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Showing items 76-125 of 169 (4 Page(s) Totally)
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Institution	Date	Title	Author
國家衛生研究院	2016-07	In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71	Ho, JY;Chern, JH;Hsieh, CF;Liu, ST;Liu, CJ;Wang, YS;Kuo, TW;Hsu, SJ;Yeh, TK;Shih, SR;Hsieh, PW;Chiu, CH;Horng, JT
國家衛生研究院	2016-05	N-Indolylglycosides bearing modifications at the glucose C6-Position as Sodium-Dependent Glucose Co-transporter 2 inhibitors	Chu, KF;Yao, CH;Song, JS;Chen, CT;Yeh, TK;Hsieh, TC;Huang, CY;Wang, MH;Wu, SH;Chang, WE;Chao, YS;Lee, JC
國家衛生研究院	2016-01	2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition	Nepali, K;Kumar, S;Huang, HL;Kuo, FC;Lee, CH;Kuo, CC;Yeh, TK;Li, YH;Chang, JY;Liou, JP;Lee, HY
國家衛生研究院	2016-01	Phenyl benzenesulfonylhydrazides exhibit selective Indoleamine 2,3-Dioxygenase inhibition with potent in vivo pharmacodynamic activity and antitumor efficacy	Lin, SY;Yeh, TK;Kuo, CC;Song, JS;Cheng, MF;Liao, FY;Chao, MW;Huang, HL;Chen, YL;Yang, CY;Wu, MH;Hsieh, CL;Hsiao, WC;Peng, YH;Wu, JS;Lin, LM;Sun, MW;Chao, YS;Shih, C;Wu, SY;Pan, SL;Hung, MS;Ueng, SH
國家衛生研究院	2015-10	Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening	Wu, JS;Lin, SY;Liao, FY;Hsiao, WC;Lee, LC;Peng, YH;Hsieh, CL;Wu, MH;Song, JS;Yueh, A;Chen, CH;Yeh, SH;Liu, CY;Lin, SY;Yeh, TK;Hsu, JT;Shih, C;Ueng, SH;Hung, MS;Wu, SY
國家衛生研究院	2015-08	Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway	Chen, HH;Wang, TC;Lee, YC;Shen, PT;Chang, JY;Yeh, TK;Huang, CH;Chang, HH;Cheng, SY;Lin, CY;Shih, C;Chen, CT;Liu, WM;Chen, CH;Kuo, CC
國家衛生研究院	2015-08	Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform	Tsou, LK;Liu, YW;Chen, YY;Lo, CF;Yeh, TK;Wu, CH;Shia, KS;Shih, JC;Gary, BD;Pek, KY;Chen, CT
國家衛生研究院	2015-08	Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia	Hsieh, HP;Hsu, YC;Ke, YY;Shiao, HY;Chang, CW;Lin, WH;Hsu, TA;Yeh, TK;Chen, CT
國家衛生研究院	2015-07	Identification of a potent 5-phenyl-thiazol-2-ylamine-based inhibitor of FLT3 with activity against drug resistance-conferring point mutations	Chen, CT;Hsu, JTA;Lin, WH;Lu, CT;Yen, SC;Hsu, T;Huang, YL;Song, JS;Chen, CH;Chou, LH;Yen, KJ;Chen, CP;Kuo, PC;Huang, CL;Eugene Liu, H;Chao, YS;Yeh, TK;Jiaang, WT
國家衛生研究院	2015-01	1-Arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells	Liu, YM;Lee, HY;Chen, CH;Lee, CH;Wang, LT;Pan, SL;Lai, MJ;Yeh, TK;Liou, JP
臺北醫學大學	2015	1-Arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells	Liu, YM;Lee, HY;Chen, CH;Lee, CH;Wang, LT;Pan, SL;Lai, MJ;Yeh, TK;Liou, JP.
