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"hsieh hp"的相关文件
显示项目 206-255 / 265 (共6页)
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| 國家衛生研究院 |
2008-03-01 |
Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold
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Coumar, MS; Wu, JS; Leou, JS; Tan, UK; Chang, CY; Chang, TY; Lin, WH; Hsu, JTA; Chao, YS; Wu, SY; Hsieh, HP |
| 國家衛生研究院 |
2008-02-11 |
一種抗病毒之醫藥組合物
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Hsu, TA;Hsieh, HP;Juan, LJ;Chang, SY;Kuo, YH |
| 國家衛生研究院 |
2008-02-07 |
First total syntheses of (+/-)-annuionone B and (+/-)-tanarifuranonol
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Shiao, HY; Hsieh, HP; Liao, CC |
| 國家衛生研究院 |
2008-02 |
A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells
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Kao, YH; Hsieh, HP; Chitlimalla, SK; Pan, WY; Kuo, CC; Tsai, YC; Lin, WH; Chuang, SE; Chang, JY |
| 臺北醫學大學 |
2008 |
Discovery of 4-Amino and 4-Hydroxy-1-Aroylindoles as Potent Tubulin Polymerization Inhibitors
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劉景平; Liou JP; Wu ZY; Kuo CC; Chang CY; Lu PY; Chen CM; Hsieh HP; Chang JY |
| 臺北醫學大學 |
2008 |
Synthesis and Structure-Activity Relationships of 2-Amino and 2-Hydroxy-1-Aroylnaphthalenes as Potent Antitubulin Agents
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劉景平; Reddy GR; Kuo CC; Tan UK; Coumar MS; Chang CY; Lai MJ; Wu SY; Chang JY; Liou JP; Hsieh HP |
| 國立臺灣大學 |
2008 |
Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus
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Chou CY; Chien CH; Han YS; Prebanda MT; Hsieh HP; Turk B; Chang GG; Chen X |
| 國家衛生研究院 |
2007-12 |
Strategies of development of antiviral agents directed against influenza virus replication
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Hsieh, HP;Hsu, JTA |
| 國家衛生研究院 |
2007-09-06 |
4-and 5-aroylindoles as novel classes of potent antitubulin agents
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Liou, JP; Wu, CY; Hsieh, HP; Chang, CY; Chen, CM; Kuo, CC; Chang, JY |
| 國家衛生研究院 |
2007-07-31 |
Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil
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Chen, CC; Chen, LT; Tsou, TC; Pan, WY; Kuo, CC; Liu, JF; Yeh, SC; Tsai, FY; Hsieh, HP; Chang, JY |
| 國家衛生研究院 |
2007-07 |
Biotransformation of 6-methoxy-3-(3 ',4 ',5 '-trimethoxy-benzoyl)-1-hindole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes
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Yao, HT; Wu, YS; Chang, YW; Hsieh, HP; Chen, WC; Lan, SJ; Chen, CT; Chao, YS; Chang, L; Sun, HY; Yeh, TK |
| 國家衛生研究院 |
2007-07 |
Anti-influenza drug discovery
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Hsu, JTA;Hsieh, HP;Hung, HC;Ju, YW;Tseng, SN;Tseng, CP;Yang, JM;Chang, CW;Fang, MY;Lin, CC;Homg, JT;Shih, SR;Chao, YS |
| 國家衛生研究院 |
2007-07 |
From bench to drug candidate: Design and synthesis of 5,6-fused heteroaromatics as anticancer agents
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Hsieh, HP |
| 國立臺灣大學 |
2007-04 |
Urine sediment examination: a comparison of automated urinalysis systems and manual microscopy.
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Chien, TI; Kao, JT; Liu, HL; Lin, PC; Hong, JS; Hsieh, HP; Chien, MJ. |
| 國家衛生研究院 |
2007-03-01 |
3-[2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-3-methyl-butyramide analogues as selective DPP-IV inhibitors for the treatment of type-II diabetes
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Coumar, MS; Chang, CN; Chen, CT; Chen, X; Chien, CH; Tsai, TY; Cheng, JH; Wu, HY; Han, CH; Wu, SH; Huang, YW; Hsu, T; Hsu, LJ; Chao, YS; Hsieh, HP; Jiaang, WT |
| 國家衛生研究院 |
2007-02-08 |
Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells
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Chen, CN; Huang, HH; Wu, CL; Lin, CPC; Hsu, JTA; Hsieh, HP; Chuang, SE; Lai, GM |
| 國家衛生研究院 |
2007-02-01 |
Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study
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Chang, YW; Chen, WC; Lin, KT; Chang, L; Yao, HT; Hsieh, HP; Lan, SJ; Chen, CT; Chao, YS; Yeh, TK |
| 臺北醫學大學 |
2007 |
Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells.
