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Institution Date Title Author
國立臺灣大學 2014 YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK Chang, Ling-Chu; Lin, Hui-Yi; Tsai, Meng-Tung; Chou, Ruey-Hwang; Lee, Fang-Yu; Teng, Che-Ming; Hsieh, Min-Tsang; Hung, Hsin-Yi; Huang, Li-Jiau; Yu, Yung-Luen; Kuo, Sheng-Chu; 鄧哲明
國立成功大學 2013-09-15 Design, synthesis, and mechanism of action of 2-(3-hydroxy-5-methoxyphenyl)-6-pyrrolidinylquinolin-4-one as a potent anticancer lead Cheng, Yung-Yi; Liu, Chin-Yu; Tsai, Meng-Tung; Lin, Hui-Yi; Yang, Jai-Sing; Wu, Tian-Shung; Kuo, Sheng-Chu; Huang, Li-Jiau; Lee, Kuo-Hsiung
國立成功大學 2013-05 The novel carboxamide analog ITR-284 induces caspase-dependent apoptotic cell death in human hepatocellular and colorectal cancer cells Liao, Yu-Ren; Lu, Chi-Cheng; Lai, Kuang-Chi; Yang, Jai-Sing; Kuo, Sheng-Chu; Wen, Yen-Fang; Fushiya, Shinji; Wu, Tian-Shung
國立成功大學 2013-03 AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells Lin, Chingju; Tsai, Shih-Chang; Tseng, Michael T.; Peng, Shu-Fen; Kuo, Sheng-Chu; Lin, Meng-Wei; Hsu, Yuan-Man; Lee, Miau-Rong; Amagaya, Sakae; Huang, Wen-Wen; Wu, Tian-Shung; Yang, Jai-Sing
大葉大學 2012-11-25 nti-heat-labile enterotoxin phytochemicals and its derivatives from the plants of Zingiberaceae family C, hen Jaw-Chyun;Huang, Li-Jiau;Kuo, Sheng-Chu;Chang, Chih-Shiang;Haung, Yu-Fen;Ho, Tin-Yun;Hsiang, Chien-Yun
國立成功大學 2012-03 The role of mitochondria-mediated intrinsic death pathway in gingerdione derivative I6-induced neuronal apoptosis Lin, Chia-Ho; Chen, Po-See; Kuo, Sheng-Chu; Huang, Li-Jiau; Gean, Po-Wu; Chiu, Ted-H
國立臺灣大學 2012 Asperjinone, a Nor-Neolignan, and Terrein, a Suppressor of ABCG2-Expressing Breast Cancer Cells, from Thermophilic Aspergillus terreus Liao, Wen-Ying; Shen, Chia-Ning; Lin, Li-Hua; Yang, Yu-Liang; Han, Hsin-Ying; Chen, Jing-Wei; Kuo, Sheng-Chu; Wu, Shih-Hsiung; Liaw, Chih-Chuang
國立臺灣大學 2011 Np-313, 2-Acetylamino-3-Chloro-1,4-Naphthoquinone, a Novel Antithrombotic Agent with Dual Inhibition of Thromboxane A2 Synthesis and Calcium Entry 郭姮蘭; 連金城; 張倩馨; 鍾鏡湖; 郭盛助; 許竣傑; 彭惠琴; 黃德富; KUO, HENG-LAN; LIEN, JIN-CHERNG; CHANG, CHIEN-HSIN; CHUNG, CHING-HU; KUO, SHENG-CHU; HSU, CHUN-CHIEH; PENG, HUI-CHIN; HUANG, TUR-FU
亞洲大學 2010-08 MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells 楊家欣;Yang, Jai-Sing;侯曼貞;Hour, Mann-Jen;黃雯雯;Huang, Wen-Wen;Lin, Kuei-Li;Kuo, Sheng-Chu;鍾景光;Chung, Jing-Gung
