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机构 日期 题名 作者
國家衛生研究院 2023-07-22 The complex role of eicosanoids in the brain: Implications for brain tumor development and therapeutic opportunities Chen, HC;Chang, WC;Chuang, JY;Chang, KY;Liou, JP;Hsu, TI
國家衛生研究院 2022-12-05 Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation Kuppusamy, R;Hsu, YT;Ke, YY;Chang, PW;Chang, YC;Chang, HF;Wang, PC;Lin, YH;Huang, YC;Yeh, TK;Chuang, JY;Loh, HH;Shih, C;Chen, CT;Yeh, SH;Ueng, SH
國家衛生研究院 2022-07-13 SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma Chien, CH;Yang, WB;Chuang, JY;Lee, JS;Liao, WA;Huang, CY;Chen, PY;Wu, AC;Yang, ST;Lai, CC;Chi, PI;Chu, JM;Cheng, SM;Liu, CC;Hwang, DY;Chen, SH;Chang, KY
國家衛生研究院 2022-03-25 Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation Tsai, YT;Lo, WL;Chen, PY;Ko, CY;Chuang, JY;Kao, TJ;Yang, WB;Chang, KY;Hung, CY;Kikkawa, U;Chang, WC;Hsu, TI
國家衛生研究院 2022-02-02 HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells Wu, AC;Yang, WB;Chang, KY;Lee, JS;Liou, JP;Su, RY;Cheng, SM;Hwang, DY;Kikkawa, U;Hsu, TI;Wang, CY;Chang, WC;Chen, PY;Chuang, JY
國家衛生研究院 2021-12-20 L-selectin activation regulates Rho GTPase activity via Ca(+2) influx in Sertoli cell line, ASC-17D cells[Erratum:Biochemical and Biophysical Research Communications. 2020 May;525(4):1011-1017.] Limanjaya, I;Hsu, TI;Chuang, JY;Kao, TJ
國家衛生研究院 2021-10-08 Develop and apply electrocardiography-based risk score to identify community-based elderly individuals at high-risk of mortality Lu, TP;Chattopadhyay, A;Lu, KC;Chuang, JY;Yeh, SS;Chang, IS;Chen, CJ;Wu, IC;Hsu, CC;Chen, TY;Tseng, WT;Hsiung, CA;Juang, JJ
國家衛生研究院 2021-09-28 Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells Yang, WB;Wu, AC;Hsu, TI;Liou, JP;Lo, WL;Chang, KY;Chen, PY;Kikkawa, U;Yang, ST;Kao, TJ;Chen, RM;Chang, WC;Ko, CY;Chuang, JY
國家衛生研究院 2021-08-10 Vav2 is required for Netrin-1 receptor-class-specific spinal motor axon guidance Tsou, YS;Wang, CY;Chang, MY;Hsu, TI;Wu, MT;Wu, YH;Tsai, WL;Chuang, JY;Kao, TJ
國家衛生研究院 2021-05-31 NBM-BMX, an HDAC8 inhibitor, overcomes temozolomide resistance in glioblastoma multiforme by downregulating the beta-Cateninic-Myc/SOX2 pathway and upregulating p53-mediated MGMT inhibition Tsai, CY;Ko, HJ;Chiou, SJ;Lai, YL;Hou, CC;Javaria, T;Huang, ZY;Cheng, TS;Hsu, TI;Chuang, JY;Kwan, AL;Chuang, TH;Huang, CYF;Loh, JK;Hong, YR
國家衛生研究院 2021-05-14 Transferrin modified gsh sensitive hyaluronic acid derivative micelle to deliver hsp90 inhibitors to enhance the therapeutic efficacy of brain cancers Debele, TA;Wu, PC;Wei, YF;Chuang, JY;Chang, KY;Tsai, JH;Su, WP
國家衛生研究院 2021-03-16 Paxillin is required for proper spinal motor axon growth into the limb Tsai, WL;Chang, CJ;Wang, CY;Hsu, TI;Chang, MY;Wu, YH;Chang, PS;Lin, KL;Chuang, JY;Kania, A;Kao, TJ
國家衛生研究院 2021-03-08 Dissecting the mechanism of temozolomide resistance and its association with the regulatory roles of intracellular reactive oxygen species in glioblastoma Chien, CH;Hsueh, WT;Chuang, JY;Chang, KY
國家衛生研究院 2020-04-24 Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma Yang, WB;Hsu, CC;Hsu, TI;Liou, JP;Chang, KY;Chen, PY;Liu, JJ;Yang, ST;Wang, JY;Yeh, SH;Chen, RM;Chang, WC;Chuang, JY
