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Showing items 66-115 of 265 (6 Page(s) Totally)
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| 國家衛生研究院 |
2016-11-23 |
Fused bicyclic pyrimidine compounds as aurora kinase inhibitors
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Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS |
| 國家衛生研究院 |
2016-07 |
Therapeutic polymeric nanoparticles and the methods of making and using thereof: A patent evaluation of WO2015036792
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Sarvagalla, S;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2016-06-07 |
Fused bicyclic pyrimidine compounds as aurora kinase inhibitors
|
Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS |
| 國家衛生研究院 |
2016-03 |
Disruption of protein-protein interactions: Hot spot detection, structure-based virtual screening and in vitro testing for the anti-cancer drug target survivin
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Sarvagalla, S;Cheung, CHA;Tsai, JY;Hsieh, HP;Coumar, MS |
| 國家衛生研究院 |
2015-08-20 |
Fused bicyclic pyrimidine compounds as Aurora kinase inhibitors
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Coumar, MS;Chao, YS;Hsu, TA;Wu, SY;Hsieh, HP |
| 國家衛生研究院 |
2015-08 |
BPR2P001S0, a Coumarin derivative, induced cell cycle arrest in A549 through inhibiting PDPK1 activity
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Lin, PH;Jao, TM;Hung, YL;Hsieh, HP;Yang, YC;Chang, SY |
| 國家衛生研究院 |
2015-08 |
Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia
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Hsieh, HP;Hsu, YC;Ke, YY;Shiao, HY;Chang, CW;Lin, WH;Hsu, TA;Yeh, TK;Chen, CT |
| 國家衛生研究院 |
2015-08 |
Optimization of furanopyrimidine-based kinase inhibitors: Identification of a BTK kinase inhibitor for the treatment of B cell lymphoma
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Wang, WC;Hsu, YC;Shiao, HY;Hung, HC;Kuo, CC;Lee, JC;Hsu, TA;Hsieh, HP |
| 國家衛生研究院 |
2015-08 |
Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors
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Shiao, HY;Wang, WC;Hsu, YC;Ke, YY;Hsu, TA;Hsieh, HP |
| 國家衛生研究院 |
2015-07-31 |
作為極光激酶抑制劑的稠合雙環嘧啶化合物
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Hsieh, HP;Coumar, MS;Wu, SY;Hsu, TA;Chao, YS |
| 國家衛生研究院 |
2015-07-22 |
作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物
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Hsieh, HP;Coumar, MS;Hsu, TA;Lin, WH;Chen, YR;Chao, YS |
| 國家衛生研究院 |
2015-06-29 |
Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification
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Ke, YY;Singh, VK;Coumar, MS;Hsu, YC;Wang, WC;Song, JS;Chen, CH;Lin, WH;Wu, SH;Hsu, JT;Shih, C;Hsieh, HP |
| 國家衛生研究院 |
2015-04-14 |
Fused multicyclic compounds as protein kinase inhibitors
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Hsieh, HP;Coumar, MS;Chao, YS |
| 國家衛生研究院 |
2015-02 |
Function-oriented development of CXCR4 antagonists as selective human immunodeficiency virus (HIV)-1 entry inhibitors
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Wu, CH;Wang, CJ;Chang, CP;Cheng, YC;Song, JS;Jan, JJ;Chou, MC;Ke, YY;Ma, J;Wong, YC;Hsieh, TC;Tien, YC;Gullen, EA;Lo, CF;Cheng, CY;Liu, YW;Sadani, AA;Tsai, CH;Hsieh, HP;Tsou, LK;Shia, KS |
| 國家衛生研究院 |
2015-01 |
Identification of ligand efficient, fragment-like hits from an HTS library: Structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity
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Sarvagalla, S;Singh, VK;Ke, YY;Shiao, HY;Lin, WH;Hsieh, HP;Hsu, JTA;Coumar, MS |
| 國家衛生研究院 |
2014-12 |
BPR-3P0128 inhibits RNA-dependent RNA polymerase elongation and VPg uridylylation activities of Enterovirus 71
