| 臺大學術典藏 |
2022-04-15T03:14:22Z |
Instability of succinate dehydrogenase in SDHD polymorphism connects reactive oxygen species production to nuclear and mitochondrial genomic mutations in yeast
|
Hsieh M.-H.; Tsai C.-H.; Lin C.-C.; Li T.-K.; Hung T.-W.; Chang L.-T.; Hsin L.-W.; SHU-CHUN TENG |
| 臺大學術典藏 |
2022-03-14T12:48:25Z |
Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates
|
Hsin L.-W.; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; Guh J.-H.; Chan Y.-L.; His C.-P.; Yang M.-S.; TSAI-KUN LI; Lee C.-H. |
| 臺大學術典藏 |
2022-03-14T12:48:24Z |
WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers
|
Hsiao C.-J.; TSAI-KUN LI; Chan Y.-L.; Hsin L.-W.; Liao C.-H.; Lee C.-H.; Lyu P.-C.; Guh J.-H. |
| 臺大學術典藏 |
2022-03-14T12:48:21Z |
Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles
|
Lee C.-H.; Hsieh M.-Y.; Hsin L.-W.; Chen H.-C.; Lo S.-C.; Fan J.-R.; Chen W.-R.; Chen H.-W.; Chan N.-L.; TSAI-KUN LI |
| 臺大學術典藏 |
2022-03-14T12:48:18Z |
Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers
|
Hsieh M.-H.; Tsai C.-H.; Lin C.-C.; TSAI-KUN LI; Hung T.-W.; Chang L.-T.; Hsin L.-W.; Teng S.-C. |
| 臺大學術典藏 |
2021-09-22T03:00:02Z |
Quinazolin-4-one derivatives as selective histone deacetylase-6 inhibitors for the treatment of Alzheimer's disease
|
CHAO-WU YU; Chang P.-T.; Hsin L.-W.; Chern J.-W. |
| 臺大學術典藏 |
2021-09-22T03:00:00Z |
High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma
|
Liu J.-R.; CHAO-WU YU; Hung P.-Y.; Hsin L.-W.; Chern J.-W. |
| 臺大學術典藏 |
2021-09-22T02:59:59Z |
Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity
|
Peng C.; Li Y.-H.; CHAO-WU YU; Cheng Z.-H.; Liu J.-R.; Hsu J.-L.; Hsin L.-W.; Huang C.-T.; Juan H.-F.; Chern J.-W.; Cheng Y.-S. |
| 臺大學術典藏 |
2021-07-26T09:45:04Z |
Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity
|
Peng C;Li Y.-H;Yu C.-W;Cheng Z.-H;Liu J.-R;Hsu J.-L;Hsin L.-W;Huang C.-T;Juan H.-F;Chern J.-W;Cheng Y.-S.; Peng C; JE-RUEI LIU et al. |
| 臺大學術典藏 |
2021-07-16T06:18:15Z |
Improved enamine-type addition of dehydroaporphine using microwave irradiation
|
Huang W.-J.; Huang C.-C.; Hsin L.-W.; Tsai Y.-M.; Lin C.-T.; Lin J.-H.; SHOEI-SHENG LEE |
| 臺大學術典藏 |
2021-06-02T05:43:57Z |
WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers
|
Hsiao C.-J.; Li T.-K.; Chan Y.-L.; Hsin L.-W.; Liao C.-H.; Lee C.-H.; Lyu P.-C.; JIH-HWA GUH |
| 臺大學術典藏 |
2021-06-02T05:43:57Z |
Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates
|
Hsin L.-W.; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; JIH-HWA GUH; Chan Y.-L.; His C.-P.; Yang M.-S.; Li T.-K.; Lee C.-H. |
| 臺大學術典藏 |
2021-05-31T06:17:56Z |
Activation of serotonin 5-HT7 receptor induces coronary flow increase in isolated rat heart