國家衛生研究院 2020-04-15 Betulinic acid-mediated tuning of PERK/CHOP signaling by Sp1 inhibition as a novel therapeutic strategy for glioblastoma Lo, WL;Hsu, TI;Yang, WB;Kao, TJ;Wu, MH;Huang, YN;Yeh, SH;Chuang, JY
國家衛生研究院 2020-04 Pharmacological studies of morphine in a novel humanized mu opioid receptor mouse model Huang, YH;Yeh, SH;Loh, HH;Chuang, JY
國家衛生研究院 2020-03-13 L-selectin activation regulates Rho GTPase activity via Ca(+2) influx in Sertoli cell line, ASC-17D cells Limanjaya, I;Hsu, TI;Chuang, JY;Kao, TJ
國家衛生研究院 2020-02-06 Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu opioid receptor splice variants Huang, YH;Wu, YW;Chuang, JY;Chang, YC;Chang, HF;Tao, PL;Loh, HH;Yeh, SH
國家衛生研究院 2019-12-26 AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis Chen, TC;Chuang, JY;Ko, CY;Kao, TJ;Yang, PY;Yu, CH;Liu, MS;Hu, SL;Tsai, YT;Chan, H;Chang, WC;Hsu, TI
國家衛生研究院 2019-11-11 ANGPTL4 induces TMZ resistance of glioblastoma by promoting cancer stemness enrichment via the EGFR/AKT/4E-BP1 cascade Tsai, YT;Wu, AC;Yang, WB;Kao, TJ;Chuang, JY;Chang, WC;Hsu, TI
國家衛生研究院 2019-10-19 Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets Chien, CH;Chuang, JY;Yang, ST;Yang, WB;Chen, PY;Hsu, TI;Huang, CY;Lo, WL;Yang, KY;Liu, MS;Chu, JM;Chung, PH;Liu, JJ;Chou, SW;Chen, SH;Chang, KY
國家衛生研究院 2019-09-16 CYP17A1 maintains the survival of glioblastomas by regulating SAR1-Mediated endoplasmic reticulum health and redox homeostasis Lin, HY;Ko, CY;Kao, TJ;Yang, WB;Tsai, YT;Chuang, JY;Hu, SL;Yang, PY;Lo, WL;Hsu, TI
國家衛生研究院 2019-09-03 Role of autophagy in therapeutic resistance of glioblastoma Chien, CH;Hsueh, WT;Chuang, JY;Chang, KY
國家衛生研究院 2019-07-03 BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine Chao, PK;Chang, HF;Chang, WT;Yeh, TK;Ou, LC;Chuang, JY;Tsu-An Hsu, J;Tao, PL;Loh, HH;Shih, C;Ueng, SH;Yeh, SH
國家衛生研究院 2019-07 CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation Wang, SM;Lin, HY;Chen, YL;Hsu, TI;Chuang, JY;Kao, TJ;Ko, CY
國家衛生研究院 2019-02-20 Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice Chao, PK;Chang, HF;Ou, LC;Chuang, JY;Lee, PT;Chang, WT;Chen, SC;Ueng, SH;Hsu, JT;Tao, PL;Law, PY;Loh, HH;Yeh, SH
國家衛生研究院 2018-08-04 Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress Wu, CC;Lee, PT;Kao, TJ;Chou, SY;Su, RY;Lee, YC;Yeh, SH;Liou, JP;Hsu, TI;Su, TP;Chuang, CK;Chang, WC;Chuang, JY
國家衛生研究院 2018-07-18 Dehydroepiandrosterone induces temozolomide resistance through modulating phosphorylation and acetylation of Sp1 in glioblastoma Yang, WB;Chuang, JY;Ko, CY;Chang, WC;Hsu, TI
國家衛生研究院 2018-07 Mitochondrial SOD2 is the mainstay to protect the stemness-featured glioblastoma cells against drug-induced reactive oxygen stress Chang, KY;Chien, CH;Chu, JM;Chung, PH;Liu, MS;Chuang, JY
國家衛生研究院 2018-07 Sp1 acetylation associates with stemness characteristics in temozolomide-resistant glioblastoma Chuang, JY;Hsu, CC;Chang, KY;Chang, WC
國家衛生研究院 2017-11 Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma Chang, KY;Huang, CT;Hsu, TI;Hsu, CC;Liu, JJ;Chuang, CK;Hung, JJ;Chang, WC;Tsai, KK;Chuang, JY
國家衛生研究院 2017-08-12 Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase Chang, KY;Hsu, TI;Hsu, CC;Tsai, SY;Liu, JJ;Chou, SW;Liu, MS;Liou, JP;Ko, CY;Chen, KY;Hung, JJ;Chang, WC;Chuang, CK;Kao, TJ;Chuang, JY
