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Showing items 91-140 of 169  (4 Page(s) Totally)
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Institution Date Title Author
國家衛生研究院 2014-08-15 Anticancer oral formulation Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院 2014-06-04 抗癌口服制剂 Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院 2014-05 Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells Lee, HY;Tsai, AC;Chen, MC;Shen, PJ;Cheng, YC;Kuo, CC;Pan, SL;Liu, YM;Liu, JF;Yeh, TK;Wang, JC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院 2014-04-21 咪唑-4-酮及咪唑-4-硫酮化合物 Shia, KS;Wu, CH;Yeh, TK;Chao, YS
國家衛生研究院 2014-04 Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones Chang, CY;Chuang, HY;Lee, HY;Yeh, TK;Kuo, CC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院 2014-03 DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study Shiao, HY;Hsu, TAJ;Chen, CT;Yeh, TK;Hsieh, HP
國家衛生研究院 2014-01-08 Evaluation of the antitumor effects of BPR1J-340, a potent and selective FLT3 inhibitor, alone or in combination with an HDAC inhibitor, vorinostat, in AML cancer Lin, WH;Yeh, TK;Jiaang, WT;Yen, KJ;Chen, CH;Huang, CT;Yen, SC;Hsieh, SY;Chou, LH;Chen, CP;Chiu, CH;Kao, LC;Chao, YS;Chen, CT;Hsu, JTA
臺北醫學大學 2014 Azaindolylsulfonamides, with a More Selective Inhibitory Effect on Histone Deacetylase 6 Activity, Exhibit Antitumor Activity in Colorectal Cancer HCT116 Cells Lee, HY;Tsai, AC;Chen, MC;Shen, PJ;Cheng, YC;Kuo, CC;Pan, SL;Liu, YM;Liu, JF;Yeh, TK;Wang, JC;Chang, CY;Chang, JY;Liou, JP.
臺北醫學大學 2014 Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones Chang, CY;Chuang, HY;Lee, HY;Yeh, TK;Kuo, CC;Chang, CY;Chang, JY;Liou, JP
國家衛生研究院 2013-11-13 Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice Chang, CP;Wu, CH;Song, JS;Chou, MC;Wong, YC;Lin, Y;Yeh, TK;Sadani, AA;Ou, MH;Chen, KH;Chen, PH;Kuo, PC;Tseng, CT;Chang, KH;Tseng, SL;Chao, YS;Hung, MS;Shia, KS
國家衛生研究院 2013-11 BPR0C305, an orally active microtubule-disrupting anticancer agent Li, WT;Yeh, TK;Song, JS;Yang, YN;Chen, TW;Lin, CH;Chen, CP;Shen, CC;Hsieh, CC;Lin, HL;Chao, YS;Chen, CT
國家衛生研究院 2013-11 A development drug candidate targeting EGFR kinase for lung cancer: DBPR112 Hsieh, HP;Shiao, HY;Chen, CT;Yeh, TK
國家衛生研究院 2013-07-08 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors Lee, HY;Yang, CR;Lai, MJ;Huang, HL;Hsieh, YL;Liu, YM;Yeh, TK;Li, YH;Mehndiratta, S;Teng, CM;Liou, JP
國家衛生研究院 2013-07-08 Inside Cover: 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines histone deacetylase inhibitors are potent cytokine release suppressors(ChemBioChem 10/2013) Lee, HY;Yang, CR;Lai, MJ;Huang, HL;Hsieh, YL;Liu, YM;Yeh, TK;Li, YH;Mehndiratta, S;Teng, CM;Liou, JP
國家衛生研究院 2013-07 CYP1A2 genetic polymorphisms are associated with early antidepressant escitalopram metabolism and adverse reactions Kuo, HW;Liu, SC;Tsou, HH;Liu, SW;Lin, KM;Lu, SC;Hsiao, MC;Hsiao, CF;Liu, CY;Chen, CH;Lu, ML;Shen, WW;Tang, HS;Liu, SI;Chang, LH;Wu, HY;Chang, YS;Yeh, TK;Chen, AC;Liu, YL
國家衛生研究院 2013-06-05 Anticancer oral formulation Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院 2013-06 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Lin, WH;Hsu, JTA;Hsieh, SY;Chen, CT;Song, JS;Yen, SC;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Yang, YN;Chiu, CH;Chen, CP;Tseng, YJ;Yen, KJ;Yeh, CF;Chao, YS;Yeh, TK;Jiaang, WT
