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機構 日期 題名 作者
臺大學術典藏 2022-03-14T12:48:25Z Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates Hsin L.-W.; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; Guh J.-H.; Chan Y.-L.; His C.-P.; Yang M.-S.; TSAI-KUN LI; Lee C.-H.
臺大學術典藏 2022-03-14T12:48:25Z Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult Yeh T.-C.; Chiang P.-C.; TSAI-KUN LI; Hsu J.-L.; Lin C.-J.; Wang S.-W.; Peng C.-Y.; Guh J.-H.
臺大學術典藏 2022-03-14T12:48:24Z Cellular processing pathways contribute to the activation of etoposide-induced DNA damage responses Fan J.-R.; Peng A.-L.; Chen H.-C.; Lo S.-C.; Huang T.-H.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:24Z WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers Hsiao C.-J.; TSAI-KUN LI; Chan Y.-L.; Hsin L.-W.; Liao C.-H.; Lee C.-H.; Lyu P.-C.; Guh J.-H.
臺大學術典藏 2022-03-14T12:48:24Z Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism Tai C.C.; Chen C.Y.; Lee H.S.; Wang Y.C.; TSAI-KUN LI; Mersamm H.J.; Ding S.T.; Wang P.H.
臺大學術典藏 2022-03-14T12:48:24Z Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification You Q.-D.; Li Z.-Y.; Huang C.-H.; Yang Q.; Wang X.-J.; Guo Q.-L.; Chen X.-G.; He X.-G.; TSAI-KUN LI; Chern J.-W.
臺大學術典藏 2022-03-14T12:48:23Z Cellular processing determinants for the activation of damage signals in response to topoisomerase I-linked DNA breakage Huang T.-H.; Chen H.-C.; Chou S.-M.; Yang Y.-C.; Fan J.-R.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:23Z EGF-induced Grb7 recruits and promotes ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells Chu P.-Y.; TSAI-KUN LI; Ding S.-T.; Lai I.-R.; Shen T.-L.
臺大學術典藏 2022-03-14T12:48:23Z Structural basis of type II topoisomerase inhibition by the anticancer drug etoposide Wu C.-C.; TSAI-KUN LI; Farh L.; Lin L.-Y.; Lin T.-S.; Yu Y.-J.; Yen T.-J.; Chiang C.-W.; Chan N.-L.
臺大學術典藏 2022-03-14T12:48:23Z Sodium salicylate acts through direct inhibition of phosphoinositide 3-kinase-like kinases to modulate topoisomerase-mediated DNA damage responses Fan J.-R.; Huang T.-H.; Wen C.-Y.; Shen T.-L.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:22Z Mitoxantrone inhibits HIF-1α expression in a topoisomerase II-independent pathway Toh Y.-M.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:22Z QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells Chen M.-C.; Pan S.-L.; Shi Q.; Xiao Z.; Lee K.-H.; TSAI-KUN LI; Teng C.-M.
臺大學術典藏 2022-03-14T12:48:22Z Calcium-induced cleavage of DNA topoisomerase I involves the cytoplasmic-nuclear shuttling of calpain 2 Chou S.-M.; Huang T.-H.; Chen H.-C.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:21Z Rottlerin potentiates camptothecin-induced cytotoxicity in human hormone refractory prostate cancers through increased formation and stabilization of topoisomerase I-DNA cleavage complexes in a PKCδ-independent pathway Hsu J.-L.; Ho Y.-F.; TSAI-KUN LI; Chen C.-S.; Hsu L.-C.; Guh J.-H.
臺大學術典藏 2022-03-14T12:48:21Z Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles Lee C.-H.; Hsieh M.-Y.; Hsin L.-W.; Chen H.-C.; Lo S.-C.; Fan J.-R.; Chen W.-R.; Chen H.-W.; Chan N.-L.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:21Z Multiple domains of the Tobacco mosaic virus p126 protein can independently suppress local and systemic RNA silencing Wang L.-Y.; Lin S.-S.; Hung T.-H.; TSAI-KUN LI; Lin N.-C.; Shen T.-L.
臺大學術典藏 2022-03-14T12:48:21Z Cell type-specific effects of Adenosine 5′-triphosphate and pyrophosphate on the antitumor activity of doxorubicin Wang J.-S.; Chang Y.-L.; Yu Y.-H.; Chen C.-Y.; Kao M.-C.; TSAI-KUN LI; Lin W.-W.
