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Showing items 11-60 of 132 (3 Page(s) Totally)
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Institution	Date	Title	Author
臺大學術典藏	2022-03-14T12:48:31Z	Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435	Ruchelman A.L.; Singh S.K.; Wu X.; Ray A.; Yang J.-M.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:31Z	2,3-Dimethoxybenzo[i]phenanthridines: Topoisomerase I-targeting anticancer agents	Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:31Z	Human topoisomerase I poisoning by protoberberines: Potential roles for both drug-DNA and drug-enzyme interactions	TSAI-KUN LI; Bathory E.; LaVoie E.J.; Srinivasan A.R.; Olson W.K.; Sauers R.R.; Liu L.F.; Pilch D.S.
臺大學術典藏	2022-03-14T12:48:31Z	Ubiquitin/26s proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells	Desai S.D.; TSAI-KUN LI; Rodriguez-Bauman A.; Liu L.F.; Rubin E.H.
臺大學術典藏	2022-03-14T12:48:31Z	Tumor cell death induced by topoisomerase-targeting drugs	TSAI-KUN LI; Liu L.F.
臺大學術典藏	2022-03-14T12:48:30Z	Acidic pH induces topoisomerase II-mediated DNA damage	Xiao H.; TSAI-KUN LI; Yang J.-M.; Liu L.F.
臺大學術典藏	2022-03-14T12:48:30Z	Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast	Qi H.; TSAI-KUN LI; Kuo D.; Nur-E-Kamal A.; Liu L.F.
臺大學術典藏	2022-03-14T12:48:30Z	Substituted dibenzo[c,h]cinnolines: Topoisomerase I-targeting anticancer agents	Yu Y.; Singh S.K.; Liu A.; TSAI-KUN LI; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:30Z	Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals	Nur-E-Kamal A.; TSAI-KUN LI; Zhang A.; Qi H.; Hars E.S.; Liu L.F.
臺大學術典藏	2022-03-14T12:48:30Z	Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents	Makhey D.; Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:29Z	DNA damage-mediated apoptosis induced by selenium compounds	Zhou N.; Xiao H.; TSAI-KUN LI; Nur-E-Kamal A.; Liu L.F.
臺大學術典藏	2022-03-14T12:48:29Z	Aminoglycoside complexation with a DNA·RNA hybrid duplex: The thermodynamics of recognition and inhibition of RNA processing enzymes	Barbieri C.M.; TSAI-KUN LI; Guo S.; Wang G.; Shallop A.J.; Pan W.; Yang G.; Gaffney B.L.; Jones R.A.; Pilch D.S.
臺大學術典藏	2022-03-14T12:48:29Z	Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)2,3-methylenedioxy-5H-dibenzo[c,h][1,6] naphthyridin-6-ones: Effect on topoisomerase-I targeting activity and cytotoxicity	Singh S.K.; Ruchelman A.L.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:29Z	5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity	Ruchelman A.L.; Singh S.K.; Ray A.; Wu X.H.; Yang J.-M.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:28Z	Aza-analogs of dibenzo[c,h]cinnoline: Triazachrysenes as potent topoisomerase I-targeting anticancer agents	Singh S.K.; Ruchelman A.L.; Zhou N.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:28Z	8,9-Methylenedioxybenzo[i]phenanthridines: Topoisomerase I-targeting activity and cytotoxicity	Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:28Z	Hydrogen Peroxide Induces Topoisomerase I-mediated DNA Damage and Cell Death	Daroui P.; Desai S.D.; TSAI-KUN LI; Liu A.A.; Liu L.F.
臺大學術典藏	2022-03-14T12:48:28Z	Characterization of ARC-111 as a Novel Topoisomerase I-Targeting Anticancer Drug	TSAI-KUN LI; Houghton P.J.; Desai S.D.; Daroui P.; Liu A.A.; Hars E.S.; Ruchelman A.L.; LaVoie E.J.; Liu L.F.
臺大學術典藏	2022-03-14T12:48:27Z	Involvement of topoisomerase III in telomere-telomere recombination	Tsai H.-J.; Huang W.-H.; TSAI-KUN LI; Tsai Y.-L.; Wu K.-J.; Tseng S.-F.; Teng S.-C.
