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"hsieh hp"的相关文件
显示项目 131-180 / 265 (共6页)
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| 國家衛生研究院 |
2012-01 |
A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors
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Lin, WH;Song, JS;Lien, TW;Chang, CY;Wu, SH;Huang, YW;Chang, TY;Fang, MY;Yen, KJ;Chen, CH;Chu, CY;Hsieh, HP;Chen, YR;Chao, YS;Hsu, JT |
| 國家衛生研究院 |
2011-11-15 |
Coumarin compounds and their use for treating cancer
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Hsieh, HP;Chang, JY;Kuo, CC;Chao, YS |
| 國家衛生研究院 |
2011-09-23 |
BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo
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Hsieh, HP;Cheung, CHA;Lin, WH;Hsu, TA;Coumar, MS;Chao, YS;Chang, JY |
| 國家衛生研究院 |
2011-09 |
Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents
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Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP |
| 國家衛生研究院 |
2011-09 |
Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway
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Lin, PH;Ke, YY;Su, CT;Shiao, HY;Hsieh, HP;Chao, YK;Lee, CN;Kao, CL;Chao, YS;Chang, SY |
| 國家衛生研究院 |
2011-08 |
BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells
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Cheung, CH;Lin, WH;Hsu, TA;Hour, TC;Yeh, TK;Ko, S;Lien, TW;Coumar, MS;Liu, JF;Lai, WY;Shiao, HY;Lee, TR;Hsieh, HP;Chang, JY |
| 國家衛生研究院 |
2011-07-11 |
抑制C型肝炎病毒感染之倍半帖內酯類化合物及其醫藥組成物
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Hsieh, HP;Hsu, TA;Hwang, DR |
| 國家衛生研究院 |
2011-06-21 |
抑制冠狀病毒之醫藥組合物
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Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW |
| 國家衛生研究院 |
2011-06-21 |
抑制冠狀病毒之醫藥組合物
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Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW |
| 國家衛生研究院 |
2011-06-21 |
抑制冠狀病毒之醫藥組合物
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Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW |
| 國家衛生研究院 |
2011-06 |
Aurora kinase inhibitor patents and agents in clinical testing: an update (2009-10)
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Cheung, CHA;Coumar, MS;Chang, JY;Hsieh, HP |
| 國家衛生研究院 |
2011-04-28 |
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-Fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents
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Tung, YS;Coumar, MS;Wu, YS;Shiao, HY;Chang, JY;Liou, JP;Shukla, P;Chang, CW;Chang, CY;Kuo, CC;Yeh, TK;Lin, CY;Wu, JS;Wu, SY;Liao, CC;Hsieh, HP |
| 國家衛生研究院 |
2011-04-06 |
Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis related disorders
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Hsieh, HP;Chang, JY;Liou, JP;Chang, CW |
| 國家衛生研究院 |
2011-04 |
Antivascular activities of novel tubulin binding agent BPR0L075
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Liu, XL;Liu, L;Beck, H;Hsieh, HP;Boreddy, S;Srivastava, S;Mason, RP |
| 國家衛生研究院 |
2011-03-27 |
Design and synthesis of potent Aurora kinase inhibitors
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Chu, CY;Mohane, CS;Hsu, JTA;Yeh, TK;Chen, CT;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2011-03-07 |
2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors
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Chuang, HY;Chang, JY;Lai, MJ;Kuo, CC;Lee, HY;Hsieh, HP;Chen, YJ;Chen, LT;Pan, WY;Liou, JP |
| 國家衛生研究院 |
2011-03 |
Potent EGFR tyrosine kinase inhibitors as anticancer agents
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Shiao, HY;Chu, CY;Hsu, JTA;Yeh, TK;Hsieh, HP |
| 國家衛生研究院 |
2011-03 |
SAR studies of quinoline derivatives as novel anti-influenza agents
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Ko,SK;Yeh, JY;Horng, JT;Hsu, TA;Hsieh HP |
| 高雄醫學大學 |
2011 |
2-amino-3,4,5-trimethoxybenzophenones as potent tubulin polymerization inhibitors.
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陳立宗; Chuang HY;Chang JY;Lai MJ;Kuo CC;Lee HY;Hsieh HP;Chen YJ;Chen LT;Pan WY;Liou JP. |
| 臺北醫學大學 |
2011 |
2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors
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Chuang, HY;Chang, JY;Lai, MJ;Kuo, CC;Lee, HY;Hsieh, HP;Chen, YJ;Chen, LT;Pan, WY;Liou, JP |
| 臺北醫學大學 |
2011 |
Synthesis and Biological Evaluation of 1-(4’-Indolyl and 6’-Quinolinyl)indoles as a New Class of Potent Anticancer Agents
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Lia, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP |
| 臺北醫學大學 |
2011 |
Synthesis and biological evaluation of 1-(40-Indolyl and 60-Quinolinyl) indoles as a new class of potent anticancer agents.