國家衛生研究院 2017-05-22 Upregulation of CYP17A1 by Sp1-mediated DNA demethylation confers temozolomide resistance through DHEA-mediated protection in glioma Chuang, JY;Lo, WL;Ko, CY;Chou, SY;Chen, RM;Chang, KY;Hung, JJ;Su, WC;Chang, WC;Hsu, TI
國家衛生研究院 2017-05-06 MDM2 degrades deacetylated nucleolin through ubiquitination to promote glioma stem-like cell enrichment for chemotherapeutic resistance Ko, CY;Lin, CH;Chuang, JY;Chang, WC;Hsu, TI
國家衛生研究院 2017-05 1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine Chao, PK;Ueng, SH;Ou, LC;Yeh, TK;Chang, WT;Chang, HF;Chen, SC;Tao, PL;Law, PY;Loh, HH;Cheng, MF;Chuang, JY;Chen, CT;Shih, C;Yeh, SH
國家衛生研究院 2017-04 Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury Chuang, JY;Kao, TJ;Lin, SH;Wu, AC;Lee, PT;Su, TP;Yeh, SH;Lee, YC;Wu, CC;Chang, WC
國家衛生研究院 2017-03 Mapping the naloxone binding sites on the mu-opioid receptor using cell-based photocrosslinkers Ke, YY;Huang, YH;Chien, WC;Loh, HH;Chuang, JY;Yeh, SH
國家衛生研究院 2016-11-18 Suberoylanilide hydroxamic acid represses glioma stem-like cells Hsu, CC;Chang, WC;Hsu, TI;Liu, JJ;Yeh, SH;Wang, JY;Liou, JP;Ko, CY;Chang, KY;Chuang, JY
國家衛生研究院 2016-06 The sigma-1 receptor-zinc finger protein 179 pathway protects against hydrogen peroxide-induced cell injury Su, TC;Lin, SH;Lee, PT;Yeh, SH;Hsieh, TH;Chou, SY;Su, TP;Hung, JJ;Chang, WC;Lee, YC;Chuang, JY
國家衛生研究院 2014-12-01 Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling Lee, PT;Chao, PK;Ou, LC;Chuang, JY;Lin, YC;Chen, SC;Chang, HF;Law, PY;Loh, HH;Chao, YS;Su, TP;Yeh, SH
亞洲大學 2014-05 Syk/JNK/AP-1 Signaling Pathway Mediates Interleukin-6-Promoted Cell Migration in Oral Squamous Cell Carcinoma Chuang, JY;Chuang, JY;黃元勵;HUANG, YUAN-LI;Yen, WL;Yen, WL;Chiang, IP;Chiang, IP;Tsai, MH;Tsai, MH;Tan, CH;Tan, CH
亞洲大學 2014-03 Syk/JNK/AP-1 Signaling Pathway Mediates Interleukin-6-Promoted Cell Migration in Oral Squamous Cell Carcinoma Chuang, JY;Chuang, JY;黃元勵;HUANG, YUAN-LI;Yen, WL;Yen, WL;Chiang, IP;Chiang, IP;Tsai, MH;Tsai, MH;Tan, CH;Tan, CH
臺北醫學大學 2014 Phosphorylation of p300 increases its protein degradation to enhance the lung cancer progression Wang, SA;Hung, CY;Chuang, JY;Chang, WC;Hsu, TI;Hung, JJ
臺北醫學大學 2014 Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis Yang, HC;Chuang, JY;Jeng, WY;Liu, CI;Wang, AH;Lu, PJ;
臺北醫學大學 2014 Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis Yang, HC;Chuang, JY;Jeng, WY;Liu, CI;Wang, AH;Lu, PJ;
國立臺灣大學 2008 Involvement of MCAF1 in the synergistically activation of the Epstein-Barr virus promoters by Rta and Zta Chang LK; Chuang JY; Chang CW; Ichimura T; Nakao M; Liu ST
國立臺灣大學 2006-01 Sumoylation of Rta of Epstein-Barr virus is preferentially enhanced by PIASxb. Liu, ST; Wang, WH; Hong, YR; Chuang, JY; Lu, PJ; Chang, LK
高雄醫學大學 2006 PIASxbeta優先加強Epstein-Barr virus中 Rta 蛋白之Sumoylation  劉世東;王文宏;洪義人;莊健盈;呂佩融;張麗冠  ; Liu ST;Wang WH;Hong YR;Chuang JY;Lu PJ;Chang LK  
國立臺灣大學 2005-01 Activation of Sp1-mediated transcription by Rta of Epstein-Barr Virus via an interaction with MCAF1. Chang, LK; Chuang, JY; Hong, YR; Ichimura, T; Nakao, M; Liu, ST
慈濟大學 2005 Berberine inhibits arylamine N-acetyltransferase activity and gene expression in mouse leukemia L 1210 cells Lin, SS;Chung, JG;Lin, JP;Chuang, JY;Chang, WC;Wu, JY;Tyan, YS

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