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Showing items 1-25 of 45 (2 Page(s) Totally)
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| 國家衛生研究院 |
2024-07-04 |
Development of a humanized antibody targeting extracellular HSP90alpha to suppress endothelial-mesenchymal transition-enhanced tumor growth of pancreatic adenocarcinoma cells
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Fan, CS;Hung, HC;Chen, CC;Chen, LL;Ke, YY;Yeh, TK;Huang, CT;Chang, TY;Yen, KJ;Chen, CH;Chua, KV;Hsu, JTA;Huang, TS |
| 國家衛生研究院 |
2024-04-09 |
Discovery of a long half-life AURKA inhibitor to treat MYC-amplified solid tumors as a monotherapy and in combination with everolimus
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Chang, CP;Yeh, TK;Chen, CT;Wang, WP;Chen, YT;Tsai, CH;Chen, YF;Ke, YY;Wang, JY;Chen, CP;Hsieh, TC;Wu, MH;Huang, CL;Chen, YP;Zhuang, H;Chi, YH |
| 國家衛生研究院 |
2023-10-05 |
Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease
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Yao, CH;Shen, ZQ;Rajan, YC;Huang, YW;Lin, CY;Song, JS;Shiao, HY;Ke, YY;Fan, YS;Tsai, CH;Yeh, TK;Tsai, TF;Lee, JC |
| 國家衛生研究院 |
2022-12-05 |
Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation
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Kuppusamy, R;Hsu, YT;Ke, YY;Chang, PW;Chang, YC;Chang, HF;Wang, PC;Lin, YH;Huang, YC;Yeh, TK;Chuang, JY;Loh, HH;Shih, C;Chen, CT;Yeh, SH;Ueng, SH |
| 國家衛生研究院 |
2022-06-02 |
Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone
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Lin, SY;Tien, YW;Ke, YY;Chang, YC;Chang, HF;Ou, LC;Law, PY;Xi, JH;Tao, PL;Loh, HH;Chao, YS;Shih, C;Chen, CT;Yeh, SH;Ueng, SH |
| 國家衛生研究院 |
2021-10 |
Chemoproteomic profiling reveals cellular targets of nitro-fatty acids
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Fang, MY;Huang, KH;Tu, WJ;Chen, YT;Pan, PY;Hsiao, WC;Ke, YY;Tsou, LK;Zhang, MM |
| 國家衛生研究院 |
2021-08-01 |
Characterization of a mutated KCNJ5 gene, G387R, in unilateral primary aldosteronism
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Chueh, JS;Peng, KY;Wu, VC;Shuo-Meng, W;Chieh-Kai, C;Chen, YM;Ke, YY;Pan, CY;Liao, HW |
| 國家衛生研究院 |
2021-05-19 |
Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins
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Chi, YH;Yeh, TK;Ke, YY;Lin, WH;Tsai, CH;Wang, WP;Chen, YT;Su, YC;Wang, PC;Chen, YF;Wu, ZW;Yeh, JY;Hung, MC;Wu, MH;Wang, JY;Chen, CP;Song, JS;Shih, C;Chen, CT;Chang, CP |
| 國家衛生研究院 |
2021-03-30 |
A highly selective and potent CXCR4 antagonist for hepatocellular carcinoma treatment
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Song, JS;Chang, CC;Wu, CH;Dinh, TK;Jan, JJ;Huang, KW;Chou, MC;Shiue, TY;Yeh, KC;Ke, YY;Yeh, TK;Ta, YNN;Lee, CJ;Huang, JK;Sung, YC;Shia, KS;Chen, Y |
| 國家衛生研究院 |
2020-10-08 |
Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery
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Tsou, LK;Yeh, SH;Ueng, SH;Chang, CP;Song, JS;Wu, MH;Chang, HF;Chen, SR;Shih, C;Chen, CT;Ke, YY |
| 國家衛生研究院 |
2020-08-20 |
Discovery of M protease inhibitors encoded by SARS-CoV-2
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Hung, HC;Ke, YY;Huang, SY;Huang, PN;Kung, YA;Chang, TY;Yen, KJ;Peng, TT;Chang, SE;Huang, CT;Tsai, YR;Wu, SH;Lee, SJ;Lin, JH;Liu, BS;Sung, WC;Shih, SR;Chen, CT;Hsu, JT |
| 國家衛生研究院 |
2020-08 |
BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification
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Chi, YH;Chang, CP;Ke, YY;Lin, WH;Wang, WP;Tsai, CH;Chen, YT;Su, YJ;Hung, MC;Wu, ZW;Wu, MH;Yeh, TK;Chen, CP;Song, JS;Chen, CT;Shih, C |
| 國家衛生研究院 |
2020-05-23 |
Repurposing old drugs as antiviral agents for coronaviruses