亞洲大學 2009-12 Novel quinolone CHM-1 induces apoptosis and inhibits metastasis in a human osterogenic sarcoma cell line 徐素琴;Hsu, Shu-Chun;楊家欣;Yang, Jai-Sing;郭昭麟;Kuo, Chao-Lin;羅琦;Lo, Chyi;林景彬;Lin, Jing-Pin;夏德椿;Hsia, Te-Chun;Lin, Jen-Jyh;Lai, Kuang-Chi;郭秀滿;Kuo, Hsiu-Maan;Huang, Li-Jiau;郭盛助;Kuo, Sheng-Chu;Wood, W.Gibson;鍾景光;Chung, Jing-Gung
國立成功大學 2009-06-15 Neuroprotective effects of furopyrazole derivative of benzylindazole analogs on C2 ceramide-induced apoptosis in cultured cortical neurons Lin, Yi-Chien; Chou, Li-Chen; Chen, Sheng-Chih; Kuo, Sheng-Chu; Huang, Li-Jiau; Gean, Po-Wu
國立成功大學 2009-05 Neuroprotective Effects of Ugonin K on Hydrogen Peroxide-Induced Cell Death in Human Neuroblastoma SH-SY5Y Cells Lin, Yi-Chien; Huang, Yaun-Chao; Chen, Sheng-Chih; Liaw, Chih-Chuang; Kuo, Sheng-Chu; Huang, Li-Jiau; Gean, Po-Wu
國立成功大學 2008-12-15 Investigation of amination in 4-chloro-2-phenylquinoline derivatives with amide solvents Tsai, Jui-Ying; Chang, Chih-Shiang; Huang, Yi-Fan; Chen, Hua-Shin; Lin, Shao-Kai; Wong, Fung Fuh; Huang, Li-Jiau; Kuo, Sheng-Chu
中山醫學大學 2008-11-11 4-Fluoro-N-butylphenylacetamide (H6) inhibits cell growth via cell-cycle arrest and apoptosis in human cervical cancer cells Liu, Chung-Hsien; Huang, Li-Jiau; Kuo, Sheng-Chu; Lee, Tsung-Hsien; Tsai, Kan-Jen; Chan, Hsu-Chin
衛生福利部國家中醫藥研究所 2008 4-(3;4-Dihydroxybenzoyloxymethyl) phenyl-O-β-D-glucopyranoside; an Antioxidant Isolated from Origanum vulgare Lin, Shiuan-Pey; Tsai, Shang-Yuan; Lin, Yun-Lian; Kuo, Sheng-Chu; Hou, Yu-Chi; Chao, Pei-Dawn Lee
國立臺灣大學 2008 Geraniin-Mediated Apoptosis by Cleavage of Focal Adhesion Kinase through up-Regulation of Fas Ligand Expression in Human Melanoma Cells 高銘欽; 黃麗嬌; 郭盛助; 林仁混; 魏宗德; KAO, MING-CHING; HUANG, LI-JIAU; KUO, SHENG-CHU; LIN, JEN-KUN; WAY, TZONG-DER
國立臺灣大學 2007 2-(3-Fluorophenyl)-6-Methoxyl-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid (Yjc-1) Induces Mitotic Phase Arrest in A549 Cells 郭盛助; 鍾景光; 賴雅韻; 鄧哲明; 潘秀玲; 黃麗嬌; KUO, SHENG-CHU; CHUNG, JING-GUNG; LAI, YA-YUN; TENG, CHE-MING; PAN, SHIOW-LIN; HUANG, LI-JIAU
國立臺灣大學 2007 Chm-1, a Novel Synthetic Quinolone with Potent 2776 and Selective Antitumor Activity against Human Hepatocellular Carcinoma 王士維; 郭盛助; 李國雄; 鄧哲明; WANG, SHIH-WEI; KUO, SHENG-CHU; LEE, KUO- HSIUNG; TENG, CHE-MING
國立臺灣大學 2007 Proteomic Approach to Studying the Cytotoxicity of Yca on U937 Leukemia Cells and Antileukernia Activity in Orthotopic Model of Leukemia Mice 鍾景光; 楊家欣; 黃麗嬌; 李芳郁; 鄧哲明; 蔡勝忠; 林奎利; 郭盛助; CHUNG, JING-GUNG; YANG, JAI-SING; HUANG, LI-JIAU; LEE, FANG-YU; TENG, CHE-MING; TSAI, SHENG-CHUNG; LIN, KUEI-LI; KUO, SHENG-CHU
