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教育部委託研究計畫      計畫執行:國立臺灣大學圖書館
 
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機構 日期 題名 作者
國家衛生研究院 2010-06-15 Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院 2010-06 Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis Chen, JC;Uang, BJ;Lyu, PC;Chang, JY;Liu, KJ;Kuo, CC;Hsieh, HP;Wang, HC;Cheng, CS;Chang, YH;Chang, MDT;Chang, WSW;Lin, CC
國家衛生研究院 2010-03-30 Pyrrolidine compounds Jiaang, WT;Chen, X;Wu, SY;Chao, YS;Hsieh, HP
國家衛生研究院 2010-03-11 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院 2010-02-25 Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives Yeh, JY;Coumar, MS;Horng, JT;Shiao, HY;Kuo, FM;Lee, HL;Chen, IC;Chang, CW;Tang, WF;Tseng, SN;Chen, CJ;Shih, SR;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院 2010-02-23 Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity Shih, SR;Chu, TY;Reddy, GR;Tseng, SN;Chen, HL;Tang, WF;Wu, MS;Yeh, JY;Chao, YS;Hsu, JTA;Hsieh, HP;Horng, JT
國家衛生研究院 2010-02-01 Identification, SAR studies, and X-ray Co-crystallographic analysis of a novel furanopyrimidine aurora kinase a inhibitor Coumar, MS;Tsai, MT;Chu, CY;Uang, BJ;Lin, WH;Chang, CY;Chang, TY;Leou, JS;Teng, CH;Wu, JS;Fang, MY;Chen, CH;Hsu, JTA;Wu, SY;Chao, YS;Hsieh, HP
國家衛生研究院 2010-02 Comparative molecular field analysis of anti-tubulin agents with indole ring binding at the colchicine binding site Lin, IH;Hsu, CC;Wang, SH;Hsieh, HP;Sun, YC
國家衛生研究院 2010-01 BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses Shih, SR;Horng, JT;Poon, LL;Chen, TC;Yeh, JY;Hsieh, HP;Tseng, SN;Chiang, C;Li, WL;Chao, YS;Hsu, JT
臺北醫學大學 2010 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors Nien, CY;Chen, YC;Kuo, CC;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Liou, JP;Chang, JY
國家衛生研究院 2009-12-15 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2009-12-01 芳香羰吲哚化合物 Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2009-09 Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development Hsieh, HP;Coumarrs, MS;Chu, CY;Ho, YL;Tsai, MT;Lin, WH;Chen, CH;Song, JS;Hsu, JTA;Chao, YS
國家衛生研究院 2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach Wu, YS;Coumar, MS;Chang, JY;Sun, HY;Kuo, FM;Kuo, CC;Chen, YJ;Chang, CY;Hsiao, CL;Liou, JP;Chen, CP;Yao, HT;Chiang, YK;Tan, UK;Chen, CT;Chu, CY;Wu, SY;Yeh, TK;Lin, CY;Hsieh, HP
中國醫藥大學 2009-08 Synthesis and Evaluation of 3-Aroylindoles as Anticancer Agents: Metabolite Approach. (Wu YS); (Coumar MS); (Chang JY); (Sun HY); (Kuo FM); (Kuo CC); (Chen YJ); (Chang CY); (Hsiao CL); (Liou JP); (Chen CP); 姚賢宗(Hsien-Tsung Yao); (Chiang YK); (Tan UK); (Chen CT); (Chu CY); (Wu SY); (Yeh TK); (Lin CY); (Hsieh HP)*
國家衛生研究院 2009-07-23 Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity Chiang, YK;Kuo, CC;Wu, YS;Chen, CT;Coumar, MS;Wu, JS;Hsieh, HP;Chang, CY;Jseng, HY;Wu, MH;Leou, JS;Song, JS;Chang, JY;Lyu, PC;Chao, YS;Wu, SY
國家衛生研究院 2009-07-03 Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers Cheung, CH;Chen, HH;Kuo, CC;Chang, CY;Coumar, MS;Hsieh, HP;Chang, JY
國家衛生研究院 2009-06-09 Treatment of coronavirus infection Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW
國家衛生研究院 2009-05-05 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2009-05 Down-regulation of survivin enhances sensitivity to BPROL075 in human cancer cells via caspase-independent mechanisms Cheung, CHA;Chang, CY;Hsieh, HP;Chang, JY
國家衛生研究院 2009-04-24 Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway Chen, KF;Yeh, PY;Hsu, C;Hsu, CH;Lu, YS;Hsieh, HP;Chen, PJ;Cheng, AL
國家衛生研究院 2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists Lin, CH;Peng, YH;Coumar, MS;Chittimalla, SK;Liao, CC;Lyn, PC;Huang, CC;Lien, TW;Lin, WH;Hsu, JT;Cheng, JH;Chen, X;Wu, JS;Chao, YS;Lee, HJ;Juo, CG;Wu, SY;Hsieh, HP
國家衛生研究院 2009-04-17 Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents Lai, MJ;Kuo, CC;Yeh, TK;Hsieh, HP;Chen, LT;Pan, WY;Hsu, KY;Chang, JY;Liou, JP
