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Institution Date Title Author
國家衛生研究院 2025-07-14 Contribution of prostaglandin E2-induced neuronal excitation to drug resistance in glioblastoma countered by a novel blood-brain barrier crossing celecoxib derivative Shen, CJ;Chen, HC;Lin, CL;Thakur, A;Onuku, R;Chen, IC;Li, HY;Chang, KY;Chuang, JY;Yang, WB;Lin, HY;Shen, YR;Liou, JP;Chang, WC;Hsu, TI
國家衛生研究院 2025-01 Potential role of solid lipid curcumin particle (SLCP) as estrogen replacement therapy in mitigating TDP-43-related neuropathy in the mouse model of ALS disease Majumder, P;Hsu, TI;Hu, CJ;Huang, JK;Lee, YC;Hsieh, YC;Ahsan, A;Huang, CC
國家衛生研究院 2024-10 Exploring neuron-specific steroid synthesis and DHEAS therapy in Alzheimer's disease Lin, HY;Feng, YH;Kao, TJ;Chen, HC;Chen, GY;Ko, CY;Hsu, TI
國家衛生研究院 2024-04-17 Overcoming the blood-brain tumor barrier with docetaxel-loaded mesoporous silica nanoparticles for treatment of temozolomide-resistant glioblastoma Hsu, TI;Chen, YP;Zhang, RL;Chen, ZA;Wu, CH;Chang, WC;Mou, CY;Chan, HWH;Wu, SH
國家衛生研究院 2024-04-01 Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress Sharma, R;Chiang, YH;Chen, HC;Lin, HY;Yang, WB;Nepali, K;Lai, MJ;Chen, KY;Liou, JP;Hsu, TI
國家衛生研究院 2024-03 Mitochondrial mechanisms in temozolomide resistance: Un-raveling the complex interplay and therapeutic strategies in glioblastoma Li, HY;Feng, YH;Lin, CL;Hsu, TI
國家衛生研究院 2024-01-29 First-in-class dual EZH2-HSP90 inhibitor eliciting striking antiglioblastoma activity in vitro and in vivo Sharma, S;Wang, SA;Yang, WB;Lin, HY;Lai, MJ;Chen, HC;Kao, TY;Hsu, FL;Nepali, K;Hsu, TI;Liou, JP
國家衛生研究院 2024-01-18 Neurocutaneous melanosis with meningeal melanocytosis: A rare case of intracranial hypertension and cutaneous manifestations Chen, HC;Hsu, TI;Chao, TY;Yang, ST
國家衛生研究院 2023-11-07 Correlation of insulin-like growth factor 1 with cognitive functions in mild traumatic brain injury patients Ou, JC;Feng, YH;Chen, KY;Chiang, YH;Hsu, TI;Wu, CC
國家衛生研究院 2023-08-03 Dysregulated lipid metabolism in TMZ-resistant glioblastoma: Pathways, proteins, metabolites and therapeutic opportunities Kao, TJ;Lin, CL;Yang, WB;Li, HY;Hsu, TI
國家衛生研究院 2023-08 Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma Tseng, HJ;Banerjee, S;Qian, B;Lai, MJ;Wu, TY;Hsu, TI;Lin, TE;Hsu, KC;Chuang, KH;Liou, JP;Shih, JC
國家衛生研究院 2023-07-22 The complex role of eicosanoids in the brain: Implications for brain tumor development and therapeutic opportunities Chen, HC;Chang, WC;Chuang, JY;Chang, KY;Liou, JP;Hsu, TI
國家衛生研究院 2023-07-14 Metabolic reprogramming for acquiring therapeutic resistance in glioblastoma Hsu, TI
國家衛生研究院 2022-08-18 CCAAT/enhancer-binding protein delta regulates glioblastoma survival through catalase-mediated hydrogen peroxide clearance Lin, HY;Lim, SW;Hsu, TI;Yang, WB;Huang, CC;Tsai, YT;Chang, WC;Ko, CY
國家衛生研究院 2022-05 Allopregnanolone suppresses glioblastoma survival through decreasing DPYSL3 and S100A11 expression Feng, YH;Lim, SW;Lin, HY;Wang, SA;Hsu, SP;Kao, TJ;Ko, CY;Hsu, TI
國家衛生研究院 2022-03-25 Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation Tsai, YT;Lo, WL;Chen, PY;Ko, CY;Chuang, JY;Kao, TJ;Yang, WB;Chang, KY;Hung, CY;Kikkawa, U;Chang, WC;Hsu, TI
