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"song js"
Showing items 41-90 of 93 (2 Page(s) Totally)
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| 國家衛生研究院 |
2017-09 |
trans-stilbene C-glycosides: Synthesis by a microwave-assisted heck reaction and evaluation of the SGLT-2 inhibitory activity
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KumarPonnapalli, K;KumarAdak, A;Das, A;Song, JS;Wu, SH;Sun, CM;Lin, CC |
| 國家衛生研究院 |
2017-08-02 |
Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology
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Tsou, LK;Huang, YH;Song, JS;Ke, YY;Huang, JK;Shia, KS |
| 國家衛生研究院 |
2017-07 |
Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors
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Yeh, TK;Kuo, CC;Lee, YZ;Ke, YY;Chu, KF;Hsu, HY;Chang, HY;Liu, YW;Song, JS;Yang, CW;Lin, LM;Sun, MW;Wu, SH;Kuo, PC;Shih, C;Chen, CT;Tsou, LK;Lee, SJ |
| 國家衛生研究院 |
2017-01 |
A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide
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Kang, IJ;Hsu, SJ;Yang, HY;Yeh, TK;Lee, CC;Lee, YC;Tian, YW;Song, JS;Hsu, TA;Chao, YS;Yueh, A;Chern, JH |
| 國家衛生研究院 |
2016-12 |
Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation
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Chang Hsu, Y;Selvaraj Coumar, M;Wang, WC;Shiao, HY;Ke, YY;Lin, WH;Kuo, CC;Chang, CW;Kuo, FM;Chen, PY;Wang, SY;Li, AS;Chen, CH;Kuo, PC;Chen, CP;Wu, MH;Huang, CL;Yen, KJ;Chang, YI;Hsu, JT;Chen, CT;Yeh, TK;Song, JS;Shih, C;Hsieh, HP |
| 國家衛生研究院 |
2016-12 |
Phenyl benzenesulfonylhydrazides: Selective indoleamine 2,3-dioxygenase inhibitors with potent in vivo pharmacodynamic activity and antitumor efficacy
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Ueng, SH;Yeh, TK;Song, JS;Wu, SY;Kuo, CC;Shih, C;Pan, SL;Hung, MS |
| 國家衛生研究院 |
2016-05 |
N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors
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Chu, KF;Yao, CH;Song, JS;Chen, CT;Yeh, TK;Hsieh, TC;Huang, CY;Wang, MH;Wu, SH;Chang, WE;Chao, YS;Lee, JC |
| 國家衛生研究院 |
2016-01 |
Synthesis of (E)-oxindolylidene acetate using tandem palladium-catalyzed Heck and alkoxycarbonylation reactions
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Lin, WJ;Shia, KS;Song, JS;Wu, MH;Li, WT |
| 國家衛生研究院 |
2016-01 |
Important hydrogen bond networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) inhibitor design revealed by crystal structures of imidazoleisoindole derivatives with IDO1
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Peng, YH;Ueng, SH;Tseng, CT;Hung, MS;Song, JS;Wu, JS;Liao, FY;Fan, YS;Wu, MH;Hsiao, WC;Hsueh, CC;Lin, SY;Cheng, CY;Tu, CH;Lee, LC;Cheng, MF;Shia, KS;Shih, C;Wu, SY |
| 國家衛生研究院 |
2016-01 |
Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy
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Lin, SY;Yeh, TK;Kuo, CC;Song, JS;Cheng, MF;Liao, FY;Chao, MW;Huang, HL;Chen, YL;Yang, CY;Wu, MH;Hsieh, CL;Hsiao, WC;Peng, YH;Wu, JS;Lin, LM;Sun, MW;Chao, YS;Shih, C;Wu, SY;Pan, SL;Hung, MS;Ueng, SH |
| 國家衛生研究院 |
2015-10 |
Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening
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Wu, JS;Lin, SY;Liao, FY;Hsiao, WC;Lee, LC;Peng, YH;Hsieh, CL;Wu, MH;Song, JS;Yueh, A;Chen, CH;Yeh, SH;Liu, CY;Lin, SY;Yeh, TK;Hsu, JT;Shih, C;Ueng, SH;Hung, MS;Wu, SY |
| 國家衛生研究院 |
2015-07 |