國家衛生研究院 2009-04 Aurora kinase inhibitors in preclinical and clinical testing Cheung, CH;Coumar, MS;Hsieh, HP;Chang, JY
國家衛生研究院 2009-03 Advances in Aurora kinase inhibitor patents Coumar, MS;Cheung, CHA;Chang, JY;Hsieh, HP
國家衛生研究院 2009-03 Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors Hsieh, HP;Coumar, MS;Lin, CW;Reddy, GR;Tsai, MT;Lin, WH;Hsu, TA;Wu, SY
國家衛生研究院 2009-02-26 Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity Coumar, MS;Leou, JS;Shukla, P;Wu, JS;Dixit, AK;Lin, WH;Chang, CY;Lien, TW;Tan, UK;Chen, CH;Hsu, JTA;Chao, YS;Wu, SY;Hsieh, HP
國家衛生研究院 2009-02 Aurintricarboxylic acid inhibits influenza virus neuraminidase Hung, HC;Tseng, CP;Yang, JM;Ju, YW;Tseng, SN;Chen, YF;Chao, YS;Hsieh, HP;Shih, SR;Hsu, JTA
國家衛生研究院 2009-01-22 Pyrrolidine compounds Chao, YS;Chen, X;Hsieh, HP;Jiaang, WT;Wu, SY
國家衛生研究院 2008-12-25 Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents Reddy, GR;Kuo, CC;Tan, UK;Coumar, MS;Chang, CY;Chiang, YK;Lai, MJ;Yeh, JY;Wu, SY;Chang, JY;Liou, JP;Hsieh, HP
國家衛生研究院 2008-12-11 吲哚化合物 Hsieh, HP;Mahindroo, N;Hsu, TA;Huang, CF;Chen, X;Chao, YS
國家衛生研究院 2008-11-25 Anti-tumor compounds Hsieh, HP;Chao, YS;Liou, JP;Chang, JY;Tung, YS
國家衛生研究院 2008-11-11 Indole compounds Hsieh, HP;Mahindroo, NH;Hsu, TA;Huang, CF;Chen, X;Chao, YS
國家衛生研究院 2008-09-16 Pyrrolidine compounds Jiaang, WT;Chao, YS;Hsieh, HP
國家衛生研究院 2008-07-24 Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors Liou, JP; Wu, ZY; Kuo, CC; Chang, CY; Lu, PY; Chen, CM; Hsieh, HP; Chang, JY
國家衛生研究院 2008-07-21 吡咯啉啶化合物 Jiaang, WT;Wu, SY;Chen, X;Chao, YS;Hsieh, HP
國家衛生研究院 2008-07-01 Pyrrolidine compounds Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院 2008-07 Anti-HSV activity of digitoxin and its possible mechanisms Su, CT; Hsu, JTA; Hsieh, HP; Lin, PH; Chen, TC; Kao, CL; Lee, CN; Chang, SY
國立臺灣大學 2008-07 Anti-HSV activity of digitoxin and its possible mechanisms Su, CT; Hsu, JT; Hsieh, HP; Lin, PH; Chen, TC; Kao, CL; Lee, CN; Chang, SY
國家衛生研究院 2008-06-01 A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors Lin, WH; Song, JS; Chang, TY; Chang, CY; Fu, YN; Yeh, CL; Wu, SH; Huang, YW; Fang, MY; Lien, TW; Hsieh, HP; Chao, YS; Huang, SF; Tsai, SF; Wang, LM; Hsu, JTA; Chen, YR
國家衛生研究院 2008-05-01 抗腫瘤化合物 Hsieh, HP;Liou, JP;Chang, JY;Tung, YS;Chao, YS
國家衛生研究院 2008-05 Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana Chou, YC; Prakash, E; Huang, CF; Lien, TW; Chen, X; Su, IJ; Chao, YS; Hsieh, HP; Hsu, JTA
國家衛生研究院 2008-04-15 Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus Chou, CY; Chien, CH; Han, YS; Prebanda, MT; Hsieh, HP; Turk, B; Chang, GG; Chen, X
國家衛生研究院 2008-03-13 Synthesis and biological evaluation of 1-methyl-2-(3 ',4 ',5 '-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors Romagnoli, R; Baraldi, PG; Sarkar, T; Carrion, MD; Cara, CL; Cruz-Lopez, O; Preti, D; Tabrizi, MA; Tolomeo, M; Grimaudo, S; Di Cristina, A; Zonta, N; Balzarini, J; Brancale, A; Hsieh, HP; Hamel, E
國家衛生研究院 2008-03-10 Reactions of 2-hydroxybenzophenones with Corey-Chaykovsky reagent Chittimalla, SK; Chang, TC; Liu, TC; Hsieh, HP; Liao, CC
國家衛生研究院 2008-03-01 Aurora kinase A inhibitors: Identification, SAR exploration and molecular modeling of 6,7-dihydro-4H-pyrazolo-[1,5-a]pyrrolo[3,4-d]pyrimidine-5,8-dione scaffold Coumar, MS; Wu, JS; Leou, JS; Tan, UK; Chang, CY; Chang, TY; Lin, WH; Hsu, JTA; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2008-02-11 一種抗病毒之醫藥組合物 Hsu, TA;Hsieh, HP;Juan, LJ;Chang, SY;Kuo, YH
國家衛生研究院 2008-02-07 First total syntheses of (+/-)-annuionone B and (+/-)-tanarifuranonol Shiao, HY; Hsieh, HP; Liao, CC
國家衛生研究院 2008-02 A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells Kao, YH; Hsieh, HP; Chitlimalla, SK; Pan, WY; Kuo, CC; Tsai, YC; Lin, WH; Chuang, SE; Chang, JY
臺北醫學大學 2008 Discovery of 4-Amino and 4-Hydroxy-1-Aroylindoles as Potent Tubulin Polymerization Inhibitors 劉景平; Liou JP; Wu ZY; Kuo CC; Chang CY; Lu PY; Chen CM; Hsieh HP; Chang JY

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