臺大學術典藏	2022-03-14T12:48:27Z	Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N, N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Influence on topoisomerase I-targeting activity and cytotoxicity	Ruchelman A.L.; Kerrigan J.E.; TSAI-KUN LI; Zhou N.; Liu A.; Liu L.F.; LaVoie E.J.
臺大學術典藏	2022-03-14T12:48:27Z	Drug targeting of HIV-1 RNA·DNA hybrid structures: Thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication	TSAI-KUN LI; Barbieri C.M.; Lin H.-C.; Rabson A.B.; Yang G.; Fan Y.; Gaffney B.L.; Jones R.A.; Pilch D.S.
臺大學術典藏	2022-03-14T12:48:26Z	Distribution of gyrase and topoisomerase IV on bacterial nucleoid: Implications for nucleoid organization	Hsu Y.-H.; Chung M.-W.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:26Z	Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells	Chiang P.-C.; Kung F.-L.; Huang D.-M.; TSAI-KUN LI; Fan J.-R.; Pan S.-L.; Shen Y.-C.; Guh J.-H.
臺大學術典藏	2022-03-14T12:48:26Z	Prazosin displays anticancer activity against human prostate cancers: Targeting DNA and cell cycle	Lin S.-C.; Chueh S.-C.; Hsiao C.-J.; TSAI-KUN LI; Chen T.-H.; Liao C.-H.; Lyu P.-C.; Guh J.-H.
臺大學術典藏	2022-03-14T12:48:26Z	Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication	Lu C.-C.; Huang H.-T.; Wang J.-T.; Slupphaug G.; TSAI-KUN LI; Wu M.-C.; Chen Y.-C.; Lee C.-P.; Chen M.-R.
臺大學術典藏	2022-03-14T12:48:25Z	Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates	Hsin L.-W.; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; Guh J.-H.; Chan Y.-L.; His C.-P.; Yang M.-S.; TSAI-KUN LI; Lee C.-H.
臺大學術典藏	2022-03-14T12:48:25Z	Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult	Yeh T.-C.; Chiang P.-C.; TSAI-KUN LI; Hsu J.-L.; Lin C.-J.; Wang S.-W.; Peng C.-Y.; Guh J.-H.
臺大學術典藏	2022-03-14T12:48:24Z	Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses	Fan J.-R.; Peng A.-L.; Chen H.-C.; Lo S.-C.; Huang T.-H.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:24Z	WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers	Hsiao C.-J.; TSAI-KUN LI; Chan Y.-L.; Hsin L.-W.; Liao C.-H.; Lee C.-H.; Lyu P.-C.; Guh J.-H.
臺大學術典藏	2022-03-14T12:48:24Z	Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism	Tai C.C.; Chen C.Y.; Lee H.S.; Wang Y.C.; TSAI-KUN LI; Mersamm H.J.; Ding S.T.; Wang P.H.
臺大學術典藏	2022-03-14T12:48:24Z	Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification	You Q.-D.; Li Z.-Y.; Huang C.-H.; Yang Q.; Wang X.-J.; Guo Q.-L.; Chen X.-G.; He X.-G.; TSAI-KUN LI; Chern J.-W.
臺大學術典藏	2022-03-14T12:48:23Z	Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage	Huang T.-H.; Chen H.-C.; Chou S.-M.; Yang Y.-C.; Fan J.-R.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:23Z	EGF-induced Grb7 recruits and promotes ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells	Chu P.-Y.; TSAI-KUN LI; Ding S.-T.; Lai I.-R.; Shen T.-L.
臺大學術典藏	2022-03-14T12:48:23Z	Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide	Wu C.-C.; TSAI-KUN LI; Farh L.; Lin L.-Y.; Lin T.-S.; Yu Y.-J.; Yen T.-J.; Chiang C.-W.; Chan N.-L.
