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教育部委託研究計畫      計畫執行:國立臺灣大學圖書館
 
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機構 日期 題名 作者
國家衛生研究院 2025-01 Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design Tahiliani, H;Dhayalan, A;Li, MC;Hsieh, HP;Coumar, MS
國家衛生研究院 2023-02-07 Development of furanopyrimidine-based orally active third- generation EGFR inhibitors for the treatment of non-small cell lung cancer Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2022-02-07 Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2022-02 What can the anti-apoptotic molecule, BIRC5/Survivin, do in the autophagic world? Cheung, CH;Lin, TY;Sarvagalla, S;Coumar, MS;Cheng, SM;Leung, E
國家衛生研究院 2021-04-16 Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors Reddy, JS;Chen, CM;Coumar, MS;Sun, HY;Sun, N;Hsieh, HP
國家衛生研究院 2021-02-22 Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design Chandar Charles, MR;Li, MC;Hsieh, HP;Coumar, MS
國家衛生研究院 2020-08 The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells Chang, YC;Kondapuram, SK;Yang, TH;Syed, SB;Cheng, SM;Lin, TY;Lin, YC;Coumar, MS;Chang, JY;Leung, E;Cheung, CHA
國家衛生研究院 2020-07-07 Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors Syed, SB;Lin, SY;Arya, H;Fu, IH;Yeh, TK;Charles, MRC;Periyasamy, L;Hsieh, HP;Coumar, MS
國家衛生研究院 2020-05 Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors Lin, SY;Chang, CF;Coumar, MS;Chen, PY;Kuo, FM;Chen, CH;Li, MC;Lin, WH;Kuo, PC;Wang, SY;Li, AS;Lin, CY;Yang, CM;Yeh, TK;Song, JS;Hsu, JTA;Hsieh, HP
國家衛生研究院 2020-01 Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening Chandar Charles, MR;Mahesh, A;Lin, SY;Hsieh, HP;Dhayalan, A;Coumar, MS
國家衛生研究院 2019-10-15 BIRC5/Survivin is a novel ATG12?ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells Lin, TY;Chan, HH;Chen, SH;Sarvagalla, S;Chen, PS;Coumar, MS;Cheng, SM;Chang, YC;Lin, CH;Leung, E;Cheung, CHA
國家衛生研究院 2019-10-15 BIRC5/Survivin is a novel ATG12-ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells Lin, TY;Chan, HH;Chen, SH;Sarvagalla, S;Chen, PS;Coumar, MS;Cheng, SM;Chang, YC;Lin, CH;Leung, E;Cheung, CHA
國家衛生研究院 2019-09 Design of a potent anticancer lead inspired by natural products from traditional Indian medicine Arya, H;Yadav, CS;Lin, SY;Syed, SB;Charles, MRC;Kannadasan, S;Hsieh, HP;Singh, SS;Gajurel, PR;Coumar, MS
國家衛生研究院 2019-05-29 Insights for the design of protein lysine methyltransferase G9a inhibitors Charles, MRC;Dhayalan, A;Hsieh, HP;Coumar, MS
國家衛生研究院 2018-07-26 Delineating the active site architecture of G9a lysine methyltransferase through substrate and inhibitor binding mode analysis: A molecular dynamics study M, RCC;Hsieh, HP;Coumar, MS
國家衛生研究院 2017-08-11 Targeting P-glycoprotein: Investigation of piperine analogs for overcoming drug resistance in cancer Syed, SB;Arya, H;Fu, IH;Yeh, TK;Periyasamy, L;Hsieh, HP;Coumar, MS
國家衛生研究院 2017-07 Drug repurposing for chronic myeloid leukemia: In silico and in vitro investigation of DrugBank database for allosteric Bcr-Abl inhibitors Singh, VK;Chang, HH;Kuo, CC;Shiao, HY;Hsieh, HP;Coumar, MS
國家衛生研究院 2017-01-13 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院 2016-11-23 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院 2016-07 Therapeutic polymeric nanoparticles and the methods of making and using thereof: A patent evaluation of WO2015036792 Sarvagalla, S;Hsieh, HP;Coumar, MS
國家衛生研究院 2016-06-07 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院 2016-03 Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and in vitro testing for the anti-cancer drug target survivin Sarvagalla, S;Cheung, CHA;Tsai, JY;Hsieh, HP;Coumar, MS
國家衛生研究院 2015-08-20 Fused bicyclic pyrimidine compounds as Aurora kinase inhibitors Coumar, MS;Chao, YS;Hsu, TA;Wu, SY;Hsieh, HP
國家衛生研究院 2015-07-31 作為極光激酶抑制劑的稠合雙環嘧啶化合物 Hsieh, HP;Coumar, MS;Wu, SY;Hsu, TA;Chao, YS
國家衛生研究院 2015-07-22 作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物 Hsieh, HP;Coumar, MS;Hsu, TA;Lin, WH;Chen, YR;Chao, YS

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