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"hsieh hp"
顯示項目 1-50 / 265 (共6頁)
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| 國家衛生研究院 |
2025-07-25 |
Noncovalent interaction effects on the acyl radical reaction of bicyclo 2.2.2 octanone: Selective formation of rearrangement and cyclization products
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Chen, CM;Kuo, TC;Reddy, JS;Teoh, YN;Huang, JS;Lin, SK;Cheng, MJ;Hsieh, HP |
| 國家衛生研究院 |
2025-07-24 |
Unraveling Cathepsin S regulation in interleukin-7-mediated anti-tumor immunity reveals its targeting potential against oral cancer
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Chang, YC;Chen, SJ;Chen, SH;Hsiao, SY;Chen, LH;Chen, CH;Liu, CC;Chen, YW;Liu, KJ;Wu, SY;Chu, JM;Qiu, LY;Chiang, WF;Hsieh, HP;Hsueh, WY;Hsiao, JR;Shen, MR;Chang, JY;Chang, KY |
| 國家衛生研究院 |
2025-05-20 |
Structure-based design of potent and selective merTK inhibitors by modulating the conformation of alphaC helix
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Peng, YH;Li, MC;Yen, WC;Yeh, TK;Hsueh, CC;Kuo, FM;Lai, YL;Chang, L;Lee, LC;Chen, PY;Yen, KJ;Chang, TY;Sun, HY;Chang, CY;Hsieh, SH;Yang, CM;Hsieh, HP;Wu, SY |
| 國家衛生研究院 |
2025-03-25 |
KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules
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Pao, YS;Liao, KJ;Shiau, YC;Chao, MH;Li, MC;Lin, LM;Chang, HH;Yeh, HW;Chen, YJ;Chiu, YT;Pan, MY;Chang, YH;Shen, SY;Lin, SY;Cheng, HC;Lin, YC;Sun, YJ;Kuo, CC;Hsieh, HP;Wang, LH |
| 國家衛生研究院 |
2025-03-24 |
Identification and biological evaluation of a novel CLK4 inhibitor targeting alternative splicing in pancreatic cancer using structure-based virtual screening
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Yang, CL;Wu, YW;Tu, HJ;Yeh, YH;Lin, TE;Sung, TY;Li, MC;Yen, SC;Hsieh, JH;Yu, MC;Hsieh, SY;Hsieh, HP;Pan, SL;Hsu, KC |
| 國家衛生研究院 |
2025-01 |
Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models
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Tang, YC;Ou, JJ;Hsu, SC;Huang, CH;Lin, LM;Chang, HH;Wang, YH;Huang, ZT;Sun, M;Liu, KJ;Hung, YM;Lai, CY;Shih, C;Chen, CT;Chang, JY;Hsieh, HP;Jiaang, WT;Kuo, CC |
| 國家衛生研究院 |
2025-01 |
Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design
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Tahiliani, H;Dhayalan, A;Li, MC;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2024-12-30 |
Novel naphthyridones targeting pannexin 1 for colitis management
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Hsueh, WY;Wu, YL;Weng, MT;Liu, SY;Santavanond, JP;Liu, YC;Lin, C;Lai, CN;Lu, YR;Hsu, JY;Gao, HY;Lee, JC;Wei, SC;Lyu, PC;Poon, IKH;Hsieh, HP;Chiu, YH |
| 國家衛生研究院 |
2024-12 |
Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma
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Shih, WH;Huang, HL;HuangFu, WC;Lin, TE;Sung, TY;Li, MC;Huang, GL;Chang, YW;Yen, SC;Hsieh, HP;Hsu, KC;Pan, SL |
| 國家衛生研究院 |
2024-11-07 |
Novel approach to anti-tumour and anti-SARS-COV-2 drugs by modulating sialylation of N-glycans
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Li, WS;Perez, SJL;Chang, TT;Chen, CL;Wang, SH;Li, CW;Hsieh, HP;Wu, HC |
| 國家衛生研究院 |
2024-11-07 |
Discovery of DYRK1A inhibitors as potential treatment of pancreatic ductal adenocarcinoma (PDAC)
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Hsieh, HP;Zhang-Jian, YX;Hsu, KC;Pan, SL;Li, WS;Wu, HC |
| 國家衛生研究院 |