臺大學術典藏	2022-03-14T12:48:23Z	Sodium salicylate acts through direct inhibition of phosphoinositide 3-kinase-like kinases to modulate topoisomerase-mediated DNA damage responses	Fan J.-R.; Huang T.-H.; Wen C.-Y.; Shen T.-L.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:22Z	Mitoxantrone inhibits HIF-1α expression in a topoisomerase II-independent pathway	Toh Y.-M.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:22Z	QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells	Chen M.-C.; Pan S.-L.; Shi Q.; Xiao Z.; Lee K.-H.; TSAI-KUN LI; Teng C.-M.
臺大學術典藏	2022-03-14T12:48:22Z	Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2	Chou S.-M.; Huang T.-H.; Chen H.-C.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:21Z	Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway	Hsu J.-L.; Ho Y.-F.; TSAI-KUN LI; Chen C.-S.; Hsu L.-C.; Guh J.-H.
臺大學術典藏	2022-03-14T12:48:21Z	Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles	Lee C.-H.; Hsieh M.-Y.; Hsin L.-W.; Chen H.-C.; Lo S.-C.; Fan J.-R.; Chen W.-R.; Chen H.-W.; Chan N.-L.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:21Z	Multiple domains of the Tobacco mosaic virus p126 protein can independently suppress local and systemic RNA silencing	Wang L.-Y.; Lin S.-S.; Hung T.-H.; TSAI-KUN LI; Lin N.-C.; Shen T.-L.
臺大學術典藏	2022-03-14T12:48:21Z	Cell type-specific effects of Adenosine 5′-triphosphate and pyrophosphate on the antitumor activity of doxorubicin	Wang J.-S.; Chang Y.-L.; Yu Y.-H.; Chen C.-Y.; Kao M.-C.; TSAI-KUN LI; Lin W.-W.
臺大學術典藏	2022-03-14T12:48:20Z	Topoisomerase II-mediated DNA cleavage and mutagenesis activated by nitric oxide underlie the inflammation-associated tumorigenesis	Yang Y.-C.; Chou H.-Y.E.; Shen T.-L.; Chang W.-J.; Tai P.-H.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:20Z	DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia	Lin B.-C.; Su L.-H.; Weng S.-C.; Pan Y.-J.; Chan N.-L.; TSAI-KUN LI; Wang H.-C.; Sun C.-H.
臺大學術典藏	2022-03-14T12:48:20Z	Docosahexaenoic acid suppresses the expression of FoxO and its target genes	Chen Y.-J.; Chen C.-C.; TSAI-KUN LI; Wang P.-H.; Liu L.-R.; Chang F.-Y.; Wang Y.-C.; Yu Y.-H.; Lin S.-P.; Mersmann H.J.; Ding S.-T.
臺大學術典藏	2022-03-14T12:48:19Z	A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i	Yu C.-C.; Pan S.-L.; Chao S.-W.; Liu S.-P.; Hsu J.-L.; Yang Y.-C.; TSAI-KUN LI; Huang W.-J.; Guh J.-H.
臺大學術典藏	2022-03-14T12:48:19Z	On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs	Wu C.-C.; Li Y.-C.; Wang Y.-R.; TSAI-KUN LI; Chan N.-L.
臺大學術典藏	2022-03-14T12:48:19Z	DNA topoisomerase III alpha regulates P53-mediated tumor suppression	Hsieh M.-Y.; Fan J.-R.; Chang H.-W.; Chen H.-C.; Shen T.-L.; Teng S.-C.; Yeh Y.-H.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:19Z	A negative feedback of the HIF-1α pathway via interferon-stimulated gene 15 and ISGylation	Yeh Y.-H.; Yang Y.-C.; Hsieh M.-Y.; Yeh Y.-C.; TSAI-KUN LI
臺大學術典藏	2022-03-14T12:48:18Z	Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential	Wang Y.-W.; Hong T.-W.; Tai Y.-L.; Wang Y.-J.; Tsai S.-H.; Lien P.T.K.; Chou T.-H.; Lai J.-Y.; Chu R.; Ding S.-T.; Irie K.; TSAI-KUN LI; Tzean S.-S.; Shen T.-L.

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