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臺灣學術機構典藏系統 (Taiwan Academic Institutional Repository, TAIR)
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Institution Date Title Author
國家衛生研究院 2023-11-01 DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha Chuang, HC;Hsueh, CH;Hsu, PM;Tsai, CY;Shih, YC;Chiu, HY;Chen, YM;Yu, WK;Chen, MH;Tan, TH
國家衛生研究院 2023-08-22 ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification Wang, CW;Chuang, HC;Tan, TH
國家衛生研究院 2023-05-04 Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia Wang, H;Moniruzzaman, R;Li, L;Ji, B;Liu, Y;Zuo, X;Abbasgholizadeh, R;Zhao, J;Liu, G;Wang, R;Tang, H;Sun, R;Su, X;Tan, TH;Maitra, A;Wang, H
國家衛生研究院 2023-05-01 DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor Chuang, HC;Tan, TH
國家衛生研究院 2023-04-22 DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia Weng, YC;Huang, YT;Chiang, IC;Chuang, HC;Lee, TH;Tan, TH;Chou, WH
國家衛生研究院 2023-02-10 Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis Chen, MH;Chuang, HC;Yeh, YC;Chou, CT;Tan, TH
國家衛生研究院 2022-07-27 SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19 Chuang, HC;Hsueh, CH;Hsu, PM;Huang, RH;Tsai, CY;Chung, NH;Chow, YH;Tan, TH
國家衛生研究院 2022-07-18 MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation Chi, JN;Yang, JY;Hsueh, CH;Tsai, CY;Chuang, HC;Tan, TH
國家衛生研究院 2022-06-15 DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction Chou, HC;Cheng, CM;Yang, CH;Lin, TY;Liu, YW;Tan, TH;Chen, YR
國家衛生研究院 2022-06-14 AhR-ROR-γt complex as a biomarker and therapeutic target for autoimmune disease and IL-17A-associated disease Tan, TH;Chuang, HC
國家衛生研究院 2022-02-18 Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice Chang, CS;Yu, WH;Su, CC;Ruan, JW;Lin, CM;Huang, CT;Tsai, YT;Lin, IJ;Lai, CY;Chuang, TH;Lin, WJ;Tan, TH;Huang, HC;Juan, HF;Kao, CY
國家衛生研究院 2021-11-23 Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice Chang, CS; Liao, YC; Huang, CT; Lin, CM; Cheung, CHY; Ruan, JW; Yu, WH; Tsai, YT; Lin, IJ; Huang, CH; Liou, JS; Chou, YH; Chien, HJ; Chuang, HL; Juan, HF; Huang, HC; Chan, HL; Liao, YC; Tang, SC; Su, YW; Tan, TH; Bäumler, AJ; Kao, CY
國家衛生研究院 2021-10-25 BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus Chuang, HC;Chen, MH;Chen, YM;Yang, HY;Ciou, YR;Hsueh, CH;Tsai, CY;Tan, TH
國家衛生研究院 2021-10-05 Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus Chuang, HC;Hung, WT;Chen, YM;Hsu, PM;Yen, JH;Lan, JL;Tan, TH
國家衛生研究院 2021-07-05 ECP overexpression in T cells and exosomes induces IFN-gamma production and tissue inflammation Chuang, HC;Chen, MH;Chen, YM;Ciou, YR;Hsueh, CH;Tsai, CY;Tan, TH
國家衛生研究院 2020-10-12 Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases Lai, CH;Chang, CC;Chuang, HC;Tan, TH;Lyu, PC
國家衛生研究院 2020-08-12 DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1 Yang, CY;Chuang, HC;Tsai, CY;Xiao, YZ;Yang, JY;Huang, RH;Shih, YC;Tan, TH
國家衛生研究院 2019-12 DUSP22 suppresses prostate cancer proliferation by targeting the EGFR-AR axis Lin, HP;Ho, HM;Chang, CW;Yeh, SD;Su, YW;Tan, TH;Lin, WJ
國家衛生研究院 2019-11-13 MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus Chuang, HC;Tan, TH
國家衛生研究院 2019-10-22 MAP4K3/GLK in autoimmune disease, cancer and aging Chuang, HC;Tan, TH
國家衛生研究院 2019-08-20 MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1 Chuang, HC;Chang, CC;Teng, CF;Hsueh, CH;Chiu, LL;Hsu, PM;Lee, MC;Hsu, CP;Chen, YR;Liu, YC;Lyu, PC;Tan, TH
國家衛生研究院 2019-07-18 AhR-ROR-gammat complex is a therapeutic target for MAP4K3/GLK(high)IL-17A(high) subpopulation of systemic lupus erythematosus Chuang, HC;Chen, YM;Chen, MH;Hung, WT;Yang, HY;Tseng, YH;Tan, TH
國家衛生研究院 2019-05-30 Regulation of Dual-Specificity Phosphatase (DUSP) ubiquitination and protein stability Chen, HF;Chuang, HC;Tan, TH
國家衛生研究院 2019-05 MAP4K3/GLK-induced AhR-RORyt complex is a novel therapeutic target for GLIC(high)IL-17A(high) subpopulation of SLE patients Chuang, HC;Tan, TH
國家衛生研究院 2019-05 Control of mucosal barrier functions and gut microbiome homeostasis by DUSP6 in colitis Kao, CY;Chang, CS;Liao, YC;Huang, CT;Ruan, JW;Lin, CM;Tan, TH;Liao, YC
國家衛生研究院 2019-05 T-cell signaling in Th17-mediated inflammation Tan, TH;Chuang, HC
