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Showing items 201-250 of 265  (6 Page(s) Totally)
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Institution Date Title Author
國家衛生研究院 2008-05-01 抗腫瘤化合物 Hsieh, HP;Liou, JP;Chang, JY;Tung, YS;Chao, YS
國家衛生研究院 2008-05 Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana Chou, YC; Prakash, E; Huang, CF; Lien, TW; Chen, X; Su, IJ; Chao, YS; Hsieh, HP; Hsu, JTA
國家衛生研究院 2008-04-15 Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus Chou, CY; Chien, CH; Han, YS; Prebanda, MT; Hsieh, HP; Turk, B; Chang, GG; Chen, X
國家衛生研究院 2008-03-13 Synthesis and biological evaluation of 1-methyl-2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors Romagnoli, R; Baraldi, PG; Sarkar, T; Carrion, MD; Cara, CL; Cruz-Lopez, O; Preti, D; Tabrizi, MA; Tolomeo, M; Grimaudo, S; Di Cristina, A; Zonta, N; Balzarini, J; Brancale, A; Hsieh, HP; Hamel, E
國家衛生研究院 2008-03-10 Reactions of 2-hydroxybenzophenones with Corey-Chaykovsky reagent Chittimalla, SK; Chang, TC; Liu, TC; Hsieh, HP; Liao, CC
國家衛生研究院 2008-03-01 Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold Coumar, MS; Wu, JS; Leou, JS; Tan, UK; Chang, CY; Chang, TY; Lin, WH; Hsu, JTA; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2008-02-11 一種抗病毒之醫藥組合物 Hsu, TA;Hsieh, HP;Juan, LJ;Chang, SY;Kuo, YH
國家衛生研究院 2008-02-07 First total syntheses of (+/-)-annuionone B and (+/-)-tanarifuranonol Shiao, HY; Hsieh, HP; Liao, CC
國家衛生研究院 2008-02 A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells Kao, YH; Hsieh, HP; Chitlimalla, SK; Pan, WY; Kuo, CC; Tsai, YC; Lin, WH; Chuang, SE; Chang, JY
臺北醫學大學 2008 Discovery of 4-Amino and 4-Hydroxy-1-Aroylindoles as Potent Tubulin Polymerization Inhibitors 劉景平; Liou JP; Wu ZY; Kuo CC; Chang CY; Lu PY; Chen CM; Hsieh HP; Chang JY
臺北醫學大學 2008 Synthesis and Structure-Activity Relationships of 2-Amino and 2-Hydroxy-1-Aroylnaphthalenes as Potent Antitubulin Agents 劉景平; Reddy GR; Kuo CC; Tan UK; Coumar MS; Chang CY; Lai MJ; Wu SY; Chang JY; Liou JP; Hsieh HP
國立臺灣大學 2008 Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus Chou CY; Chien CH; Han YS; Prebanda MT; Hsieh HP; Turk B; Chang GG; Chen X
國家衛生研究院 2007-12 Strategies of development of antiviral agents directed against influenza virus replication Hsieh, HP;Hsu, JTA
國家衛生研究院 2007-09-06 4-and 5-aroylindoles as novel classes of potent antitubulin agents Liou, JP; Wu, CY; Hsieh, HP; Chang, CY; Chen, CM; Kuo, CC; Chang, JY
國家衛生研究院 2007-07-31 Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil Chen, CC; Chen, LT; Tsou, TC; Pan, WY; Kuo, CC; Liu, JF; Yeh, SC; Tsai, FY; Hsieh, HP; Chang, JY
國家衛生研究院 2007-07 Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes Yao, HT; Wu, YS; Chang, YW; Hsieh, HP; Chen, WC; Lan, SJ; Chen, CT; Chao, YS; Chang, L; Sun, HY; Yeh, TK
國家衛生研究院 2007-07 Anti-influenza drug discovery Hsu, JTA;Hsieh, HP;Hung, HC;Ju, YW;Tseng, SN;Tseng, CP;Yang, JM;Chang, CW;Fang, MY;Lin, CC;Homg, JT;Shih, SR;Chao, YS
國家衛生研究院 2007-07 From bench to drug candidate: Design and synthesis of 5,6-fused heteroaromatics as anticancer agents Hsieh, HP
國立臺灣大學 2007-04 Urine sediment examination: a comparison of automated urinalysis systems and manual microscopy. Chien, TI; Kao, JT; Liu, HL; Lin, PC; Hong, JS; Hsieh, HP; Chien, MJ.
