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Institution Date Title Author
國家衛生研究院 2025-07-25 Noncovalent interaction effects on the acyl radical reaction of bicyclo 2.2.2 octanone: Selective formation of rearrangement and cyclization products Chen, CM;Kuo, TC;Reddy, JS;Teoh, YN;Huang, JS;Lin, SK;Cheng, MJ;Hsieh, HP
國家衛生研究院 2025-07-24 Unraveling Cathepsin S regulation in interleukin-7-mediated anti-tumor immunity reveals its targeting potential against oral cancer Chang, YC;Chen, SJ;Chen, SH;Hsiao, SY;Chen, LH;Chen, CH;Liu, CC;Chen, YW;Liu, KJ;Wu, SY;Chu, JM;Qiu, LY;Chiang, WF;Hsieh, HP;Hsueh, WY;Hsiao, JR;Shen, MR;Chang, JY;Chang, KY
國家衛生研究院 2025-05-20 Structure-based design of potent and selective merTK inhibitors by modulating the conformation of alphaC helix Peng, YH;Li, MC;Yen, WC;Yeh, TK;Hsueh, CC;Kuo, FM;Lai, YL;Chang, L;Lee, LC;Chen, PY;Yen, KJ;Chang, TY;Sun, HY;Chang, CY;Hsieh, SH;Yang, CM;Hsieh, HP;Wu, SY
國家衛生研究院 2025-03-25 KIF2C promotes paclitaxel resistance by depolymerizing polyglutamylated microtubules Pao, YS;Liao, KJ;Shiau, YC;Chao, MH;Li, MC;Lin, LM;Chang, HH;Yeh, HW;Chen, YJ;Chiu, YT;Pan, MY;Chang, YH;Shen, SY;Lin, SY;Cheng, HC;Lin, YC;Sun, YJ;Kuo, CC;Hsieh, HP;Wang, LH
國家衛生研究院 2025-03-24 Identification and biological evaluation of a novel CLK4 inhibitor targeting alternative splicing in pancreatic cancer using structure-based virtual screening Yang, CL;Wu, YW;Tu, HJ;Yeh, YH;Lin, TE;Sung, TY;Li, MC;Yen, SC;Hsieh, JH;Yu, MC;Hsieh, SY;Hsieh, HP;Pan, SL;Hsu, KC
國家衛生研究院 2025-01 Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models Tang, YC;Ou, JJ;Hsu, SC;Huang, CH;Lin, LM;Chang, HH;Wang, YH;Huang, ZT;Sun, M;Liu, KJ;Hung, YM;Lai, CY;Shih, C;Chen, CT;Chang, JY;Hsieh, HP;Jiaang, WT;Kuo, CC
國家衛生研究院 2025-01 Aldehyde dehydrogenases as drug targets for cancer: SAR and structural biology aspects for inhibitor design Tahiliani, H;Dhayalan, A;Li, MC;Hsieh, HP;Coumar, MS
國家衛生研究院 2024-12-30 Novel naphthyridones targeting pannexin 1 for colitis management Hsueh, WY;Wu, YL;Weng, MT;Liu, SY;Santavanond, JP;Liu, YC;Lin, C;Lai, CN;Lu, YR;Hsu, JY;Gao, HY;Lee, JC;Wei, SC;Lyu, PC;Poon, IKH;Hsieh, HP;Chiu, YH
國家衛生研究院 2024-12 Discovery of novel TANK-Binding Kinase 1 (TBK1) inhibitor against pancreatic ductal adenocarcinoma Shih, WH;Huang, HL;HuangFu, WC;Lin, TE;Sung, TY;Li, MC;Huang, GL;Chang, YW;Yen, SC;Hsieh, HP;Hsu, KC;Pan, SL
國家衛生研究院 2024-11-07 Novel approach to anti-tumour and anti-SARS-COV-2 drugs by modulating sialylation of N-glycans Li, WS;Perez, SJL;Chang, TT;Chen, CL;Wang, SH;Li, CW;Hsieh, HP;Wu, HC
國家衛生研究院 2024-11-07 Discovery of DYRK1A inhibitors as potential treatment of pancreatic ductal adenocarcinoma (PDAC) Hsieh, HP;Zhang-Jian, YX;Hsu, KC;Pan, SL;Li, WS;Wu, HC