國家衛生研究院 2019-03-01 MAP4K4 inhibition promotes survival of human stem cell-derived cardiomyocytes and reduces infarct size in vivo Fiedler, LR;Chapman, K;Xie, M;Maifoshie, E;Jenkins, M;Golforoush, PA;Bellahcene, M;Noseda, M;Faust, D;Jarvis, A;Newton, G;Paiva, MA;Harada, M;Stuckey, DJ;Song, W;Habib, J;Narasimham, P;Aqil, R;Sanmugalingam, D;Yan, R;Pavanello, L;Sano, M;Wang, SC;Sampson, RD;Kanayaganam, S;Taffet, GE;Michael, LH;Entman, ML;Tan, TH;Harding, SE;Low, CMR;Tralau-Stewart, C;Perrior, T;Schneider, MD
國家衛生研究院 2018-2018 MAP4K3 (GLK) Chuang, HC;Tan, TH
國家衛生研究院 2018-12 RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell Lin, JC;Lee, YC;Tan, TH;Liang, YC;Chuang, HC;Fann, YC;Johnson, KR;Lin, YJ
國家衛生研究院 2018-09-20 PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency Chen, MY;Hsu, WC;Hsu, SC;Yang, YS;Chuang, TH;Lin, WJ;Tan, TH;Su, YW
國家衛生研究院 2018-09-12 GLK-IKKbeta signaling induces dimerization and translocation of the AhR-RORgammat complex in IL-17A induction and autoimmune disease Chuang, HC;Tsai, CY;Hsueh, CH;Tan, TH
國家衛生研究院 2018-09-06 RBM4A-SRSF3-MAP4K4 splicing cascade constitutes a molecular mechanism for regulating brown adipogenesis Peng, HY;Liang, YC;Tan, TH;Chuang, HC;Lin, YJ;Lin, JC
國家衛生研究院 2018-08-21 DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation Hsu, WC;Chen, MY;Hsu, SC;Huang, LR;Kao, CY;Cheng, WH;Pan, CH;Wu, MS;Yu, GY;Hung, MS;Leu, CM;Tan, TH;Su, YW
國家衛生研究院 2018-06-19 Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation Yang, CY;Chiu, LL;Chang, CC;Chuang, HC;Tan, TH
國家衛生研究院 2017-11 Deficiency in VHR/DUSP3, a suppressor of focal adhesion kinase, reveals its role in regulating cell adhesion and migration Chen, YR;Chou, HC;Yang, CH;Chen, HY;Liu, YW;Lin, TY;Yeh, CL;Chao, WT;Tsou, HH;Chuang, HC;Tan, TH
國家衛生研究院 2017-07-19 MAP4k3 as a biomarker and therapetic target for autoimmune disease, cancer, inflammation and il-17- associated disease Tan, TH;Chuang, HC
國家衛生研究院 2017-02 Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice Ruan, JW;Statt, S;Huang, CT;Tsai, YT;Kuo, CC;Chan, HL;Liao, YC;Tan, TH;Kao, CY
國家衛生研究院 2017-01-07 MAP4K4 and IL-6+ Th17 cells play important roles in non-obese type 2 diabetes Chuang, HC;Tan, TH
國家衛生研究院 2016-08 Downregulation of the phosphatase JKAP/DUSP22 in T Cells as a potential new biomarker of systemic lupus erythematosus nephritis Chuang, HC;Chen, YM;Hung, WT;Li, JP;Chen, DY;Lan, JL;Tan, TH
國家衛生研究院 2016-08 Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses Chen, KR;Yang, CY;Lin, CY;Lin, WY;Lo, YC;Chuang, HC;Tan, TH;Ling, P
國家衛生研究院 2016-08 Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond Ling, P;Chen, KR;Kao, CC;Chuang, HC;Tan, TH
國家衛生研究院 2016-08 Serine/threonine phosphatase PP4 is required for class switch recombination through recruitment of gammaH2AX Chen, MY;Chen, YP;Tan, TH;Su, YW
國家衛生研究院 2016-08 Molecular mechanisms of DUSP22 ablation in enhancing EGFR-mediated lung tumor development: Potential involvement of immunosuppression Lin, HP;Ho, HM;Chang, CW;Tan, TH;Lin, WJ
國家衛生研究院 2016-08 HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to T-cell-mediated type 2 diabetes Chuang, HC;Tan, TH
國家衛生研究院 2016-07 GLK/MAP4K3 overexpression associates with recurrence risk for non-small cell lung cancer Hsu, CP;Chuang, HC;Lee, MC;Tsou, HH;Lee, LW;Li, JP;Tan, TH
國家衛生研究院 2016-07 Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase Ho, CH;Chuang, HC;Wu, IC;Tsai, HW;Lin, YJ;Sun, HY;Young, KC;Chiu, YC;Cheng, PN;Liu, WC;Tan, TH;Chang, TT
國家衛生研究院 2016-05 A multi-prong global study provides insights to gut microbiota and mucosal immunity in dusp6-deficiency conferred obesity-resistance Ruan, JW;Statt, S;Huang, CT;Tsai, YT;Chan, HL;Tan, TH;Kao, CY
國家衛生研究院 2016-05 Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses Chen, KR;Yang, CY;Lin, CY;Lin, WY;Lo, YC;Chuang, HC;Tan, TH;Ling, P
國家衛生研究院 2016-05 Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond Ling, P;Cheni, KR;Kao, CC;Chuang, HC;Tan, TH
國家衛生研究院 2016-03-08 Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients Chuang, HC;Wang, JS;Lee, IT;Sheu, WH;Tan, TH

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