國家衛生研究院 2007-03-01 3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes Coumar, MS; Chang, CN; Chen, CT; Chen, X; Chien, CH; Tsai, TY; Cheng, JH; Wu, HY; Han, CH; Wu, SH; Huang, YW; Hsu, T; Hsu, LJ; Chao, YS; Hsieh, HP; Jiaang, WT
國家衛生研究院 2007-02-08 Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells Chen, CN; Huang, HH; Wu, CL; Lin, CPC; Hsu, JTA; Hsieh, HP; Chuang, SE; Lai, GM
國家衛生研究院 2007-02-01 Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study Chang, YW; Chen, WC; Lin, KT; Chang, L; Yao, HT; Hsieh, HP; Lan, SJ; Chen, CT; Chao, YS; Yeh, TK
臺北醫學大學 2007 Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells. 賴基銘; Chen CN; Huang HH; Wu CL; Lin CP; Hsu JT; Hsieh HP; Chuang SE; Lai GM
臺北醫學大學 2007 4- and 5-Aroylindoles as Novel Classes of Potent Antitubulin Agents. 劉景平; Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
國家衛生研究院 2006-12 Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats Chang, YW; Yeh, TK; Lin, KT; Chen, WC; Yao, HT; Lan, SJ; Wu, YS; Hsieh, HP; Chen, CM; Chen, CT
國家衛生研究院 2006-11-16 7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents Chang, JY; Hsieh, HP; Chang, CY; Hsu, KS; Chiang, YF; Chen, CM; Kuo, CC; Liou, JP
國家衛生研究院 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists Mahindroo, N; Peng, YH; Lin, CH; Tan, UK; Prakash, E; Lien, TW; Lu, IL; Lee, HJ; Hsu, JTA; Chen, X; Liao, CC; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-10 Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents Liou, JP;Mahindroo, N;Chang, CW;Guo, FM;Lee, SWH;Tan, UK;Yeh, TK;Kuo, CC;Chang, YW;Lu, PH;Tung, YS;Lin, KT;Chang, JY;Hsieh, HP
國家衛生研究院 2006-09 MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes Hsieh, HP;Coumar, MS;Chang, CN;Wu, SH;Chen, X;Chen, CT;Jiaang, WT
國家衛生研究院 2006-08-24 Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease Lu, IL; Mahindroo, N; Liang, PH; Peng, YH; Kuo, CJ; Tsai, KC; Hsieh, HP; Chao, YS; Wu, SY
國家衛生研究院 2006-07 Antiviral drug discovery against SARS-CoV Wu, YS;Lin, WH;Hsu, JTA;Hsieh, HP
國家衛生研究院 2006-06-15 Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies Tsai, KC; Chen, SY; Liang, PH; Lu, IL; Mahindroo, N; Hsieh, HP; Chao, YS; Liu, L; Liu, D; Lien, W; Lin, TH; Wu, SY
國家衛生研究院 2006-06-15 Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors Tsai, TY; Coumar, MS; Hsu, T; Hsieh, HP; Chien, CH; Chen, CT; Chang, CN; Lo, YK; Wu, SH; Huang, CY; Huang, YW; Wang, MH; Wu, HY; Lee, HJ; Chen, X; Chao, YS; Jiaang, WT
國家衛生研究院 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities Lu, IL; Huang, CF; Peng, YH; Lin, YT; Hsieh, HP; Chen, CT; Lien, TW; Lee, HJ; Mahindroo, N; Prakash, E; Yueh, A; Chen, HY; Goparaju, CMV; Chen, X; Liao, CC; Chao, YS; Hsu, JTA; Wu, SY
國家衛生研究院 2006-05 Antitubulin agents for the treatment of cancer - a medicinal chemistry update Mahindroo, N; Liou, JP; Chang, JY; Hsieh, HP