國立交通大學	2014-12-08T15:42:50Z	Enhancing precision of global positioning system using short-range distance baseline field	Chen, CS; Yeh, TK
國家衛生研究院	2014-11-19	咪唑-4-酮及咪唑-4-硫酮化合物	Shia, KS;Wu, CH;Yeh, TK;Chao, YS
國家衛生研究院	2014-11	Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent	Hsieh, HP;Kuo, CC;Chiu, JJ;Hsu, TA;Yeh, TK;Chen, CT
國家衛生研究院	2014-10	Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma	Shiao, HY;Hsu, TA;Lin, WH;Yang, TT;Hsieh, HF;Chen, CT;Yeh, TK;Hsieh, HP
國家衛生研究院	2014-08-15	Anticancer oral formulation	Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院	2014-06-04	抗癌口服制剂	Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院	2014-05	Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells	Lee, HY;Tsai, AC;Chen, MC;Shen, PJ;Cheng, YC;Kuo, CC;Pan, SL;Liu, YM;Liu, JF;Yeh, TK;Wang, JC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院	2014-04-21	咪唑-4-酮及咪唑-4-硫酮化合物	Shia, KS;Wu, CH;Yeh, TK;Chao, YS
國家衛生研究院	2014-04	Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones	Chang, CY;Chuang, HY;Lee, HY;Yeh, TK;Kuo, CC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院	2014-03	DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study	Shiao, HY;Hsu, TAJ;Chen, CT;Yeh, TK;Hsieh, HP
國家衛生研究院	2014-01-08	Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer	Lin, WH;Yeh, TK;Jiaang, WT;Yen, KJ;Chen, CH;Huang, CT;Yen, SC;Hsieh, SY;Chou, LH;Chen, CP;Chiu, CH;Kao, LC;Chao, YS;Chen, CT;Hsu, JTA
臺北醫學大學	2014	Azaindolylsulfonamides, with a More Selective Inhibitory Effect on Histone Deacetylase 6 Activity, Exhibit Antitumor Activity in Colorectal Cancer HCT116 Cells	Lee, HY;Tsai, AC;Chen, MC;Shen, PJ;Cheng, YC;Kuo, CC;Pan, SL;Liu, YM;Liu, JF;Yeh, TK;Wang, JC;Chang, CY;Chang, JY;Liou, JP.
臺北醫學大學	2014	Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones	Chang, CY;Chuang, HY;Lee, HY;Yeh, TK;Kuo, CC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院	2013-11-13	Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice	Chang, CP;Wu, CH;Song, JS;Chou, MC;Wong, YC;Lin, Y;Yeh, TK;Sadani, AA;Ou, MH;Chen, KH;Chen, PH;Kuo, PC;Tseng, CT;Chang, KH;Tseng, SL;Chao, YS;Hung, MS;Shia, KS
國家衛生研究院	2013-11	BPR0C305, an orally active microtubule-disrupting anticancer agent	Li, WT;Yeh, TK;Song, JS;Yang, YN;Chen, TW;Lin, CH;Chen, CP;Shen, CC;Hsieh, CC;Lin, HL;Chao, YS;Chen, CT
國家衛生研究院	2013-11	A development drug candidate targeting EGFR kinase for lung cancer: DBPR112	Hsieh, HP;Shiao, HY;Chen, CT;Yeh, TK
國家衛生研究院	2013-07-08	1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors	Lee, HY;Yang, CR;Lai, MJ;Huang, HL;Hsieh, YL;Liu, YM;Yeh, TK;Li, YH;Mehndiratta, S;Teng, CM;Liou, JP
國家衛生研究院	2013-07-08	Inside Cover: 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors(ChemBioChem 10/2013)	Lee, HY;Yang, CR;Lai, MJ;Huang, HL;Hsieh, YL;Liu, YM;Yeh, TK;Li, YH;Mehndiratta, S;Teng, CM;Liou, JP
國家衛生研究院	2013-07	CYP1A2 genetic polymorphisms are associated with early antidepressant escitalopram metabolism and adverse reactions	Kuo, HW;Liu, SC;Tsou, HH;Liu, SW;Lin, KM;Lu, SC;Hsiao, MC;Hsiao, CF;Liu, CY;Chen, CH;Lu, ML;Shen, WW;Tang, HS;Liu, SI;Chang, LH;Wu, HY;Chang, YS;Yeh, TK;Chen, AC;Liu, YL
國家衛生研究院	2013-06-05	Anticancer oral formulation	Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院	2013-06	Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Lin, WH;Hsu, JTA;Hsieh, SY;Chen, CT;Song, JS;Yen, SC;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Yang, YN;Chiu, CH;Chen, CP;Tseng, YJ;Yen, KJ;Yeh, CF;Chao, YS;Yeh, TK;Jiaang, WT
