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Institution	Date	Title	Author
國家衛生研究院	2014-11	Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent	Hsieh, HP;Kuo, CC;Chiu, JJ;Hsu, TA;Yeh, TK;Chen, CT
國家衛生研究院	2014-10-29	作為極光激酶抑制劑的稠合雙環嘧啶化合物	Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2014-10-21	化合物於製造治療病毒感染的藥物之用途	Hsieh, HP;Hsu, TA;Yeh, JY;Horng, JT;Shih, SR;Chang, SY;Chao, YS
國家衛生研究院	2014-10	Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma	Shiao, HY;Hsu, TA;Lin, WH;Yang, TT;Hsieh, HF;Chen, CT;Yeh, TK;Hsieh, HP
國家衛生研究院	2014-04-29	Quinoline compounds and their use for treating viral infection	Hsieh, HP;Hsu, TA;Yeh, JY;Chao, YS
國家衛生研究院	2014-04-21	作為蛋白質激酶抑制劑之吡唑化合物及噻唑化合物、其醫藥組成物及用途	Jiaang, WT;Hsu, TA;Lin, WH;Chao, YS
國家衛生研究院	2014-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2013-10-01	喹啉化合物及包含其之治療病毒感染之醫藥組成物	Hsieh, HP;Hsu, TA;Yeh, JY;Chao, YS
國家衛生研究院	2013-08-13	Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors	Hsieh, HP;Coumar, SM;Hsu, TA;Lin, WH;Chen, YR;Chao, YS
國家衛生研究院	2013-06	Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities	Lin, CH;Chang, TC;Das, A;Fang, MY;Hung, HC;Hsu, KC;Yang, JM;Von Itzstein, M;Mong, KKT;Hsu, TA;Lin, CC
國家衛生研究院	2013-02-11	作為酪胺酸激酶抑制劑之稠合雙環及多環嘧啶化合物	Hsieh, HP;Coumar, MS;Chao, YS;Hsu, TA;Lin, WH;Chen, YR
國家衛生研究院	2013-02	Resistance studies of a di-thiazol analogue, DBPR110, as a potential hepatitis C virus NS5A inhibitor in replicon systems	Lin, HM;Wang, JC;Hu, HS;Wu, PS;Wang, WH;Wu, SY;Yang, CC;Yeh, TK;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yueh, A
國家衛生研究院	2012-05-11	作為極光激酶抑制劑之稠合雙環嘧啶化合物	Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2012-04-11	咪唑啉酮及咪唑啉硫酮衍生物	Chern, JH;Hsu, TA;Kang, IJ;Wang, LW;Lee, CC;Lee, YC;Wu, YS;Hsu, SJ;Yueh, YA;Chao, YS
國家衛生研究院	2012-03-20	Fused bicyclic pyrimidine compounds as aurora kinase inhibitors	Hsieh, HP;Coumar, MS;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2012-03-01	C型肝炎病毒抑制劑	Chern, JH;Hsu, TA;Kang, IJ;Wang, LW;Lee, CC;Lee, YC;Chao, YS
國家衛生研究院	2012-02	Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents	Li, WT;Hwang, DR;Song, JS;Chen, CP;Chen, TW;Lin, CH;Chuu, JJ;Lien, TW;Hsu, TA;Huang, CL;Tseng, HY;Lin, CC;Lin, HL;Chang, CM;Chao, YS;Chen, CT
國家衛生研究院	2012-01	Resistance analysis and characterization of a thiazole analogue, BP008, as a potent hepatitis C virus NS5A inhibitor	Lin, HM;Wang, JC;Hu, HS;Wu, PS;Yang, CC;Wu, CP;Pu, SY;Hsu, TA;Jiaang, WT;Chao, YS;Chern, JH;Yeh, TK;Yueh, A
國家衛生研究院	2011-12	Development of a whole-cell screening system for evaluation of the human CYP1A2-mediated metabolism	Chu, CC;Pan, KL;Yao, HT;Hsu, TA
國家衛生研究院	2011-09-23	BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo	Hsieh, HP;Cheung, CHA;Lin, WH;Hsu, TA;Coumar, MS;Chao, YS;Chang, JY
國家衛生研究院	2011-08	BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells	Cheung, CH;Lin, WH;Hsu, TA;Hour, TC;Yeh, TK;Ko, S;Lien, TW;Coumar, MS;Liu, JF;Lai, WY;Shiao, HY;Lee, TR;Hsieh, HP;Chang, JY
國家衛生研究院	2011-07-26	Hepatitis C virus inhibitors	Wang, LW;Hsu, TA;Lee, YC;Kang, IJ;Lee, CC;Chao, YS;Chern, JH
國家衛生研究院	2011-07-11	抑制C型肝炎病毒感染之倍半帖內酯類化合物及其醫藥組成物	Hsieh, HP;Hsu, TA;Hwang, DR
國家衛生研究院	2011-06-21	抑制冠狀病毒之醫藥組合物	Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW
國家衛生研究院	2011-06-21	抑制冠狀病毒之醫藥組合物	Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW
國家衛生研究院	2011-06-21	抑制冠狀病毒之醫藥組合物	Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW
國家衛生研究院	2011-05-10	Imidazolidinone and imidazolidinethione derivatives	Chern, JH;Hsu, TA;Kang, IJ;Wang, LW;Lee, CC;Lee, YC;Wu, YS;Hsu, SJ;Yueh, YA;Chao, YS
國家衛生研究院	2011-04	Isatin-beta-thiosemicarbazones as potent herpes simplex virus inhibitors	Kang, IJ;Wang, LW;Hsu, TA;Yueh, A;Lee, CC;Lee, YC;Lee, CY;Chao, YS;Shih, SR;Chern, JH
國家衛生研究院	2011-03-01	Thiourea derivatives	Chern, JH;Hsu, TA;Kang, IJ;Wang, LW;Lee, CC;Lee, YC;Chao, YS
國家衛生研究院	2011-03	SAR studies of quinoline derivatives as novel anti-influenza agents	Ko,SK;Yeh, JY;Horng, JT;Hsu, TA;Hsieh HP
國家衛生研究院	2010-12-01	吲哚化合物	Hsieh, HP;Mahindroo, N;Hsu, TA;Huang, CF;Chen, X;Chao, YS
國家衛生研究院	2010-08-21	硫尿化合物及抑制C型肝炎病毒感染之方法	Chern, JH;Hsu, TA;Kang, IJ;Wang, LW;Lee, CC;Lee, YC;Chao, YS
國家衛生研究院	2010-08	Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models	Hsieh, HP;Chu, CY;Coumar, MS;Lin, WH;Chen, CT;Hsu, TA;Wu, SY;Chao, YS
國家衛生研究院	2009-11-01	Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors	Kang, IJ;Wang, LW;Hsu, SJ;Lee, CC;Lee, YC;Wu, YS;Yueh, A;Wang, JC;Hsu, TA;Chao, YS;Chern, JH
國家衛生研究院	2009-08-01	Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors	Kang, IJ;Wang, LW;Hsu, SJ;Lee, CC;Lee, YC;Wu, YS;Hsu, TA;Yueh, A;Chao, YS;Chern, JH
國家衛生研究院	2009-06-09	Treatment of coronavirus infection	Hsu, TA;Hsieh, HP;Chao, YS;Chen, CM;Jan, JT;Liu, HW
國家衛生研究院	2009-04-01	Design, synthesis, and anti-HCV activity of thiourea compounds	Kang, IJ;Wang, LW;Lee, CC;Lee, YC;Chao, YS;Hsu, TA;Chern, JH
國家衛生研究院	2009-03	Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors	Hsieh, HP;Coumar, MS;Lin, CW;Reddy, GR;Tsai, MT;Lin, WH;Hsu, TA;Wu, SY
國家衛生研究院	2008-12-11	吲哚化合物	Hsieh, HP;Mahindroo, N;Hsu, TA;Huang, CF;Chen, X;Chao, YS
國家衛生研究院	2008-11-11	Indole compounds	Hsieh, HP;Mahindroo, NH;Hsu, TA;Huang, CF;Chen, X;Chao, YS
國家衛生研究院	2008-02-11	一種抗病毒之醫藥組合物	Hsu, TA;Hsieh, HP;Juan, LJ;Chang, SY;Kuo, YH
國家衛生研究院	2007-03-01	用於治療黃病毒科病毒感染之醫藥組合物、套組、及包裝產品	Hsu, TA;Tsai, YC;Hwang, DR
國家衛生研究院	2006-08-01	抗腸病毒化合物	Chern, JH;Shia, KS;Shih, SR;Hsu, TA;Tai, CL
國家衛生研究院	2006-04-19	用於治療黃病毒科病毒感染之醫藥組合物、套組、及包裝產品	Hsu, TA;Tsai, YC;Hwang, DR
國家衛生研究院	2005-12-29	Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities	Mahindroo, N; Huang, CF; Peng, YH; Wang, CC; Liao, CC; Lien, TW; Chittimalla, SK; Huang, WJ; Chai, CH; Prakash, E; Chen, CP; Hsu, TA; Peng, CH; Lu, IL; Lee, LH; Chang, YW; Chen, WC; Chou, YC; Chen, CT; Goparaju, CMV; Chen, YS; Lan, SJ; Yu, MC; Chen, X; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院	2005-03	Promazine analogues as potential anti SARS-CoV drugs	Hsieh, HP;Wu, YS;Lu, PH;Chen, CM;Chao, YC;Jan, JT;Huei-Ru, L;Ma, SH;Chao, YS;Hsu, TA
國家衛生研究院	2005-03	Design, synthesis and sar of indole-based PPAR agonists	Hsieh, HP;Mahindroo, N;Coumar, MS;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Lin, YT;Lee, LH;Prakash, E;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Chao, YS
國家衛生研究院	2005-03	Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents	Hsieh, HP;Mahindroo, N;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Peng, YH;Lee, LH;Prakash, E;Chen, WC;Chang, YW;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Lan, SJ;Chao, YS
國家衛生研究院	2004-11-09	Anti-enterovirus compounds	Chern, JH;Shia, KS;Shih, SR;Hsu, TA;Tai, CL
國家衛生研究院	2004-05-17	Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidinies: a novel class of potent enterovirus inhibitors	Chern, JH; Shia, KS; Hsu, TA; Tai, CL; Lee, CC; Lee, YC; Chang, CS; Tseng, SN; Shih, SR

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