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Institution Date Title Author
國家衛生研究院 2025-04-29 Identifying rare germline variants associated with metastatic prostate cancer through an extreme phenotype study Lin, YY;Noghabi, HS;Volik, S;Bell, R;Sar, F;Haegert, A;Chung, HC;Fazli, L;Oo, HZ;Daugaard, M;Kuo, MH;Hsu, SC;Imeda, EL;Zanettini, C;Queiroz, L;Schlotmann, B;Gheybi, K;Cooper, C;Kote-Jarai, Z;Eeles, R;Kung, HJ;Marchionni, L;Weischenfeldt, J;Miller, KD;Rabinowitz, A;Wang, Y;Zhang, HF;Sorensen, PH;Carey, MS;Gleave, M;Hayes, VM;Gibson, WT;Collins, CC
國家衛生研究院 2025-04-21 KDM4C works in concert with GATA1 to regulate heme metabolism in head and neck squamous cell carcinoma Wu, MJ;Yang, SM;Fang, WK;Chen, TJ;Wu, CY;Hsu, YJ;Shen, CE;Cheng, YC;Hsieh, WC;Yuh, CH;Yang, MH;Kung, HJ;Wang, WC
國家衛生研究院 2024-10-01 Hypoxia-induced long noncoding RNA HIF1A-AS2 regulates stability of MHC class I protein in head and neck cancer Liao, TT;Chen, YH;Li, ZY;Hsiao, AC;Huang, YL;Hao, RX;Tai, SK;Chu, PY;Shih, JW;Kung, HJ;Yang, MH
國家衛生研究院 2024-08-29 Hydrogen sulfide coordinates glucose metabolism switch through destabilizing tetrameric pyruvate kinase M2 Wang, RH;Chen, PR;Chen, YT;Chen, YC;Chu, YH;Chien, CC;Chien, PC;Lo, SY;Wang, ZL;Tsou, MC;Chen, SY;Chiu, GS;Chen, WL;Wu, YH;Wang, LHC;Wang, WC;Lin, SY;Kung, HJ;Wang, LH;Cheng, HC;Lin, KT
國家衛生研究院 2024-08-16 The miRNAs 203a/210-3p/5001-5p regulate the androgen/androgen receptor/YAP-induced migration in prostate cancer cells Huo, C;Kuo, YY;Lin, CY;Shiah, SG;Li, CY;Huang, SP;Chen, JK;Wang, WC;Kung, HJ;Chuu, CP
國家衛生研究院 2023-09-15 REST-repressed lncRNA LINC01801 induces neuroendocrine differentiation in prostate cancer via transcriptional activation of autophagy Chang, CH;Cheng, TY;Yeh, WW;Luo, YL;Campbell, M;Kuo, TC;Shen, TW;Hong, YC;Tsai, CH;Peng, YC;Pan, CC;Yang, MH;Shih, JC;Kung, HJ;Huang, WJ;Chang, PC;Lin, TP
國家衛生研究院 2023-09-01 Method and composition for decreasing the pschotomimetic and addictive disorder of ketamine Chen, HH;Kung, HJ
國家衛生研究院 2023-04 Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer Hung, CL;Liu, HH;Fu, CW;Yeh, HH;Hu, TL;Kuo, ZK;Lin, YC;Jhang, MR;Hwang, CS;Hsu, HC;Kung, HJ;Wang, LY
國家衛生研究院 2023-03-21 Method and composition for decreasing the psychotomimetic side effect and addictive disorder of ketamine Chen, HH;Kung, HJ
國家衛生研究院 2022-05-09 Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer Liu, JS;Fang, WK;Yang, SM;Wu, MC;Chen, TJ;Chen, CM;Lin, TY;Liu, KL;Wu, CM;Chen, YC;Chuu, CP;Wang, LY;Hsieh, HP;Kung, HJ;Wang, WC
國家衛生研究院 2022-05-05 TEAD4 as an oncogene and a mitochondrial modulator Hsu, SC;Lin, CY;Lin, YY;Collins, CC;Chen, CL;Kung, HJ
