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"coumar ms"

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Institution	Date	Title	Author
國家衛生研究院	2012-05-11	作為極光激酶抑制劑之稠合雙環嘧啶化合物	Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2012-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2011-09-23	BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo	Hsieh, HP;Cheung, CHA;Lin, WH;Hsu, TA;Coumar, MS;Chao, YS;Chang, JY
國家衛生研究院	2011-08	BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells	Cheung, CH;Lin, WH;Hsu, TA;Hour, TC;Yeh, TK;Ko, S;Lien, TW;Coumar, MS;Liu, JF;Lai, WY;Shiao, HY;Lee, TR;Hsieh, HP;Chang, JY
國家衛生研究院	2011-06	Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10)	Cheung, CHA;Coumar, MS;Chang, JY;Hsieh, HP
國家衛生研究院	2011-04-28	Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents	Tung, YS;Coumar, MS;Wu, YS;Shiao, HY;Chang, JY;Liou, JP;Shukla, P;Chang, CW;Chang, CY;Kuo, CC;Yeh, TK;Lin, CY;Wu, JS;Wu, SY;Liao, CC;Hsieh, HP
國家衛生研究院	2010-12	Discovery of non-glycoside sodium-dependent glucose Co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening	Wu, JS;Peng, YH;Wu, JM;Hsieh, CJ;Wu, SH;Coumar, MS;Song, JS;Lee, JC;Tsai, CH;Chen, CT;Liu, YW;Chao, YS;Wu, SY
國家衛生研究院	2010-10-28	Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency	Wu, CH;Coumar, MS;Chu, CY;Lin, WH;Chen, YR;Chen, CT;Shiao, HY;Rafi, S;Wang, SY;Hsu, H;Chen, CH;Chang, CY;Chang, TY;Lien, TW;Fang, MY;Yeh, KC;Chen, CP;Yeh, TK;Hsieh, SH;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院	2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院	2010-08	Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models	Hsieh, HP;Chu, CY;Coumar, MS;Lin, WH;Chen, CT;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院	2010-02-25	Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives	Yeh, JY;Coumar, MS;Horng, JT;Shiao, HY;Kuo, FM;Lee, HL;Chen, IC;Chang, CW;Tang, WF;Tseng, SN;Chen, CJ;Shih, SR;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院	2010-02-01	Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor	Coumar, MS;Tsai, MT;Chu, CY;Uang, BJ;Lin, WH;Chang, CY;Chang, TY;Leou, JS;Teng, CH;Wu, JS;Fang, MY;Chen, CH;Hsu, JTA;Wu, SY;Chao, YS;Hsieh, HP
國家衛生研究院	2009-08-13	Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach	Wu, YS;Coumar, MS;Chang, JY;Sun, HY;Kuo, FM;Kuo, CC;Chen, YJ;Chang, CY;Hsiao, CL;Liou, JP;Chen, CP;Yao, HT;Chiang, YK;Tan, UK;Chen, CT;Chu, CY;Wu, SY;Yeh, TK;Lin, CY;Hsieh, HP
中國醫藥大學	2009-08	Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach.	(Wu YS); (Coumar MS); (Chang JY); (Sun HY); (Kuo FM); (Kuo CC); (Chen YJ); (Chang CY); (Hsiao CL); (Liou JP); (Chen CP); 姚賢宗(Hsien-Tsung Yao); (Chiang YK); (Tan UK); (Chen CT); (Chu CY); (Wu SY); (Yeh TK); (Lin CY); (Hsieh HP)*
國家衛生研究院	2009-07-23	Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity	Chiang, YK;Kuo, CC;Wu, YS;Chen, CT;Coumar, MS;Wu, JS;Hsieh, HP;Chang, CY;Jseng, HY;Wu, MH;Leou, JS;Song, JS;Chang, JY;Lyu, PC;Chao, YS;Wu, SY
國家衛生研究院	2009-07-03	Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers	Cheung, CH;Chen, HH;Kuo, CC;Chang, CY;Coumar, MS;Hsieh, HP;Chang, JY
國家衛生研究院	2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	Lin, CH;Peng, YH;Coumar, MS;Chittimalla, SK;Liao, CC;Lyn, PC;Huang, CC;Lien, TW;Lin, WH;Hsu, JT;Cheng, JH;Chen, X;Wu, JS;Chao, YS;Lee, HJ;Juo, CG;Wu, SY;Hsieh, HP
國家衛生研究院	2009-04	Aurora kinase inhibitors in preclinical and clinical testing	Cheung, CH;Coumar, MS;Hsieh, HP;Chang, JY
國家衛生研究院	2009-03	Advances in Aurora kinase inhibitor patents	Coumar, MS;Cheung, CHA;Chang, JY;Hsieh, HP
國家衛生研究院	2009-03	Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors	Hsieh, HP;Coumar, MS;Lin, CW;Reddy, GR;Tsai, MT;Lin, WH;Hsu, TA;Wu, SY
國家衛生研究院	2009-02-26	Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity	Coumar, MS;Leou, JS;Shukla, P;Wu, JS;Dixit, AK;Lin, WH;Chang, CY;Lien, TW;Tan, UK;Chen, CH;Hsu, JTA;Chao, YS;Wu, SY;Hsieh, HP
國家衛生研究院	2008-12-25	Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents	Reddy, GR;Kuo, CC;Tan, UK;Coumar, MS;Chang, CY;Chiang, YK;Lai, MJ;Yeh, JY;Wu, SY;Chang, JY;Liou, JP;Hsieh, HP
國家衛生研究院	2008-06	Synthesis, beta-adrenergic receptor binding and antihypertensive potential of vanillin-derived phenoxypropanolamines	Coumar, MS; Jindal, DP; Bruni, G; Massarelli, P; Singh, R; Sharma, AK; Nandakumar, K; Bodhankar, SL
國家衛生研究院	2008-03-01	Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold	Coumar, MS; Wu, JS; Leou, JS; Tan, UK; Chang, CY; Chang, TY; Lin, WH; Hsu, JTA; Chao, YS; Wu, SY; Hsieh, HP

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