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机构 日期 题名 作者
國立臺灣大學 2006 Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies Tsai, Keng-Chang; Chen, Shih-Yuan; Liang, Po-Huang; Lu, I-Lin; Mahindroo, Neeraj; Hsieh, Hsing-Pang; Chao, Yu-Sheng; Liu, Lincoln; Liu, Donald; Lien, Wei; Lin, Thy-Hou; Wu, Su-Ying
國立臺灣大學 2006 An E. coli lon mutant conferring partial resistance to colicin may reveal a novel role in regulating proteins involved in the translocation of colicin Lee, Yuan-Yu; Hu, Hsiao-Tin; Liang, Po-Huang; Chak, Kin-Fu
國立臺灣大學 2006 Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Main Protease Lu, I-Lin; Mahindroo, Neeraj; Liang, Po-Huang; Peng, Yi-Hui; Kuo, Chih-Jung; Tsai, Keng-Chang; Hsieh, Hsing-Pang; Chao, Yu-Sheng; Wu, Su-Ying
國立臺灣大學 2006 Pharmacophores and biological activities of severe acute respiratory syndrome viral protease inhibitors Wang, Hui-Min; Liang, Po-Huang
臺大學術典藏 2006 Stable Benzotriazole Esters as Mechanism-Based Inactivators of the Severe Acute Respiratory Syndrome 3CL Protease Shie, Jiun-Jie; Ho, Ming-Yi; Liao, Chung-Lin; Wu, Ying-Ta; Fang, Jim-Min; Kuo, Chih-Jung; King, Ke-Yung; Wu, Chung-Yi; Wu, Chung-Yi; King, Ke-Yung; Kuo, Chih-Jung; Fang, Jim-Min; Wu, Ying-Ta; Ho, Ming-Yi; Liao, Chung-Lin; Shie, Jiun-Jie; Liang, Po-Huang; Wong, Chi-Huey; Liang, Po-Huang; Wong, Chi-Huey
臺大學術典藏 2006 Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies Tsai, Keng-Chang; Chen, Shih-Yuan; Liang, Po-Huang; Lu, I-Lin; Mahindroo, Neeraj; Hsieh, Hsing-Pang; Chao, Yu-Sheng; Liu, Lincoln; Liu, Donald; Lien, Wei; Lin, Thy-Hou; Wu, Su-Ying; Tsai, Keng-Chang; Chen, Shih-Yuan et al.
國立臺灣大學 2005 Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic α,β-unsaturated esters Shie, Jiun-Jie; Fang, Jim-Min; Kuo, Tun-Hsun; Kuo, Chih-Jung; Liang, Po-Huang; Huang, Hung-Jyun; Wu, Yin-Ta; Jan, Jia-Tsrong; Cheng, Yih-Shyun E.; Wong, Chi-Huey
國立臺灣大學 2005 Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease Shie, Jiun-Jie; Fang, Jim-Min; Kuo, Chih-Jung; Kuo, Tun-Hsun; Liang, Po-Huang; Huang, Hung-Jyun; Yang, Wen-Bin; Lin, Chun-Hung; Chen, Jiun-Ling; Wu, Yin-Ta; Wong, Chi-Huey
國立臺灣大學 2005 Mechanism of the Maturation Process of SARS-CoV 3CL Protease Hsu, Min-Feng; Kuo, Chih-Jung; Chang, Kai-Ti; Chang, Hui-Chuan; Chou, Chia-Cheng; Ko, Tzu-Ping; Shr, Hui-Lin; Chang, Gu-Gang; Wang, Andrew H.-J.; Liang, Po-Huang
國立臺灣大學 2005 Crystal Structures of Undecaprenyl Pyrophosphate Synthase in Complex with Magnesium, Isopentenyl Pyrophosphate, and Farnesyl Thiopyrophosphate-ROLES OF THE METAL ION AND CONSERVED RESIDUES IN CATALYSIS Guo, Rey-Ting; Ko, Tzu-Ping; Chen, Annie P.-C.; Kuo, Chih-Jung; Wang, Andrew H.-J.; Liang, Po-Huang
國立臺灣大學 2005 Homodimeric Hexaprenyl Pyrophosphate Synthase from the Thermoacidophilic Crenarchaeon Sulfolobus solfataricus Displays Asymmetric Subunit Structures Sun, Han-Yu; Ko, Tzu-Ping; Kuo, Chih-Jung; Guo, Rey-Ting; Chou, Chia-Cheng; Liang, Po-Huang; Wang, Andrew H.-J.
