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Institution Date Title Author
臺大學術典藏 2021-07-07T05:13:17Z Synthesis and Opioid Activity of 7-Oxygenated 2,3,4,4a,5,6,7,7a-octahydro-1H-benzofuro[3,2-e]isoquinolin-9-ols Cheng C.-Y.; LING-WEI HSIN; Tsai M.-C.; Schmidt W.K.; Smith C.; Tam S.W.
臺大學術典藏 2021-07-07T05:13:17Z Selective Reversible and Irreversible Ligands for the k Opioid Receptor Cheng C.-Y.; Shou-Chien W.; LING-WEI HSIN; Tam S.W.
臺大學術典藏 2021-07-07T05:13:16Z Synthesis of 1,4-bis [(17-normorphinyl)methyl]cubane, a morphine dimer linked by cubane Cheng C.-Y.; LING-WEI HSIN; Tao P.-L.
臺大學術典藏 2021-07-07T05:13:16Z N-Cubylmethyl substituted morphinoids as novel narcotic antagonists Cheng C.-Y.; LING-WEI HSIN; Lin Y.-P.; Tao P.-L.; Jong T.-T.
臺大學術典藏 2021-07-07T05:13:16Z Novel radical synthesis of morphine fragments spiro[benzofuran-3(2H),4'-piperidine] and octahydro-1H-benzofuro[3,2-e]isoquinoline Cheng C.-Y.; LING-WEI HSIN; Liou J.-P.
臺大學術典藏 2021-07-07T05:13:15Z Synthesis and biological activity of fluoro-substituted pyrrolo[2,3-d]pyrimidines: The development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor LING-WEI HSIN; Webster E.L.; Chrousos G.P.; Gold P.W.; Eckelman W.C.; Contoreggi C.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:15Z Synthesis of [3H](4-fluorobutyl)propyl[2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-yl]amine: A potent radioligand for corticotropin-releasing hormone type 1 receptor LING-WEI HSIN; Webster E.L.; Chrousos G.P.; Gold P.W.; Eckelman W.C.; Contoreggi C.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:15Z Oxygenated analogues of 1-[2-(diphenylmethoxy)ethyl]- and 1- [2- [bis (4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents Lewis D.B.; Matecka D.; Zhang Y.; LING-WEI HSIN; Dersch C.M.; Stafford D.; Glowa J.R.; Rothman R.B.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:14Z Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: Chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy) ethyl]-4-(3-phenylpropyl)piperazine LING-WEI HSIN; Dersch C.M.; Baumann M.H.; Stafford D.; Glowa J.R.; Rothman R.B.; Jacobson A.E.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:14Z The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type 1 Tian X.; LING-WEI HSIN; Webster E.L.; Contoreggi C.; Chrousos G.P.; Gold P.W.; Habib K.; Ayala A.; Eckelman W.C.; Jacobson A.E.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:14Z Synthesis of 1,4-dihydro-2-phenyl-4,4-bis(4-pyridinylmethyl)-2H-isoquinolin-3-one and related compounds as acetylcholine release enhancers Lin M.-S.; LING-WEI HSIN; Tsai H.-B.; Tsai M.-C.; Cheng C.-Y.
臺大學術典藏 2021-07-07T05:13:14Z CRHR1Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists LING-WEI HSIN; Tian X.; Webster E.L.; Coop A.; Caldwell T.M.; Jacobson A.E.; Chrousos G.P.; Gold P.W.; Habib K.E.; Ayala A.; Eckelman W.C.; Contoreggi C.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:13Z Synthesis and dopamine transporter affinity of chiral 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(2-hydroxypropyl)piperazines as potential cocaine abuse therapeutic agents LING-WEI HSIN; Prisinzano T.; Wilkerson C.R.; Dersch C.M.; Horel R.; Jacobson A.E.; Rothman R.B.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:13Z N-Arylated pyrrolidin-2-ones and morpholin-3-ones as potassium channel openers Liang P.-H.; LING-WEI HSIN; Cheng C.-Y.
臺大學術典藏 2021-07-07T05:13:13Z Synthesis of galanthamine analogs as acetylcholinesterase inhibitors via intramolecular heck cvclization Liang P.-H.; LING-WEI HSIN; Pong S.-L.; Hsu C.-H.; Cheng C.-Y.