|
Chang Chien C.-C.; Hsin L.-W.; MING-JAI SU |
| 臺大學術典藏 |
2021-05-31T06:17:53Z |
A novel isoquinoline derivative exhibits anti-inflammatory properties and improves the outcomes of endotoxemia
|
Lee S.-Y.;Hsin L.-W.;Ming-Jai Su;Changchien C.-C.;Ku H.-C.; Lee S.-Y.; Hsin L.-W.; MING-JAI SU; ChangChien C.-C.; Ku H.-C. |
| 臺大學術典藏 |
2021-05-28T02:07:26Z |
Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity
|
Peng, C., Li, Y,.-H. Yu, C.-W., Cheng, J.-H., Liu, J.-R., Hsu, J.-L., Hsin, L.-W., Huang, C.-T.,?Juan, H.-F., Chern, J.-W., Cheng, Y.-S.; Peng, C.; Li, Y.-H.; Yu, C.-W.; Cheng, J.-H.; Liu, J.-R.; Hsu, J.-L.; Hsin, L.-W.; Huang, C.-T.; Juan, H.-F.; Chern, J.-W.; Cheng, Y.-S. |
| 臺大學術典藏 |
2021-05-24T06:35:21Z |
High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma
|
Liu, J.-R.;Yu, C.-W.;Hung, P.-Y.;Hsin, L.-W.;Chern, J.-W.; Liu, J.-R.; Yu, C.-W.; Hung, P.-Y.; Hsin, L.-W.; Chern, J.-W.; JE-RUEI LIU |
| 臺大學術典藏 |
2021-05-21T01:54:02Z |
Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity
|
Peng C.; Li, Y.H.; Yu, C.W.; Cheng, Z.H.; Liu, J.R.; Hsu, J.L.; Hsin, L.W.; Huang, C.T.; Juan, H.F.; Chern, J.W.; Cheng, Y.S. |
| 臺大學術典藏 |
2021-04-27T02:49:21Z |
Synthesis and analysis of 4-(3-fluoropropyl)-glutamic acid stereoisomers to determine the stereochemical purity of (4S)-4-(3-[18F]fluoropropyl)-L-glutamic acid ([18F]FSPG) for clinical use
|
Shih K.-T.; Huang Y.-Y.; Yang C.-Y.; Cheng M.-F.; YU-WEN TIEN; Shiue C.-Y.; Yen R.-F.; Hsin L.-W. |
| 臺大學術典藏 |
2021-03-18T05:58:58Z |
A Novel potential positron emission tomography imaging agent for vesicular monoamine transporter type 2
|
Huang Z.-R.; Tsai C.-L.; Huang Y.-Y.; Shiue C.-Y.; KAI-YUAN TZEN; Yen R.-F.; Hsin L.-W. |
| 臺大學術典藏 |
2021-03-18T05:58:54Z |
Synthesis and evaluation of 2-(2′-((dimethylamino)methyl)-4′-(2-fluoroethoxy-substituted)phenylthio)benzenamine derivatives as potential positron emission tomography imaging agents for serotonin transporters
|
Huang Y.-Y.; Chang L.-T.; Shen H.-Y.; Chen Y.-H.; KAI-YUAN TZEN; Shiue C.-Y.; Hsin L.-W. |
| 臺大學術典藏 |
2021-03-18T05:58:54Z |
An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans
|
Huang Y.-Y.; Chiu M.-J.; Yen R.-F.; Tsai C.-L.; Hsieh H.-Y.; Chiu C.-H.; Wu C.-H.; Hsin L.-W.; KAI-YUAN TZEN; Cheng C.-Y.; Ma K.-H.; Shiue C.-Y. |
| 臺大學術典藏 |
2020-11-03T11:56:55Z |
An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans
|
Huang Y.-Y.; Ming-Jang Chiu; Yen R.-F.; Tsai C.-L.; Hsieh H.-Y.; Chiu C.-H.; Wu C.-H.; Hsin L.-W.; Tzen K.-Y.; Cheng C.-Y.; Ma K.-H.; Shiue C.-Y.; Huang Y.-Y.; MING-JANG CHIU et al. |
| 臺大學術典藏 |
2020-09-23T07:36:08Z |
