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Institution Date Title Author
國家衛生研究院 2023-11-01 DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha Chuang, HC;Hsueh, CH;Hsu, PM;Tsai, CY;Shih, YC;Chiu, HY;Chen, YM;Yu, WK;Chen, MH;Tan, TH
國家衛生研究院 2023-08-22 ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification Wang, CW;Chuang, HC;Tan, TH
國家衛生研究院 2023-05-04 Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia Wang, H;Moniruzzaman, R;Li, L;Ji, B;Liu, Y;Zuo, X;Abbasgholizadeh, R;Zhao, J;Liu, G;Wang, R;Tang, H;Sun, R;Su, X;Tan, TH;Maitra, A;Wang, H
國家衛生研究院 2023-05-01 DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor Chuang, HC;Tan, TH
國家衛生研究院 2023-04-22 DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia Weng, YC;Huang, YT;Chiang, IC;Chuang, HC;Lee, TH;Tan, TH;Chou, WH
國家衛生研究院 2023-02-10 Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis Chen, MH;Chuang, HC;Yeh, YC;Chou, CT;Tan, TH
國家衛生研究院 2022-07-27 SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19 Chuang, HC;Hsueh, CH;Hsu, PM;Huang, RH;Tsai, CY;Chung, NH;Chow, YH;Tan, TH
國家衛生研究院 2022-07-18 MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation Chi, JN;Yang, JY;Hsueh, CH;Tsai, CY;Chuang, HC;Tan, TH
國家衛生研究院 2022-06-15 DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction Chou, HC;Cheng, CM;Yang, CH;Lin, TY;Liu, YW;Tan, TH;Chen, YR
國家衛生研究院 2022-06-14 AhR-ROR-γt complex as a biomarker and therapeutic target for autoimmune disease and IL-17A-associated disease Tan, TH;Chuang, HC
國家衛生研究院 2022-02-18 Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice Chang, CS;Yu, WH;Su, CC;Ruan, JW;Lin, CM;Huang, CT;Tsai, YT;Lin, IJ;Lai, CY;Chuang, TH;Lin, WJ;Tan, TH;Huang, HC;Juan, HF;Kao, CY
國家衛生研究院 2021-11-23 Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice Chang, CS; Liao, YC; Huang, CT; Lin, CM; Cheung, CHY; Ruan, JW; Yu, WH; Tsai, YT; Lin, IJ; Huang, CH; Liou, JS; Chou, YH; Chien, HJ; Chuang, HL; Juan, HF; Huang, HC; Chan, HL; Liao, YC; Tang, SC; Su, YW; Tan, TH; Bäumler, AJ; Kao, CY
國家衛生研究院 2021-10-25 BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus Chuang, HC;Chen, MH;Chen, YM;Yang, HY;Ciou, YR;Hsueh, CH;Tsai, CY;Tan, TH
國家衛生研究院 2021-10-05 Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus Chuang, HC;Hung, WT;Chen, YM;Hsu, PM;Yen, JH;Lan, JL;Tan, TH
國家衛生研究院 2021-07-05 ECP overexpression in T cells and exosomes induces IFN-gamma production and tissue inflammation Chuang, HC;Chen, MH;Chen, YM;Ciou, YR;Hsueh, CH;Tsai, CY;Tan, TH
國家衛生研究院 2020-10-12 Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases Lai, CH;Chang, CC;Chuang, HC;Tan, TH;Lyu, PC
國家衛生研究院 2020-08-12 DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1 Yang, CY;Chuang, HC;Tsai, CY;Xiao, YZ;Yang, JY;Huang, RH;Shih, YC;Tan, TH
國家衛生研究院 2019-12 DUSP22 suppresses prostate cancer proliferation by targeting the EGFR-AR axis Lin, HP;Ho, HM;Chang, CW;Yeh, SD;Su, YW;Tan, TH;Lin, WJ
國家衛生研究院 2019-11-13 MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus Chuang, HC;Tan, TH
國家衛生研究院 2019-10-22 MAP4K3/GLK in autoimmune disease, cancer and aging Chuang, HC;Tan, TH
國家衛生研究院 2019-08-20 MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1 Chuang, HC;Chang, CC;Teng, CF;Hsueh, CH;Chiu, LL;Hsu, PM;Lee, MC;Hsu, CP;Chen, YR;Liu, YC;Lyu, PC;Tan, TH
國家衛生研究院 2019-07-18 AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus Chuang, HC;Chen, YM;Chen, MH;Hung, WT;Yang, HY;Tseng, YH;Tan, TH
國家衛生研究院 2019-05-30 Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability Chen, HF;Chuang, HC;Tan, TH
國家衛生研究院 2019-05 MAP4K3/GLK-induced AhR-RORyt complex is a novel therapeutic target for GLIC(high)IL-17A(high) subpopulation of SLE patients Chuang, HC;Tan, TH
國家衛生研究院 2019-05 Control of mucosal barrier functions and gut microbiome homeostasis by DUSP6 in colitis Kao, CY;Chang, CS;Liao, YC;Huang, CT;Ruan, JW;Lin, CM;Tan, TH;Liao, YC

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