| 臺大學術典藏 |
2022-03-14T12:48:34Z |
Cellular resistance to topoisomerase poisons.
|
Rubin E.H.; TSAI-KUN LI; Duann P.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:33Z |
Selective cytotoxicity of topoisomerase-directed protoberberines against glioblastoma cells
|
Sanders M.M.; Liu A.A.; TSAI-KUN LI; Wu H.-Y.; Desai S.D.; Mao Y.; Rubin E.H.; LaVoie E.J.; Makhey D.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:33Z |
DNA minor groove binding-directed poisoning of human DNA topoisomerase I by terbenzimidazoles
|
Xu Z.; TSAI-KUN LI; Kim J.S.; LaVoie E.J.; Breslauer K.J.; Liu L.F.; Pilch D.S. |
| 臺大學術典藏 |
2022-03-14T12:48:33Z |
Differential poisoning of topoisomerases by menogaril and nogalamycin dictated by the minor groove-binding nogalose sugar
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Sim S.-P.; Gatto B.; Yu C.; Liu A.A.; TSAI-KUN LI; Pilch D.S.; LaVoie E.J.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:33Z |
Modulation of gyrase-mediated DNA cleavage and cell killing by ATP
|
TSAI-KUN LI; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:33Z |
Incompatibility of Escherichia coli rho mutants with plasmids is mediated by plasmid-specific transcription
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TSAI-KUN LI; Panchenko Y.A.; Drolet M.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:32Z |
Ubiquitin, SUMO-1, and UCRP in camptothesin sensitivity and resistance
|
Desai S.D.; Yong M.A.O.; Sun M.E.I.; TSAI-KUN LI; Jiaxi W.U.; Liu L.F.; New Jersey |
| 臺大學術典藏 |
2022-03-14T12:48:32Z |
The camptothecins: Unfolding their anticancer potential: Introduction
|
Liu L.F.; Desai S.D.; TSAI-KUN LI; Yong M.A.O.; Sun M.E.I.; Sai-Peng S.I.M. |
| 臺大學術典藏 |
2022-03-14T12:48:32Z |
Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress
|
TSAI-KUN LI; Chen A.Y.; Yu C.; Mao Y.; Wang H.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:32Z |
Mechanism of action of camptothecin
|
Liu L.F.; Desai S.D.; TSAI-KUN LI; Mao Y.; Sun M.; Sim S.-P. |
| 臺大學術典藏 |
2022-03-14T12:48:31Z |
Diaza- and triazachrysenes: Potent topoisomerase-targeting agents with exceptional antitumor activity against the human tumor xenograft, MDA-MB-435
|
Ruchelman A.L.; Singh S.K.; Wu X.; Ray A.; Yang J.-M.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:31Z |
2,3-Dimethoxybenzo[i]phenanthridines: Topoisomerase I-targeting anticancer agents
|
Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:31Z |
Human topoisomerase I poisoning by protoberberines: Potential roles for both drug-DNA and drug-enzyme interactions
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TSAI-KUN LI; Bathory E.; LaVoie E.J.; Srinivasan A.R.; Olson W.K.; Sauers R.R.; Liu L.F.; Pilch D.S. |
| 臺大學術典藏 |
2022-03-14T12:48:31Z |
Ubiquitin/26s proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells
|
Desai S.D.; TSAI-KUN LI; Rodriguez-Bauman A.; Liu L.F.; Rubin E.H. |
| 臺大學術典藏 |
2022-03-14T12:48:31Z |
Tumor cell death induced by topoisomerase-targeting drugs
|
TSAI-KUN LI; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:30Z |
Acidic pH induces topoisomerase II-mediated DNA damage
|
Xiao H.; TSAI-KUN LI; Yang J.-M.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:30Z |
Inactivation of Cdc13p triggers MEC1-dependent apoptotic signals in yeast
|
Qi H.; TSAI-KUN LI; Kuo D.; Nur-E-Kamal A.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:30Z |
