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Institution Date Title Author
國家衛生研究院 2024-07-17 Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia Huang, YH;Lin, SY;Ou, LC;Huang, WC;Chao, PK;Chang, YC;Chang, HF;Lee, PT;Yeh, TK;Kuo, YH;Tien, YW;Xi, JH;Tao, PL;Chen, PY;Chuang, JY;Shih, C;Chen, CT;Tung, CW;Loh, HH;Ueng, SH;Yeh, SH
國家衛生研究院 2024-06-19 CXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity Liu, CC;Yang, WB;Chien, CH;Wu, CL;Chuang, JY;Chen, PY;Chu, JM;Cheng, SM;Qiu, LY;Chang, YC;Hwang, DY;Huang, CY;Lee, JS;Chang, KY
國家衛生研究院 2023-11 Mitochondrial ATP biogenesis regulated by vdac1 in tmem119+tumor-associated microglia and macrophages mediates high-grade glioma growth Wu, CR;Chen, YY;Lin, YJ;Wei, KC;Chang, KY;Feng, LY;Wu, AC;Chen, KT;Ren, AL;Nitta, R;Wu, J;Pant, A;Cho, KB;Mackall, C;Chuang, JY;Huang, CY;Li, G;Jackson, C;Chen, PY;Lim, M
國家衛生研究院 2023-10-05 A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects Hsu, YT;Chen, SR;Chang, YC;Chang, HF;Yeh, TK;Chuang, JY;Loh, HH;Hsieh, HP;Ueng, SH;Yeh, SH
國家衛生研究院 2023-07-31 Role of SH3GLB1 in the regulation of CD133 expression in GBM cells Chien, CH;Lai, CC;Chuang, JY;Chu, JM;Liu, CC;Chang, KY
國家衛生研究院 2023-07-22 The complex role of eicosanoids in the brain: Implications for brain tumor development and therapeutic opportunities Chen, HC;Chang, WC;Chuang, JY;Chang, KY;Liou, JP;Hsu, TI
國家衛生研究院 2022-12-05 Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation Kuppusamy, R;Hsu, YT;Ke, YY;Chang, PW;Chang, YC;Chang, HF;Wang, PC;Lin, YH;Huang, YC;Yeh, TK;Chuang, JY;Loh, HH;Shih, C;Chen, CT;Yeh, SH;Ueng, SH
國家衛生研究院 2022-07-13 SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma Chien, CH;Yang, WB;Chuang, JY;Lee, JS;Liao, WA;Huang, CY;Chen, PY;Wu, AC;Yang, ST;Lai, CC;Chi, PI;Chu, JM;Cheng, SM;Liu, CC;Hwang, DY;Chen, SH;Chang, KY
國家衛生研究院 2022-03-25 Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation Tsai, YT;Lo, WL;Chen, PY;Ko, CY;Chuang, JY;Kao, TJ;Yang, WB;Chang, KY;Hung, CY;Kikkawa, U;Chang, WC;Hsu, TI
國家衛生研究院 2022-02-02 HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells Wu, AC;Yang, WB;Chang, KY;Lee, JS;Liou, JP;Su, RY;Cheng, SM;Hwang, DY;Kikkawa, U;Hsu, TI;Wang, CY;Chang, WC;Chen, PY;Chuang, JY
國家衛生研究院 2021-12-20 L-selectin activation regulates Rho GTPase activity via Ca(+2) influx in Sertoli cell line, ASC-17D cells[Erratum:Biochemical and Biophysical Research Communications. 2020 May;525(4):1011-1017.] Limanjaya, I;Hsu, TI;Chuang, JY;Kao, TJ
國家衛生研究院 2021-10-08 Develop and apply electrocardiography-based risk score to identify community-based elderly individuals at high-risk of mortality Lu, TP;Chattopadhyay, A;Lu, KC;Chuang, JY;Yeh, SS;Chang, IS;Chen, CJ;Wu, IC;Hsu, CC;Chen, TY;Tseng, WT;Hsiung, CA;Juang, JJ