2024-11 |
DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration
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Lin, SY;Chang, YC;Tien, YW;Kuo, YH;Chang, HF;Ou, LC;Chen, YP;Chang, KH;Hsu, YT;Huang, YC;Yang, CM;Law, PY;Xi, JH;Tao, PL;Loh, HH;Yeh, TK;Zhuang, H;Hsieh, HP;Shih, C;Chen, CT;Yeh, SH;Ueng, SH |
| 國家衛生研究院 |
2024-11 |
Epithelial cell adhesion molecule induces induces Wnt receptor transcription to promote colorectal cancer progression
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Wu, HC;Panda, SS;Lee, CC;Shen, CN;Li, WS;Hsieh, HP |
| 國家衛生研究院 |
2024-06-24 |
Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease
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Yang, IH;Kuan, CY;Zhang, SL;Chen, ZY;Li, CH;Liang, YJ;Kuo, WT;Chang, CT;Lin, J;Hsieh, HP;Chang, JY;Lin, FH |
| 國家衛生研究院 |
2024-06-24 |
Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment
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Li, MC;Lai, YL;Kuo, PH;Reddy, JS;Chen, CM;Manimala, J;Wang, PC;Wu, MS;Chang, CY;Yang, CM;Lin, CY;Huang, YC;Chiu, CH;Chang, L;Lin, WH;Yeh, TK;Yen, WC;Hsieh, HP |
| 國家衛生研究院 |
2024-06-18 |
Method of the preparation of fused multicyclic compounds
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Hsieh, HP |
| 國家衛生研究院 |
2024-05-09 |
Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function
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Lee, HW;Chen, SJ;Tsai, KJ;Hsu, KS;Chen, YF;Chang, CH;Lin, HH;Hsueh, WY;Hsieh, HP;Lee, YF;Chiang, HC;Chang, JY |
| 國家衛生研究院 |
2024-04-26 |
The method of the preparation of fused multicyclic compounds
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Hsieh, HP |
| 國家衛生研究院 |
2023-10-05 |
A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects
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Hsu, YT;Chen, SR;Chang, YC;Chang, HF;Yeh, TK;Chuang, JY;Loh, HH;Hsieh, HP;Ueng, SH;Yeh, SH |
| 國家衛生研究院 |
2023-10 |
Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs
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Hsieh, HP;Li, MC;Yen, WC;Hsu, JTA;Yeh, TK;Li, WS;Wu, HC |
| 國家衛生研究院 |
2023-09-22 |
Influence of ring strain on the formation of rearrangement vs cyclization isotwistane products in the acyl radical reaction of bicyclo[2.2.2]octanone
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Chen, CM;Lin, SK;Hsieh, CT;Reddy, JS;Teoh, YN;Cheng, MJ;Hsieh, HP |
| 國家衛生研究院 |
2023-02-07 |
Development of furanopyrimidine-based orally active third- generation EGFR inhibitors for the treatment of non-small cell lung cancer
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Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP |
| 國家衛生研究院 |
2022-09-12 |
A critical overview of current progress for COVID-19: Development of vaccines, antiviral drugs, and therapeutic antibodies
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Kumari, M;Lu, RM;Li, MC;Huang, JL;Hsu, FF;Ko, SH;Ke, FY;Su, SC;Liang, KH;Yuan, JPY;Chiang, HL;Sun, CP;Lee, IJ;Li, WS;Hsieh, HP;Tao, MH;Wu, HC |
| 國家衛生研究院 |
2022-08-09 |
Recent advances in total synthesis of natural products by masked ortho-benzoquinones
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Chen, CM;Hsieh, HP |
| 國家衛生研究院 |
2022-05-09 |
Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer
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Liu, JS;Fang, WK;Yang, SM;Wu, MC;Chen, TJ;Chen, CM;Lin, TY;Liu, KL;Wu, CM;Chen, YC;Chuu, CP;Wang, LY;Hsieh, HP;Kung, HJ;Wang, WC |
