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Institution	Date	Title	Author
國家衛生研究院	2013-05	Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules	Wu, JM;Chen, CT;Coumar, MS;Lin, WH;Chen, ZJ;Hsu, JT;Peng, YH;Shiao, HY;Chu, CY;Wu, JS;Lin, CT;Chen, CP;Hsueh, CC;Chang, KY;Kao, LP;Huang, CY;Chao, YS;Wu, SY;Hsieh, HP;Chi, YH
國家衛生研究院	2013-05	Protein kinase inhibitor design by targeting the Asp-Phe-Gly (DFG) motif: The role of the DFG motif in the design of epidermal growth factor receptor inhibitors	Peng, YH;Shiao, HY;Tu, CH;Liu, PM;Hsu, JT;Amancha, PK;Wu, JS;Coumar, MS;Chen, CH;Wang, SY;Lin, WH;Sun, HY;Chao, YS;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院	2013-02-20	Parallel screening of Wild-Type and drug-resistant targets for anti-resistance neuraminidase inhibitors	Hsu, KC;Hung, HC;Horng, JT;Fang, MY;Chang, CY;Li, LT;Chen, IJ;Chen, YC;Chou, DL;Chang, CW;Hsieh, HP;Yang, JM;Hsu, JT
國家衛生研究院	2012-09	Anti-influenza drug discovery: Identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization	Yeh, JY;Coumar, MS;Shiao, HY;Lin, TJ;Lee, YC;Hung, HC;Ko, S;Kuo, FM;Fang, MY;Huang, YL;Hsu, JT;Yeh, TK;Shih, SR;Chao, YS;Horng, JT;Hsieh, HP
國家衛生研究院	2012-08	Development of an anti-influenza drug screening assay targeting nucleoproteins with tryptophan fluorescence quenching	Hung, HC;Liu, CL;Hsu, JT;Horng, JT;Fang, MY;Wu, SY;Ueng, SH;Wang, MY;Yaw, CW;Hou, MH
國家衛生研究院	2012-06-07	3-Phenyl-1H-5-pyrazolylamine-based derivatives as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Hsu, JT;Yeh, TK;Yen, SC;Chen, CT;Hsieh, SY;Hsu, T;Lu, CT;Chen, CH;Chou, LH;Chiu, CH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Lin, WH;Jiaang, WT
國家衛生研究院	2012-06	EGFR and myosin II inhibitors cooperate to suppress EGFR-T790M-mutant NSCLC cells	Chiu, HC;Chang, TY;Huang, CT;Chao, YS;Hsu, JT
國家衛生研究院	2012-02	Identification of BPR3P0128 as an Inhibitor of cap-snatching activities of influenza virus	Hsu, JT;Yeh, JY;Lin, TJ;Li, ML;Wu, MS;Hsieh, CF;Chou, YC;Tang, WF;Lau, KS;Hung, HC;Fang, MY;Ko, S;Hsieh, HP;Horng, JT
國家衛生研究院	2012-01	BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML	Lin, WH;Jiaang, WT;Chen, CW;Yen, KJ;Hsieh, SY;Yen, SC;Chen, CP;Chang, KY;Chang, CY;Chang, TY;Huang, YL;Yeh, TK;Chao, YS;Chen, CT;Hsu, JT
國家衛生研究院	2012-01	A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors	Lin, WH;Song, JS;Lien, TW;Chang, CY;Wu, SH;Huang, YW;Chang, TY;Fang, MY;Yen, KJ;Chen, CH;Chu, CY;Hsieh, HP;Chen, YR;Chao, YS;Hsu, JT
國家衛生研究院	2011-07	Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Lin, WH;Hsieh, SY;Yen, SC;Chen, CT;Yeh, TK;Hsu, T;Lu, CT;Chen, CP;Chen, CW;Chou, LH;Huang, YL;Cheng, AH;Chang, YI;Tseng, YJ;Yen, KR;Chao, YS;Hsu, JT;Jiaang, WT
中國醫藥大學	2011-07	Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis.	(Yang SJ); (Chen HM); 謝奇勳(Chi-Hsun Hsieh); (Hsu JT); (Yeh CN); (Yeh TS); (Hwang TL); (Jan YY)*; (Chen MF)
國家衛生研究院	2011-06-01	Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells	Chiu, HC;Chou, DL;Huang, CT;Lin, WH;Lien, TW;Yen, KJ;Hsu, JT
國家衛生研究院	2011-06	Synergistic inhibition of enterovirus 71 replication by interferon and rupintrivir	Hung, HC;Wang, HC;Shih, SR;Teng, IF;Tseng, CP;Hsu, JT
國家衛生研究院	2011-04-25	Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus	Wang, YJ;Pan, KL;Hsieh, TC;Chang, TY;Lin, WH;Hsu, JT
國家衛生研究院	2010-10-28	Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency	Wu, CH;Coumar, MS;Chu, CY;Lin, WH;Chen, YR;Chen, CT;Shiao, HY;Rafi, S;Wang, SY;Hsu, H;Chen, CH;Chang, CY;Chang, TY;Lien, TW;Fang, MY;Yeh, KC;Chen, CP;Yeh, TK;Hsieh, SH;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院	2010-10	Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists	Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院	2010-06-15	Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification	Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院	2010-02-25	Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives	Yeh, JY;Coumar, MS;Horng, JT;Shiao, HY;Kuo, FM;Lee, HL;Chen, IC;Chang, CW;Tang, WF;Tseng, SN;Chen, CJ;Shih, SR;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院	2010-01	BPR2-D2 targeting viral ribonucleoprotein complex-associated function inhibits oseltamivir-resistant influenza viruses	Shih, SR;Horng, JT;Poon, LL;Chen, TC;Yeh, JY;Hsieh, HP;Tseng, SN;Chiang, C;Li, WL;Chao, YS;Hsu, JT
國家衛生研究院	2009-11	Development of NS3/4A protease-based reporter assay suitable for efficiently assessing hepatitis C virus infection	Pan, KL;Lee, JC;Sung, HW;Chang, TY;Hsu, JT
中國醫藥大學	2009-08	Mechanism of salutary effects of estrogen on cardiac function following trauma-hemorrhage: Akt-dependent HO-1 up-regulation.	(Hsu JT); (Kan WH); (Hsieh CH); (Choudhry MA); (Bland KI); (Chaudry IH)*
國家衛生研究院	2009-07	Novel antiviral agent DTriP-22 targets RNA-dependent RNA polymerase of enterovirus 71	Chen, TC;Chang, HY;Lin, PF;Chern, JH;Hsu, JT;Chang, CY;Shih, SR
國家衛生研究院	2009-04-23	Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists	Lin, CH;Peng, YH;Coumar, MS;Chittimalla, SK;Liao, CC;Lyn, PC;Huang, CC;Lien, TW;Lin, WH;Hsu, JT;Cheng, JH;Chen, X;Wu, JS;Chao, YS;Lee, HJ;Juo, CG;Wu, SY;Hsieh, HP
國立臺灣大學	2009	Regulation of bacteriocin production in Ruminococcus flavefaciens C94.	Wang, WL; Wang, HT; Chen, CY; Liu, JR; Hsu, JT

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