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Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey;KS;Liou, JP |
| 國家衛生研究院 |
2010-12-01 |
吲哚化合物
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Hsieh, HP;Mahindroo, N;Hsu, TA;Huang, CF;Chen, X;Chao, YS |
| 國家衛生研究院 |
2010-12-01 |
抗肿瘤化合物
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Hsieh, HP;Chao, YS;Liou, JP;Chang, JY;Tung, YS |
| 國家衛生研究院 |
2010-10-28 |
Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency
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Wu, CH;Coumar, MS;Chu, CY;Lin, WH;Chen, YR;Chen, CT;Shiao, HY;Rafi, S;Wang, SY;Hsu, H;Chen, CH;Chang, CY;Chang, TY;Lien, TW;Fang, MY;Yeh, KC;Chen, CP;Yeh, TK;Hsieh, SH;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2010-10-06 |
吡咯烷化合物
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Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS |
| 國家衛生研究院 |
2010-10 |
Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists
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Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY |
| 國家衛生研究院 |
2010-09 |
Cancer cells acquire mitotic drug resistance properties through beta i-tubulin mutations and alterations in the expression of beta-tubulin isotypes
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Cheung, CHA;Wu, SY;Lee, TR;Chang, CY;Wu, JS;Hsieh, HP;Chang, JY |
| 國家衛生研究院 |
2010-08 |
Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models
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Hsieh, HP;Chu, CY;Coumar, MS;Lin, WH;Chen, CT;Hsu, TA;Wu, SY;Chao, YS |
| 國家衛生研究院 |
2010-07 |
Antiangiogenic Activities and Cisplatin-combined Antitumor Activities of BPR0L075
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Chen, CP;Hu, CB;Yeh, KC;Song, JS;Yeh, TK;Tung, FF;Hwang, LL;Tseng, HY;Huang, YC;Shy, HS;Hsieh, SH;Shen, CC;Wang, HS;Hsieh, HP;Liou, JP;Chao, YS;Chen, CT |
| 國家衛生研究院 |
2010-06-15 |
Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification
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Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2010-06 |
Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis
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Chen, JC;Uang, BJ;Lyu, PC;Chang, JY;Liu, KJ;Kuo, CC;Hsieh, HP;Wang, HC;Cheng, CS;Chang, YH;Chang, MDT;Chang, WSW;Lin, CC |
| 國家衛生研究院 |
2010-03-30 |
Pyrrolidine compounds
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Jiaang, WT;Chen, X;Wu, SY;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2010-03-11 |
5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors
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Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY |
| 國家衛生研究院 |
2010-02-25 |
Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives
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Yeh, JY;Coumar, MS;Horng, JT;Shiao, HY;Kuo, FM;Lee, HL;Chen, IC;Chang, CW;Tang, WF;Tseng, SN;Chen, CJ;Shih, SR;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2010-02-23 |
Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity
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Shih, SR;Chu, TY;Reddy, GR;Tseng, SN;Chen, HL;Tang, WF;Wu, MS;Yeh, JY;Chao, YS;Hsu, JTA;Hsieh, HP;Horng, JT |
| 國家衛生研究院 |
2010-02-01 |
Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor
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Coumar, MS;Tsai, MT;Chu, CY;Uang, BJ;Lin, WH;Chang, CY;Chang, TY;Leou, JS;Teng, CH;Wu, JS;Fang, MY;Chen, CH;Hsu, JTA;Wu, SY;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2010-02 |
Comparative molecular field analysis of anti-tubulin agents with indole ring binding at the colchicine binding site
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Lin, IH;Hsu, CC;Wang, SH;Hsieh, HP;Sun, YC |
| 國家衛生研究院 |
2010-01 |
BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses
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Shih, SR;Horng, JT;Poon, LL;Chen, TC;Yeh, JY;Hsieh, HP;Tseng, SN;Chiang, C;Li, WL;Chao, YS;Hsu, JT |
| 臺北醫學大學 |
2010 |
5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors
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Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY |
| 國家衛生研究院 |
2009-12-15 |
Indole compounds
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Hsieh, HP;Liou, JP;Chang, JY;Chang, CW |
| 國家衛生研究院 |
2009-12-01 |
芳香羰吲哚化合物
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Hsieh, HP;Liou, JP;Chang, JY;Chang, CW |
| 國家衛生研究院 |
2009-09 |
Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development
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Hsieh, HP;Coumarrs, MS;Chu, CY;Ho, YL;Tsai, MT;Lin, WH;Chen, CH;Song, JS;Hsu, JTA;Chao, YS |
| 國家衛生研究院 |
2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach
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Wu, YS;Coumar, MS;Chang, JY;Sun, HY;Kuo, FM;Kuo, CC;Chen, YJ;Chang, CY;Hsiao, CL;Liou, JP;Chen, CP;Yao, HT;Chiang, YK;Tan, UK;Chen, CT;Chu, CY;Wu, SY;Yeh, TK;Lin, CY;Hsieh, HP |
| 中國醫藥大學 |
2009-08 |
Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach.
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(Wu YS); (Coumar MS); (Chang JY); (Sun HY); (Kuo FM); (Kuo CC); (Chen YJ); (Chang CY); (Hsiao CL); (Liou JP); (Chen CP); 姚賢宗(Hsien-Tsung Yao); (Chiang YK); (Tan UK); (Chen CT); (Chu CY); (Wu SY); (Yeh TK); (Lin CY); (Hsieh HP)* |
| 國家衛生研究院 |
2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity
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Chiang, YK;Kuo, CC;Wu, YS;Chen, CT;Coumar, MS;Wu, JS;Hsieh, HP;Chang, CY;Jseng, HY;Wu, MH;Leou, JS;Song, JS;Chang, JY;Lyu, PC;Chao, YS;Wu, SY |
| 國家衛生研究院 |
2009-07-03 |
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers
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Cheung, CH;Chen, HH;Kuo, CC;Chang, CY;Coumar, MS;Hsieh, HP;Chang, JY |
| 國家衛生研究院 |
2009-06-09 |
Treatment of coronavirus infection
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Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW |
| 國家衛生研究院 |
2009-05-05 |
Indole compounds
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Hsieh, HP;Liou, JP;Chang, JY;Chang, CW |
| 國家衛生研究院 |
2009-05 |
Down-regulation of survivin enhances sensitivity to BPROL075 in human cancer cells via caspase-independent mechanisms
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Cheung, CHA;Chang, CY;Hsieh, HP;Chang, JY |
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