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Showing items 126-169 of 169  (4 Page(s) Totally)
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Institution Date Title Author
國家衛生研究院 2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML Lin, WH;Jiaang, WT;Chen, CW;Yen, KJ;Hsieh, SY;Yen, SC;Chen, CP;Chang, KY;Chang, CY;Chang, TY;Huang, YL;Yeh, TK;Chao, YS;Chen, CT;Hsu, JT
國家衛生研究院 2011-09-27 Formulations of indol-3-yl-2-oxoacetamide compounds Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院 2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells Cheung, CH;Lin, WH;Hsu, TA;Hour, TC;Yeh, TK;Ko, S;Lien, TW;Coumar, MS;Liu, JF;Lai, WY;Shiao, HY;Lee, TR;Hsieh, HP;Chang, JY
國家衛生研究院 2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Lin, WH;Hsieh, SY;Yen, SC;Chen, CT;Yeh, TK;Hsu, T;Lu, CT;Chen, CP;Chen, CW;Chou, LH;Huang, YL;Cheng, AH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Hsu, JT;Jiaang, WT
國家衛生研究院 2011-04-28 Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents Tung, YS;Coumar, MS;Wu, YS;Shiao, HY;Chang, JY;Liou, JP;Shukla, P;Chang, CW;Chang, CY;Kuo, CC;Yeh, TK;Lin, CY;Wu, JS;Wu, SY;Liao, CC;Hsieh, HP
國家衛生研究院 2011-03-27 Design and synthesis of potent Aurora kinase inhibitors Chu, CY;Mohane, CS;Hsu, JTA;Yeh, TK;Chen, CT;Chao, YS;Hsieh, HP
國家衛生研究院 2011-03 Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet Yao, HT;Chiang, MT;Lii, CK;Chang, YW;Hsieh, SH;Lin, JH;Chou, RH;Yeh, TK
國家衛生研究院 2011-03 Potent EGFR tyrosine kinase inhibitors as anticancer agents Shiao, HY;Chu, CY;Hsu, JTA;Yeh, TK;Hsieh, HP
國家衛生研究院 2011-01-13 Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes Yao, CH;Song, JS;Chen, CT;Yeh, TK;Hung, MS;Chang, CC;Liu, YW;Yuan, MC;Hsieh, CJ;Huang, CY;Wang, MH;Chiu, CH;Hsieh, TC;Wu, SH;Hsiao, WC;Chu, KF;Tsai, CH;Chao, YS;Lee, JC
國家衛生研究院 2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities Hu, CB;Chen, CP;Yeh, TK;Song, JS;Chang, CY;Chuu, JJ;Tung, FF;Ho, PY;Chen, TW;Lin, CH;Wang, MH;Chang, KY;Huang, CL;Lin, HL;Li, WT;Hwang, DR;Chern, JH;Hwang, LL;Chang, JY;Chao, YS;Chen, CT
國家衛生研究院 2010-11 Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus Yang, CW;Lee, YZ;Kang, IJ;Barnard, DL;Jan, JT;Lin, D;Huang, CW;Yeh, TK;Chao, YS;Lee, SJ
國家衛生研究院 2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency Wu, CH;Coumar, MS;Chu, CY;Lin, WH;Chen, YR;Chen, CT;Shiao, HY;Rafi, S;Wang, SY;Hsu, H;Chen, CH;Chang, CY;Chang, TY;Lien, TW;Fang, MY;Yeh, KC;Chen, CP;Yeh, TK;Hsieh, SH;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院 2010-10 Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities Lin, Y;Shia, KS;Hsiao, WC;Hsieh, WP;Yeh, TK;Tseng, SL;Hsu, CY;Chao, YS;Hung, MS
國家衛生研究院 2010-09-01 Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors Kang, IJ;Wang, LW;Yeh, TK;Lee, CC;Lee, YC;Hsu, SJ;Wu, YS;Wang, JC;Chao, YS;Yueh, A;Chern, JH
國家衛生研究院 2010-09 Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist Hung, MS;Chang, CP;Li, TC;Yeh, TK;Song, JS;Lin, Y;Wu, CH;Kuo, PC;Amancha, PK;Wong, YC;Hsiao, WC;Chao, YS;Shia, KS
國家衛生研究院 2010-08 Substituted 4-carboxymethylpyroglutamic acid diamides as potent and selective inhibitors of fibroblast activation protein Tsai, TY;Yeh, TK;Chen, X;Hsu, T;Jao, YC;Huang, CH;Song, JS;Huang, YC;Chien, CH;Chiu, JH;Yen, SC;Tang, HK;Chao, YS;Jiaang, WT