| 國家衛生研究院 |
2022-04-06 |
Identification of entry inhibitors against delta and omicron variants of SARS-CoV-2
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Lee, RKL;Li, TN;Chang, SY;Chao, TL;Kuo, CH;Pan, MYC;Chiou, YT;Liao, KJ;Yang, Y;Wu, YH;Huang, CH;Juan, HF;Hsieh, HP;Wang, LHC |
| 國家衛生研究院 |
2022-02-07 |
Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer
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Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP |
| 國家衛生研究院 |
2022-01-21 |
Novel FLT3/AURK multikinase inhibitor is efficacious against sorafenib-refractory and sorafenib-resistant hepatocellular carcinoma
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Lai, YL;Wang, KH;Hsieh, HP;Yen, WC |
| 國家衛生研究院 |
2021-10-04 |
Discovery of BPR1R024, an orally active and selective CSF1R inhibitor that exhibits antitumor and immunomodulatory activity in a murine colon tumor model
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Lee, KH;Yen, WC;Lin, WH;Wang, PC;Lai, YL;Su, YC;Chang, CY;Wu, CS;Huang, YC;Yang, CM;Chou, LH;Yeh, TK;Chen, CT;Shih, C;Hsieh, HP |
| 國家衛生研究院 |
2021-07-16 |
Colloidal assemblies composed of polymeric micellar/emulsified systems integrate cancer therapy combining a tumor-associated antigen vaccine and chemotherapeutic regimens
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Huang, CY;Lin, SY;Hsu, TA;Hsieh, HP;Huang, MH |
| 國家衛生研究院 |
2021-06-29 |
Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization
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Li, MC;Lin, WH;Wang, PC;Su, YC;Chen, PY;Fan, CM;Chen, CP;Huang, CL;Chiu, CH;Chang, L;Chen, CT;Yeh, TK;Hsieh, HP |
| 國家衛生研究院 |
2021-04-16 |
Development of a robust scale-up synthetic route for BPR1K871: A clinical candidate for the treatment of acute myeloid leukemia and solid tumors
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Reddy, JS;Chen, CM;Coumar, MS;Sun, HY;Sun, N;Hsieh, HP |
| 國家衛生研究院 |
2021-04-13 |
Chlorinated briarane diterpenoids from octocoral Briareum stechei (Kükenthal, 1908)
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Huynh, TH;Lee, GH;Tanaka, J;Hsieh, HP;Kelvin Tsou, L;Zhang, MM;Kuo, TJ;Wen, ZH;Lu, CK;Sung, PJ |
| 國家衛生研究院 |
2021-02-22 |
Mimicking H3 substrate arginine in the design of G9a lysine methyltransferase inhibitors for cancer therapy: A computational study for structure-based drug design
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Chandar Charles, MR;Li, MC;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2021-01-31 |
Briarenols W-Z: Chlorine-containing polyoxygenated briaranes from octocoral briareum stechei (Kükenthal, 1908)
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Chen, YY;Zhang, YL;Lee, GH;Tsou, LK;Zhang, MM;Hsieh, HP;Chen, JJ;Ko, CY;Wen, ZH;Sung, PJ |
| 國家衛生研究院 |
2021-01-15 |
One-pot synthesis of dibenzo[b,f]oxepines and total synthesis of bauhinoxepin C
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Taweesak, P;Thongaram, P;Kraikruan, P;Thanetchaiyakup, A;Chuanopparat, N;Hsieh, HP;Uang, BJ;Ngernmeesri, P |
| 中山醫學大學 |
2021 |
Chlorinated briarane diterpenoids from octocoral Briareum stechei (Kukenthal, 1908)
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Huynh, TH; Lee, GH; Tanaka, J; Hsieh, HP; Tsou, LK; Zhang, MZM; Kuo, TJ; Wen, ZH; Lu, CK; Sung, PJ |
| 國家衛生研究院 |
