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教育部委託研究計畫      計畫執行:國立臺灣大學圖書館
 
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機構 日期 題名 作者
國家衛生研究院 2014-05 Facile identification of dual FLT3-Aurora A inhibitors: A computer-guided drug design approach ChangHsu, Y;Ke, YY;Shiao, HY;Lee, CC;Lin, WH;Chen, CH;Yen, KJ;Hsu, JTA;Chang, C;Hsieh, HP
國家衛生研究院 2014-05 Cover Picture: Facile identification of dual FLT3–aurora a inhibitors: A computer-guided drug design approach (ChemMedChem 5/2014) Chang Hsu, Y;Ke, YY;Shiao, HY;Lee, CC;Lin, WH;Chen, CH;Yen, KJ;Hsu, JTA;Chang, C;Hsieh, HP
國家衛生研究院 2014-04-29 Quinoline compounds and their use for treating viral infection Hsieh, HP;Hsu, TA;Yeh, JY;Chao, YS
國家衛生研究院 2014-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院 2014-03 DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study Shiao, HY;Hsu, TAJ;Chen, CT;Yeh, TK;Hsieh, HP
國家衛生研究院 2014-03 Efficient virtual screening using ligand efficiency based approach Hsieh, HP;Ke, YY;Coumar, MS;Lin, WH;Wang, WC;Shiao, HY;Hsu, TAJ
臺北醫學大學 2014 CDKN1A-mediated Responsiveness of MLL-AF4-positive Acute Lymphoblastic Leukemia to Aurora Kinase-A Inhibitors Chen, YP;Lin, HJ;Chen, JS;Tsai, MY;Hsieh, HP;Chang, JY;Chen, NF;Chang, KC;Huang, WT;Su, WC;Yang, ST;Chang, WC;Hung, LY;Chen, TY
國家衛生研究院 2013-11-21 治療癌症的醫藥組成物 Hsieh, HP;Chang, JY;Kuo, CC;Chao, YS
國家衛生研究院 2013-11 A development drug candidate targeting EGFR kinase for lung cancer: DBPR112 Hsieh, HP;Shiao, HY;Chen, CT;Yeh, TK
國家衛生研究院 2013-11 Peptide-mediated liposomal doxorubicin enhances drug delivery efficiency and therapeutic efficacy in lung cancer animal models Wu, HC;Chang, DK;Li, PC;Hsieh, HP
國家衛生研究院 2013-10-01 喹啉化合物及包含其之治療病毒感染之醫藥組成物 Hsieh, HP;Hsu, TA;Yeh, JY;Chao, YS
國家衛生研究院 2013-09-22 A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment [Erratum:International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411] Shionome, Y;Lin, WH;Shiao, HY;Hsieh, HP;Hsu, JTA;Ouchi, T
國家衛生研究院 2013-08-21 Fused multicyclic compounds as protein kinase inhibitors Hsieh, HP;Coumar, SM;Chao, YS
國家衛生研究院 2013-08-13 Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors Hsieh, HP;Coumar, SM;Hsu, TA;Lin, WH;Chen, YR;Chao, YS
國家衛生研究院 2013-07-25 Pronounced induction of endoplasmic reticulum stress and tumor suppression by surfactant-free poly(lactic-co-glycolic acid) nanoparticles via modulation of the PI3K signaling pathway Hou, CC;Tsai, TL;Su, WP;Hsieh, HP;Yeh, CS;Shieh, DB;Su, WC
國家衛生研究院 2013-07-01 做為蛋白質激酶抑制劑之稠合多環化合物 Hsieh, HP;Coumar, MS;Chao, YS
國家衛生研究院 2013-06-28 Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor Shiao, HY;Coumar, MS;Chang, CW;Ke, YY;Chi, YH;Chu, CY;Sun, HY;Chen, CH;Lin, WH;Fung, KS;Kuo, PC;Huang, CT;Chang, KY;Lu, CT;Hsu, JT;Chen, CT;Jiaang, WT;Chao, YS;Hsieh, HP
