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臺灣學術機構典藏系統 (Taiwan Academic Institutional Repository, TAIR)
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Institution Date Title Author
國家衛生研究院 2023-02-07 Development of furanopyrimidine-based orally active third- generation EGFR inhibitors for the treatment of non-small cell lung cancer Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2022-02-07 Development of furanopyrimidine-based orally active third-generation EGFR inhibitors for the treatment of non-small cell lung cancer Li, MC;Coumar, MS;Lin, SY;Lin, YS;Huang, GL;Chen, CH;Lien, TW;Wu, YW;Chen, YT;Chen, CP;Huang, YC;Yeh, KC;Yang, CM;Kalita, B;Pan, SL;Hsu, TA;Yeh, TK;Chen, CT;Hsieh, HP
國家衛生研究院 2019-09-27 Discovery of a furanopyrimidine-based epidermal growth factor receptor inhibitor (DBPR112) as a clinical candidate for the treatment of non-small cell lung cancer Lin, SY;Chang Hsu, Y;Peng, YH;Ke, YY;Lin, WH;Sun, HY;Shiao, HY;Kuo, FM;Chen, PY;Lien, TW;Chen, CH;Chu, CY;Wang, SY;Yeh, KC;Chen, CP;Hsu, TA;Wu, SY;Yeh, TK;Chen, CT;Hsieh, HP
國立交通大學 2014-12-08T15:18:14Z Inhibition of hepatitis C virus replication by antimonial compounds Hwang, DR; Lin, RK; Leu, GZ; Lin, TY; Lien, TW; Yu, MC; Yeh, CT; Hsu, JTA
國家衛生研究院 2012-02 Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents Li, WT;Hwang, DR;Song, JS;Chen, CP;Chen, TW;Lin, CH;Chuu, JJ;Lien, TW;Hsu, TA;Huang, CL;Tseng, HY;Lin, CC;Lin, HL;Chang, CM;Chao, YS;Chen, CT
國家衛生研究院 2012-01 A High-throughput cell-based screening for L858R/T790M mutant epidermal growth factor receptor inhibitors Lin, WH;Song, JS;Lien, TW;Chang, CY;Wu, SH;Huang, YW;Chang, TY;Fang, MY;Yen, KJ;Chen, CH;Chu, CY;Hsieh, HP;Chen, YR;Chao, YS;Hsu, JT
國家衛生研究院 2011-08 BPR1K653, a novel aurora kinase inhibitor, exhibits potent anti-proliferative activity in MDR1 (P-gp170)-mediated multidrug-resistant cancer cells Cheung, CH;Lin, WH;Hsu, TA;Hour, TC;Yeh, TK;Ko, S;Lien, TW;Coumar, MS;Liu, JF;Lai, WY;Shiao, HY;Lee, TR;Hsieh, HP;Chang, JY
國家衛生研究院 2011-06-01 Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells Chiu, HC;Chou, DL;Huang, CT;Lin, WH;Lien, TW;Yen, KJ;Hsu, JT
國家衛生研究院 2010-10-28 Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and michael acceptor group for maximal potency Wu, CH;Coumar, MS;Chu, CY;Lin, WH;Chen, YR;Chen, CT;Shiao, HY;Rafi, S;Wang, SY;Hsu, H;Chen, CH;Chang, CY;Chang, TY;Lien, TW;Fang, MY;Yeh, KC;Chen, CP;Yeh, TK;Hsieh, SH;Hsu, JT;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院 2010-10 Structural basis for the improved potency of peroxisome proliferator-activated receptor (PPAR) agonists Peng, YH;Coumar, MS;Leou, JS;Wu, JS;Shiao, HY;Lin, CH;Lin, WH;Lien, TW;Chen, X;Hsu, JT;Chao, YS;Huang, CF;Lyu, PC;Hsieh, HP;Wu, SY
國家衛生研究院 2010-06-15 Fast-forwarding hit to lead: Aurora and epidermal growth factor receptor kinase inhibitor lead identification Coumar, MS;Chu, CY;Lin, CW;Shiao, HY;Ho, YL;Reddy, R;Lin, WH;Chen, CH;Peng, YH;Leou, JS;Lien, TW;Huang, CT;Fang, MY;Wu, SH;Wu, JS;Chittimalla, SK;Song, JS;Hsu, JT;Wu, SY;Liao, CC;Chao, YS;Hsieh, HP
國家衛生研究院 2009-04-23 Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists Lin, CH;Peng, YH;Coumar, MS;Chittimalla, SK;Liao, CC;Lyn, PC;Huang, CC;Lien, TW;Lin, WH;Hsu, JT;Cheng, JH;Chen, X;Wu, JS;Chao, YS;Lee, HJ;Juo, CG;Wu, SY;Hsieh, HP