Development and application of a fluorescent glucose uptake assay for the high-throughput screening of non-glycoside SGLT2 inhibitors
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Wu, SH;Yao, CH;Hsieh, CJ;Liu, YW;Chao, YS;Song, JS;Lee, JC |
| 國家衛生研究院 |
2015-07 |
Pharmacological induction of human fetal globin gene in hydroxyurea-resistant primary adult erythroid cells
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Chou, YC;Chen, RL;Lai, ZS;Song, JS;Chao, YS;Shen, CK |
| 國家衛生研究院 |
2015-07 |
Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations
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Chen, CT;Hsu, JTA;Lin, WH;Lu, CT;Yen, SC;Hsu, T;Huang, YL;Song, JS;Chen, CH;Chou, LH;Yen, KJ;Chen, CP;Kuo, PC;Huang, CL;Eugene Liu, H;Chao, YS;Yeh, TK;Jiaang, WT |
| 國家衛生研究院 |
2015-06-29 |
Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification
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Ke, YY;Singh, VK;Coumar, MS;Hsu, YC;Wang, WC;Song, JS;Chen, CH;Lin, WH;Wu, SH;Hsu, JT;Shih, C;Hsieh, HP |
| 國家衛生研究院 |
2015-06-15 |
Synthesis and evaluation of 3-ylideneoxindole acetamides as potent anticancer agents
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Chiou, CT;Lee, WC;Liao, JH;Cheng, JJ;Lin, LC;Chen, CY;Song, JS;Wu, MH;Shia, KS;Li, WT |
| 國家衛生研究院 |
2015-03 |
Stem cell mobilizers targeting chemokine receptor CXCR4: Renoprotective application in acute kidney injury
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Wu, CH;Song, JS;Chang, KH;Jan, JJ;Chen, CT;Chou, MC;Yeh, KC;Wong, YC;Tseng, CT;Wu, SH;Yeh, CF;Huang, CY;Wang, MH;Sadani, AA;Chang, CP;Cheng, CY;Tsou, LK;Shia, KS |
| 國家衛生研究院 |
2015-02 |
Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors
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Wu, CH;Wang, CJ;Chang, CP;Cheng, YC;Song, JS;Jan, JJ;Chou, MC;Ke, YY;Ma, J;Wong, YC;Hsieh, TC;Tien, YC;Gullen, EA;Lo, CF;Cheng, CY;Liu, YW;Sadani, AA;Tsai, CH;Hsieh, HP;Tsou, LK;Shia, KS |
| 國家衛生研究院 |
2014-08 |
Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors
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Cheng, MF;Hung, MS;Song, JS;Lin, SY;Liao, FY;Wu, MH;Hsiao, W;Hsieh, CL;Wu, JS;Chao, YS;Shih, C;Wu, SY;Ueng, SH |
| 國家衛生研究院 |
2014-08 |
Ligand efficiency based approach for efficient virtual screening of compound libraries
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Ke, YY;Coumar, MS;Shiao, HY;Wang, WC;Chen, CW;Song, JS;Chen, CH;Lin, WH;Wu, SH;Hsu, JT;Chang, CM;Hsieh, HP |
| 國家衛生研究院 |
2013-11-13 |
Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice
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Chang, CP;Wu, CH;Song, JS;Chou, MC;Wong, YC;Lin, Y;Yeh, TK;Sadani, AA;Ou, MH;Chen, KH;Chen, PH;Kuo, PC;Tseng, CT;Chang, KH;Tseng, SL;Chao, YS;Hung, MS;Shia, KS |
| 國家衛生研究院 |
2013-11 |
Synthesis and biological evaluation of novel C-aryl d-glucofuranosides as sodium-dependent glucose co-transporter 2 inhibitors
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Lin, TS;Liw, YW;Song, JS;Hsieh, TC;Yeh, HW;Hsu, LC;Lin, CJ;Wu, SH;Liang, PH |
| 國家衛生研究院 |
2013-11 |
BPR0C305, an orally active microtubule-disrupting anticancer agent
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Li, WT;Yeh, TK;Song, JS;Yang, YN;Chen, TW;Lin, CH;Chen, CP;Shen, CC;Hsieh, CC;Lin, HL;Chao, YS;Chen, CT |
| 國家衛生研究院 |
2013-06 |
Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)