國立臺灣大學 2007 Microwave-Assisted Synthesis of N-2-Benzyl-3-(4-Ethoxycarbonylphenyl) Indazole Derivatives 黃麗嬌; 李芳郁; 鄧哲明; 郭盛助; HUANG, LI-JIAU; LEE, FANG-YU; TENG, CHE-MING; KUO, SHENG-CHU
國立臺灣大學 2007 Synthesis of Furopyrazole Analogs of 1-Benzyl-3-(5-Hydroxymethyl-2-Furyl) Indazole (Yc-1) as Novel Anti-Leukemia Agents 黃麗嬌; 楊家欣; 李芳郁; 鄧哲明; 郭盛助; HUANG, LI-JIAU; YANG, JAI-SING; LEE, FANG-YU; TENG, CHE-MING; KUO, SHENG-CHU
國立臺灣大學 2007 Chm-1 Inhibits Hepatocyte Growth Factor-Induced Invasion of Sk-Hep-1 Human Hepatocellular Carcinoma Cells by Suppressing Matrix Metalloproteinase-9 Expression 王士維; 潘秀玲; 彭婕妤; 張雅玲; 顧記華; 郭盛助; 李國雄; 鄧哲明; WANG, SHIH-WEI; PAN, SHIOW-LIN; PENG, CHIEH-YU; CHANG, YA-LING; GUH, JIH-HWA; KUO, SHENG-CHU; LEE, KUO-HSIUNG; TENG, CHE-MING
國立臺灣大學 2007 Yc-1 Attenuates Lps-Induced Proinflammatory Responses and Activation of Nuclear Factor-Kappa B in Microglia 盧大宇; 湯智昕; 劉鴻祺; 鄧哲明; 郭盛助; 李芳郁; 符文美; LU, DAH-YUU; TANG, CHIH-HSIN; LIOU, HONG-CHI; TENG, CHE-MING; KUO, SHENG-CHU; LEE, FANG-YU; FU, WEN-MEI
國立臺灣大學 2007 Quinolone Analogue Inhibits Tubulin Polymerization and Induces Apoptosis Via Cdk1-Involved Signaling Pathways 陳依呈; 潘秀玲; 鄧哲明; 郭盛助; 林宗平; 何藴芳; 黃煜珺; 顧記華; CHEN, YING-CHENG; PAN, SHIOW-LIN; TENG, CHE-MING; KUO, SHENG-CHU; LIN, TSUNG-PING; HO, YUNN-FANG; HUANG, YU-CHUN; GUH, JIH-HWA
國立臺灣大學 2007 Yc-1 Inhibits Hif-1 Expression in Prostate Cancer Cells: Contribution of Akt/Nf-Kappa B Signaling to Hif-1 Alpha Accumulation during Hypoxia 黃耀霆; 潘秀玲; 顧記華; 李芳郁; 郭盛助; 鄧哲明; HUANG, YAO-TING; PAN, SHIOW-LIN; GUH, JIH-HWA; LEE, FANG-YU; KUO, SHENG-CHU; TENG, CHE-MING
國立成功大學 2006-11-15 Neuroprotective effect of N-acetylcysteine on neuronal apoptosis induced by a synthetic gingerdione compound: Involvement of ERK and p38 phosphorylation Lin, Chia-Ho; Kuo, Sheng-Chu; Huang, Li-Jiau; Gean, Po-Wu
國立臺灣大學 2006-01 Multiple cellular electrophysiological effects of a novel antiarrhythmic furoquinoline derivative HA-7 [N-benzyl-7-methoxy-2,3,4,9-tetrahydrofuro[2,3-b]quinoline-3,4-dione] in guinea pig cardiac preparations. Chang, Gwo-Jyh; Su, Ming-Jai; Kuo, Sheng-Chu; Lin, Tsung-Ping; Lee, Ying-Shiung
國立臺灣大學 2006 Investigation of Anti-Tumor Mechanisms of K2154: Characterization of Tubulin Isotypes, Mitotic Arrest and Apoptotic Machinery 盧品璇; 孔繁璐; 郭盛助; 闕士傑; 顧記華; LU, PIN-HSUAN; KUNG, FAN-LU; KUO, SHENG-CHU; CHUEH, SHIH-CHIEH; GUH, JIH-HWA
國立臺灣大學 2006 YC-1 [3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl Indazole] Inhibits Neointima Formation in Balloon-Injured Rat Carotid through Suppression of Expressions and Activities of Matrix Metalloproteinases 2 and 9 Liu, Yi-Nan; Pan, Shiow-Lin; Peng, Chieh-Yu; Guh, Jih-Hwa; Huang, Dong-Ming; Chang, Ya-Ling; Lin, Chun-Hung; Pai, Hui-Chen; Kuo, Sheng-Chu; Lee, Fang-Yu; Teng, Che-Ming
