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Institution Date Title Author
國家衛生研究院 2024-11 DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration Lin, SY;Chang, YC;Tien, YW;Kuo, YH;Chang, HF;Ou, LC;Chen, YP;Chang, KH;Hsu, YT;Huang, YC;Yang, CM;Law, PY;Xi, JH;Tao, PL;Loh, HH;Yeh, TK;Zhuang, H;Hsieh, HP;Shih, C;Chen, CT;Yeh, SH;Ueng, SH
國家衛生研究院 2022-06-02 Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone Lin, SY;Tien, YW;Ke, YY;Chang, YC;Chang, HF;Ou, LC;Law, PY;Xi, JH;Tao, PL;Loh, HH;Chao, YS;Shih, C;Chen, CT;Yeh, SH;Ueng, SH
國家衛生研究院 2019-06-05 Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice Yang, PP;Yeh, TK;Loh, HH;Law, PY;Wang, Y;Tao, PL
國家衛生研究院 2019-04-01 The in vivo antinociceptive and mu-opioid receptor activating effects of the combination of N-phenyl-2′,4′-dimethyl-4,5′-bi-1,3-thiazol-2-amines and naloxone Lin, SY;Kuo, YH;Tien, YW;Ke, YY;Chang, WT;Chang, HF;Ou, LC;Law, PY;Xi, JH;Tao, PL;Loh, HH;Chao, YS;Shih, C;Chen, CT;Yeh, SH;Ueng, SH
國家衛生研究院 2019-02-20 Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice Chao, PK;Chang, HF;Ou, LC;Chuang, JY;Lee, PT;Chang, WT;Chen, SC;Ueng, SH;Hsu, JT;Tao, PL;Law, PY;Loh, HH;Yeh, SH
國家衛生研究院 2017-05 1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A novel opioid receptor agonist with less accompanying gastrointestinal dysfunction than morphine Chao, PK;Ueng, SH;Ou, LC;Yeh, TK;Chang, WT;Chang, HF;Chen, SC;Tao, PL;Law, PY;Loh, HH;Cheng, MF;Chuang, JY;Chen, CT;Shih, C;Yeh, SH
國家衛生研究院 2017-01 Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists Chen, SR;Ke, YY;Yeh, TK;Lin, SY;Ou, LC;Chen, SC;Chang, WT;Chang, HF;Wu, ZH;Hsieh, CC;Law, PY;Loh, HH;Shih, C;Lai, YK;Yeh, SH;Ueng, SH
國家衛生研究院 2016-09 Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice Yang, PP;Yeh, GC;Yeh, TK;Xi, J;Loh, HH;Law, PY;Tao, PL
國家衛生研究院 2015-09-22 Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice Yang, PP;Yeh, GC;Huang, EY;Law, PY;Loh, HH;Tao, PL
國家衛生研究院 2015-01 Effect of naltrexone on neuropathic pain in mice locally transfected with the mutant mu-opioid receptor gene in spinal cord Kao, JH;Gao, MJ;Yang, PP;Law, PY;Loh, HH;Tao, PL
國家衛生研究院 2014-12-01 Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling Lee, PT;Chao, PK;Ou, LC;Chuang, JY;Lin, YC;Chen, SC;Chang, HF;Law, PY;Loh, HH;Chao, YS;Su, TP;Yeh, SH
國家衛生研究院 2014-09 Discovery, structure-activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists Cheng, MF;Ou, LC;Chen, SC;Chang, WT;Law, PY;Loh, HH;Chao, YS;Shih, C;Yeh, SH;Ueng, SH
國家衛生研究院 2014-06 Treatment of skin cancer pain with naltrexone in mice locally transfected with a mutant mu-opioid receptor gene in spinal cord Tao, PL;Kung, WH;Kao, JH;Yang, PP;Law, PY;Loh, HH
國家衛生研究院 2012-08 Naloxone can act as an analgesic agent without measurable chronic side effects in mice with a mutant mu-opioid receptor expressed in different sites of pain pathway Chou, SH;Kao, JH;Tao, PL;Law, PY;Loh, HH
國家衛生研究院 2011-09 S151 the central antinociceptive effect of oxycodone can be mediated via non-opioid receptor mechanism Tao, PL;Yang, PP;Yeh, GC;Law, PY;Loh, HH

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