國家衛生研究院 2022-03 Inhibition of KDM4C/c-Myc/LDHA signalling axis suppresses prostate cancer metastasis via interference of glycolytic metabolism Lin, CY;Wang, BJ;Fu, YK;Huo, C;Wang, YP;Chen, BC;Liu, WY;Tseng, JC;Jiang, SS;Sie, ZL;Tsai, KK;Yuh, CH;Wang, WC;Kung, HJ;Chuu, CP
國家衛生研究院 2021-12-14 Targeting mitochondrial OXPHOS and their regulatory signals in prostate cancers Chen, C;Lin, C;Kung, HJ
國家衛生研究院 2021-11 Human iPSC-derived neurons as a platform for deciphering the mechanisms behind brain aging Chao, CC;Shen, PW;Tzeng, TY;Kung, HJ;Tsai, TF;Wong, YH
國家衛生研究院 2021-08-12 Prognostic significance of o-glcnac and PKM2 in hormone receptor-positive and HER2-nonenriched breast cancer Kuo, WL;Tseng, LL;Chang, CC;Chen, CJ;Cheng, ML;Cheng, HH;Wu, MJ;Chen, YL;Chang, RT;Tang, HY;Hsu, YC;Lin, WJ;Kao, CY;Hsieh, WP;Kung, HJ;Wang, WC
國家衛生研究院 2021-07-15 Arginine signaling and cancer metabolism Chen, CL;Hsu, SC;Ann, DK;Yen, Y;Kung, HJ
國家衛生研究院 2021-06-26 Targeting KDM4B that coactivates c-Myc-regulated metabolism to suppress tumor growth in castration- resistant prostate cancer Wu, MJ;Chen, CJ;Lin, TY;Liu, YY;Tseng, LL;Cheng, ML;Chuu, CP;Tsai, HK;Kuo, WL;Kung, HJ;Wang, WC
國家衛生研究院 2021-06-04 Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes Hsu, SC;Chen, CL;Cheng, ML;Chu, CY;Changou, CA;Yu, YL;Yeh, SD;Kuo, TC;Kuo, CC;Chuu, CP;Li, CF;Wang, LH;Chen, HW;Yen, Y;Ann, DK;Wang, HJ;Kung, HJ
國家衛生研究院 2021-05-05 Long non-coding rnas as functional codes for oral cancer: Translational potential, progress and promises Lei, CS;Kung, HJ;Shih, JW
國家衛生研究院 2021-04-23 Arginine is an epigenetic regulator targeting TEAD4 to modulate OXPHOS in prostate cancer cells Chen, CL;Hsu, SC;Chung, TY;Chu, CY;Wang, HJ;Hsiao, PW;Yeh, SD;Ann, DK;Yen, Y;Kung, HJ
國家衛生研究院 2021-01-25 Genome-wide CRISPR/Cas9 knockout screening uncovers a novel inflammatory pathway critical for resistance to arginine-deprivation therapy Chu, CY;Lee, YC;Hsieh, CH;Yeh, CT;Chao, TY;Chen, PH;Lin, IH;Hsieh, TH;Shih, JW;Cheng, CH;Chang, CC;Lin, PS;Huang, YL;Chen, TM;Yen, Y;Ann, DK;Kung, HJ
中山醫學大學 2021 Targeting KDM4B that coactivates c-Myc-regulated metabolism to suppress tumor growth in castration- resistant prostate cancer Wu, MJ; Chen, CJ; Lin, TY; Liu, YY; Tseng, LL; Cheng, ML; Chuu, CP; Tsai, HK; Kuo, WL; Kung, HJ; Wang, WC
中山醫學大學 2021 Prognostic Significance of O-GlcNAc and PKM2 in Hormone Receptor-Positive and HER2-Nonenriched Breast Cancer Kuo, WL; Tseng, LL; Chang, CC; Chen, CJ; Cheng, ML; Cheng, HH; Wu, MJ; Chen, YL; Chang, RT; Tang, HY; Hsu, YC; Lin, WJ; Kao, CY; Hsieh, WP; Kung, HJ; Wang, WC
國家衛生研究院 2020-09-21 Targeting the histone demethylase PHF8-mediated PKCalpha-Src-PTEN axis in HER2-negative gastric cancer Tseng, LL;Cheng, HH;Yeh, TS;Huang, SC;Syu, YY;Chuu, CP;Yuh, CH;Kung, HJ;Wang, WC
國家衛生研究院 2020-05 Signaling in and out: Long-noncoding RNAs in tumor hypoxia Kuo, TC;Kung, HJ;Shih, JW