國家衛生研究院 2022-03-10 Regorafenib reverses temozolomide-induced CXCL12/CXCR4 signaling and triggers apoptosis mechanism in glioblastoma Chiang, IT;Liu, YC;Liu, HS;Ali, AAA;Chou, SY;Hsu, TI;Hsu, FT
國家衛生研究院 2022-02-02 HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells Wu, AC;Yang, WB;Chang, KY;Lee, JS;Liou, JP;Su, RY;Cheng, SM;Hwang, DY;Kikkawa, U;Hsu, TI;Wang, CY;Chang, WC;Chen, PY;Chuang, JY
國家衛生研究院 2021-12-20 L-selectin activation regulates Rho GTPase activity via Ca(+2) influx in Sertoli cell line, ASC-17D cells[Erratum:Biochemical and Biophysical Research Communications. 2020 May;525(4):1011-1017.] Limanjaya, I;Hsu, TI;Chuang, JY;Kao, TJ
國家衛生研究院 2021-09-28 Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells Yang, WB;Wu, AC;Hsu, TI;Liou, JP;Lo, WL;Chang, KY;Chen, PY;Kikkawa, U;Yang, ST;Kao, TJ;Chen, RM;Chang, WC;Ko, CY;Chuang, JY
國家衛生研究院 2021-08-20 17Beta-estradiol induces temozolomide resistance through NRF2-mediated redox homeostasis in glioblastoma Lin, HY;Liao, KH;Ko, CY;Chen, GY;Hsu, SP;Hung, CY;Hsu, TI
國家衛生研究院 2021-08-10 Vav2 is required for Netrin-1 receptor-class-specific spinal motor axon guidance Tsou, YS;Wang, CY;Chang, MY;Hsu, TI;Wu, MT;Wu, YH;Tsai, WL;Chuang, JY;Kao, TJ
國家衛生研究院 2021-05-31 NBM-BMX, an HDAC8 inhibitor, overcomes temozolomide resistance in glioblastoma multiforme by downregulating the beta-Cateninic-Myc/SOX2 pathway and upregulating p53-mediated MGMT inhibition Tsai, CY;Ko, HJ;Chiou, SJ;Lai, YL;Hou, CC;Javaria, T;Huang, ZY;Cheng, TS;Hsu, TI;Chuang, JY;Kwan, AL;Chuang, TH;Huang, CYF;Loh, JK;Hong, YR
國家衛生研究院 2021-03-16 Paxillin is required for proper spinal motor axon growth into the limb Tsai, WL;Chang, CJ;Wang, CY;Hsu, TI;Chang, MY;Wu, YH;Chang, PS;Lin, KL;Chuang, JY;Kania, A;Kao, TJ
國家衛生研究院 2020-04-24 Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma Yang, WB;Hsu, CC;Hsu, TI;Liou, JP;Chang, KY;Chen, PY;Liu, JJ;Yang, ST;Wang, JY;Yeh, SH;Chen, RM;Chang, WC;Chuang, JY
國家衛生研究院 2020-04-15 Betulinic acid-mediated tuning of PERK/CHOP signaling by Sp1 inhibition as a novel therapeutic strategy for glioblastoma Lo, WL;Hsu, TI;Yang, WB;Kao, TJ;Wu, MH;Huang, YN;Yeh, SH;Chuang, JY
國家衛生研究院 2020-04 17 beta-estradiol induces temozolomide resistance through redox optimization in glioblastoma Lin, HY;Hsu, TI;Ko, CY
國家衛生研究院 2020-04 ANGPTL4 induces TMZ resistance of glioblastoma by promoting cancer stemness enrichment via the EGFR/AKT/4E-BP1 cascade Tsai, YT;Ko, CY;Chang, WC;Hsu, TI
國家衛生研究院 2020-03-13 L-selectin activation regulates Rho GTPase activity via Ca(+2) influx in Sertoli cell line, ASC-17D cells Limanjaya, I;Hsu, TI;Chuang, JY;Kao, TJ
國家衛生研究院 2019-12-26 AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis Chen, TC;Chuang, JY;Ko, CY;Kao, TJ;Yang, PY;Yu, CH;Liu, MS;Hu, SL;Tsai, YT;Chan, H;Chang, WC;Hsu, TI
國家衛生研究院 2019-11-11 ANGPTL4 induces TMZ resistance of glioblastoma by promoting cancer stemness enrichment via the EGFR/AKT/4E-BP1 cascade Tsai, YT;Wu, AC;Yang, WB;Kao, TJ;Chuang, JY;Chang, WC;Hsu, TI
國家衛生研究院 2019-10-19 Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets Chien, CH;Chuang, JY;Yang, ST;Yang, WB;Chen, PY;Hsu, TI;Huang, CY;Lo, WL;Yang, KY;Liu, MS;Chu, JM;Chung, PH;Liu, JJ;Chou, SW;Chen, SH;Chang, KY
國家衛生研究院 2019-09-16 CYP17A1 maintains the survival of glioblastomas by regulating SAR1-Mediated endoplasmic reticulum health and redox homeostasis Lin, HY;Ko, CY;Kao, TJ;Yang, WB;Tsai, YT;Chuang, JY;Hu, SL;Yang, PY;Lo, WL;Hsu, TI