國立臺灣大學 2006 Yc-1 3-(5'-Hydroxymethyl-2'-Furyl)-1-Benzyl Indazole Inhibits Neointima Formation in Balloon-Injured Rat Carotid through Suppression of Expressions and Activities of Matrix Metalloproteinases 2 and 9 潘秀玲; 彭婕妤; 顧記華; 黃車明; 張雅玲; 郭盛助; 李芳郁; 鄧哲明; PAN, SHIOW-LIN; PENG, CHIEH-YU; GUH, JIH- HWA; HUANG, DONG-MING; CHANG, YA-LING; KUO, SHENG-CHU; LEE, FANG-YU; TENG, CHE-MING
國立臺灣大學 2005 Yc-1 Suppresses Constitutive Nuclear Factor-Kappa B Activation and Induces Apoptosis in Human Prostate Cancer Cells 鄧哲明; 郭盛助; 李芳郁; 張雅玲; 顧記華; 潘秀玲; 黃耀霆; TENG, CHE-MING; KUO, SHENG-CHU; LEE, FANG-YU; CHANG, YA-LING; GUH, JIH-HWA; PAN, SHIOW-LIN; HUANG, YAO-TING
國立臺灣大學 2005 Yc-1 3-(5'-Hydroxymethyl-2'-Furyl)-1-Benzyl Indazole Inhibits Endothelial Cell Functions Induced by Angiogenic Factors in Vitro and Angiogenesis in Vivo Models 鄧哲明; 李芳郁; 郭盛助; 鄭逢吉; 張雅玲; 王士維; 彭婕妤; 顧記華; 潘秀玲; TENG, CHE-MING; LEE, FANG-YU; KUO, SHENG-CHU; CHENG, FONG-CHI; CHANG, YA-LING; WANG, SHIH-WEI; PENG, CHIEH-YU; GUH, JIH-HWA; PAN, SHIOW-LIN
國立臺灣大學 2005 Yc-1 3-(5'-Hydroxymethyl-2'-Furyl)-1-Benzyl Indazole Exhibits a Novel Antiproliferative Effect and Arrests the Cell Cycle in G0-G1 in Human Hepatocellular Carcinoma Cells 王士維; 潘秀玲; 顧記華; 陳惠玲; 黃東明; 張雅玲; 郭盛助; 李芳郁; 鄧哲明; WANG, SHIH-WEI; PAN, SHIOW-LIN; GUH, JIH- HWA; CHEN, HUI-LING; HUANG, DONG-MING; CHANG, YA-LING; KUO, SHENG-CHU; LEE, FANG-YU; TENG, CHE-MING
國立臺灣大學 2005 A Potential Role of Yc-1 on the Inhibition of Cytokine Release in Peripheral Blood Mononuclear Leukocytes and Endotoxemic Mouse Models 潘秀玲; 顧記華; 彭婕妤; 張雅玲; 鄭逢吉; 郭盛助; 李芳郁; 鄧哲明; PAN, SHIOW-LIN; GUH, JIH-HWA; PENG, CHIEH -YU; CHANG, YA-LING; CHENG, FONG-CHI; KUO, SHENG-CHU; LEE, FANG-YU; TENG, CHE-MING
國立臺灣大學 2005 Enhancement of learning behaviour by a potent nitric oxide-guanylate cyclase activator YC-1 Chien, Wei-Lin; Liang, Keng-Chen; Teng, Che-Ming; Kuo, Sheng-Chu; Lee, Fang-Yu; Fu, Wen-Mei
國立臺灣大學 2004 The Indazole Derivative Yd-3 Inhibits Thrombin-Induced Vascular Smooth Muscle Cell Proliferation and Attenuates Intimal Thickening after Balloon Injury 彭婕妤; 潘秀玲; 顧記華; 張雅玲; 郭盛助; 李芳郁; 鄧哲明; PENG, CHIEH-YU; PAN, SHIOW-LIN; GUH, JIH-HWA; CHANG, YA-LING; KUO, SHENG-CHU; LEE, FANG-YU; TENG, CHE-MING
國立臺灣大學 2004 The Inhibitory Mechanism of Yc-1, a Benzyl Indazole, on Smooth Muscle Cell Proliferation: An in Vitro and in Vivo Study 吳介信; 張文正; 郭盛助; 鄧哲明; WU, CHIEH-HSI; CHANG, WENG-CHENG; KUO, SHENG-CHU; TENG, CHE-MING