國家衛生研究院 2020-03-31 Muscle atrophy-related myotube-derived exosomal microRNA in neuronal dysfunction: Targeting both coding and long noncoding RNAs Yang, CP;Yang, WS;Wong, YH;Wang, KH;Teng, YC;Chang, MH;Liao, KH;Nian, FS;Chao, CC;Tsai, JW;Hwang, WL;Lin, MW;Tzeng, TY;Wang, PN;Campbell, M;Chen, LK;Tsai, TF;Chang, PC;Kung, HJ
國家衛生研究院 2020-02 lncRNA UBA6-AS1 participates in the integrated stress response of breast cancer Wu, YZ;Chen, YH;Cheng, CT;Chi, KV;Kuo, TC;Kung, HJ;Ann, DK;Kuo, CY
國家衛生研究院 2020-01 Cancer-derived succinate promotes macrophage polarization and cancer metastasis via succinate receptor Wu, JY;Huang, TW;Hsieh, YT;Wang, YF;Yen, CC;Lee, GL;Yeh, CC;Peng, YJ;Kuo, YY;Wen, HT;Lin, HC;Hsiao, CW;Wu, KK;Kung, HJ;Hsu, YJ;Kuo, CC
國家衛生研究院 2019-11-13 Histone demethylase KDM4C stimulates the proliferation of prostate cancer cells via activation of AKT and c-Myc Lin, CY;Wang, BJ;Chen, BC;Tseng, JC;Jiang, SS;Tsai, KK;Shen, YY;Yuh, CH;Sie, ZL;Wang, WC;Kung, HJ;Chuu, CP
國家衛生研究院 2019-08-29 Dysregulation of cystathionine γ-lyase promotes prostate cancer progression and metastasis Wang, YH;Huang, JT;Chen, WL;Wang, RH;Kao, MC;Pan, YR;Chan, SH;Tsai, KW;Kung, HJ;Lin, KT;Wang, LH
國家衛生研究院 2019-03-15 Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation Chen, TJ;Wang, HJ;Liu, JS;Cheng, HH;Hsu, SC;Wu, MC;Lu, CH;Wu, YF;Wu, JW;Liu, YY;Kung, HJ;Wang, WC
國家衛生研究院 2019-01-25 KDM4B is a coactivator of c-Jun and involved in gastric carcinogenesis Wu, MC;Cheng, HH;Yeh, TS;Li, YC;Chen, TJ;Sit, WY;Chuu, CP;Kung, HJ;Chien, S;Wang, WC
國家衛生研究院 2018-10-26 Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction Cheng, CT;Qi, Y;Wang, YC;Chi, KK;Chung, Y;Ouyang, C;Chen, YR;Oh, ME;Sheng, X;Tang, Y;Liu, YR;Lin, HH;Kuo, CY;Schones, D;Vidal, CM;Chu, JC;Wang, HJ;Chen, YH;Miller, KM;Chu, P;Yen, Y;Jiang, L;Kung, HJ;Ann, DK
國家衛生研究院 2018-10-01 HOTAIR is a REST-regulated lncRNA that promotes neuroendocrine differentiation in castration resistant prostate cancer Chang, YT;Lin, TP;Tang, JT;Campbell, M;Luo, YL;Lu, SY;Yang, CP;Cheng, TY;Chang, CH;Liu, TT;Lin, CH;Kung, HJ;Pan, CC;Chang, PC
國家衛生研究院 2018-08 KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC Wang, HJ;Pochampalli, M;Wang, LY;Zou, JX;Li, PS;Hsu, SC;Wang, BJ;Huang, SH;Yang, P;Yang, JC;Chu, CY;Hsieh, CL;Sung, SY;Li, CF;Tepper, CG;Ann, DK;Gao, AC;Evans, CP;Izumiya, Y;Chuu, CP;Wang, WC;Chen, HW;Kung, HJ
國家衛生研究院 2018-07 Blockage of EGFR signaling repurposes tumor metabolism through suppression of glycolysis and Kreb cycle in head and neck cancer Kuo, CC;Chang, JY;Hsieh, HP;Kung, HJ;Chang, HH;Huang, CH;Kuo, CC;Ke, YY
國家衛生研究院 2018-01-29 In vitro SUMOylation assay to study SUMO E3 ligase activity Yang, WS;Campbell, M;Kung, HJ;Chang, PC
