shiue, TY;Yeh, KC;Ke, YY;Yeh, TK;Ta, YNN;Lee, CJ;Huang, JK;Sung, YC;Shia, KS;Chen, Y
國家衛生研究院 2021-03-02 Total synthesis of landomycins Q and R and related core structures for exploration of the cytotoxicity and antibacterial properties Lai, YH;Mondal, S;Su, HT;Huang, SC;Wu, MH;Huang, I;Yang Lauderdale, TL;Song, JS;Shia, KS;Mong, KK
國家衛生研究院 2021-03-02 Discovery of potential neuroprotective agents against paclitaxel-induced peripheral neuropathy Chen, YF;Wu, CH;Chen, LH;Lee, HW;Lee, JC;Yeh, TK;Chang, JY;Chou, MC;Wu, HL;Lai, YP;Song, JS;Yeh, KC;Chen, CT;Lee, CJ;Shia, KS;Shen, MR
國家衛生研究院 2021-01-05 Heterocyclic compounds and use thereof Shia, KS;Wu, CH;Chou, MC;Song, JS;Wang, Y;Shih, C
國家衛生研究院 2020-10-08 Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery Tsou, LK;Yeh, SH;Ueng, SH;Chang, CP;Song, JS;Wu, MH;Chang, HF;Chen, SR;Shih, C;Chen, CT;Ke, YY
國家衛生研究院 2020-09-25 Protective effect of CXCR4 antagonist CX807 in a rat model of hemorrhagic stroke Yu, SJ;Wu, KJ;Wang, YS;Song, JS;Wu, CH;Jan, JJ;Bae, E;Chen, H;Shia, KS;Wang, Y
國家衛生研究院 2020-08 BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification Chi, YH;Chang, CP;Ke, YY;Lin, WH;Wang, WP;Tsai, CH;Chen, YT;Su, YJ;Hung, MC;Wu, ZW;Wu, MH;Yeh, TK;Chen, CP;Song, JS;Chen, CT;Shih, C
國家衛生研究院 2020-05-15 Artificial intelligence approach fighting COVID-19 with repurposing drugs Ke, YY;Peng, TT;Yeh, TK;Huang, WZ;Chang, SE;Wu, SH;Hung, HC;Hsu, TA;Lee, SJ;Song, JS;Lin, WH;Chiang, TJ;Lin, JH;Sytwu, HK;Chen, CT
國家衛生研究院 2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors Lin, SY;Chang, CF;Coumar, MS;Chen, PY;Kuo, FM;Chen, CH;Li, MC;Lin, WH;Kuo, PC;Wang, SY;Li, AS;Lin, CY;Yang, CM;Yeh, TK;Song, JS;Hsu, JTA;Hsieh, HP

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