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Institution Date Title Author
國家衛生研究院 2017-06 Mutagenesis of dengue virus protein NS2A revealed a novel domain responsible for virus-induced cytopathic effect and interactions between NS2A and NS2B transmembrane segments Wu, RH;Tsai, MH;Tsai, KN;Tian, JN;Wu, JS;Wu, SY;Chern, JH;Chen, CH;Yueh, A
國家衛生研究院 2017-01 A potent, selective, and orally bioavailable HCV NS5A inhibitor for treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazo l-2-yl)pyrrolidine-2-carboxamide Kang, IJ;Hsu, SJ;Yang, HY;Yeh, TK;Lee, CC;Lee, YC;Tian, YW;Song, JS;Hsu, TA;Chao, YS;Yueh, A;Chern, JH
國家衛生研究院 2015-10 Identification of substituted naphthotriazolediones as novel tryptophan 2,3-dioxygenase (TDO) inhibitors through structure-based virtual screening Wu, JS;Lin, SY;Liao, FY;Hsiao, WC;Lee, LC;Peng, YH;Hsieh, CL;Wu, MH;Song, JS;Yueh, A;Chen, CH;Yeh, SH;Liu, CY;Lin, SY;Yeh, TK;Hsu, JT;Shih, C;Ueng, SH;Hung, MS;Wu, SY
國家衛生研究院 2015-06-01 治療C型肝炎病毒感染之醫藥組成物 Chao, YS;Yueh, A
國家衛生研究院 2015-04 Scanning mutagenesis studies reveal a potential intramolecular interaction within the C-Terminal half of Dengue Virus NS2A involved in viral RNA replication and virus assembly and secretion Wu, RH;Tsai, MH;Chao, DY;Yueh, A
國家衛生研究院 2014-07 A novel approach to propagate flavivirus infectious cDNA clones in bacteria by introducing tandem repeat sequences upstream of virus genome Pu, SY;Wu, RH;Tsai, MH;Yang, CC;Chang, CM;Yueh, A
國家衛生研究院 2014-06-26 Baicalin, a metabolite of baicalein with antiviral activity against dengue virus Moghaddam, E;Teoh, BT;Sam, SS;Lani, R;Hassandarvish, P;Chik, Z;Yueh, A;Abubakar, S;Zandi, K
國家衛生研究院 2014-01 A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease Yang, CC;Hu, HS;Wu, RH;Wu, SH;Lee, SJ;Jiaang, WT;Chern, JH;Huang, ZS;Wu, HN;Chang, CM;Yueh, A
國家衛生研究院 2013-05 Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus Yang, CC;Tsai, MH;Hu, HS;Pu, SY;Wu, RH;Wu, SH;Lin, HM;Song, JS;Chao, YS;Yueh, A
國家衛生研究院 2013-02 Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems Lin, HM;Wang, JC;Hu, HS;Wu, PS;Wang, WH;Wu, SY;Yang, CC;Yeh, TK;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yueh, A
國家衛生研究院 2012-01 Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor Lin, HM;Wang, JC;Hu, HS;Wu, PS;Yang, CC;Wu, CP;Pu, SY;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yeh, TK;Yueh, A
國家衛生研究院 2011-04 Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors Kang, IJ;Wang, LW;Hsu, TA;Yueh, A;Lee, CC;Lee, YC;Lee, CY;Chao, YS;Shih, SR;Chern, JH
國家衛生研究院 2011-03 Successful propagation of flavivirus infectious cDNAs by a novel method to reduce the cryptic bacterial promoter activity of virus genomes Pu, SY;Wu, RH;Yang, CC;Jao, TM;Tsai, MH;Wang, JC;Lin, HM;Chao, YS;Yueh, A
國家衛生研究院 2011-01 Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay Yang, CC;Hsieh, YC;Lee, SJ;Wu, SH;Liao, CL;Tsao, CH;Chao, YS;Chern, JH;Wu, CP;Yueh, A
國家衛生研究院 2010-09-01 Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors Kang, IJ;Wang, LW;Yeh, TK;Lee, CC;Lee, YC;Hsu, SJ;Wu, YS;Wang, JC;Chao, YS;Yueh, A;Chern, JH
國家衛生研究院 2009-11-01 Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors Kang, IJ;Wang, LW;Hsu, SJ;Lee, CC;Lee, YC;Wu, YS;Yueh, A;Wang, JC;Hsu, TA;Chao, YS;Chern, JH
國家衛生研究院 2009-08-01 Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors Kang, IJ;Wang, LW;Hsu, SJ;Lee, CC;Lee, YC;Wu, YS;Hsu, TA;Yueh, A;Chao, YS;Chern, JH
國家衛生研究院 2009-02 A novel dengue vaccine candidate that induces cross-neutralizing antibodies and memory immunity Leng, CH;Liu, SJ;Tsai, JP;Li, YS;Chen, MY;Liu, HH;Lien, SP;Yueh, A;Hsiao, KN;Lai, LW;Liu, FC;Chong, P;Chen, HW
國家衛生研究院 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities Lu, IL; Huang, CF; Peng, YH; Lin, YT; Hsieh, HP; Chen, CT; Lien, TW; Lee, HJ; Mahindroo, N; Prakash, E; Yueh, A; Chen, HY; Goparaju, CMV; Chen, X; Liao, CC; Chao, YS; Hsu, JTA; Wu, SY
國家衛生研究院 2006-01 Interaction of Moloney murine leukemia virus capsid with Ubc9 and PIASy mediates SUMO-1 addition required early in infection Yueh, A; Leung, J; Bhattacharyya, S; Perrone, LA; Pu, SY; Goff, SP

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