臺大學術典藏 2021-07-07T05:13:12Z Asymmetric total synthesis of (-)-octahydro-1H-benzofuro[3,2-e] isoquinoline, a partial structure of morphine LING-WEI HSIN; Chen C.-W.; Chang L.-T.
臺大學術典藏 2021-07-07T05:13:12Z Synthesis of 3-[4-acyl-2-(1-methoxy-1-methylethyl)morpholin-3-yl]- benzonitriles as novel potassium channel openers Lin M.-S.; LING-WEI HSIN; Cheng C.-Y.
臺大學術典藏 2021-07-07T05:13:12Z Intramolecular Heck cyclization to the galanthamine-type alkaloids: Total synthesis of (±)-lycoramine Liang P.-H.; Liu J.-P.; LING-WEI HSIN; Cheng C.-Y.
臺大學術典藏 2021-07-07T05:13:12Z A concise synthesis of (S)-(+)-1-(4-{2-[bis-(4-fluorophenyl)methoxy]-ethyl} piperazin-1-yl)-2-phenylpropan-2-ol dimaleate Prisinzano T.; LING-WEI HSIN; Folk J.E.; Flippen-Anderson J.L.; George C.; Jacobson A.E.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:11Z The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats Jutkiewicz E.M.; Wood S.K.; Houshyar H.; LING-WEI HSIN; Rice K.C.; Woods J.H.
臺大學術典藏 2021-07-07T05:13:11Z Stereoselective synthesis of morphine fragments trans- and cis-octahydro-1H-benzo[4,5]furo[3,2-e]isoquinolines LING-WEI HSIN; Chang L.-T.; Chen C.-W.; Hsu C.-H.; Chen H.-W.
臺大學術典藏 2021-07-07T05:13:10Z Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: Role of amino, fluoro, hydroxyl, methoxyl, methyl, methylene, and oxo substituents on affinity for the dopamine and serotonin transporters LING-WEI HSIN; Chang L.-T.; Rothman R.B.; Dersch C.M.; Jacobson A.E.; Rice K.C.
臺大學術典藏 2021-07-07T05:13:10Z WRC-213, an l-methionine-conjugated mitoxantrone derivative, displays anticancer activity with reduced cardiotoxicity and drug resistance: Identification of topoisomerase II inhibition and apoptotic machinery in prostate cancers Hsiao C.-J.; Li T.-K.; Chan Y.-L.; LING-WEI HSIN; Liao C.-H.; Lee C.-H.; Lyu P.-C.; Guh J.-H.
臺大學術典藏 2021-07-07T05:13:10Z Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates LING-WEI HSIN; Wang H.-P.; Kao P.-H.; Lee O.; Chen W.-R.; Chen H.-W.; Guh J.-H.; Chan Y.-L.; His C.-P.; Yang M.-S.; Li T.-K.; Lee C.-H.
臺大學術典藏 2021-07-07T05:13:09Z A practical asymmetric synthesis of the ACNO fragment of morphine alkaloids LING-WEI HSIN; Chang L.-T.; Liou H.-L.
臺大學術典藏 2021-07-07T05:13:09Z Identification of a novel "almost neutral" μ-opioid receptor antagonist in CHO cells expressing the cloned human μ-opioid receptor Sally E.J.; Xu H.; Dersch C.M.; LING-WEI HSIN; Chang L.-T.; Prisinzano T.E.; Simpson D.S.; Giuvelis D.; Rice K.C.; Jacobson A.E.; Cheng K.; Bilsky E.J.; Rothman R.B.
臺大學術典藏 2021-07-07T05:13:09Z Synthesis and opioid activity of enantiomeric N-substituted 2,3,4,4a,5,6,7, 7a-octahydro-1H-benzofuro[3,2-e]isoquinolines LING-WEI HSIN; Chang L.-T.; Rothman R.B.; Dersch C.M.; Fishback J.A.; Matsumoto R.R.
臺大學術典藏 2021-07-07T05:13:08Z Anthracenedione-methionine conjugates are novel topoisomerase II-targeting anticancer agents with favorable drug resistance profiles Lee C.-H.; Hsieh M.-Y.; LING-WEI HSIN; Chen H.-C.; Lo S.-C.; Fan J.-R.; Chen W.-R.; Chen H.-W.; Chan N.-L.; Li T.-K.