臺大學術典藏 2022-03-14T12:48:20Z Topoisomerase II-mediated DNA cleavage and mutagenesis activated by nitric oxide underlie the inflammation-associated tumorigenesis Yang Y.-C.; Chou H.-Y.E.; Shen T.-L.; Chang W.-J.; Tai P.-H.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:20Z DNA Topoisomerase II Is Involved in Regulation of Cyst Wall Protein Genes and Differentiation in Giardia lamblia Lin B.-C.; Su L.-H.; Weng S.-C.; Pan Y.-J.; Chan N.-L.; TSAI-KUN LI; Wang H.-C.; Sun C.-H.
臺大學術典藏 2022-03-14T12:48:20Z Docosahexaenoic acid suppresses the expression of FoxO and its target genes Chen Y.-J.; Chen C.-C.; TSAI-KUN LI; Wang P.-H.; Liu L.-R.; Chang F.-Y.; Wang Y.-C.; Yu Y.-H.; Lin S.-P.; Mersmann H.J.; Ding S.-T.
臺大學術典藏 2022-03-14T12:48:19Z A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i Yu C.-C.; Pan S.-L.; Chao S.-W.; Liu S.-P.; Hsu J.-L.; Yang Y.-C.; TSAI-KUN LI; Huang W.-J.; Guh J.-H.
臺大學術典藏 2022-03-14T12:48:19Z On the structural basis and design guidelines for type II topoisomerase-targeting anticancer drugs Wu C.-C.; Li Y.-C.; Wang Y.-R.; TSAI-KUN LI; Chan N.-L.
臺大學術典藏 2022-03-14T12:48:19Z DNA topoisomerase III alpha regulates P53-mediated tumor suppression Hsieh M.-Y.; Fan J.-R.; Chang H.-W.; Chen H.-C.; Shen T.-L.; Teng S.-C.; Yeh Y.-H.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:19Z A negative feedback of the HIF-1α pathway via interferon-stimulated gene 15 and ISGylation Yeh Y.-H.; Yang Y.-C.; Hsieh M.-Y.; Yeh Y.-C.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:18Z Evaluation of an Epitypified Ophiocordyceps formosana (Cordyceps s.l.) for Its Pharmacological Potential Wang Y.-W.; Hong T.-W.; Tai Y.-L.; Wang Y.-J.; Tsai S.-H.; Lien P.T.K.; Chou T.-H.; Lai J.-Y.; Chu R.; Ding S.-T.; Irie K.; TSAI-KUN LI; Tzean S.-S.; Shen T.-L.
臺大學術典藏 2022-03-14T12:48:18Z Synergistic property of cordycepin in cultivated Cordyceps militaris-mediated apoptosis in human leukemia cells Chou S.-M.; Lai W.-J.; Hong T.-W.; Lai J.-Y.; Tsai S.-H.; Chen Y.-H.; Yu S.-H.; Kao C.-H.; Chu R.; Ding S.-T.; TSAI-KUN LI; Shen T.-L.
臺大學術典藏 2022-03-14T12:48:18Z Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers Hsieh M.-H.; Tsai C.-H.; Lin C.-C.; TSAI-KUN LI; Hung T.-W.; Chang L.-T.; Hsin L.-W.; Teng S.-C.
臺大學術典藏 2022-03-14T12:48:17Z Rhapontigenin inhibits TGF-β-mediated epithelial-mesenchymal transition via the PI3K/AKT/mTOR pathway and is not associated with HIF-1α degradation Yeh Y.-H.; Wang S.-W.; Yeh Y.-C.; Hsiao H.-F.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:17Z Involvement of p38 MAPK in the anticancer activity of cultivated cordyceps militaris Chou S.-M.; Lai W.-J.; Hong T.; Tsai S.-H.; Chen Y.-H.; Kao C.-H.; Chu R.; Shen T.-L.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:17Z Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts Chien M.-H.; Lee T.-H.; Lee W.-J.; Yeh Y.-H.; TSAI-KUN LI; Wang P.-C.; Chen J.-J.; Chow J.-M.; Lin Y.-W.; Hsiao M.; Wang S.-W.; Hua K.-T.
臺大學術典藏 2022-03-14T12:48:16Z Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway Yeh Y.-H.; Hsiao H.-F.; Yeh Y.-C.; Chen T.-W.; TSAI-KUN LI
臺大學術典藏 2022-03-14T12:48:16Z Regioselective synthesis and biological evaluation of: N -substituted 2-aminoquinazolin-4-ones Liao Z.-Y.; Yeh W.-H.; Liao P.-Y.; Liu Y.-T.; Chen Y.-C.; Chen Y.-H.; Hsieh T.-H.; Lin C.-C.; Lu M.-H.; Chen Y.-S.; Hsu M.-C.; TSAI-KUN LI; Chien T.-C.