Prospective comparison of (4S)-4-(3- 18 F-fluoropropyl)-l-glutamate versus 18 F-fluorodeoxyglucose PET/CT for detecting metastases from pancreatic ductal adenocarcinoma: a proof-of-concept study
|
Mei-Fang Cheng;Huang Y.-Y.;Ho B.-Y.;Kuo T.-C.;Hsin L.-W.;Shiue C.-Y.;Kuo H.-C.;Jeng Y.-M.;Yen R.-F.;Tien Y.-W.; MEI-FANG CHENG; Huang Y.-Y.; Ho B.-Y.; Kuo T.-C.; Hsin L.-W.; Shiue C.-Y.; Kuo H.-C.; Jeng Y.-M.; Yen R.-F.; Tien Y.-W. |
| 臺大學術典藏 |
2020-09-23T06:22:21Z |
A Novel potential positron emission tomography imaging agent for vesicular monoamine transporter type 2
|
Hsin L.-W.; RUOH-FANG YEN; Tzen K.-Y.; Shiue C.-Y.; Huang Y.-Y.; Huang Z.-R.; Tsai C.-L. |
| 臺大學術典藏 |
2020-09-23T06:22:14Z |
Prospective comparison of (4S)-4-(3- 18 F-fluoropropyl)-l-glutamate versus 18 F-fluorodeoxyglucose PET/CT for detecting metastases from pancreatic ductal adenocarcinoma: a proof-of-concept study
|
Cheng M.-F.;Huang Y.-Y.;Ho B.-Y.;Kuo T.-C.;Hsin L.-W.;Shiue C.-Y.;Kuo H.-C.;Jeng Y.-M.;Ruoh-Fang Yen;Tien Y.-W.; Cheng M.-F.; Huang Y.-Y.; Ho B.-Y.; Kuo T.-C.; Hsin L.-W.; Shiue C.-Y.; Kuo H.-C.; Jeng Y.-M.; RUOH-FANG YEN; Tien Y.-W. |
| 臺大學術典藏 |
2020-09-23T06:22:13Z |
An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans
|
Huang Y.-Y.;Chiu M.-J.;Ruoh-Fang Yen;Tsai C.-L.;Hsieh H.-Y.;Chiu C.-H.;Wu C.-H.;Hsin L.-W.;Tzen K.-Y.;Cheng C.-Y.;Ma K.-H.;Shiue C.-Y.; Huang Y.-Y.; Chiu M.-J.; RUOH-FANG YEN; Tsai C.-L.; Hsieh H.-Y.; Chiu C.-H.; Wu C.-H.; Hsin L.-W.; Tzen K.-Y.; Cheng C.-Y.; Ma K.-H.; Shiue C.-Y. |
| 臺大學術典藏 |
2020-03-06T08:24:49Z |
Prospective comparison of (4S)-4-(3- 18 F-fluoropropyl)-l-glutamate versus 18 F-fluorodeoxyglucose PET/CT for detecting metastases from pancreatic ductal adenocarcinoma: a proof-of-concept study
|
Cheng M.-F.;Huang Y.-Y.;Ho B.-Y.;Kuo T.-C.;Hsin L.-W.;Shiue C.-Y.;Kuo H.-C.;Yung-Ming Jeng;Yen R.-F.;Tien Y.-W.; Cheng M.-F.; Huang Y.-Y.; Ho B.-Y.; Kuo T.-C.; Hsin L.-W.; Shiue C.-Y.; Kuo H.-C.; YUNG-MING JENG; Yen R.-F.; Tien Y.-W. |
| 臺大學術典藏 |
2020-03-04T05:34:50Z |
An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans
|
Huang Y.-Y.; MING-JANG CHIU; Yen R.-F.; Tsai C.-L.; Hsieh H.-Y.; Chiu C.-H.; Wu C.-H.; Hsin L.-W.; Tzen K.-Y.; Cheng C.-Y.; Ma K.-H.; Shiue C.-Y. |
| 臺大學術典藏 |
2020-02-20T06:53:03Z |
Prospective comparison of (4S)-4-(3- 18 F-fluoropropyl)-l-glutamate versus 18 F-fluorodeoxyglucose PET/CT for detecting metastases from pancreatic ductal adenocarcinoma: a proof-of-concept study
|
Kuo T.-C.; Hsin L.-W.; Shiue C.-Y.; Kuo H.-C.; Jeng Y.-M.; Yen R.-F.; YU-WEN TIEN; Cheng M.-F.;Huang Y.-Y.;Ho B.-Y.;Kuo T.-C.;Hsin L.-W.;Shiue C.-Y.;Kuo H.-C.;Jeng Y.-M.;Yen R.-F.;Yu-Wen Tien; Cheng M.-F.; Ho B.-Y.; Huang Y.-Y. |