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賴基銘; Chen CN; Huang HH; Wu CL; Lin CP; Hsu JT; Hsieh HP; Chuang SE; Lai GM |
| 臺北醫學大學 |
2007 |
4- and 5-Aroylindoles as Novel Classes of Potent Antitubulin Agents.
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劉景平; Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY |
| 國家衛生研究院 |
2006-12 |
Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats
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Chang, YW; Yeh, TK; Lin, KT; Chen, WC; Yao, HT; Lan, SJ; Wu, YS; Hsieh, HP; Chen, CM; Chen, CT |
| 國家衛生研究院 |
2006-11-16 |
7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents
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Chang, JY; Hsieh, HP; Chang, CY; Hsu, KS; Chiang, YF; Chen, CM; Kuo, CC; Liou, JP |
| 國家衛生研究院 |
2006-10-19 |
Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists
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Mahindroo, N; Peng, YH; Lin, CH; Tan, UK; Prakash, E; Lien, TW; Lu, IL; Lee, HJ; Hsu, JTA; Chen, X; Liao, CC; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP |
| 國家衛生研究院 |
2006-10 |
Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents
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Liou, JP;Mahindroo, N;Chang, CW;Guo, FM;Lee, SWH;Tan, UK;Yeh, TK;Kuo, CC;Chang, YW;Lu, PH;Tung, YS;Lin, KT;Chang, JY;Hsieh, HP |
| 國家衛生研究院 |
2006-09 |
MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes
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Hsieh, HP;Coumar, MS;Chang, CN;Wu, SH;Chen, X;Chen, CT;Jiaang, WT |
| 國家衛生研究院 |
2006-08-24 |
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease
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Lu, IL; Mahindroo, N; Liang, PH; Peng, YH; Kuo, CJ; Tsai, KC; Hsieh, HP; Chao, YS; Wu, SY |
| 國家衛生研究院 |
2006-07 |
Antiviral drug discovery against SARS-CoV
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Wu, YS;Lin, WH;Hsu, JTA;Hsieh, HP |
| 國家衛生研究院 |
2006-06-15 |
Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies
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Tsai, KC; Chen, SY; Liang, PH; Lu, IL; Mahindroo, N; Hsieh, HP; Chao, YS; Liu, L; Liu, D; Lien, W; Lin, TH; Wu, SY |
| 國家衛生研究院 |
2006-06-15 |
Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors
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Tsai, TY; Coumar, MS; Hsu, T; Hsieh, HP; Chien, CH; Chen, CT; Chang, CN; Lo, YK; Wu, SH; Huang, CY; Huang, YW; Wang, MH; Wu, HY; Lee, HJ; Chen, X; Chao, YS; Jiaang, WT |
| 國家衛生研究院 |
2006-05-04 |
Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities
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Lu, IL; Huang, CF; Peng, YH; Lin, YT; Hsieh, HP; Chen, CT; Lien, TW; Lee, HJ; Mahindroo, N; Prakash, E; Yueh, A; Chen, HY; Goparaju, CMV; Chen, X; Liao, CC; Chao, YS; Hsu, JTA; Wu, SY |
| 國家衛生研究院 |
2006-05 |
Antitubulin agents for the treatment of cancer - a medicinal chemistry update
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Mahindroo, N; Liou, JP; Chang, JY; Hsieh, HP |
| 國家衛生研究院 |
2006-02-09 |
Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies
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Mahindroo, N; Wang, CC; Liao, CC; Huang, CF; Lu, IL; Lien, TW; Peng, YH; Huang, WJ; Lin, YT; Hsu, MC; Lin, CH; Tsai, CH; Hsu, JTA; Chen, X; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP |
| 國家衛生研究院 |
2006-01-12 |
2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV
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Tsu, H; Chen, X; Chen, CT; Lee, SJ; Chang, CN; Kao, KH; Coumar, MS; Yeh, YT; Chien, CH; Wang, HS; Lin, KT; Chang, YY; Wu, SH; Chen, YS; Lu, IL; Wu, SY; Tsai, TY; Chen, WC; Hsieh, HP; Chao, YS; Jiaang, WT |
| 國家衛生研究院 |
2006-01-01 |
Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system
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Hwang, DR;Wu, YS;Chang, CW;Lien, TW;Chen, WC;Tan, UK;Hsu, JTA;Hsieh, HP |
| 臺北醫學大學 |
2006 |
7-Aroyl-aminoindoline-1-sulfonamides as a Novel Class of Potent Antitubulin Agents