臺大學術典藏 2021-07-07T05:13:08Z Improved enamine-type addition of dehydroaporphine using microwave irradiation Huang W.-J.; Huang C.-C.; LING-WEI HSIN; Tsai Y.-M.; Lin C.-T.; Lin J.-H.; Lee S.-S.
臺大學術典藏 2021-07-07T05:13:07Z Activation of serotonin 5-HT7 receptor induces coronary flow increase in isolated rat heart Chang Chien C.-C.; LING-WEI HSIN; Su M.-J.
臺大學術典藏 2021-07-07T05:13:07Z Quinazolin-4-one derivatives as selective histone deacetylase-6 inhibitors for the treatment of Alzheimer's disease Yu C.-W.; Chang P.-T.; LING-WEI HSIN; Chern J.-W.
臺大學術典藏 2021-07-07T05:13:06Z A Novel potential positron emission tomography imaging agent for vesicular monoamine transporter type 2 Huang Z.-R.;Tsai C.-L.;Huang Y.-Y.;Shiue C.-Y.;Tzen K.-Y.;Yen R.-F.;Ling-Wei Hsin; Huang Z.-R.; Tsai C.-L.; Huang Y.-Y.; Shiue C.-Y.; Tzen K.-Y.; Yen R.-F.; LING-WEI HSIN
臺大學術典藏 2021-07-07T05:13:06Z Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain Freyberg Z.;Sonders M.S.;Aguilar J.I.;Hiranita T.;Karam C.S.;Flores J.;Pizzo A.B.;Zhang Y.;Farino Z.J.;Chen A.;Martin C.A.;Kopajtic T.A.;Fei H.;Hu G.;Lin Y.-Y.;Mosharov E.V.;Mccabe B.D.;Freyberg R.;Wimalasena K.;Ling-Wei Hsin;Sames D.;Krantz D.E.;Katz J.L.;Sulzer D.;Javitch J.A.; Freyberg Z.; Sonders M.S.; Aguilar J.I.; Hiranita T.; Karam C.S.; Flores J.; Pizzo A.B.; Zhang Y.; Farino Z.J.; Chen A.; Martin C.A.; Kopajtic T.A.; Fei H.; Hu G.; Lin Y.-Y.; Mosharov E.V.; McCabe B.D.; Freyberg R.; Wimalasena K.; LING-WEI HSIN; Sames D.; Krantz D.E.; Katz J.L.; Sulzer D.; Javitch J.A.
臺大學術典藏 2021-07-07T05:13:06Z Topoisomerase II inhibition suppresses the proliferation of telomerase-negative cancers Hsieh M.-H.; Tsai C.-H.; Lin C.-C.; Li T.-K.; Hung T.-W.; Chang L.-T.; LING-WEI HSIN; Teng S.-C.
臺大學術典藏 2021-07-07T05:13:05Z Targeting breast cancer stem cells by novel HDAC3-selective inhibitors Hsieh H.-Y.; Chuang H.-C.; Shen F.-H.; Detroja K.; LING-WEI HSIN; Chen C.-S.
臺大學術典藏 2021-07-07T05:13:05Z Fast and Facile Synthesis of 4-Nitrophenyl 2-Azidoethylcarbamate Derivatives from N-Fmoc-Protected α-Amino Acids as Activated Building Blocks for Urea Moiety-Containing Compound Library Chen Y.-Y.; Chang L.-T.; Chen H.-W.; Yang C.-Y.; LING-WEI HSIN
臺大學術典藏 2021-07-07T05:13:04Z Prospective comparison of (4S)-4-(3- 18 F-fluoropropyl)-l-glutamate versus 18 F-fluorodeoxyglucose PET/CT for detecting metastases from pancreatic ductal adenocarcinoma: a proof-of-concept study Cheng M.-F.;Huang Y.-Y.;Ho B.-Y.;Kuo T.-C.;Ling-Wei Hsin;Shiue C.-Y.;Kuo H.-C.;Jeng Y.-M.;Yen R.-F.;Tien Y.-W.; Cheng M.-F.; Huang Y.-Y.; Ho B.-Y.; Kuo T.-C.; LING-WEI HSIN; Shiue C.-Y.; Kuo H.-C.; Jeng Y.-M.; Yen R.-F.; Tien Y.-W.