國家衛生研究院 2013-04-13 Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents Lee, YZ;Yang, CW;Hsu, HY;Qiu, YQ;Yeh, TK;Chao, YS;Lee, SJ
國家衛生研究院 2013-04-07 BPR000K, a novel Aurora kinase inhibitor Chao, YS;Hsu, JTA;Chen, CT;Yeh, TK;Pan, SL;Hsieh, HP
國家衛生研究院 2013-04-07 3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor Ke, YY;Shiao, HY;Hsu, YC;Chang-Chu, Y;Wang, WC;Lee, YC;Lin, WH;Hsu, JTA;Chang, CW;Lin, CW;Yeh, TK;Chao, YS;Coumar, MS;Hsieh, HP
國家衛生研究院 2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 Sun, HY;Hsu, JTA;Chen, CT;Yeh, TK;Pan, SL;Chao, YS;Hsieh, HP
國家衛生研究院 2013-02-11 抗癌口服藥學組成物 Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院 2013-02 Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems Lin, HM;Wang, JC;Hu, HS;Wu, PS;Wang, WH;Wu, SY;Yang, CC;Yeh, TK;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yueh, A
國家衛生研究院 2013-01-15 Imidazol-4-one and imidazole-4-thione compounds Shia, KS;Wu, CH;Yeh, TK;Chao, YS
國家衛生研究院 2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor Ke, YY;Shiao, HY;Hsu, YC;Chu, CY;Wang, WC;Lee, YC;Lin, WH;Chen, CH;Hsu, JTA;Chang, CW;Lin, CW;Yeh, TK;Chao, YS;Coumar, MS;Hsieh, HP
國家衛生研究院 2012-12-13 Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity Lee, YZ;Yang, CW;Hsu, HY;Qiu, YQ;Yeh, TK;Chang, HY;Chao, YS;Lee, SJ
國家衛生研究院 2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia Chen, CT;Lin, WH;Chou, LH;Chen, CP;Yen, SC;Huang, YL;Yeh, TK;Hsu, JTA;Jiaang, WI;Chao, YS
國家衛生研究院 2012-09 Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors Yao, CH;Song, JS;Chen, CT;Yeh, TK;Hsieh, TC;Wu, SH;Huang, CY;Huang, YL;Wang, MH;Liu, YW;Tsai, CH;Kumar, CR;Lee, JC
國家衛生研究院 2012-09 Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization Yeh, JY;Coumar, MS;Shiao, HY;Lin, TJ;Lee, YC;Hung, HC;Ko, S;Kuo, FM;Fang, MY;Huang, YL;Hsu, JT;Yeh, TK;Shih, SR;Chao, YS;Horng, JT;Hsieh, HP
國家衛生研究院 2012-06-07 3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Hsu, JT;Yeh, TK;Yen, SC;Chen, CT;Hsieh, SY;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Chiu, CH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Lin, WH;Jiaang, WT
國家衛生研究院 2012-06 Effects of Bu-Zhong-Yi-Qi-Tang on hepatic drug-metabolizing enzymes and plasma tolbutamide concentration in rats Yao, HT;Chang, YW;Uramaru, N;Watanabe, Y;Kitamura, S;Kuo, YH;Lii, CK;Yeh, TK
國家衛生研究院 2012-04 Synthesis and biological evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo Lai, MJ;Huang, HL;Pan, SL;Liu, YM;Peng, CY;Lee, HY;Yeh, TK;Huang, PH;Teng, CM;Chen, CS;Chuang, HY;Liou, JP
中國醫藥大學 2012-03 Synthesis and Biological Evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as Potent Histone Deacetylase Inhibitors with Antitumor Activity in Vivo (Lai MJ);(Huang HL); (Pan SL);(Liu YM);彭婕妤(Chieh-Yu Peng);(Lee HY);(Yeh TK);(Huang PH); (Teng CM);(Chen CS);(Chuang HY);(Liou JP)*
國家衛生研究院 2012-02-01 Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: Effects of size and particulate nature Yeh, TK;Chen, JK;Lin, CH;Yang, MH;Yang, CS;Chou, FI;Peir, JJ;Wang, MY;Chang, WH;Tsai, MH;Tsai, HT;Lin, P