臺大學術典藏 2022-03-14T12:48:16Z Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry Wang Y.-R.; Chen S.-F.; Wu C.-C.; Liao Y.-W.; Lin T.-S.; Liu K.-T.; Chen Y.-S.; TSAI-KUN LI; Chien T.-C.; Chan N.-L.
臺大學術典藏 2022-03-14T12:48:16Z MicroRNA-183 Mediates Protective Postconditioning of the Liver by Repressing Apaf-1 Lin H.-C.; Liu S.-Y.; Yen E.-Y.; TSAI-KUN LI; Lai I.-R.
臺大學術典藏 2022-03-14T12:48:15Z Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases Lee J.-F.; Chang T.-Y.; Liu Z.-F.; Lee N.-Z.; Yeh Y.-H.; Chen Y.-S.; Chen T.-C.; Chou H.-S.; TSAI-KUN LI; Lee S.-B.; Lin M.-H.
臺大學術典藏 2022-03-14T12:48:15Z The paracrine induction of prostate cancer progression by caveolin-1 Lin C.-J.; Yun E.-J.; Lo U.-G.; Tai Y.-L.; Deng S.; Hernandez E.; Dang A.; Chen Y.-A.; Saha D.; Mu P.; Lin H.; TSAI-KUN LI; Shen T.-L.; Lai C.-H.; Hsieh J.-T.
臺大學術典藏 2022-03-14T12:48:14Z Retraction notice to “Design, synthesis, and biological evaluation of heterotetracyclic quinolinone derivatives as anticancer agents targeting topoisomerases” [Eur. J. Med. Chem. 190 (2020) 112074] (European Journal of Medicinal Chemistry (2020) 190 (S0223523420300416), (10.1016/j.ejmech.2020.112074)) Lee J.-F.; Chang T.-Y.; Liu Z.-F.; Lee N.-Z.; Yeh Y.-H.; Chen Y.-S.; Chen T.-C.; Chou H.-S.; TSAI-KUN LI; Lee S.-B.; Lin M.-H.
臺大學術典藏 2022-03-14T12:48:14Z Selected ellipticine derivatives, known to target topoisomerase II, suppress the alternative lengthening of telomere (ALT) pathway in telomerase–negative cells Zencir S.; Hsieh M.-H.; Hsu J.-S.; Ergun Y.; Chou G.-L.; TSAI-KUN LI; Teng S.-C.; Topcu Z.
臺大學術典藏 2022-03-14T12:48:14Z The role of extracellular vesicles in prostate cancer with clinical applications Tai Y.-L.; Lin C.-J.; TSAI-KUN LI; Shen T.-L.; Hsieh J.-T.; Chen B.P.C.
臺大學術典藏 2022-03-14T12:48:13Z Activation of multiple proteolysis systems contributes to acute cadmium cytotoxicity Yeh Y.-H.; Tsai C.-C.; Chen T.-W.; Lee C.-H.; Chang W.-J.; Hsieh M.-Y.; TSAI-KUN LI
臺大學術典藏 2022-02-14T23:55:08Z Activation of multiple proteolysis systems contributes to acute cadmium cytotoxicity Yeh, Yen Hsiu; Tsai, Chia Chih; Chen, Tien Wen; Lee, Chieh Hua; Chang, Wei Jer; Hsieh, Mei Yi; TSAI-KUN LI
臺大學術典藏 2019-09-02T05:19:51Z Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway Yeh, Yen-Hsiu;Hsiao, Ho-Fu;Yeh, Yen-Cheng;Chen, Tien-Wen;Tsai-Kun Li; Yeh, Yen-Hsiu; Hsiao, Ho-Fu; Yeh, Yen-Cheng; Chen, Tien-Wen; TSAI-KUN LI
臺大學術典藏 2019-09-02T05:19:51Z Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway Yeh, Yen-Hsiu;Hsiao, Ho-Fu;Yeh, Yen-Cheng;Chen, Tien-Wen;Tsai-Kun Li; Yeh, Yen-Hsiu; Hsiao, Ho-Fu; Yeh, Yen-Cheng; Chen, Tien-Wen; TSAI-KUN LI