國家衛生研究院 2010-07 Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075 Chen, CP;Hu, CB;Yeh, KC;Song, JS;Yeh, TK;Tung, FF;Hwang, LL;Tseng, HY;Huang, YC;Shy, HS;Hsieh, SH;Shen, CC;Wang, HS;Hsieh, HP;Liou, JP;Chao, YS;Chen, CT
國家衛生研究院 2010-06-15 (2S,4S)-1-[2-(1,1-Dimethyl-3-oxo-3-pyrrolidin-1-yl-propylamino)acetyl]-4-fluoro-pyrrolidine-2-carbonitrile: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Yeh, TK;Tsai, TY;Hsu, T;Cheng, JH;Chen, X;Song, JS;Shy, HS;Chiou, MC;Chien, CH;Tseng, YJ;Huang, CY;Yeh, KC;Huang, YL;Huang, CH;Huang, YW;Wang, MH;Tang, HK;Chao, YS;Chen, CT;Jiaang, WT
國家衛生研究院 2010-02 Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91 Yeh, TK;Li, CM;Chen, CP;Chuu, JJ;Huang, CL;Wang, HS;Shen, CC;Lee, TY;Chang, CY;Chang, CM;Chao, YS;Lin, CT;Chang, JY;Chen, CT
國家衛生研究院 2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach Wu, YS;Coumar, MS;Chang, JY;Sun, HY;Kuo, FM;Kuo, CC;Chen, YJ;Chang, CY;Hsiao, CL;Liou, JP;Chen, CP;Yao, HT;Chiang, YK;Tan, UK;Chen, CT;Chu, CY;Wu, SY;Yeh, TK;Lin, CY;Hsieh, HP
中國醫藥大學 2009-08 Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach. (Wu YS); (Coumar MS); (Chang JY); (Sun HY); (Kuo FM); (Kuo CC); (Chen YJ); (Chang CY); (Hsiao CL); (Liou JP); (Chen CP); 姚賢宗(Hsien-Tsung Yao); (Chiang YK); (Tan UK); (Chen CT); (Chu CY); (Wu SY); (Yeh TK); (Lin CY); (Hsieh HP)*
國家衛生研究院 2009-07-23 Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice Wu, CH;Hung, MS;Song, JS;Yeh, TK;Chou, MC;Chu, CM;Jan, JJ;Hsieh, MT;Tseng, SL;Chang, CP;Hsieh, WP;Lin, Y;Yeh, YN;Chung, WL;Kuo, CW;Lin, CY;Shy, HS;Chao, YS;Shia, KS
國家衛生研究院 2009-07-15 Biochemistry, pharmacokinetics, and toxicology of a potent and selective DPP8/9 inhibitor Wu, JJ;Tang, HK;Yeh, TK;Chen, CM;Shy, HS;Chu, YR;Chien, CH;Tsai, TY;Huang, YC;Huang, YL;Huang, CH;Tseng, HY;Jiaang, WT;Chao, YS;Chen, X
國家衛生研究院 2009-07 Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes Yao, HT;Lin, P;Chang, YW;Chen, CT;Chiang, MT;Chang, L;Kuo, YC;Tsai, HT;Yeh, TK
中國醫藥大學 2009-05 Effect of taurine supplementation on cytochrome P450 2E1 and oxidative stress in the liver and kidneys of rats with streptozotocin-induced diabetes 姚賢宗(Hsien-Tsung Yao); (Lin P); (Chang YW); (Chen CT); (Chiang MT); (Chang L); (KuoYC); (Tsai HT); (Yeh TK)
國家衛生研究院 2009-04-17 Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents Lai, MJ;Kuo, CC;Yeh, TK;Hsieh, HP;Chen, LT;Pan, WY;Hsu, KY;Chang, JY;Liou, JP
國家衛生研究院 2009-04-01 Rational design and synthesis of potent and long-lasting glutamic acid-based dipeptidyl peptidase IV inhibitors Tsai, TY;Hsu, T;Chen, CT;Cheng, JH;Chiou, MC;Huang, CH;Tseng, YJ;Yeh, TK;Huang, CY;Yeh, KC;Huang, YW;Wu, SH;Wang, MH;Chen, X;Chao, YS;Jiaang, WT
國家衛生研究院 2009-03-15 Novel trans-2-aryl-cyclopropylamine analogues as potent and selective dipeptidyl peptidase IV inhibitors Tsai, TY;Hsu, T;Chen, CT;Cheng, JH;Yeh, TK;Chen, X;Huang, CY;Chang, CN;Yeh, KC;Hsieh, SH;Chien, CH;Chang, YW;Huang, CH;Huang, YW;Huang, CL;Wu, SH;Wang, MH;Lu, CT;Chao, YS;Jiaang, WT
