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机构 日期 题名 作者
國家衛生研究院 2007-02-08 Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells Chen, CN; Huang, HH; Wu, CL; Lin, CPC; Hsu, JTA; Hsieh, HP; Chuang, SE; Lai, GM
國家衛生研究院 2007-02-01 Development and validation of a liquid chromatography-tandem mass spectrometry for the determination of BPR0L075, a novel antimicrotuble agent, in rat plasma: Application to a pharmacokinetic study Chang, YW; Chen, WC; Lin, KT; Chang, L; Yao, HT; Hsieh, HP; Lan, SJ; Chen, CT; Chao, YS; Yeh, TK
臺北醫學大學 2007 Isocostunolide, a sesquiterpene lactone, induces mitochondrial membrane depolarization and caspase-dependent apoptosis in human melanoma cells. 賴基銘; Chen CN; Huang HH; Wu CL; Lin CP; Hsu JT; Hsieh HP; Chuang SE; Lai GM
臺北醫學大學 2007 4- and 5-Aroylindoles as Novel Classes of Potent Antitubulin Agents. 劉景平; Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
國家衛生研究院 2006-12 Pharmacokinetics of anti-SARS-CoV agent niclosamide and its analogs in rats Chang, YW; Yeh, TK; Lin, KT; Chen, WC; Yao, HT; Lan, SJ; Wu, YS; Hsieh, HP; Chen, CM; Chen, CT
國家衛生研究院 2006-11-16 7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents Chang, JY; Hsieh, HP; Chang, CY; Hsu, KS; Chiang, YF; Chen, CM; Kuo, CC; Liou, JP
國家衛生研究院 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists Mahindroo, N; Peng, YH; Lin, CH; Tan, UK; Prakash, E; Lien, TW; Lu, IL; Lee, HJ; Hsu, JTA; Chen, X; Liao, CC; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-10 Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents Liou, JP;Mahindroo, N;Chang, CW;Guo, FM;Lee, SWH;Tan, UK;Yeh, TK;Kuo, CC;Chang, YW;Lu, PH;Tung, YS;Lin, KT;Chang, JY;Hsieh, HP
國家衛生研究院 2006-09 MEDI 416-3- 2-((2S)-2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino -3-methyl-butyr amide analogs as DPP-IV inhibitors for the treatment of type-II diabetes Hsieh, HP;Coumar, MS;Chang, CN;Wu, SH;Chen, X;Chen, CT;Jiaang, WT
國家衛生研究院 2006-08-24 Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease Lu, IL; Mahindroo, N; Liang, PH; Peng, YH; Kuo, CJ; Tsai, KC; Hsieh, HP; Chao, YS; Wu, SY
國家衛生研究院 2006-07 Antiviral drug discovery against SARS-CoV Wu, YS;Lin, WH;Hsu, JTA;Hsieh, HP
國家衛生研究院 2006-06-15 Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies Tsai, KC; Chen, SY; Liang, PH; Lu, IL; Mahindroo, N; Hsieh, HP; Chao, YS; Liu, L; Liu, D; Lien, W; Lin, TH; Wu, SY
國家衛生研究院 2006-06-15 Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors Tsai, TY; Coumar, MS; Hsu, T; Hsieh, HP; Chien, CH; Chen, CT; Chang, CN; Lo, YK; Wu, SH; Huang, CY; Huang, YW; Wang, MH; Wu, HY; Lee, HJ; Chen, X; Chao, YS; Jiaang, WT
國家衛生研究院 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities Lu, IL; Huang, CF; Peng, YH; Lin, YT; Hsieh, HP; Chen, CT; Lien, TW; Lee, HJ; Mahindroo, N; Prakash, E; Yueh, A; Chen, HY; Goparaju, CMV; Chen, X; Liao, CC; Chao, YS; Hsu, JTA; Wu, SY
國家衛生研究院 2006-05 Antitubulin agents for the treatment of cancer - a medicinal chemistry update Mahindroo, N; Liou, JP; Chang, JY; Hsieh, HP
國家衛生研究院 2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies Mahindroo, N; Wang, CC; Liao, CC; Huang, CF; Lu, IL; Lien, TW; Peng, YH; Huang, WJ; Lin, YT; Hsu, MC; Lin, CH; Tsai, CH; Hsu, JTA; Chen, X; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-01-12 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV Tsu, H; Chen, X; Chen, CT; Lee, SJ; Chang, CN; Kao, KH; Coumar, MS; Yeh, YT; Chien, CH; Wang, HS; Lin, KT; Chang, YY; Wu, SH; Chen, YS; Lu, IL; Wu, SY; Tsai, TY; Chen, WC; Hsieh, HP; Chao, YS; Jiaang, WT
國家衛生研究院 2006-01-01 Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system Hwang, DR;Wu, YS;Chang, CW;Lien, TW;Chen, WC;Tan, UK;Hsu, JTA;Hsieh, HP
臺北醫學大學 2006 7-Aroyl-aminoindoline-1-sulfonamides as a Novel Class of Potent Antitubulin Agents 劉景平; 陳繼明; Chang JY; Hsieh HP; Chang CY; Hsu KS; Chiang YF; Chen CM; Kuo CC; Liou JP*
臺北醫學大學 2006 Antitubulin agents for the treatment of cancer-a medicinal chemistry update 劉景平; Mahindroo N; Liou JP; Chang JY; Hsieh HP
國家衛生研究院 2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities Mahindroo, N; Huang, CF; Peng, YH; Wang, CC; Liao, CC; Lien, TW; Chittimalla, SK; Huang, WJ; Chai, CH; Prakash, E; Chen, CP; Hsu, TA; Peng, CH; Lu, IL; Lee, LH; Chang, YW; Chen, WC; Chou, YC; Chen, CT; Goparaju, CMV; Chen, YS; Lan, SJ; Yu, MC; Chen, X; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2005-08-23 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2005-05 Shear stress inhibits smooth muscle cell-induced inflammatory gene expression in endothelial cells - Role of NF-kappa B Chiu, JJ; Chang, SF; Lee, PL; Lee, CI; Tsai, MC; Lee, DY; Hsieh, HP; Usami, S; Chien, S
國家衛生研究院 2005-05 Pharmaceutical design of antimitotic agents based on combretastatins Hsieh, HP;Liou, JP;Mahindroo, N
國家衛生研究院 2005-03 Promazine analogues as potential anti SARS-CoV drugs Hsieh, HP;Wu, YS;Lu, PH;Chen, CM;Chao, YC;Jan, JT;Huei-Ru, L;Ma, SH;Chao, YS;Hsu, TA

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