國立臺灣大學 2004 Yc-1 Prevents Sodium Nitroprusside-Mediated Apoptosis in Vascular Smooth Muscle Cells 潘秀玲; 顧記華; 張雅玲; 郭盛助; 李芳郁; 鄧哲明; PAN, SHIOW-LIN; GUH, JIH-HWA; CHANG, YA- LING; KUO, SHENG-CHU; LEE, FANG-YU; TENG, CHE-MING
國立臺灣大學 2003 Enhancement of Long-Term Potentiation by a Potent Nitric Oxide-Guanylyl Cyclase Activator, 3-(5-Hydroxymethyl-2-furyl)-1-benzyl-indazole Chien, Wei-Lin; Liang, Keng-Chen; Teng, Che-Ming; Kuo, Sheng-Chu; Lee, Fang-Yu; Fu, Wen-Mei
國立成功大學 2002-02 Marked decrease of cyclosporin absorption caused by phellamurin in rats Chen, Hung-Yi; Wu, Tian-Shung; Su, Sheng-Fang; Kuo, Sheng-Chu; Chao, Pei-Dawn Lee
國立臺灣大學 2002 Inhibition of Ras-Mediated Cell Proliferation by Benzyloxybenzaidehyde 潘秀玲; 顧記華; 張雅玲; 黃麗嬌; 郭盛助; 鄧哲明; PAN, SHIOW-LIN; GUH, JIH-HWA; CHANG, YA-LING; HUANG, LI-JIAU; KUO, SHENG-CHU; TENG, CHE-MING
國立臺灣大學 2002 Selective Inhibition of Protease-Activated Receptor 4-Dependent Platelet Activation by Yd-3 吳志中; 廖長輝; 郭盛助; 李芳郁; 李春燕; 鄧哲明; WU, CHIN-CHUNG; LIAO, CHANG-HUI; KUO, SHENG-CHU; LEE, FANG-YU; LEE, CHUN-YANN; TENG, CHE-MING
國立臺灣大學 2002 Synthesis and Biological Evaluation of Substituted Ethyl Furo 2,3-B Chromone-2-Carboxylates 張嘉麟; 吳錦生; 郭盛助; 王繼平; 鄧哲明; CHANG, CHIA-LIN; WU, CHIN-SHENG; KUO, SHENG-CHU; WANG, JIH-PYANG; TENG, CHE-MING
國立臺灣大學 2002 Synthesis and Anti-Platelet Activity of Ferulamide Derivatives 賴雅韻; 黃麗嬌; 林顯正; 吳天賞; 鄧哲明; 郭盛助; LAI, YA-YUN; HUANG, LI-JIAU; LIN, HSIEH-CHENG; WU, TIEN-SHUNG; TENG, CHE-MING; KUO, SHENG-CHU
國立臺灣大學 2002 Synthesis and Antiplatelet Activity of 9-Benzyl-3-Hydroxymethylcarbazoles 李春燕; 郭盛助; 鄧哲明; 黃麗嬌; LEE, CHUN-YANN; KUO, SHENG-CHU; TENG, CHE-MING; HUANG, LI-JIAU
國立成功大學 2001-09 Determination and disposition kinetics of phellamurin metabolites in rat brain Chen, Hung-Yi; Wu, Tian-Shung; Hou, Y. C.; Kuo, Sheng-Chu; Chao, Pei-Dawn Lee
國立成功大學 2001-08 Cytotoxicity of Ganoderma lucidum triterpenes Wu, Tian-Shung; Shi, Li-Shian; Kuo, Sheng-Chu
國立成功大學 2001-02 The fate of phellamurin in rats. Chen, Hung-Yi; Wu, Tian-Shung; Wang, Jih-Pyang; Kuo, Sheng-Chu; Lee Chao, Pei-Dawn
國立臺灣大學 2000 Electrophysiological Characteristics of Antiarrhythmic Potential of Acrophyllidin, a Furoquinoline Alkaloid Isolated From Acronychia halophylla 張國志; 吳美環; 陳文彬; 郭盛助; 蘇銘嘉; CHANG, GWO-JYH; WU, MEI-HWAN; CHEN, WEN- PIN; KUO, SHENG-CHU; SU, MING-JAI
國立臺灣大學 2000 Synthesis and Antiplatelet Activity of Alkoxy Derivatives of 2- Phenylquinazolines 侯曼貞; 黃麗嬌; 鄧哲明; 郭盛助; HOUR, MANN-JEN; HUANG, LI-JIAU; TENG, CHE -MING; KUO, SHENG-CHU

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