國家衛生研究院 2012-01 Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor Lin, HM;Wang, JC;Hu, HS;Wu, PS;Yang, CC;Wu, CP;Pu, SY;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yeh, TK;Yueh, A
國家衛生研究院 2012-01 BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML Lin, WH;Jiaang, WT;Chen, CW;Yen, KJ;Hsieh, SY;Yen, SC;Chen, CP;Chang, KY;Chang, CY;Chang, TY;Huang, YL;Yeh, TK;Chao, YS;Chen, CT;Hsu, JT
國家衛生研究院 2011-09-27 Formulations of indol-3-yl-2-oxoacetamide compounds Yeh, TK;Chen, CT;Chao, YS
國家衛生研究院 2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells Cheung, CH;Lin, WH;Hsu, TA;Hour, TC;Yeh, TK;Ko, S;Lien, TW;Coumar, MS;Liu, JF;Lai, WY;Shiao, HY;Lee, TR;Hsieh, HP;Chang, JY
國家衛生研究院 2011-07 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3) Lin, WH;Hsieh, SY;Yen, SC;Chen, CT;Yeh, TK;Hsu, T;Lu, CT;Chen, CP;Chen, CW;Chou, LH;Huang, YL;Cheng, AH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Hsu, JT;Jiaang, WT
國家衛生研究院 2011-04-28 Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents Tung, YS;Coumar, MS;Wu, YS;Shiao, HY;Chang, JY;Liou, JP;Shukla, P;Chang, CW;Chang, CY;Kuo, CC;Yeh, TK;Lin, CY;Wu, JS;Wu, SY;Liao, CC;Hsieh, HP
國家衛生研究院 2011-03-27 Design and synthesis of potent Aurora kinase inhibitors Chu, CY;Mohane, CS;Hsu, JTA;Yeh, TK;Chen, CT;Chao, YS;Hsieh, HP
國家衛生研究院 2011-03 Effect of shengmai san on insulin resistance, tumor necrosis factor-alpha and oxidative stress in rats fed on a high-fat diet Yao, HT;Chiang, MT;Lii, CK;Chang, YW;Hsieh, SH;Lin, JH;Chou, RH;Yeh, TK
國家衛生研究院 2011-03 Potent EGFR tyrosine kinase inhibitors as anticancer agents Shiao, HY;Chu, CY;Hsu, JTA;Yeh, TK;Hsieh, HP
國家衛生研究院 2011-01-13 Discovery of novel N -Beta- d -Xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes Yao, CH;Song, JS;Chen, CT;Yeh, TK;Hung, MS;Chang, CC;Liu, YW;Yuan, MC;Hsieh, CJ;Huang, CY;Wang, MH;Chiu, CH;Hsieh, TC;Wu, SH;Hsiao, WC;Chu, KF;Tsai, CH;Chao, YS;Lee, JC
國家衛生研究院 2011-01 BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities Hu, CB;Chen, CP;Yeh, TK;Song, JS;Chang, CY;Chuu, JJ;Tung, FF;Ho, PY;Chen, TW;Lin, CH;Wang, MH;Chang, KY;Huang, CL;Lin, HL;Li, WT;Hwang, DR;Chern, JH;Hwang, LL;Chang, JY;Chao, YS;Chen, CT
國家衛生研究院 2010-11 Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus Yang, CW;Lee, YZ;Kang, IJ;Barnard, DL;Jan, JT;Lin, D;Huang, CW;Yeh, TK;Chao, YS;Lee, SJ
國家衛生研究院 2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency Wu, CH;Coumar, MS;Chu, CY;Lin, WH;Chen, YR;Chen, CT;Shiao, HY;Rafi, S;Wang, SY;Hsu, H;Chen, CH;Chang, CY;Chang, TY;Lien, TW;Fang, MY;Yeh, KC;Chen, CP;Yeh, TK;Hsieh, SH;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院 2010-10 Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities Lin, Y;Shia, KS;Hsiao, WC;Hsieh, WP;Yeh, TK;Tseng, SL;Hsu, CY;Chao, YS;Hung, MS
國家衛生研究院 2010-09-01 Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors Kang, IJ;Wang, LW;Yeh, TK;Lee, CC;Lee, YC;Hsu, SJ;Wu, YS;Wang, JC;Chao, YS;Yueh, A;Chern, JH
國家衛生研究院 2010-09 Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist Hung, MS;Chang, CP;Li, TC;Yeh, TK;Song, JS;Lin, Y;Wu, CH;Kuo, PC;Amancha, PK;Wong, YC;Hsiao, WC;Chao, YS;Shia, KS

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