國家衛生研究院	2013-04-13	Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents	Lee, YZ;Yang, CW;Hsu, HY;Qiu, YQ;Yeh, TK;Chao, YS;Lee, SJ
國家衛生研究院	2013-04-07	BPR000K, a novel Aurora kinase inhibitor	Chao, YS;Hsu, JTA;Chen, CT;Yeh, TK;Pan, SL;Hsieh, HP
國家衛生研究院	2013-04-07	3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor	Ke, YY;Shiao, HY;Hsu, YC;Chang-Chu, Y;Wang, WC;Lee, YC;Lin, WH;Hsu, JTA;Chang, CW;Lin, CW;Yeh, TK;Chao, YS;Coumar, MS;Hsieh, HP
國家衛生研究院	2013-04-07	Development drug candidate targeting EGFR kinase: DBPR112	Sun, HY;Hsu, JTA;Chen, CT;Yeh, TK;Pan, SL;Chao, YS;Hsieh, HP
國家衛生研究院	2013-02-11	抗癌口服藥學組成物	Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院	2013-02	Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems	Lin, HM;Wang, JC;Hu, HS;Wu, PS;Wang, WH;Wu, SY;Yang, CC;Yeh, TK;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yueh, A
國家衛生研究院	2013-01-15	Imidazol-4-one and imidazole-4-thione compounds	Shia, KS;Wu, CH;Yeh, TK;Chao, YS
國家衛生研究院	2013-01	3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor	Ke, YY;Shiao, HY;Hsu, YC;Chu, CY;Wang, WC;Lee, YC;Lin, WH;Chen, CH;Hsu, JTA;Chang, CW;Lin, CW;Yeh, TK;Chao, YS;Coumar, MS;Hsieh, HP
國家衛生研究院	2012-12-13	Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity	Lee, YZ;Yang, CW;Hsu, HY;Qiu, YQ;Yeh, TK;Chang, HY;Chao, YS;Lee, SJ
國家衛生研究院	2012-11	BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia	Chen, CT;Lin, WH;Chou, LH;Chen, CP;Yen, SC;Huang, YL;Yeh, TK;Hsu, JTA;Jiaang, WI;Chao, YS
國家衛生研究院	2012-09	Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors	Yao, CH;Song, JS;Chen, CT;Yeh, TK;Hsieh, TC;Wu, SH;Huang, CY;Huang, YL;Wang, MH;Liu, YW;Tsai, CH;Kumar, CR;Lee, JC
國家衛生研究院	2012-09	Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization	Yeh, JY;Coumar, MS;Shiao, HY;Lin, TJ;Lee, YC;Hung, HC;Ko, S;Kuo, FM;Fang, MY;Huang, YL;Hsu, JT;Yeh, TK;Shih, SR;Chao, YS;Horng, JT;Hsieh, HP
國家衛生研究院	2012-06-07	3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Hsu, JT;Yeh, TK;Yen, SC;Chen, CT;Hsieh, SY;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Chiu, CH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Lin, WH;Jiaang, WT
國家衛生研究院	2012-06	Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats	Yao, HT;Chang, YW;Uramaru, N;Watanabe, Y;Kitamura, S;Kuo, YH;Lii, CK;Yeh, TK
國家衛生研究院	2012-04	Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo	Lai, MJ;Huang, HL;Pan, SL;Liu, YM;Peng, CY;Lee, HY;Yeh, TK;Huang, PH;Teng, CM;Chen, CS;Chuang, HY;Liou, JP
中國醫藥大學	2012-03	Synthesis and Biological Evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as Potent Histone Deacetylase Inhibitors with Antitumor Activity in Vivo	(Lai MJ);(Huang HL); (Pan SL);(Liu YM);彭婕妤(Chieh-Yu Peng);(Lee HY);(Yeh TK);(Huang PH); (Teng CM);(Chen CS);(Chuang HY);(Liou JP)*
國家衛生研究院	2012-02-01	Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature	Yeh, TK;Chen, JK;Lin, CH;Yang, MH;Yang, CS;Chou, FI;Peir, JJ;Wang, MY;Chang, WH;Tsai, MH;Tsai, HT;Lin, P
國家衛生研究院	2012-01	Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor	Lin, HM;Wang, JC;Hu, HS;Wu, PS;Yang, CC;Wu, CP;Pu, SY;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yeh, TK;Yueh, A

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