國家衛生研究院 2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies Mahindroo, N; Wang, CC; Liao, CC; Huang, CF; Lu, IL; Lien, TW; Peng, YH; Huang, WJ; Lin, YT; Hsu, MC; Lin, CH; Tsai, CH; Hsu, JTA; Chen, X; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-01-12 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Tsu, H; Chen, X; Chen, CT; Lee, SJ; Chang, CN; Kao, KH; Coumar, MS; Yeh, YT; Chien, CH; Wang, HS; Lin, KT; Chang, YY; Wu, SH; Chen, YS; Lu, IL; Wu, SY; Tsai, TY; Chen, WC; Hsieh, HP; Chao, YS; Jiaang, WT
國家衛生研究院 2006-01-01 Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system Hwang, DR;Wu, YS;Chang, CW;Lien, TW;Chen, WC;Tan, UK;Hsu, JTA;Hsieh, HP
臺北醫學大學 2006 7-Aroyl-aminoindoline-1-sulfonamides as a Novel Class of Potent Antitubulin Agents 劉景平; 陳繼明; Chang JY; Hsieh HP; Chang CY; Hsu KS; Chiang YF; Chen CM; Kuo CC; Liou JP*
臺北醫學大學 2006 Antitubulin agents for the treatment of cancer-a medicinal chemistry update 劉景平; Mahindroo N; Liou JP; Chang JY; Hsieh HP
國家衛生研究院 2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities Mahindroo, N; Huang, CF; Peng, YH; Wang, CC; Liao, CC; Lien, TW; Chittimalla, SK; Huang, WJ; Chai, CH; Prakash, E; Chen, CP; Hsu, TA; Peng, CH; Lu, IL; Lee, LH; Chang, YW; Chen, WC; Chou, YC; Chen, CT; Goparaju, CMV; Chen, YS; Lan, SJ; Yu, MC; Chen, X; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2005-08-23 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2005-05 Shear stress inhibits smooth muscle cell-induced inflammatory gene expression in endothelial cells - Role of NF-kappa B Chiu, JJ; Chang, SF; Lee, PL; Lee, CI; Tsai, MC; Lee, DY; Hsieh, HP; Usami, S; Chien, S
國家衛生研究院 2005-05 Pharmaceutical design of antimitotic agents based on combretastatins Hsieh, HP;Liou, JP;Mahindroo, N
國家衛生研究院 2005-03 Promazine analogues as potential anti SARS-CoV drugs Hsieh, HP;Wu, YS;Lu, PH;Chen, CM;Chao, YC;Jan, JT;Huei-Ru, L;Ma, SH;Chao, YS;Hsu, TA
國家衛生研究院 2005-03 Design, synthesis and sar of indole-based PPAR agonists Hsieh, HP;Mahindroo, N;Coumar, MS;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Lin, YT;Lee, LH;Prakash, E;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Chao, YS
國家衛生研究院 2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents Hsieh, HP;Mahindroo, N;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Peng, YH;Lee, LH;Prakash, E;Chen, WC;Chang, YW;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Lan, SJ;Chao, YS
國家衛生研究院 2005 Inhibition of SARS-CoV 3C-like protease activity by theaflavin-3,3 '- digallate (TF3) Chen, CN; Lin, CPC; Huang, KK; Chen, WC; Hsieh, HP; Liang, PH; Hsu, JTA
國家衛生研究院 2004-09-10 Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV Hsu, JTA; Kuo, CJ; Hsieh, HP; Wang, YC; Huang, KK; Lin, CPC; Huang, PF; Chen, X; Liang, PH
國家衛生研究院 2004-09 Drug design of BPR0L075 as an anticancer agent Hsieh, HP;Liou, JP;Chang, CW;Kuo, CC;Chang, YL;Kuo, FM;Tseng, HY;Pan, WY;Chen, CP;Yang, YN;Chen, CT;Lee, SJ;Chang, JY

Showing items 201-250 of 265  (6 Page(s) Totally)
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