國家衛生研究院 2024-11 DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration Lin, SY;Chang, YC;Tien, YW;Kuo, YH;Chang, HF;Ou, LC;Chen, YP;Chang, KH;Hsu, YT;Huang, YC;Yang, CM;Law, PY;Xi, JH;Tao, PL;Loh, HH;Yeh, TK;Zhuang, H;Hsieh, HP;Shih, C;Chen, CT;Yeh, SH;Ueng, SH
國家衛生研究院 2024-11 Epithelial cell adhesion molecule induces induces Wnt receptor transcription to promote colorectal cancer progression Wu, HC;Panda, SS;Lee, CC;Shen, CN;Li, WS;Hsieh, HP
國家衛生研究院 2024-06-24 Macrophage-mediated controlled release of cysteine protease inhibitor from PLGA-PEG/hydroxyapatite microspheres for targeting cathepsin S in Alzheimer's disease Yang, IH;Kuan, CY;Zhang, SL;Chen, ZY;Li, CH;Liang, YJ;Kuo, WT;Chang, CT;Lin, J;Hsieh, HP;Chang, JY;Lin, FH
國家衛生研究院 2024-06-24 Discovery of dual MER/AXL kinase inhibitors as bifunctional small molecules for inhibiting tumor growth and enhancing tumor immune microenvironment Li, MC;Lai, YL;Kuo, PH;Reddy, JS;Chen, CM;Manimala, J;Wang, PC;Wu, MS;Chang, CY;Yang, CM;Lin, CY;Huang, YC;Chiu, CH;Chang, L;Lin, WH;Yeh, TK;Yen, WC;Hsieh, HP
國家衛生研究院 2024-06-18 Method of the preparation of fused multicyclic compounds Hsieh, HP
國家衛生研究院 2024-05-09 Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function Lee, HW;Chen, SJ;Tsai, KJ;Hsu, KS;Chen, YF;Chang, CH;Lin, HH;Hsueh, WY;Hsieh, HP;Lee, YF;Chiang, HC;Chang, JY
國家衛生研究院 2024-04-26 The method of the preparation of fused multicyclic compounds Hsieh, HP
國家衛生研究院 2023-10-05 A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects Hsu, YT;Chen, SR;Chang, YC;Chang, HF;Yeh, TK;Chuang, JY;Loh, HH;Hsieh, HP;Ueng, SH;Yeh, SH
國家衛生研究院 2023-10 Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs Hsieh, HP;Li, MC;Yen, WC;Hsu, JTA;Yeh, TK;Li, WS;Wu, HC
國家衛生研究院 2023-09-22 Influence of ring strain on the formation of rearrangement vs cyclization isotwistane products in the acyl radical reaction of bicyclo[2.2.2]octanone Chen, CM;Lin, SK;Hsieh, CT;Reddy, JS;Teoh, YN;Cheng, MJ;Hsieh, HP
國家衛生研究院 2023-02-07 Development of furanopyrimidine-based orally active third- generation EGFR inhibitors for the treatment of non-small cell lung cancer Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2022-09-12 A critical overview of current progress for COVID-19: Development of vaccines, antiviral drugs, and therapeutic antibodies Kumari, M;Lu, RM;Li, MC;Huang, JL;Hsu, FF;Ko, SH;Ke, FY;Su, SC;Liang, KH;Yuan, JPY;Chiang, HL;Sun, CP;Lee, IJ;Li, WS;Hsieh, HP;Tao, MH;Wu, HC
國家衛生研究院 2022-08-09 Recent advances in total synthesis of natural products by masked ortho-benzoquinones Chen, CM;Hsieh, HP
國家衛生研究院 2022-05-09 Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer Liu, JS;Fang, WK;Yang, SM;Wu, MC;Chen, TJ;Chen, CM;Lin, TY;Liu, KL;Wu, CM;Chen, YC;Chuu, CP;Wang, LY;Hsieh, HP;Kung, HJ;Wang, WC

Showing items 1-25 of 265  (11 Page(s) Totally)
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