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劉景平; 陳繼明; Chang JY; Hsieh HP; Chang CY; Hsu KS; Chiang YF; Chen CM; Kuo CC; Liou JP* |
| 臺北醫學大學 |
2006 |
Antitubulin agents for the treatment of cancer-a medicinal chemistry update
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劉景平; Mahindroo N; Liou JP; Chang JY; Hsieh HP |
| 國家衛生研究院 |
2005-12-29 |
Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities
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Mahindroo, N; Huang, CF; Peng, YH; Wang, CC; Liao, CC; Lien, TW; Chittimalla, SK; Huang, WJ; Chai, CH; Prakash, E; Chen, CP; Hsu, TA; Peng, CH; Lu, IL; Lee, LH; Chang, YW; Chen, WC; Chou, YC; Chen, CT; Goparaju, CMV; Chen, YS; Lan, SJ; Yu, MC; Chen, X; Chao, YS; Wu, SY; Hsieh, HP |
| 國家衛生研究院 |
2005-08-23 |
Indole compounds
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Hsieh, HP;Liou, JP;Chang, JY;Chang, CW |
| 國家衛生研究院 |
2005-05 |
Shear stress inhibits smooth muscle cell-induced inflammatory gene expression in endothelial cells - Role of NF-kappa B
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Chiu, JJ; Chang, SF; Lee, PL; Lee, CI; Tsai, MC; Lee, DY; Hsieh, HP; Usami, S; Chien, S |
| 國家衛生研究院 |
2005-05 |
Pharmaceutical design of antimitotic agents based on combretastatins
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Hsieh, HP;Liou, JP;Mahindroo, N |
| 國家衛生研究院 |
2005-03 |
Promazine analogues as potential anti SARS-CoV drugs
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Hsieh, HP;Wu, YS;Lu, PH;Chen, CM;Chao, YC;Jan, JT;Huei-Ru, L;Ma, SH;Chao, YS;Hsu, TA |
| 國家衛生研究院 |
2005-03 |
Design, synthesis and sar of indole-based PPAR agonists
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Hsieh, HP;Mahindroo, N;Coumar, MS;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Lin, YT;Lee, LH;Prakash, E;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Chao, YS |
| 國家衛生研究院 |
2005-03 |
Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents
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Hsieh, HP;Mahindroo, N;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Peng, YH;Lee, LH;Prakash, E;Chen, WC;Chang, YW;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Lan, SJ;Chao, YS |
| 國家衛生研究院 |
2005 |
Inhibition of SARS-CoV 3C-like protease activity by theaflavin-3,3 '- digallate (TF3)
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Chen, CN; Lin, CPC; Huang, KK; Chen, WC; Hsieh, HP; Liang, PH; Hsu, JTA |
| 國家衛生研究院 |
2004-09-10 |
Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV
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Hsu, JTA; Kuo, CJ; Hsieh, HP; Wang, YC; Huang, KK; Lin, CPC; Huang, PF; Chen, X; Liang, PH |
| 國家衛生研究院 |
2004-09 |
Drug design of BPR0L075 as an anticancer agent
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Hsieh, HP;Liou, JP;Chang, CW;Kuo, CC;Chang, YL;Kuo, FM;Tseng, HY;Pan, WY;Chen, CP;Yang, YN;Chen, CT;Lee, SJ;Chang, JY |
| 國家衛生研究院 |
2004-08-22 |
Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents
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Hsieh, HP;Liou, JP;Chang, YL;Lee, SJ |
| 國家衛生研究院 |
2004-08-12 |
Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents
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Liou, JP; Chang, YL; Kuo, FM; Chang, CW; Tseng, HY; Wang, CC; Yang, YN; Chang, JY; Lee, SJ; Hsieh, HP |
| 國家衛生研究院 |
2004-07-15 |
A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells
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Juang, SH; Pan, WY; Kuo, CC; Liou, JP; Hung, YM; Chen, LT; Hsieh, HP; Chang, JY |
| 國家衛生研究院 |
2004-07-01 |
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo
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Kuo, CC; Hsieh, HP; Pan, WY; Chen, CP; Lion, JP; Lee, SJ; Chang, YL; Chen, LT; Chen, CT; Chang, JY |
| 國家衛生研究院 |
2004-07 |
Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide
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Wu, CJ; Jan, JT; Chen, CM; Hsieh, HP; Hwang, DR; Liu, HW; Liu, CY; Huang, HW; Chen, SC; Hong, CF; Lin, RK; Chao, YS; Hsu, JTA |
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