臺大學術典藏 2019-09-02T05:18:51Z Regioselective synthesis and biological evaluation of N-substituted 2-aminoquinazolin-4-ones Liao, Zhen-Yuan;Yeh, Wen-Hsiung;Liao, Pen-Yuan;Liu, Yu-Ting;Chen, Ying-Cheng;Chen, Yi-Hung;Hsieh, Tsung-Han;Lin, Chia-Chi;Lu, Ming-Hsuan;Chen, Yi-Song;Hsu, Ming-Chih;Tsai-Kun Li;Chien, Tun-Cheng; Liao, Zhen-Yuan; Yeh, Wen-Hsiung; Liao, Pen-Yuan; Liu, Yu-Ting; Chen, Ying-Cheng; Chen, Yi-Hung; Hsieh, Tsung-Han; Lin, Chia-Chi; Lu, Ming-Hsuan; Chen, Yi-Song; Hsu, Ming-Chih; TSAI-KUN LI; Chien, Tun-Cheng
臺大學術典藏 2019-09-02T05:18:51Z Regioselective synthesis and biological evaluation of N-substituted 2-aminoquinazolin-4-ones Liao, Zhen-Yuan;Yeh, Wen-Hsiung;Liao, Pen-Yuan;Liu, Yu-Ting;Chen, Ying-Cheng;Chen, Yi-Hung;Hsieh, Tsung-Han;Lin, Chia-Chi;Lu, Ming-Hsuan;Chen, Yi-Song;Hsu, Ming-Chih;Tsai-Kun Li;Chien, Tun-Cheng; Liao, Zhen-Yuan; Yeh, Wen-Hsiung; Liao, Pen-Yuan; Liu, Yu-Ting; Chen, Ying-Cheng; Chen, Yi-Hung; Hsieh, Tsung-Han; Lin, Chia-Chi; Lu, Ming-Hsuan; Chen, Yi-Song; Hsu, Ming-Chih; TSAI-KUN LI; Chien, Tun-Cheng
臺大學術典藏 2019-09-02T05:17:53Z Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry Wang, Ying-Ren;Chen, Shin-Fu;Wu, Chyuan-Chuan;Liao, Yi-Wen;Lin, Te-Sheng;Liu, Ko-Ting;Chen, Yi-Song;Tsai-Kun Li;Chien, Tun-Cheng;Nei-Li Chan; Wang, Ying-Ren; Chen, Shin-Fu; Wu, Chyuan-Chuan; Liao, Yi-Wen; Lin, Te-Sheng; Liu, Ko-Ting; Chen, Yi-Song; TSAI-KUN LI; Chien, Tun-Cheng; NEI-LI CHAN
臺大學術典藏 2019-09-02T05:17:53Z Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry Wang, Ying-Ren;Chen, Shin-Fu;Wu, Chyuan-Chuan;Liao, Yi-Wen;Lin, Te-Sheng;Liu, Ko-Ting;Chen, Yi-Song;Tsai-Kun Li;Chien, Tun-Cheng;Nei-Li Chan; Wang, Ying-Ren; Chen, Shin-Fu; Wu, Chyuan-Chuan; Liao, Yi-Wen; Lin, Te-Sheng; Liu, Ko-Ting; Chen, Yi-Song; TSAI-KUN LI; Chien, Tun-Cheng; NEI-LI CHAN
臺大學術典藏 2019-09-02T05:16:14Z Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts KUO-TAI HUA;Wang, Shih-Wei;Hsiao, Michael;Lin, Yung-Wei;Chow, Jyh-Ming;Chen, Jih-Jung;Wang, Po-Chuan;TSAI-KUN LI;Yeh, Yen-Hsiu;Lee, Wei-Jiunn;TZONG-HUEI LEE;Chien, Ming-Hsien; Chien, Ming-Hsien; TZONG-HUEI LEE; Lee, Wei-Jiunn; Yeh, Yen-Hsiu; TSAI-KUN LI; Wang, Po-Chuan; Chen, Jih-Jung; Chow, Jyh-Ming; Lin, Yung-Wei; Hsiao, Michael; Wang, Shih-Wei; KUO-TAI HUA
臺大學術典藏 2019-09-02T05:16:14Z Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts KUO-TAI HUA;Wang, Shih-Wei;Hsiao, Michael;Lin, Yung-Wei;Chow, Jyh-Ming;Chen, Jih-Jung;Wang, Po-Chuan;TSAI-KUN LI;Yeh, Yen-Hsiu;Lee, Wei-Jiunn;TZONG-HUEI LEE;Chien, Ming-Hsien; Chien, Ming-Hsien; TZONG-HUEI LEE; Lee, Wei-Jiunn; Yeh, Yen-Hsiu; TSAI-KUN LI; Wang, Po-Chuan; Chen, Jih-Jung; Chow, Jyh-Ming; Lin, Yung-Wei; Hsiao, Michael; Wang, Shih-Wei; KUO-TAI HUA
臺大學術典藏 2019-09-02T05:10:35Z Cellular resistance to topoisomerase poisons Rubin, E H;Tsai-Kun Li;Duann, P;Liu, L F; Rubin, E H; TSAI-KUN LI; Duann, P; Liu, L F

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