國家衛生研究院 2009-02-26 Structure-based drug design of novel aurora kinase a inhibitors: Structural basis for potency and specificity Coumar, MS;Leou, JS;Shukla, P;Wu, JS;Dixit, AK;Lin, WH;Chang, CY;Lien, TW;Tan, UK;Chen, CH;Hsu, JTA;Chao, YS;Wu, SY;Hsieh, HP
國家衛生研究院 2008-06-01 A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors Lin, WH; Song, JS; Chang, TY; Chang, CY; Fu, YN; Yeh, CL; Wu, SH; Huang, YW; Fang, MY; Lien, TW; Hsieh, HP; Chao, YS; Huang, SF; Tsai, SF; Wang, LM; Hsu, JTA; Chen, YR
國家衛生研究院 2008-05 Bioassay-guided purification and identification of PPARa/gamma agonists from Chlorella sorokiniana Chou, YC; Prakash, E; Huang, CF; Lien, TW; Chen, X; Su, IJ; Chao, YS; Hsieh, HP; Hsu, JTA
國家衛生研究院 2006-10-19 Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists Mahindroo, N; Peng, YH; Lin, CH; Tan, UK; Prakash, E; Lien, TW; Lu, IL; Lee, HJ; Hsu, JTA; Chen, X; Liao, CC; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-05-04 Structure-based drug design of a novel family of PPAR gamma partial agonists: Virtual screening, X-ray crystallography, and in vitro/in vivo biological activities Lu, IL; Huang, CF; Peng, YH; Lin, YT; Hsieh, HP; Chen, CT; Lien, TW; Lee, HJ; Mahindroo, N; Prakash, E; Yueh, A; Chen, HY; Goparaju, CMV; Chen, X; Liao, CC; Chao, YS; Hsu, JTA; Wu, SY
國家衛生研究院 2006-02-09 Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies Mahindroo, N; Wang, CC; Liao, CC; Huang, CF; Lu, IL; Lien, TW; Peng, YH; Huang, WJ; Lin, YT; Hsu, MC; Lin, CH; Tsai, CH; Hsu, JTA; Chen, X; Lyu, PC; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2006-01-01 Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system Hwang, DR;Wu, YS;Chang, CW;Lien, TW;Chen, WC;Tan, UK;Hsu, JTA;Hsieh, HP
國家衛生研究院 2005-12-29 Novel indole-based peroxisome proliferator-activated receptor agonists: Design, SAR, structural biology, and biological activities Mahindroo, N; Huang, CF; Peng, YH; Wang, CC; Liao, CC; Lien, TW; Chittimalla, SK; Huang, WJ; Chai, CH; Prakash, E; Chen, CP; Hsu, TA; Peng, CH; Lu, IL; Lee, LH; Chang, YW; Chen, WC; Chou, YC; Chen, CT; Goparaju, CMV; Chen, YS; Lan, SJ; Yu, MC; Chen, X; Chao, YS; Wu, SY; Hsieh, HP
國家衛生研究院 2005-10 Inhibition of hepatitis C virus replication by antimonial compounds Hwang, DR; Lin, RK; Leu, GZ; Lin, TY; Lien, TW; Yu, MC; Yeh, CT; Hsu, JTA
國家衛生研究院 2005-08 High-throughput cell-based screening for hepatitis C virus NS3/4A protease inhibitors Lee, JC; Yu, MC; Lien, TW; Chang, CF; Hsu, JTA
國家衛生研究院 2005-03 Design, synthesis and sar of indole-based PPAR agonists Hsieh, HP;Mahindroo, N;Coumar, MS;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Lin, YT;Lee, LH;Prakash, E;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Chao, YS
國家衛生研究院 2005-03 Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents Hsieh, HP;Mahindroo, N;Wang, CC;Huang, CF;Lien, TW;Tsai, CH;Peng, YH;Lee, LH;Prakash, E;Chen, WC;Chang, YW;Hsu, TA;Chen, X;Wu, SY;Chen, CT;Lan, SJ;Chao, YS
國立臺灣大學 2003-04 Haemolymph parameters of Pacific white shrimp (Litopenaeus vannamei) infected with Taura syndrome virus. Song, YL; Yu, CI; Lien, TW; Huang, CC; Lin, MN
國立臺灣大學 2002-06 Genomic similarity of Taura syndrome virus (TSV) between Taiwan and Western hemisphere isolates. Lien, TW; Hsiung, HC; Huang, CC; Song, YL

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