國家衛生研究院 2019-07 CCAAT/enhancer-binding protein delta regulates the stemness of glioma stem-like cells through activating PDGFA expression upon inflammatory stimulation Wang, SM;Lin, HY;Chen, YL;Hsu, TI;Chuang, JY;Kao, TJ;Ko, CY
國家衛生研究院 2018-08-04 Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress Wu, CC;Lee, PT;Kao, TJ;Chou, SY;Su, RY;Lee, YC;Yeh, SH;Liou, JP;Hsu, TI;Su, TP;Chuang, CK;Chang, WC;Chuang, JY
國家衛生研究院 2018-07-18 Dehydroepiandrosterone induces temozolomide resistance through modulating phosphorylation and acetylation of Sp1 in glioblastoma Yang, WB;Chuang, JY;Ko, CY;Chang, WC;Hsu, TI
國家衛生研究院 2017-11 Stress stimuli induce cancer-stemness gene expression via Sp1 activation leading to therapeutic resistance in glioblastoma Chang, KY;Huang, CT;Hsu, TI;Hsu, CC;Liu, JJ;Chuang, CK;Hung, JJ;Chang, WC;Tsai, KK;Chuang, JY
國家衛生研究院 2017-08-12 Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase Chang, KY;Hsu, TI;Hsu, CC;Tsai, SY;Liu, JJ;Chou, SW;Liu, MS;Liou, JP;Ko, CY;Chen, KY;Hung, JJ;Chang, WC;Chuang, CK;Kao, TJ;Chuang, JY
國家衛生研究院 2017-05-22 Upregulation of CYP17A1 by Sp1-mediated DNA demethylation confers temozolomide resistance through DHEA-mediated protection in glioma Chuang, JY;Lo, WL;Ko, CY;Chou, SY;Chen, RM;Chang, KY;Hung, JJ;Su, WC;Chang, WC;Hsu, TI
國家衛生研究院 2017-05-06 MDM2 degrades deacetylated nucleolin through ubiquitination to promote glioma stem-like cell enrichment for chemotherapeutic resistance Ko, CY;Lin, CH;Chuang, JY;Chang, WC;Hsu, TI
國家衛生研究院 2016-11-18 Suberoylanilide hydroxamic acid represses glioma stem-like cells Hsu, CC;Chang, WC;Hsu, TI;Liu, JJ;Yeh, SH;Wang, JY;Liou, JP;Ko, CY;Chang, KY;Chuang, JY
國家衛生研究院 2016-04 Positive feedback regulation between IL10 and EGFR promotes lung cancer formation Hsu, TI;Wang, YC;Hung, CY;Yu, CH;Su, WC;Chang, WC;Hung, JJ
臺北醫學大學 2015 A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy Hsu, TI;Chen, YJ;Hung, CY;Wang, YC;Lin, SJ;Su, WC;Lai, MD;Kim, SY;Wang, Q;Qian, K;Goto, M;Zhao, Y;Kashiwada, Y;Lee, KH;
臺北醫學大學 2015 A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy Hsu, TI;Chen, YJ;Hung, CY;Wang, YC;Lin, SJ;Su, WC;Lai, MD;Kim, SY;Wang, Q;Qian, K;Goto, M;Zhao, Y;Kashiwada, Y;Lee, KH;
臺北醫學大學 2014 MicroRNA-296-5p (miR-296-5p) functions as a tumor suppressor in prostate cancer by directly targeting Pin1 Lee, KH;Lin, FC;Hsu, TI;Lin, JT;Guo, JH;Tsai, CH;Lee, YC;Lee, YC;Chen, CL;Hsiao, M;Lu, PJ
臺北醫學大學 2014 MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy Hsu, TI;Lin, SC;Lu, PS;Chang, WC;Hung, CY;Yeh, YM;Su, WC;
臺北醫學大學 2014 MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy Hsu, TI;Lin, SC;Lu, PS;Chang, WC;Hung, CY;Yeh, YM;Su, WC;
臺北醫學大學 2014 Phosphorylation of p300 increases its protein degradation to enhance the lung cancer progression Wang, SA;Hung, CY;Chuang, JY;Chang, WC;Hsu, TI;Hung, JJ
臺北醫學大學 2014 Nucleolin enhances internal ribosomal entry site (IRES)-mediated translation of Sp1 in tumorigenesis article type Hung, CY;Yang, WY;Wang, SA;Hsu, TI;Chang, WC;Hung, JJ
臺北醫學大學 2014 Nucleolin enhances internal ribosomal entry site (IRES)-mediated translation of Sp1 in tumorigenesis article type Hung, CY;Yang, WY;Wang, SA;Hsu, TI;Chang, WC;Hung, JJ

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