Substituted dibenzo[c,h]cinnolines: Topoisomerase I-targeting anticancer agents
|
Yu Y.; Singh S.K.; Liu A.; TSAI-KUN LI; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:30Z |
Single-stranded DNA induces ataxia telangiectasia mutant (ATM)/p53-dependent DNA damage and apoptotic signals
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Nur-E-Kamal A.; TSAI-KUN LI; Zhang A.; Qi H.; Hars E.S.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:30Z |
Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents
|
Makhey D.; Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:29Z |
DNA damage-mediated apoptosis induced by selenium compounds
|
Zhou N.; Xiao H.; TSAI-KUN LI; Nur-E-Kamal A.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:29Z |
Aminoglycoside complexation with a DNA·RNA hybrid duplex: The thermodynamics of recognition and inhibition of RNA processing enzymes
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Barbieri C.M.; TSAI-KUN LI; Guo S.; Wang G.; Shallop A.J.; Pan W.; Yang G.; Gaffney B.L.; Jones R.A.; Pilch D.S. |
| 臺大學術典藏 |
2022-03-14T12:48:29Z |
Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)2,3-methylenedioxy-5H-dibenzo[c,h][1,6] naphthyridin-6-ones: Effect on topoisomerase-I targeting activity and cytotoxicity
|
Singh S.K.; Ruchelman A.L.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:29Z |
5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity
|
Ruchelman A.L.; Singh S.K.; Ray A.; Wu X.H.; Yang J.-M.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:28Z |
Aza-analogs of dibenzo[c,h]cinnoline: Triazachrysenes as potent topoisomerase I-targeting anticancer agents
|
Singh S.K.; Ruchelman A.L.; Zhou N.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:28Z |
8,9-Methylenedioxybenzo[i]phenanthridines: Topoisomerase I-targeting activity and cytotoxicity
|
Li D.; Zhao B.; Sim S.-P.; TSAI-KUN LI; Liu A.; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:28Z |
Hydrogen Peroxide Induces Topoisomerase I-mediated DNA Damage and Cell Death
|
Daroui P.; Desai S.D.; TSAI-KUN LI; Liu A.A.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:28Z |
Characterization of ARC-111 as a Novel Topoisomerase I-Targeting Anticancer Drug
|
TSAI-KUN LI; Houghton P.J.; Desai S.D.; Daroui P.; Liu A.A.; Hars E.S.; Ruchelman A.L.; LaVoie E.J.; Liu L.F. |
| 臺大學術典藏 |
2022-03-14T12:48:27Z |
Involvement of topoisomerase III in telomere-telomere recombination
|
Tsai H.-J.; Huang W.-H.; TSAI-KUN LI; Tsai Y.-L.; Wu K.-J.; Tseng S.-F.; Teng S.-C. |
| 臺大學術典藏 |
2022-03-14T12:48:27Z |
Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N, N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: Influence on topoisomerase I-targeting activity and cytotoxicity
|
Ruchelman A.L.; Kerrigan J.E.; TSAI-KUN LI; Zhou N.; Liu A.; Liu L.F.; LaVoie E.J. |
| 臺大學術典藏 |
2022-03-14T12:48:27Z |
Drug targeting of HIV-1 RNA·DNA hybrid structures: Thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication
|
TSAI-KUN LI; Barbieri C.M.; Lin H.-C.; Rabson A.B.; Yang G.; Fan Y.; Gaffney B.L.; Jones R.A.; Pilch D.S. |
| 臺大學術典藏 |
2022-03-14T12:48:26Z |
Distribution of gyrase and topoisomerase IV on bacterial nucleoid: Implications for nucleoid organization
|
Hsu Y.-H.; Chung M.-W.; TSAI-KUN LI |
| 臺大學術典藏 |
2022-03-14T12:48:26Z |
Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells
|
Chiang P.-C.; Kung F.-L.; Huang D.-M.; TSAI-KUN LI; Fan J.-R.; Pan S.-L.; Shen Y.-C.; Guh J.-H. |
| 臺大學術典藏 |
2022-03-14T12:48:26Z |
Prazosin displays anticancer activity against human prostate cancers: Targeting DNA and cell cycle
|
Lin S.-C.; Chueh S.-C.; Hsiao C.-J.; TSAI-KUN LI; Chen T.-H.; Liao C.-H.; Lyu P.-C.; Guh J.-H. |
| 臺大學術典藏 |
2022-03-14T12:48:26Z |
Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication
|
Lu C.-C.; Huang H.-T.; Wang J.-T.; Slupphaug G.; TSAI-KUN LI; Wu M.-C.; Chen Y.-C.; Lee C.-P.; Chen M.-R. |
| 臺大學術典藏 |
2022-03-14T12:48:25Z |
Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates
|
Hsin L.-W.; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; Guh J.-H.; Chan Y.-L.; His C.-P.; Yang M.-S.; TSAI-KUN LI; Lee C.-H. |
| 臺大學術典藏 |
2022-03-14T12:48:25Z |
Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult
|
Yeh T.-C.; Chiang P.-C.; TSAI-KUN LI; Hsu J.-L.; Lin C.-J.; Wang S.-W.; Peng C.-Y.; Guh J.-H. |
| 臺大學術典藏 |
2022-03-14T12:48:24Z |
Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses
|
Fan J.-R.; Peng A.-L.; Chen H.-C.; Lo S.-C.; Huang T.-H.; TSAI-KUN LI |
| 臺大學術典藏 |
2022-03-14T12:48:24Z |
WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers
|
Hsiao C.-J.; TSAI-KUN LI; Chan Y.-L.; Hsin L.-W.; Liao C.-H.; Lee C.-H.; Lyu P.-C.; Guh J.-H. |
| 臺大學術典藏 |
2022-03-14T12:48:24Z |
Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism
|
Tai C.C.; Chen C.Y.; Lee H.S.; Wang Y.C.; TSAI-KUN LI; Mersamm H.J.; Ding S.T.; Wang P.H. |
| 臺大學術典藏 |
2022-03-14T12:48:24Z |
Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification
|
You Q.-D.; Li Z.-Y.; Huang C.-H.; Yang Q.; Wang X.-J.; Guo Q.-L.; Chen X.-G.; He X.-G.; TSAI-KUN LI; Chern J.-W. |
| 臺大學術典藏 |
2022-03-14T12:48:23Z |
Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage
|
Huang T.-H.; Chen H.-C.; Chou S.-M.; Yang Y.-C.; Fan J.-R.; TSAI-KUN LI |
| 臺大學術典藏 |
2022-03-14T12:48:23Z |
EGF-induced Grb7 recruits and promotes ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells
|
Chu P.-Y.; TSAI-KUN LI; Ding S.-T.; Lai I.-R.; Shen T.-L. |
| 臺大學術典藏 |
2022-03-14T12:48:23Z |
Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide
|
Wu C.-C.; TSAI-KUN LI; Farh L.; Lin L.-Y.; Lin T.-S.; Yu Y.-J.; Yen T.-J.; Chiang C.-W.; Chan N.-L. |
| 臺大學術典藏 |
2022-03-14T12:48:23Z |
Sodium salicylate acts through direct inhibition of phosphoinositide 3-kinase-like kinases to modulate topoisomerase-mediated DNA damage responses
|
Fan J.-R.; Huang T.-H.; Wen C.-Y.; Shen T.-L.; TSAI-KUN LI |
| 臺大學術典藏 |
2022-03-14T12:48:22Z |
Mitoxantrone inhibits HIF-1α expression in a topoisomerase II-independent pathway
|
Toh Y.-M.; TSAI-KUN LI |
| 臺大學術典藏 |
2022-03-14T12:48:22Z |
QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells
|
Chen M.-C.; Pan S.-L.; Shi Q.; Xiao Z.; Lee K.-H.; TSAI-KUN LI; Teng C.-M. |
| 臺大學術典藏 |
2022-03-14T12:48:22Z |
Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2
|
Chou S.-M.; Huang T.-H.; Chen H.-C.; TSAI-KUN LI |
| 臺大學術典藏 |
2022-03-14T12:48:21Z |
Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway
|
Hsu J.-L.; Ho Y.-F.; TSAI-KUN LI; Chen C.-S.; Hsu L.-C.; Guh J.-H. |
| 臺大學術典藏 |
2022-03-14T12:48:21Z |
Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles
|
Lee C.-H.; Hsieh M.-Y.; Hsin L.-W.; Chen H.-C.; Lo S.-C.; Fan J.-R.; Chen W.-R.; Chen H.-W.; Chan N.-L.; TSAI-KUN LI |