國家衛生研究院 2009-02 Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: An in vitro and in vivo study Wu, JP;Chang, LW;Yao, HT;Chang , H;Tsai, HT;Tsai , MH;Yeh, TK;Lin, P
國家衛生研究院 2008-07-09 Enhanced oral bioavailability of paclitaxel by D-alpha-tocopheryl polyethylene glycol 400 succinate in mice Ho, PY; Yeh, TK; Yao, HT; Lin, HL; Wu, HY; Lo, YK; Chang, YW; Chiang, TH; Wu, SHW; Chao, YS; Chen, CT
國家衛生研究院 2008-07 Computational and ultrastructural toxicology of a nanoparticle, Quantum Dot 705, in mice Lin, P;Chen, JW;Chang, LW;Wu, JP;Redding, L;Chang, H;Yeh, TK;Chung, SY;Tsai, MH;Wang, HJ;Kuo, YC;Yang, RSH
國家衛生研究院 2008-05 High-performance liquid chromatography-electrospray mass spectrometry for the simultaneous determination of multiple active components in Sheng-Mai San, a prescription of traditional Chinese medicine Chang, YW; Yao, HT; Chien, DS; Yeh, TK
國家衛生研究院 2008-02-28 Shengmai San reduces hepatic lipids and lipid peroxidation in rats fed on a high-cholesterol diet Yao, HT; Chang, YW; Chen, CT; Chiang, MT; Chang, L; Yeh, TK
國家衛生研究院 2008-02 The inhibitory effect of tannic acid on cytochrome P450 enzymes and NADPH-CYP reductase in rat and human liver microsomes Yao, HT; Chang, YW; Lan, SJ; Yeh, TK
國家衛生研究院 2007-10-01 Rapid and sensitive determination of fentanyl in dog plasma by on-line solid-phase extraction integrated with a hydrophilic column coupled to tandem mass spectrometry Chang, YW; Yao, HT; Chao, YS; Yeh, TK
國家衛生研究院 2007-10 Differential effects of arsenic on cyp1 enzymes in vitro and in vivo Wu, JP;Chang, LW;Lin, PP;Yao, HT;Chang, H;Wang, YJ;Yeh, TK;Tsai, MH;Tsai, HT
國家衛生研究院 2007-09-15 Quantitative determination of salidroside in rat plasma by on-line solid-phase extraction integrated with high-performance liquid chromatography/electrospray ionization tandem mass spectrometry Chang, YW; Yao, HT; Hsieh, SH; Lu, TJ; Yeh, TK
國家衛生研究院 2007-09 Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment Yang, RH; Chang, LW; Wu, JP; Tsai, MH; Wang, HJ; Kuo, YC; Yeh, TK; Yang, CS; Lin, P
國家衛生研究院 2007-07 Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes Yao, HT; Wu, YS; Chang, YW; Hsieh, HP; Chen, WC; Lan, SJ; Chen, CT; Chao, YS; Chang, L; Sun, HY; Yeh, TK
國家衛生研究院 2007-02-01 Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study Chang, YW; Chen, WC; Lin, KT; Chang, L; Yao, HT; Hsieh, HP; Lan, SJ; Chen, CT; Chao, YS; Yeh, TK
國家衛生研究院 2006-12 Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats Chang, YW; Yeh, TK; Lin, KT; Chen, WC; Yao, HT; Lan, SJ; Wu, YS; Hsieh, HP; Chen, CM; Chen, CT
國家衛生研究院 2006-11-25 The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes Yao, HT; Chang, YW; Lan, SJ; Chen, CT; Hsu, JTA; Yeh, TK
國家衛生研究院 2006-10 Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents Liou, JP;Mahindroo, N;Chang, CW;Guo, FM;Lee, SWH;Tan, UK;Yeh, TK;Kuo, CC;Chang, YW;Lu, PH;Tung, YS;Lin, KT;Chang, JY;Hsieh, HP
臺北醫學大學 2006 Structure-Activity Relationship Studies of 3-Aroylindoles as Potent Antimitotic Agents 劉景平; Liou JP; Mahindroo N; Chang CW; Guo FM; Lee SW; Yeh TK; Tan UK; Kuo CC; Chang YW; Lu PH; Tung YS;

Showing items 126-169 of 169  (4 Page(s) Totally)
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