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Balaji, VA;Chen, GW;Hsieh, PT;Horng, JT;Hsu, JTA;Hsieh, HP;Chen, TC;Weng, KF;Shih, SR |
| 國家衛生研究院 |
2014-11 |
Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent
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Hsieh, HP;Kuo, CC;Chiu, JJ;Hsu, TA;Yeh, TK;Chen, CT |
| 國家衛生研究院 |
2014-10-29 |
作為極光激酶抑制劑的稠合雙環嘧啶化合物
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Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS |
| 國家衛生研究院 |
2014-10-21 |
化合物於製造治療病毒感染的藥物之用途
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Hsieh, HP;Hsu, TA;Yeh, JY;Horng, JT;Shih, SR;Chang, SY;Chao, YS |
| 國家衛生研究院 |
2014-10 |
Small-molecule EGFR tyrosine kinase inhibitors for the treatment of cancer
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Lee, CC;Shiao, HY;Wang, WC;Hsieh, HP |
| 國家衛生研究院 |
2014-10 |
Optimization of 5,6-fused pyrimidine-based kinase inhibitors by computer-aided drug design for the treatment of AML
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Hsu, YC;Shiao, HY;Ke, YY;Hsu, JTA;Lin, WH;Chen, CH;Hsieh, HP |
| 國家衛生研究院 |
2014-10 |
Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma
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Shiao, HY;Hsu, TA;Lin, WH;Yang, TT;Hsieh, HF;Chen, CT;Yeh, TK;Hsieh, HP |
| 國家衛生研究院 |
2014-08 |
CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors
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Chen, YP;Lin, HJ;Chen, JS;Tsai, MY;Hsieh, HP;Chang, JY;Chen, NF;Chang, KC;Huang, WT;Su, WC;Yang, ST;Chang, WC;Hung, LY;Chen, TY |
| 國家衛生研究院 |
2014-08 |
Ligand efficiency based approach for efficient virtual screening of compound libraries
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Ke, YY;Coumar, MS;Shiao, HY;Wang, WC;Chen, CW;Song, JS;Chen, CH;Lin, WH;Wu, SH;Hsu, JT;Chang, CM;Hsieh, HP |
| 國家衛生研究院 |
2014-07 |
Anaplastic lymphoma kinase (ALK) inhibitors: A review of design and discovery
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Wang, WC;Shiao, HY;Lee, CC;Fung, KS;Hsieh, HP |
| 國家衛生研究院 |
2014-05 |
Facile identification of dual FLT3-Aurora A inhibitors: A computer-guided drug design approach
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ChangHsu, Y;Ke, YY;Shiao, HY;Lee, CC;Lin, WH;Chen, CH;Yen, KJ;Hsu, JTA;Chang, C;Hsieh, HP |
| 國家衛生研究院 |
2014-05 |
Cover Picture: Facile identification of dual FLT3–aurora a inhibitors: A computer-guided drug design approach (ChemMedChem 5/2014)
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Chang Hsu, Y;Ke, YY;Shiao, HY;Lee, CC;Lin, WH;Chen, CH;Yen, KJ;Hsu, JTA;Chang, C;Hsieh, HP |
| 國家衛生研究院 |
2014-04-29 |
Quinoline compounds and their use for treating viral infection
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Hsieh, HP;Hsu, TA;Yeh, JY;Chao, YS |
| 國家衛生研究院 |
2014-03-20 |
Fused bicyclic pyrimidine compounds as aurora kinase inhibitors
|
Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS |
| 國家衛生研究院 |
2014-03 |
DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study
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Shiao, HY;Hsu, TAJ;Chen, CT;Yeh, TK;Hsieh, HP |
| 國家衛生研究院 |
2014-03 |
Efficient virtual screening using ligand efficiency based approach
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Hsieh, HP;Ke, YY;Coumar, MS;Lin, WH;Wang, WC;Shiao, HY;Hsu, TAJ |
| 臺北醫學大學 |
2014 |
CDKN1A-mediated Responsiveness of MLL-AF4-positive Acute Lymphoblastic Leukemia to Aurora Kinase-A Inhibitors
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Chen, YP;Lin, HJ;Chen, JS;Tsai, MY;Hsieh, HP;Chang, JY;Chen, NF;Chang, KC;Huang, WT;Su, WC;Yang, ST;Chang, WC;Hung, LY;Chen, TY |
| 國家衛生研究院 |
2013-11-21 |
治療癌症的醫藥組成物
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Hsieh, HP;Chang, JY;Kuo, CC;Chao, YS |
| 國家衛生研究院 |
2013-11 |