| 臺大學術典藏 |
2019 |
Prospective comparison of (4S)-4-(3- 18 F-fluoropropyl)-l-glutamate versus 18 F-fluorodeoxyglucose PET/CT for detecting metastases from pancreatic ductal adenocarcinoma: a proof-of-concept study
|
Tien Y.-W.; Cheng M.-F.; Huang Y.-Y.; Ho B.-Y.; TING-CHUN KUO; Hsin L.-W.; Shiue C.-Y.; Kuo H.-C.; Jeng Y.-M.; Yen R.-F. |
| 臺大學術典藏 |
2018-09-10T07:20:53Z |
Oxygenated analogues of 1-[2-(diphenylmethoxy)ethyl]- and 1- [2- [bis (4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents
|
Lewis, D.B.;Matecka, D.;Zhang, Y.;Hsin, L.-W.;Dersch, C.M.;Stafford, D.;Glowa, J.R.;Rothman, R.B.;Rice, K.C.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T06:55:29Z |
Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates
|
Hsin, L.-W.;Wang, H.-P.;Kao, P.-H.;Lee, O.;Chen, W.-R.;Chen, H.-W.;Guh, J.-H.;Chan, Y.-L.;His, C.-P.;Yang, M.-S.;Li, T.-K.;Lee, C.-H.; LING-WEI HSIN; JIH-HWA GUH; TSAI-KUN LI |
| 臺大學術典藏 |
2018-09-10T05:45:17Z |
Novel radical synthesis of morphine fragments spiro[benzofuran-3(2H),4'-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline
|
Cheng, C.-Y.;Hsin, L.-W.;Liou, J.-P.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T05:45:17Z |
Synthesis of 1,4-bis [(17-normorphinyl)methyl]cubane, a morphine dimer linked by cubane
|
Cheng, C.-Y.;Hsin, L.-W.;Tao, P.-L.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T05:45:16Z |
N-Cubylmethyl substituted morphinoids as novel narcotic antagonists
|
Cheng, C.-Y.;Hsin, L.-W.;Lin, Y.-P.;Tao, P.-L.;Jong, T.-T.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T05:11:14Z |
Stereoselective synthesis of morphine fragments trans- and cis-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolines
|
Hsin, L.-W.;Chang, L.-T.;Chen, C.-W.;Hsu, C.-H.;Chen, H.-W.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T05:11:14Z |
The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats
|
Jutkiewicz, E.M.;Wood, S.K.;Houshyar, H.;Hsin, L.-W.;Rice, K.C.;Woods, J.H.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T05:11:13Z |
Asymmetric total synthesis of (-)-octahydro-1H-benzofuro[3,2-e] isoquinoline, a partial structure of morphine
|
Hsin, L.-W.;Chen, C.-W.;Chang, L.-T.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:42:54Z |
Synthesis of 3-[4-acyl-2-(1-methoxy-1-methylethyl)morpholin-3-yl]- benzonitriles as novel potassium channel openers
|
Lin, M.-S.;Hsin, L.-W.;Cheng, C.-Y.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:42:54Z |
Synthesis and opioid activity of 7-oxygenated 2,3,4,4a,5,6,7,7a-octahydro-1H-benzofuro[3,2-e]isoquinolin-9-ols
|