國立臺灣大學 2005 Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase Chen, Annie P.-C.; Chang, Sing-Yang; Lin, Yu-Chung; Sun, Yang-Sheng; Chen, Chao-Tsen; Wang, Andrew H.-J.; Liang, Po-Huang
臺大學術典藏 2005 Mechanism of the Maturation Process of SARS-CoV 3CL Protease Kuo, Chih-Jung; Chang, Kai-Ti; Chang, Hui-Chuan; Chou, Chia-Cheng; Ko, Tzu-Ping; Shr, Hui-Lin; Chang, Gu-Gang; Wang, Andrew H.-J.; Liang, Po-Huang; Hsu, Min-Feng; Hsu, Min-Feng; Kuo, Chih-Jung; Chang, Kai-Ti; Chang, Hui-Chuan; Chou, Chia-Cheng; Ko, Tzu-Ping; Shr, Hui-Lin; Chang, Gu-Gang; Wang, Andrew H.-J.; Liang, Po-Huang
國立臺灣大學 2004 Small molecules targeting severe acute respiratory syndrome human coronavirus Wu, Chung-Yi; Jan, Jia-Tsrong; Ma, Shiou-Hwa; Kuo, Chih-Jung; Juan, Hsueh-Fen; Cheng, Yih-Shyun E.; Hsu, Hsien-Hua; Huang, Hsuan-Cheng; Wu, Douglass; Brik, Ashraf; Liang, Fu-Sen; Liu, Rai-Shung; Fang, Jim-Min; Chen, Shui-Tein; Liang, Po-Huang; Wong, Chi-Huey
國立臺灣大學 2004 Crystal Structure of Octaprenyl Pyrophosphate Synthase from Hyperthermophilic Thermotoga maritima and Mechanism of Product Chain Length Determination Guo, Rey-Ting; Kuo, Chih-Jung; Chou, Chia-Cheng; Ko, Tzu-Ping; Shr, Hui-Lin; Liang, Po-Huang; Wang, Andrew H.-J.
國立臺灣大學 2004 Substrate binding mode and reaction mechanism of undecaprenyl pyrophosphate synthase deduced from crystallographic studies Chang, Sing-Yang; Ko, Tzu-Ping; Chen, Annie P.-C.; Wang, Andrew H.-J.; Liang, Po-Huang
國立臺灣大學 2004 A Molecular Ruler for Chain Elongation Catalyzed by Octaprenyl Pyrophosphate Synthase and Its Structure-Based Engineering To Produce Unprecedented Long Chain trans-Prenyl Products Guo, Rey-Ting; Kuo, Chih-Jung; Ko, Tzu-Ping; Chou, Chia-Cheng; Liang, Po-Huang; Wang, Andrew H.-J.
國立臺灣大學 2003 Preliminary X-ray diffraction analysis of octaprenyl pyrophosphate synthase crystals from Thermotoga maritima and Escherichia coli Guo, Rey-Ting; Ko, Tzu-Ping; Chou, Chia-Cheng; Shr, Hui-Lin; Chu, Hsing-Mao; Tsai, Yao-Hsien; Liang, Po-Huang; Wan, Andrew H.-J.
國立臺灣大學 2002 Insight into the activation mechanism of Escherichia coli octaprenyl pyrophosphate synthase derived from pre-steady-state kinetic analysis Pan, Jian-Jung; Kuo, Tun-Hsun; Chen, Yi-Kai; Yang, Lee-Wei; Liang, Po-Huang
國立臺灣大學 2002 Reaction kinetic pathway of the recombinant octaprenyl pyrophosphate synthase from Thermotoga maritima: how is it different from that of the mesophilic enzyme Kuo, Tun-Hsun; Liang, Po-Huang
國立臺灣大學 2002 Synthesis and Application of A Fluorescent Substrate Analogue to Study Ligand Interactions for Undecaprenyl Pyrophosphate Synthase Chen, Annie P.-C.; Chen, Yi-Hung; Liu, Hsiao-Pei; Li, Yu-Chin; Chen, Chao-Tsen; Liang, Po-Huang
國立臺灣大學 2002 Probing the Conformational Change of Escherichia coli Undecaprenyl Pyrophosphate Synthase during Catalysis Using an Inhibitor and Tryptophan Mutants Chen, Yi-Hung; Chen, Annie P.-C.; Chen, Chao-Tsen; Wang, Andrew H.-J.; Liang, Po-Huang
臺大學術典藏 2002 Synthesis and Application of A Fluorescent Substrate Analogue to Study Ligand Interactions for Undecaprenyl Pyrophosphate Synthase Chen, Annie P.-C.; Chen, Yi-Hung; Liu, Hsiao-Pei; Li, Yu-Chin; Chen, Chao-Tsen; Liang, Po-Huang; Chen, Annie P.-C.; Chen, Yi-Hung; Liu, Hsiao-Pei; Li, Yu-Chin; Chen, Chao-Tsen; Liang, Po-Huang
臺大學術典藏 2002 Probing the Conformational Change of Escherichia coli Undecaprenyl Pyrophosphate Synthase during Catalysis Using an Inhibitor and Tryptophan Mutants Chen, Yi-Hung; Chen, Annie P.-C.; Chen, Chao-Tsen; Wang, Andrew H.-J.; Liang, Po-Huang; Chen, Yi-Hung; Chen, Annie P.-C.; Chen, Chao-Tsen; Wang, Andrew H.-J.; Liang, Po-Huang
國立臺灣大學 2001 Mechanism of Product Chain Length Determination and the Role of a Flexible Loop in Escherichia coli Undecaprenyl-pyrophosphate Synthase Catalysis Ko, Tzu-Ping; Chen, Yi-Kai; Robinson, Howard; Tsai, Pei-Chun; Gao, Yi-Gui; Chen, Annie P.-C.; Wang, Andrew H.-J.; Liang, Po-Huang

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