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Institution Date Title Author
國家衛生研究院 2024-11-08 Endosomes serve as signaling platforms for RIG-I ubiquitination and activation Chen, KR;Yang, CY;Shu, SG;Lo, YC;Lee, KW;Wang, LC;Chen, JB;Shih, MC;Chang, HC;Hsiao, YJ;Wu, CL;Tan, TH;Ling, P
國家衛生研究院 2024-09 The role of dual specificity phosphatase 22 (DUSP22) in rheumatoid arthritis: Mechanism and genetic investigations Hung, WT;Chen, YM;Huang, WN;Yen, TH;Tan, TH;Chuang, HC
國家衛生研究院 2024-06-14 DUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling Lin, HH;Chang, CW;Liao, YT;Yeh, SD;Lin, HP;Ho, HM;Cheung, CHY;Juan, HF;Chen, YR;Su, YW;Chen, LM;Tan, TH;Lin, WJ
國家衛生研究院 2024-06 UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis Chuang, HC;Lan, KY;Hsu, PM;Chen, MH;Chen, YM;Yen, JH;Liao, BY;Tan, TH
國家衛生研究院 2024-05-01 Sequential regulation of Lck K63-ubiquitination and autophosphorylation by the E3 ligase UBR2 and the phosphatase DUSP22 in TCR signaling Tan, TH;Chuang, HC
國家衛生研究院 2024-05-01 DUSP8 promotes IL-9 transcription by inactivating Pur-alpha leading to asthma and atopic dermatitis Chuang, HC;Tan, TH
國家衛生研究院 2024-05-01 Machine learning reveals UHRF-X as a biomarker for systemic lupus erythematosus and an antagonistic protein against UHRF1 E3 ligase Chuang, HC;Tan, TH
國家衛生研究院 2024-03-27 Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck Chyuan, IT;Liao, HJ;Tan, TH;Chuang, HC;Chu, YC;Pan, MH;Wu, CS;Chu, CL;Sheu, BC;Hsu, PN
國家衛生研究院 2024-01-15 The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling Shih, YC;Chen, HF;Wu, CY;Ciou, YR;Wang, CW;Chuang, HC;Tan, TH
國家衛生研究院 2023-12-05 Dual-specificity phosphatase 6 deficiency attenuates arterial-injury-induced intimal hyperplasia in mice Hamdin, CD;Wu, ML;Chen, CM;Ho, YC;Jiang, WC;Gung, PY;Ho, HH;Chuang, HC;Tan, TH;Yet, SF
國家衛生研究院 2023-11-01 DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha Chuang, HC;Hsueh, CH;Hsu, PM;Tsai, CY;Shih, YC;Chiu, HY;Chen, YM;Yu, WK;Chen, MH;Tan, TH
國家衛生研究院 2023-08-22 ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification Wang, CW;Chuang, HC;Tan, TH
國家衛生研究院 2023-05-04 Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia Wang, H;Moniruzzaman, R;Li, L;Ji, B;Liu, Y;Zuo, X;Abbasgholizadeh, R;Zhao, J;Liu, G;Wang, R;Tang, H;Sun, R;Su, X;Tan, TH;Maitra, A;Wang, H
國家衛生研究院 2023-05-01 DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor Chuang, HC;Tan, TH
國家衛生研究院 2023-04-22 DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia Weng, YC;Huang, YT;Chiang, IC;Chuang, HC;Lee, TH;Tan, TH;Chou, WH
國家衛生研究院 2023-02-10 Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis Chen, MH;Chuang, HC;Yeh, YC;Chou, CT;Tan, TH
國家衛生研究院 2022-07-27 SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19 Chuang, HC;Hsueh, CH;Hsu, PM;Huang, RH;Tsai, CY;Chung, NH;Chow, YH;Tan, TH
國家衛生研究院 2022-07-18 MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation Chi, JN;Yang, JY;Hsueh, CH;Tsai, CY;Chuang, HC;Tan, TH
國家衛生研究院 2022-06-15 DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction Chou, HC;Cheng, CM;Yang, CH;Lin, TY;Liu, YW;Tan, TH;Chen, YR
國家衛生研究院 2022-06-14 AhR-ROR-γt complex as a biomarker and therapeutic target for autoimmune disease and IL-17A-associated disease Tan, TH;Chuang, HC
國家衛生研究院 2022-02-18 Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice Chang, CS;Yu, WH;Su, CC;Ruan, JW;Lin, CM;Huang, CT;Tsai, YT;Lin, IJ;Lai, CY;Chuang, TH;Lin, WJ;Tan, TH;Huang, HC;Juan, HF;Kao, CY
國家衛生研究院 2021-11-23 Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice Chang, CS; Liao, YC; Huang, CT; Lin, CM; Cheung, CHY; Ruan, JW; Yu, WH; Tsai, YT; Lin, IJ; Huang, CH; Liou, JS; Chou, YH; Chien, HJ; Chuang, HL; Juan, HF; Huang, HC; Chan, HL; Liao, YC; Tang, SC; Su, YW; Tan, TH; Bäumler, AJ; Kao, CY
國家衛生研究院 2021-10-25 BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus Chuang, HC;Chen, MH;Chen, YM;Yang, HY;Ciou, YR;Hsueh, CH;Tsai, CY;Tan, TH
國家衛生研究院 2021-10-05 Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus Chuang, HC;Hung, WT;Chen, YM;Hsu, PM;Yen, JH;Lan, JL;Tan, TH
國家衛生研究院 2021-07-05 ECP overexpression in T cells and exosomes induces IFN-gamma production and tissue inflammation Chuang, HC;Chen, MH;Chen, YM;Ciou, YR;Hsueh, CH;Tsai, CY;Tan, TH

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