國家衛生研究院 2017-11 EZH2-mediated upregulation of ROS1 oncogene promotes oral cancer metastasis Shih, CH;Chang, YJ;Huang, WC;Jang, TH;Kung, HJ;Wang, WC;Yang, MH;Lin, MC;Huang, SF;Chou, SW;Chang, E;Chiu, H;Shieh, TY;Chen, YJ;Wang, LH;Chen, L
國家衛生研究院 2017-08-08 Long non-coding RNA and tumor hypoxia: New players ushered toward an old arena Shih, JW;Kung, HJ
國家衛生研究院 2017-06-22 Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1alpha co-activator driving oral cancer progression Shih, JW;Chiang, WF;Wu, ATH;Wu, MH;Wang, LY;Yu, YL;Hung, YW;Wang, WC;Chu, CY;Hung, CL;Changou, CA;Yen, Y;Kung, HJ
國家衛生研究院 2017-03-03 REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer Chang, YT;Lin, TP;Campbell, M;Pan, CC;Lee, SH;Lee, HC;Yang, MH;Kung, HJ;Chang, PC
國家衛生研究院 2016-11 Silencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy Wang, J;Wang, H;Wang, LY;Cai, DM;Duan, Z;Zhang, Y;Chen, P;Zou, JX;Xu, JZ;Chen, XB;Kung, HJ;Chen, HW
國家衛生研究院 2016-09-13 KDM4A coactivates E2F1 to regulate the PDK-dependent metabolic switch between mitochondrial oxidation and glycolysis Wang, LY;Hung, CL;Chen, YR;Yang, JC;Wang, J;Campbell, M;Izumiya, Y;Chen, HW;Wang, WC;Ann, DK;Kung, HJ
國家衛生研究院 2016-09 Metabolic stress-induced phosphorylation of KAP1 Ser473 blocks mitochondrial fusion in breast cancer cells Cheng, CT;Kuo, CY;Ouyang, C;Li, CF;Chung, YY;Chan, D;Kung, HJ;Ann, DK
國家衛生研究院 2016-06 HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity Kuo, CY;Cheng, CT;Hou, P;Lin, YP;Ma, H;Chung, Y;Chi, K;Chen, Y;Li, W;Kung, HJ;Ann, DK
國家衛生研究院 2016-06 Rapid discovery of functional small molecule ligands against proteomic targets through library-against-library screening Wu, CY;Wang, DH;Wang, X;Dixon, SM;Meng, L;Ahadi, S;Enter, DH;Chen, CY;Kato, J;Leon, LJ;Ramirez, LM;Maeda, Y;Reis, CF;Ribeiro, B;Weems, B;Kung, HJ;Lam, KS
國家衛生研究院 2016-05 REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling Lin, TP;Chang, YT;Lee, SY;Campbell, M;Wang, TC;Shen, SH;Chung, HJ;Chang, YH;Chiu, AW;Pan, CC;Lin, CH;Chu, CY;Kung, HJ;Cheng, CY;Chang, PC
國家衛生研究院 2015-12-04 Non-coding RNAs in castration-resistant prostate cancer: Regulation of androgen receptor signaling and cancer metabolism Shih, JW;Wang, LY;Hung, CL;Kung, HJ;Hsieh, CL
國家衛生研究院 2015-07-10 Akt3 promotes prostate cancer proliferation cells through regulation of Akt, B-Raf & TSC1/TSC2 Lin, HP;Lin, CY;Huo, C;Jan, YJ;Tseng, JC;Jiang, SS;Kuo, YY;Chen, SC;Wang, CT;Chan, TM;Liou, JY;Wang, J;Chang, WW;Chang, CH;Kung, HJ;Chuu, CP
國家衛生研究院 2015-04-30 Elevation of soluble guanylate cyclase suppresses proliferation and survival of human breast cancer cells Wen, HC;Chuu, CP;Chen, CY;Shiah, SG;Kung, HJ;King, KL;Su, LC;Chang, SC;Chang, CH

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