國家衛生研究院 2021-09-28 Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells Yang, WB;Wu, AC;Hsu, TI;Liou, JP;Lo, WL;Chang, KY;Chen, PY;Kikkawa, U;Yang, ST;Kao, TJ;Chen, RM;Chang, WC;Ko, CY;Chuang, JY
國家衛生研究院 2021-08-10 Vav2 is required for Netrin-1 receptor-class-specific spinal motor axon guidance Tsou, YS;Wang, CY;Chang, MY;Hsu, TI;Wu, MT;Wu, YH;Tsai, WL;Chuang, JY;Kao, TJ
國家衛生研究院 2021-05-31 NBM-BMX, an HDAC8 inhibitor, overcomes temozolomide resistance in glioblastoma multiforme by downregulating the beta-Cateninic-Myc/SOX2 pathway and upregulating p53-mediated MGMT inhibition Tsai, CY;Ko, HJ;Chiou, SJ;Lai, YL;Hou, CC;Javaria, T;Huang, ZY;Cheng, TS;Hsu, TI;Chuang, JY;Kwan, AL;Chuang, TH;Huang, CYF;Loh, JK;Hong, YR
國家衛生研究院 2021-05-14 Transferrin modified gsh sensitive hyaluronic acid derivative micelle to deliver hsp90 inhibitors to enhance the therapeutic efficacy of brain cancers Debele, TA;Wu, PC;Wei, YF;Chuang, JY;Chang, KY;Tsai, JH;Su, WP
國家衛生研究院 2021-03-16 Paxillin is required for proper spinal motor axon growth into the limb Tsai, WL;Chang, CJ;Wang, CY;Hsu, TI;Chang, MY;Wu, YH;Chang, PS;Lin, KL;Chuang, JY;Kania, A;Kao, TJ
國家衛生研究院 2021-03-08 Dissecting the mechanism of temozolomide resistance and its association with the regulatory roles of intracellular reactive oxygen species in glioblastoma Chien, CH;Hsueh, WT;Chuang, JY;Chang, KY
國家衛生研究院 2020-04-24 Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma Yang, WB;Hsu, CC;Hsu, TI;Liou, JP;Chang, KY;Chen, PY;Liu, JJ;Yang, ST;Wang, JY;Yeh, SH;Chen, RM;Chang, WC;Chuang, JY
國家衛生研究院 2020-04-15 Betulinic acid-mediated tuning of PERK/CHOP signaling by Sp1 inhibition as a novel therapeutic strategy for glioblastoma Lo, WL;Hsu, TI;Yang, WB;Kao, TJ;Wu, MH;Huang, YN;Yeh, SH;Chuang, JY
國家衛生研究院 2020-04 Pharmacological studies of morphine in a novel humanized mu opioid receptor mouse model Huang, YH;Yeh, SH;Loh, HH;Chuang, JY
國家衛生研究院 2020-03-13 L-selectin activation regulates Rho GTPase activity via Ca(+2) influx in Sertoli cell line, ASC-17D cells Limanjaya, I;Hsu, TI;Chuang, JY;Kao, TJ
國家衛生研究院 2020-02-06 Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu opioid receptor splice variants Huang, YH;Wu, YW;Chuang, JY;Chang, YC;Chang, HF;Tao, PL;Loh, HH;Yeh, SH
國家衛生研究院 2019-12-26 AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis Chen, TC;Chuang, JY;Ko, CY;Kao, TJ;Yang, PY;Yu, CH;Liu, MS;Hu, SL;Tsai, YT;Chan, H;Chang, WC;Hsu, TI
國家衛生研究院 2019-11-11 ANGPTL4 induces TMZ resistance of glioblastoma by promoting cancer stemness enrichment via the EGFR/AKT/4E-BP1 cascade Tsai, YT;Wu, AC;Yang, WB;Kao, TJ;Chuang, JY;Chang, WC;Hsu, TI

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