Cheng, C.-Y.;Hsin, L.-W.;Tsai, M.-C.;Schmidt, W.K.;Smith, C.;William Tam, S.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:37:18Z |
Synthesis of galanthamine analogs as acetylcholinesterase inhibitors via intramolecular heck cvclization
|
Liang, P.-H.;Hsin, L.-W.;Pong, S.-L.;Hsu, C.-H.;Cheng, C.-Y.; PI-HUI LIANG |
| 臺大學術典藏 |
2018-09-10T04:24:43Z |
A concise synthesis of (S)-(+)-1-(4-{2-[bis-(4-fluorophenyl)methoxy]-ethyl} piperazin-1-yl)-2-phenylpropan-2-ol dimaleate
|
Prisinzano, T.;Hsin, L.-W.;Folk, J.E.;Flippen-Anderson, J.L.;George, C.;Jacobson, A.E.;Rice, K.C.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:24:43Z |
Synthesis and dopamine transporter affinity of chiral 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2-hydroxypropyl)piperazines as potential cocaine abuse therapeutic agents
|
Hsin, L.-W.;Prisinzano, T.;Wilkerson, C.R.;Dersch, C.M.;Horel, R.;Jacobson, A.E.;Rothman, R.B.;Rice, K.C.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:24:43Z |
Synthesis of galanthamine analogs as acetylcholinesterase inhibitors via intramolecular heck cvclization
|
Liang, P.-H.;Hsin, L.-W.;Pong, S.-L.;Hsu, C.-H.;Cheng, C.-Y.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:04:49Z |
Selective reversible and irreversible ligands for the κ opioid receptor
|
Cheng, C.-Y.;Wu, S.-C.;Hsin, L.-W.;William Tam, S.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:04:48Z |
CRHR1 Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists
|
Hsin, L.-W.;Tian, X.;Webster, E.L.;Coop, A.;Caldwell, T.M.;Jacobson, A.E.;Chrousos, G.P.;Gold, P.W.;Habib, K.E.;Ayala, A.;Eckelman, W.C.;Contoreggi, C.;Rice, K.C.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:04:48Z |
Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: Chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy) ethyl]-4-(3-phenylpropyl)piperazine
|
Hsin, L.-W.;Dersch, C.M.;Baumann, M.H.;Stafford, D.;Glowa, J.R.;Rothman, R.B.;Jacobson, A.E.;Rice, K.C.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T04:04:48Z |
N-Arylated pyrrolidin-2-ones and morpholin-3-ones as potassium channel openers
|
Liang, P.-H.;Hsin, L.-W.;Cheng, C.-Y.; LING-WEI HSIN; PI-HUI LIANG |
| 臺大學術典藏 |
2018-09-10T04:04:48Z |
Synthesis of 1,4-dihydro-2-phenyl-4,4-bis(4-pyridinylmethyl)-2H-isoquinolin-3-one and related compounds as acetylcholine release enhancers
|
Lin, M.-S.;Hsin, L.-W.;Tsai, H.-B.;Tsai, M.-C.;Cheng, C.-Y.; LING-WEI HSIN |
| 臺大學術典藏 |
2018-09-10T03:41:21Z |
The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type 1
|
Tian, X.;Hsin, L.-W.;Webster, E.L.;Contoreggi, C.;Chrousos, G.P.;Gold, P.W.;Habib, K.;Ayala, A.;Eckelman, W.C.;Jacobson, A.E.;Rice, K.C.; LING-WEI HSIN |