A development drug candidate targeting EGFR kinase for lung cancer: DBPR112
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Hsieh, HP;Shiao, HY;Chen, CT;Yeh, TK |
| 國家衛生研究院 |
2013-11 |
Peptide-mediated liposomal doxorubicin enhances drug delivery efficiency and therapeutic efficacy in lung cancer animal models
|
Wu, HC;Chang, DK;Li, PC;Hsieh, HP |
| 國家衛生研究院 |
2013-10-01 |
喹啉化合物及包含其之治療病毒感染之醫藥組成物
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Hsieh, HP;Hsu, TA;Yeh, JY;Chao, YS |
| 國家衛生研究院 |
2013-09-22 |
A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment [Erratum:International Journal of Biological Sciences. 2013 Apr 29;9(4):403-411]
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Shionome, Y;Lin, WH;Shiao, HY;Hsieh, HP;Hsu, JTA;Ouchi, T |
| 國家衛生研究院 |
2013-08-21 |
Fused multicyclic compounds as protein kinase inhibitors
|
Hsieh, HP;Coumar, SM;Chao, YS |
| 國家衛生研究院 |
2013-08-13 |
Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors
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Hsieh, HP;Coumar, SM;Hsu, TA;Lin, WH;Chen, YR;Chao, YS |
| 國家衛生研究院 |
2013-07-25 |
Pronounced induction of endoplasmic reticulum stress and tumor suppression by surfactant-free poly(lactic-co-glycolic acid) nanoparticles via modulation of the PI3K signaling pathway
|
Hou, CC;Tsai, TL;Su, WP;Hsieh, HP;Yeh, CS;Shieh, DB;Su, WC |
| 國家衛生研究院 |
2013-07-01 |
做為蛋白質激酶抑制劑之稠合多環化合物
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Hsieh, HP;Coumar, MS;Chao, YS |
| 國家衛生研究院 |
2013-06-28 |
Optimization of ligand and lipophilic efficiency to identify an in vivo active furano-pyrimidine aurora kinase inhibitor
|
Shiao, HY;Coumar, MS;Chang, CW;Ke, YY;Chi, YH;Chu, CY;Sun, HY;Chen, CH;Lin, WH;Fung, KS;Kuo, PC;Huang, CT;Chang, KY;Lu, CT;Hsu, JT;Chen, CT;Jiaang, WT;Chao, YS;Hsieh, HP |
| 國家衛生研究院 |
2013-06 |
An antimitotic and antivascular agent BPR0L075 overcomes multidrug resistance and induces mitotic catastrophe in paclitaxel-resistant ovarian cancer cells
|
Wang, X;Wu, E;Wu, J;Wang, TL;Hsieh, HP;Liu, X |
| 國家衛生研究院 |
2013-05 |
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
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Wu, JM;Chen, CT;Coumar, MS;Lin, WH;Chen, ZJ;Hsu, JT;Peng, YH;Shiao, HY;Chu, CY;Wu, JS;Lin, CT;Chen, CP;Hsueh, CC;Chang, KY;Kao, LP;Huang, CY;Chao, YS;Wu, SY;Hsieh, HP;Chi, YH |
| 國家衛生研究院 |
2013-05 |
Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors
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Peng, YH;Shiao, HY;Tu, CH;Liu, PM;Hsu, JT;Amancha, PK;Wu, JS;Coumar, MS;Chen, CH;Wang, SY;Lin, WH;Sun, HY;Chao, YS;Lyu, PC;Hsieh, HP;Wu, SY |
| 國家衛生研究院 |
2013-04-29 |
A novel Aurora-A inhibitor, BPR1K0609S1, sensitizes colorectal tumor cells to 5-fluorofracil (5-FU) treatment
|
Shionome, Y;Lin, WH;Shiao, HY;Hsieh, HP;Hsu, JTA;Ouchi, T |
| 國家衛生研究院 |
2013-04-07 |
BPR000K, a novel Aurora kinase inhibitor
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Chao, YS;Hsu, JTA;Chen, CT;Yeh, TK;Pan, SL;Hsieh, HP |
| 國家衛生研究院 |
2013-04-07 |
Kinase-focused library: Design and synthesis of pyrimidines derivatives bearing amino substituents using high throughput parallel synthesis
|
Wang, WC;Hsieh, HP |
| 國家衛生研究院 |
2013-04-07 |
3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor
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Ke, YY;Shiao, HY;Hsu, YC;Chang-Chu, Y;Wang, WC;Lee, YC;Lin, WH;Hsu, JTA;Chang, CW;Lin, CW;Yeh, TK;Chao, YS;Coumar, MS;Hsieh, HP |
| 國家衛生研究院 |
2013-04-07 |
Development drug candidate targeting EGFR kinase: DBPR112
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Sun, HY;Hsu, JTA;Chen, CT;Yeh, TK;Pan, SL;Chao, YS;Hsieh, HP |
Showing items 66-115 of 265 (6 Page(s) Totally)
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