國家衛生研究院 2013-06 An antimitotic and antivascular agent BPR0L075 overcomes multidrug resistance and induces mitotic catastrophe in paclitaxel-resistant ovarian cancer cells Wang, X;Wu, E;Wu, J;Wang, TL;Hsieh, HP;Liu, X
國家衛生研究院 2013-05 Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules Wu, JM;Chen, CT;Coumar, MS;Lin, WH;Chen, ZJ;Hsu, JT;Peng, YH;Shiao, HY;Chu, CY;Wu, JS;Lin, CT;Chen, CP;Hsueh, CC;Chang, KY;Kao, LP;Huang, CY;Chao, YS;Wu, SY;Hsieh, HP;Chi, YH
國家衛生研究院 2013-05 Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors Peng, YH;Shiao, HY;Tu, CH;Liu, PM;Hsu, JT;Amancha, PK;Wu, JS;Coumar, MS;Chen, CH;Wang, SY;Lin, WH;Sun, HY;Chao, YS;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院 2013-04-29 A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment Shionome, Y;Lin, WH;Shiao, HY;Hsieh, HP;Hsu, JTA;Ouchi, T
國家衛生研究院 2013-04-07 BPR000K, a novel Aurora kinase inhibitor Chao, YS;Hsu, JTA;Chen, CT;Yeh, TK;Pan, SL;Hsieh, HP
國家衛生研究院 2013-04-07 Kinase-focused library: Design and synthesis of pyrimidines derivatives bearing amino substituents using high throughput parallel synthesis Wang, WC;Hsieh, HP
國家衛生研究院 2013-04-07 3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor Ke, YY;Shiao, HY;Hsu, YC;Chang-Chu, Y;Wang, WC;Lee, YC;Lin, WH;Hsu, JTA;Chang, CW;Lin, CW;Yeh, TK;Chao, YS;Coumar, MS;Hsieh, HP
國家衛生研究院 2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 Sun, HY;Hsu, JTA;Chen, CT;Yeh, TK;Pan, SL;Chao, YS;Hsieh, HP
國家衛生研究院 2013-04 Design and synthesis of Aurora kinase inhibitors as anticancer agents Hsu, YC;Shiao, HY;Lin, WH;Hsu, JTA;Chen, CT;Chao, YS;Hsieh, HP
國家衛生研究院 2013-02-20 Parallel screening of Wild-Type and drug-resistant targets for anti-resistance neuraminidase inhibitors Hsu, KC;Hung, HC;Horng, JT;Fang, MY;Chang, CY;Li, LT;Chen, IJ;Chen, YC;Chou, DL;Chang, CW;Hsieh, HP;Yang, JM;Hsu, JT
國家衛生研究院 2013-02-11 作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物 Hsieh, HP;Coumar, MS;Chao, YS;Hsu, TA;Lin, WH;Chen, YR
國家衛生研究院 2013-01 3D-QSAR-assisted drug design: Identification of a potent quinazoline-based aurora kinase inhibitor Ke, YY;Shiao, HY;Hsu, YC;Chu, CY;Wang, WC;Lee, YC;Lin, WH;Chen, CH;Hsu, JTA;Chang, CW;Lin, CW;Yeh, TK;Chao, YS;Coumar, MS;Hsieh, HP
國家衛生研究院 2013-01 Substituent effects on the photorearrangements of unsymmetrically substituted diazinobarrelenes Hsieh, HP;Chen, AC;Villarante, NR;Chuang, GJ;Liao, CC
國家衛生研究院 2012-12 An efficient, mild and scalable synthesis of bioactive compounds containing the angelicin scaffold Shiao, HY;Kuo, CC;Horng, JT;Shih, SR;Chang, SY;Liao, CC;Hsu, JTA;Kumar, AP;Chao, YS;Hsieh, HP