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Lin, WH;Hsu, JTA;Hsieh, SY;Chen, CT;Song, JS;Yen, SC;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Yang, YN;Chiu, CH;Chen, CP;Tseng, YJ;Yen, KJ;Yeh, CF;Chao, YS;Yeh, TK;Jiaang, WT |
| 國家衛生研究院 |
2013-05 |
Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus
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Yang, CC;Tsai, MH;Hu, HS;Pu, SY;Wu, RH;Wu, SH;Lin, HM;Song, JS;Chao, YS;Yueh, A |
| 國家衛生研究院 |
2012-09 |
Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors
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Yao, CH;Song, JS;Chen, CT;Yeh, TK;Hsieh, TC;Wu, SH;Huang, CY;Huang, YL;Wang, MH;Liu, YW;Tsai, CH;Kumar, CR;Lee, JC |
| 國家衛生研究院 |
2012-02 |
Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents
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Li, WT;Hwang, DR;Song, JS;Chen, CP;Chen, TW;Lin, CH;Chuu, JJ;Lien, TW;Hsu, TA;Huang, CL;Tseng, HY;Lin, CC;Lin, HL;Chang, CM;Chao, YS;Chen, CT |
| 國家衛生研究院 |
2012-02 |
Discovery of novel stem cell mobilizers that target the CXCR4 receptor
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Wu, CH;Chang, CP;Song, JS;Jan, JJ;Chou, MC;Wu, SH;Yeh, KC;Wong, YC;Hsieh, CJ;Chen, CT;Kao, TT;Wu, SY;Yeh, CF;Tseng, CT;Chao, YS;Shia, KS |
| 國家衛生研究院 |
2012-01 |
A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors
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Lin, WH;Song, JS;Lien, TW;Chang, CY;Wu, SH;Huang, YW;Chang, TY;Fang, MY;Yen, KJ;Chen, CH;Chu, CY;Hsieh, HP;Chen, YR;Chao, YS;Hsu, JT |
| 國家衛生研究院 |
2011-10-01 |
硒吩化合物及其醫藥組成物
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Shia, KS;Tsao, J;Tai, CL;Hsieh, WP;Hung, MS;Song, JS;Chao, YS |
| 國家衛生研究院 |
2011-08-11 |
噁二唑化合物
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Shia, KS;Tsao, JP;Song, JS;Chu, CM;Chao, YS |
| 國家衛生研究院 |
2011-01-13 |
Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes
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Yao, CH;Song, JS;Chen, CT;Yeh, TK;Hung, MS;Chang, CC;Liu, YW;Yuan, MC;Hsieh, CJ;Huang, CY;Wang, MH;Chiu, CH;Hsieh, TC;Wu, SH;Hsiao, WC;Chu, KF;Tsai, CH;Chao, YS;Lee, JC |
| 國家衛生研究院 |
2011-01 |
BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities
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Hu, CB;Chen, CP;Yeh, TK;Song, JS;Chang, CY;Chuu, JJ;Tung, FF;Ho, PY;Chen, TW;Lin, CH;Wang, MH;Chang, KY;Huang, CL;Lin, HL;Li, WT;Hwang, DR;Chern, JH;Hwang, LL;Chang, JY;Chao, YS;Chen, CT |
| 國家衛生研究院 |
2010-12 |
Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening
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Wu, JS;Peng, YH;Wu, JM;Hsieh, CJ;Wu, SH;Coumar, MS;Song, JS;Lee, JC;Tsai, CH;Chen, CT;Liu, YW;Chao, YS;Wu, SY |
| 國家衛生研究院 |
2010-09-28 |
Selenophene compounds
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Shia, KS;Tsao, JP;Tai, CL;Hsieh, WP;Hung, MS;Song, JS;Chao, YS |
| 國家衛生研究院 |
2010-09 |
Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist
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Hung, MS;Chang, CP;Li, TC;Yeh, TK;Song, JS;Lin, Y;Wu, CH;Kuo, PC;Amancha, PK;Wong, YC;Hsiao, WC;Chao, YS;Shia, KS |
| 國家衛生研究院 |
2010-08 |
Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein
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Tsai, TY;Yeh, TK;Chen, X;Hsu, T;Jao, YC;Huang, CH;Song, JS;Huang, YC;Chien, CH;Chiu, JH;Yen, SC;Tang, HK;Chao, YS;Jiaang, WT |
| 國家衛生研究院 |
2010-07 |
Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075
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Chen, CP;Hu, CB;Yeh, KC;Song, JS;Yeh, TK;Tung, FF;Hwang, LL;Tseng, HY;Huang, YC;Shy, HS;Hsieh, SH;Shen, CC;Wang, HS;Hsieh, HP;Liou, JP;Chao, YS;Chen, CT |
| 國家衛生研究院 |
2010-06-15 |
(2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
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Yeh, TK;Tsai, TY;Hsu, T;Cheng, JH;Chen, X;Song, JS;Shy, HS;Chiou, MC;Chien, CH;Tseng, YJ;Huang, CY;Yeh, KC;Huang, YL;Huang, CH;Huang, YW;Wang, MH;Tang, HK;Chao, YS;Chen, CT;Jiaang, WT |
| 國家衛生研究院 |
2010-06-15 |
Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification
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Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2010-04-27 |
Oxadiazole compounds
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Shia, KS;Chu, CM;Tsao, JP;Chao, YS;Song, JS |
| 國家衛生研究院 |
2010-03 |
Synthesis and biological activities of 2-Amino-1-arylidenamino imidazoles as orally active anticancer agents
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Li, WT;Hwang, DR;Song, JS;Chen, CP;Chuu, JJ;Hu, CB;Lin, HL;Huang, CL;Huang, CY;Tseng, HY;Lin, CC;Chen, TW;Lin, CH;Wang, HS;Shen, CC;Chang, CM;Chao, YS;Chen, CT |
| 國家衛生研究院 |
2009-09 |
Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development
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Hsieh, HP;Coumarrs, MS;Chu, CY;Ho, YL;Tsai, MT;Lin, WH;Chen, CH;Song, JS;Hsu, JTA;Chao, YS |
| 國家衛生研究院 |
2009-07-23 |
Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice
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Wu, CH;Hung, MS;Song, JS;Yeh, TK;Chou, MC;Chu, CM;Jan, JJ;Hsieh, MT;Tseng, SL;Chang, CP;Hsieh, WP;Lin, Y;Yeh, YN;Chung, WL;Kuo, CW;Lin, CY;Shy, HS;Chao, YS;Shia, KS |
| 國家衛生研究院 |
2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity
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Chiang, YK;Kuo, CC;Wu, YS;Chen, CT;Coumar, MS;Wu, JS;Hsieh, HP;Chang, CY;Jseng, HY;Wu, MH;Leou, JS;Song, JS;Chang, JY;Lyu, PC;Chao, YS;Wu, SY |
| 國家衛生研究院 |
2008-09-21 |
Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists
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Chu, CM;Hung, MS;Hsieh, MT;Kuo, CW;Suja, TD;Song, JS;Chiu, HH;Chao, YS;Shia, KS |
| 國家衛生研究院 |
2008-09-11 |
Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists
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Tseng, SL;Hung, MS;Chang, CP;Song, JS;Tai, CL;Chiu, HH;Hsieh, WP;Lin, Y;Chung, WL;Kuo, CW;Wu, CH;Chu, CM;Tung, YS;Chao, YS;Shia, KS |
| 國家衛生研究院 |
2008-06-01 |
A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors
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Lin, WH; Song, JS; Chang, TY; Chang, CY; Fu, YN; Yeh, CL; Wu, SH; Huang, YW; Fang, MY; Lien, TW; Hsieh, HP; Chao, YS; Huang, SF; Tsai, SF; Wang, LM; Hsu, JTA; Chen, YR |
| 國家衛生研究院 |
2008-02-07 |
Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists
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Tai, CL; Hung, MS; Pawar, VD; Tseng, SL; Song, JS; Hsieh, WP; Chiu, HH; Wu, HC; Hsieh, MT; Kuo, CW; Hsieh, CC; Tsao, JP; Chao, YS; Shia, KS |
| 國家衛生研究院 |
2003-06-15 |
Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent
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Chang, JY; Hsieh, HP; Pan, WY; Liou, JP; Bey, SJ; Chen, LT; Liu, JF; Song, JS |
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