2020-12-10 |
Tumor-agnostic inhibitors in oncology: A new phase for precision medicine
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Li, MC;Hsieh, HP |
| 國家衛生研究院 |
2020-07-07 |
Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors
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Syed, SB;Lin, SY;Arya, H;Fu, IH;Yeh, TK;Charles, MRC;Periyasamy, L;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2020-05 |
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors
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Lin, SY;Chang, CF;Coumar, MS;Chen, PY;Kuo, FM;Chen, CH;Li, MC;Lin, WH;Kuo, PC;Wang, SY;Li, AS;Lin, CY;Yang, CM;Yeh, TK;Song, JS;Hsu, JTA;Hsieh, HP |
| 國家衛生研究院 |
2020-03-01 |
A selective Aurora-A 5'-UTR siRNA inhibits tumor growth and metastasis
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Lai, CH;Chen, RY;Hsieh, HP;Tsai, SJ;Chang, KC;Yen, CJ;Huang, YC;Liu, YW;Lee, JC;Lai, YC;Hung, LY;Lin, BW |
| 國家衛生研究院 |
2020-01 |
Identification of novel quinoline inhibitor for EHMT2/G9a through virtual screening
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Chandar Charles, MR;Mahesh, A;Lin, SY;Hsieh, HP;Dhayalan, A;Coumar, MS |
| 國家衛生研究院 |
2019-10-08 |
Identification of two novel small compounds that inhibit liver cancer formation in zebrafish and analysis of their conjugation to nanodiamonds to further reduce toxicity
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Tseng, PH;Sie, ZL;Liu, MC;Lin, HS;Yang, WY;Lin, TY;Hsieh, HP;Hung, SC;Cheng, CL;Wang, HD;Chang, HH;Yuh, CH |
| 國家衛生研究院 |
2019-10 |
The molecular mechanisms of EpCAM in regulating tumor progression and development of anti-EpCAM antibodies for colon cancer diagnosis and therapy
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Wu, HC;Liang, KH;Hsieh, HP;Li, WS |
| 國家衛生研究院 |
2019-10 |
Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer
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Hsieh, HP;Chang, JY;Yeh, CT;Lin, SY;Ke, YY;Lin, WH;Hsu, TA;Wu, SY;Yeh, TK |
| 國家衛生研究院 |
2019-09-28 |
Design of drug-like hepsin inhibitors against prostate cancer and kidney stones
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Blay, V;Li, MC;Ho, SP;Stoller, ML;Hsieh, HP;Houston, DR |
| 國家衛生研究院 |
2019-09-27 |
Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer
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Lin, SY;Chang Hsu, Y;Peng, YH;Ke, YY;Lin, WH;Sun, HY;Shiao, HY;Kuo, FM;Chen, PY;Lien, TW;Chen, CH;Chu, CY;Wang, SY;Yeh, KC;Chen, CP;Hsu, TA;Wu, SY;Yeh, TK;Chen, CT;Hsieh, HP |
| 國家衛生研究院 |
2019-09 |
Design of a potent anticancer lead inspired by natural products from traditional Indian medicine
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Arya, H;Yadav, CS;Lin, SY;Syed, SB;Charles, MRC;Kannadasan, S;Hsieh, HP;Singh, SS;Gajurel, PR;Coumar, MS |
| 國家衛生研究院 |
2019-07-21 |
Lysosomal cysteine protease cathepsin S is involved in cancer cell motility by regulating store-operated Ca(2+) entry
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Lin, HH;Chen, SJ;Shen, MR;Huang, YT;Hsieh, HP;Lin, SY;Lin, CC;Chang, WW;Chang, JY |
| 國家衛生研究院 |
2019-07 |
Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation
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Quattrini, L;Coviello, V;Sartini, S;Di Desidero, T;Orlandi, P;Ke, YY;Liu, KL;Hsieh, HP;Bocci, G;La Motta, C |
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