國家衛生研究院 2012-09 Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization Yeh, JY;Coumar, MS;Shiao, HY;Lin, TJ;Lee, YC;Hung, HC;Ko, S;Kuo, FM;Fang, MY;Huang, YL;Hsu, JT;Yeh, TK;Shih, SR;Chao, YS;Horng, JT;Hsieh, HP
國家衛生研究院 2012-08-24 Tubulin-destabilizing agent BPR0L075 induces vascular-disruption in human breast cancer mammary fat pad xenografts Liu, L;Beck, H;Wang, X;Hsieh, HP;Mason, RP;Liu, X
國家衛生研究院 2012-05-11 作為極光激酶抑制劑之稠合雙環嘧啶化合物 Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院 2012-04-21 吡咯啉啶化合物 Jiaang, WT;Chao, YS;Hsieh, HP
國家衛生研究院 2012-03-25 Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors Hsieh, HP;Shiao, HY;Lin, WH;Hsu, JTA;Chao, YS
國家衛生研究院 2012-03-20 Fused bicyclic pyrimidine compounds as aurora kinase inhibitors Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院 2012-03-06 Indole compounds Hsieh, HP;Liou, JP;Chang, JY;Chang, CW
國家衛生研究院 2012-02 Identification of BPR3P0128 as an Inhibitor of cap-snatching activities of influenza virus Hsu, JT;Yeh, JY;Lin, TJ;Li, ML;Wu, MS;Hsieh, CF;Chou, YC;Tang, WF;Lau, KS;Hung, HC;Fang, MY;Ko, S;Hsieh, HP;Horng, JT
國家衛生研究院 2012-01-17 Pyrrolidine compounds Jiaang, WT;Chen, X;Wu, SY;Hsieh, HP;Chao, YS
國家衛生研究院 2012-01 A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors Lin, WH;Song, JS;Lien, TW;Chang, CY;Wu, SH;Huang, YW;Chang, TY;Fang, MY;Yen, KJ;Chen, CH;Chu, CY;Hsieh, HP;Chen, YR;Chao, YS;Hsu, JT
國家衛生研究院 2011-11-15 Coumarin compounds and their use for treating cancer Hsieh, HP;Chang, JY;Kuo, CC;Chao, YS
國家衛生研究院 2011-09-23 BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo Hsieh, HP;Cheung, CHA;Lin, WH;Hsu, TA;Coumar, MS;Chao, YS;Chang, JY
國家衛生研究院 2011-09 Synthesis and biological evaluation of 1-(4′-Indolyl and 6′-Quinolinyl) indoles as a new class of potent anticancer agents Lai, MJ;Chang, JY;Lee, HY;Kuo, CC;Lin, MH;Hsieh, HP;Chang, CY;Wu, JS;Wu, SY;Shey, KS;Liou, JP
國家衛生研究院 2011-09 Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway Lin, PH;Ke, YY;Su, CT;Shiao, HY;Hsieh, HP;Chao, YK;Lee, CN;Kao, CL;Chao, YS;Chang, SY
國家衛生研究院 2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells Cheung, CH;Lin, WH;Hsu, TA;Hour, TC;Yeh, TK;Ko, S;Lien, TW;Coumar, MS;Liu, JF;Lai, WY;Shiao, HY;Lee, TR;Hsieh, HP;Chang, JY
國家衛生研究院 2011-07-11 抑制C型肝炎病毒感染之倍半帖內酯類化合物及其醫藥組成物 Hsieh, HP;Hsu, TA;Hwang, DR
國家衛生研究院 2011-06-21 抑制冠狀病毒之醫藥組合物 Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW
國家衛生研究院 2011-06-21 抑制冠狀病毒之醫藥組合物 Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW
國家衛生研究院 2011-06-21 抑制冠狀病毒之醫藥組合物 Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW

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