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Yang, CW;Peng, TT;Hsu, HY;Lee, YZ;Wu, SH;Lin, WH;Ke, YY;Hsu, TA;Yeh, TK;Huang, WZ;Lin, JH;Sytwu, HK;Chen, CT;Lee, SJ |
| 國家衛生研究院 |
2020-05-15 |
Artificial intelligence approach fighting COVID-19 with repurposing drugs
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Ke, YY;Peng, TT;Yeh, TK;Huang, WZ;Chang, SE;Wu, SH;Hung, HC;Hsu, TA;Lee, SJ;Song, JS;Lin, WH;Chiang, TJ;Lin, JH;Sytwu, HK;Chen, CT |
| 國家衛生研究院 |
2019-10 |
Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer
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Hsieh, HP;Chang, JY;Yeh, CT;Lin, SY;Ke, YY;Lin, WH;Hsu, TA;Wu, SY;Yeh, TK |
| 國家衛生研究院 |
2019-09-27 |
Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer
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Lin, SY;Chang Hsu, Y;Peng, YH;Ke, YY;Lin, WH;Sun, HY;Shiao, HY;Kuo, FM;Chen, PY;Lien, TW;Chen, CH;Chu, CY;Wang, SY;Yeh, KC;Chen, CP;Hsu, TA;Wu, SY;Yeh, TK;Chen, CT;Hsieh, HP |
| 國家衛生研究院 |
2019-07 |
Dual Kit/Aur inhibitors as chemosensitizing agents for the treatment of melanoma: Design, synthesis, docking studies and functional investigation
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Quattrini, L;Coviello, V;Sartini, S;Di Desidero, T;Orlandi, P;Ke, YY;Liu, KL;Hsieh, HP;Bocci, G;La Motta, C |
| 國家衛生研究院 |
2019-07 |
An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer
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Chang, CP;Ke, YY;Lin, WH;Jhuo, DH;Wang, WP;Tsai, CH;Chen, YT;Su, YJ;Hung, MC;Wu, ZW;Kuo, PC;Yeh, TK;Chen, CP;Song, JS;Chen, CT;Shih, C;Chi, YH |
| 國家衛生研究院 |
2019-04-01 |
The in vivo antinociceptive and mu-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone
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Lin, SY;Kuo, YH;Tien, YW;Ke, YY;Chang, WT;Chang, HF;Ou, LC;Law, PY;Xi, JH;Tao, PL;Loh, HH;Chao, YS;Shih, C;Chen, CT;Yeh, SH;Ueng, SH |
| 國家衛生研究院 |
2018-07 |
Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer
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Kuo, CC;Chang, JY;Hsieh, HP;Kung, HJ;Chang, HH;Huang, CH;Kuo, CC;Ke, YY |
| 國家衛生研究院 |
2018-05-10 |
Design and synthesis of BPR1K653 derivatives targeting the back pocket of Aurora kinases for selective isoform inhibition
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Ke, YY;Chang, CP;Lin, WH;Tsai, CH;Chiu, IC;Wang, WP;Wang, PC;Chen, PY;Lin, WH;Chang, CF;Kuo, PC;Song, JS;Shih, C;Hsieh, HP;Chi, YH |
| 國家衛生研究院 |
2018-04-25 |
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors
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La Pietra, V;Sartini, S;Botta, L;Antonelli, A;Ferrari, SM;Fallahi, P;Moriconi, A;Coviello, V;Quattrini, L;Ke, YY;Hsing-Pang, H;Da Settimo, F;Novellino, E;La Motta, C;Marinelli, L |
| 國家衛生研究院 |
2018-02-08 |
Development of stem-cell-mobilizing agents targeting CXCR4 receptor for peripheral blood stem cell transplantation and beyond
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Wu, CH;Song, JS;Kuan, HH;Wu, SH;Chou, MC;Jan, JJ;Tsou, LK;Ke, YY;Chen, CT;Yeh, KC;Wang, SY;Yeh, TK;Tseng, CT;Huang, CL;Wu, MH;Kuo, PC;Lee, CJ;Shia, KS |
| 國家衛生研究院 |
2017-08-02 |
Harnessing CXCR4 antagonists in stem cell mobilization, HIV infection, ischemic diseases, and oncology
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Tsou, LK;Huang, YH;Song, JS;Ke, YY;Huang, JK;Shia, KS |
| 國家衛生研究院 |
2017-07 |
Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors
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Yeh, TK;Kuo, CC;Lee, YZ;Ke, YY;Chu, KF;Hsu, HY;Chang, HY;Liu, YW;Song, JS;Yang, CW;Lin, LM;Sun, MW;Wu, SH;Kuo, PC;Shih, C;Chen, CT;Tsou, LK;Lee, SJ |
Showing items 1-25 of 45 (2 Page(s) Totally)
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