臺大學術典藏 2021-07-07T05:13:04Z Identification of Buctopamine and Mebuctopamine, a β2 Receptor Agonist and Its Metabolite, in Swine Hair and Feed Additives Chen Y.-H.; Yang C.-Y.; Cheng C.W.; Lin Y.-Y.; Kuo S.L.; LING-WEI HSIN
臺大學術典藏 2021-07-07T05:13:04Z High-selective HDAC6 inhibitor promotes HDAC6 degradation following autophagy modulation and enhanced antitumor immunity in glioblastoma Liu J.-R.;Yu C.-W.;Hung P.-Y.;Ling-Wei Hsin;Chern J.-W.; Liu J.-R.; Yu C.-W.; Hung P.-Y.; LING-WEI HSIN; Chern J.-W.
臺大學術典藏 2021-07-07T05:13:03Z A novel isoquinoline derivative exhibits anti-inflammatory properties and improves the outcomes of endotoxemia Lee S.-Y.;Ling-Wei Hsin;Su M.-J.;Changchien C.-C.;Ku H.-C.; Lee S.-Y.; LING-WEI HSIN; Su M.-J.; ChangChien C.-C.; Ku H.-C.
臺大學術典藏 2021-07-07T05:13:03Z An one-pot two-step automated synthesis of [18F]T807 injection, its biodistribution in mice and monkeys, and a preliminary study in humans Huang Y.-Y.;Chiu M.-J.;Yen R.-F.;Tsai C.-L.;Hsieh H.-Y.;Chiu C.-H.;Wu C.-H.;Ling-Wei Hsin;Tzen K.-Y.;Cheng C.-Y.;Ma K.-H.;Shiue C.-Y.; Huang Y.-Y.; Chiu M.-J.; Yen R.-F.; Tsai C.-L.; Hsieh H.-Y.; Chiu C.-H.; Wu C.-H.; LING-WEI HSIN; Tzen K.-Y.; Cheng C.-Y.; Ma K.-H.; Shiue C.-Y.
臺大學術典藏 2021-07-07T05:13:02Z Synthesis and analysis of 4-(3-fluoropropyl)-glutamic acid stereoisomers to determine the stereochemical purity of (4S)-4-(3-[18F]fluoropropyl)-L-glutamic acid ([18F]FSPG) for clinical use Shih K.-T.; Huang Y.-Y.; Yang C.-Y.; Cheng M.-F.; Tien Y.-W.; Shiue C.-Y.; Yen R.-F.; LING-WEI HSIN
臺大學術典藏 2021-07-07T05:13:02Z Synthesis and evaluation of 2-(2′-((dimethylamino)methyl)-4′-(2-fluoroethoxy-substituted)phenylthio)benzenamine derivatives as potential positron emission tomography imaging agents for serotonin transporters Huang Y.-Y.; Chang L.-T.; Shen H.-Y.; Chen Y.-H.; Tzen K.-Y.; Shiue C.-Y.; LING-WEI HSIN
臺大學術典藏 2021-07-07T05:13:01Z Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity Peng C.; Li Y.-H.; Yu C.-W.; Cheng Z.-H.; Liu J.-R.; Hsu J.-L.; LING-WEI HSIN; Huang C.-T.; Juan H.-F.; Chern J.-W.; Cheng Y.-S.
臺大學術典藏 2021-07-07T05:13:00Z Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors Hsu K.-C.; Chu J.-C.; Tseng H.-J.; Liu C.-I.; Wang H.-C.; Lin T.E.; Lee H.-S.; LING-WEI HSIN; Wang A.H.-J.; Lin C.-H.; Huang W.-J.
臺大學術典藏 2021-05-21T11:40:45Z Synthesis and biological evaluation of phenothiazine derivative-containing hydroxamic acids as potent class II histone deacetylase inhibitors Hsu, Kai Cheng; Chu, Jung Chun; Tseng, Hui Ju; Liu, Chia I.; Wang, Hao Ching; Lin, Tony Eight; Lee, Hong Sheng; LING-WEI HSIN; Wang, Andrew H.J.; Lin, Chien Huang; Huang, Wei Jan
臺大學術典藏 2021-04-21T23:29:40Z Inhibitor development of MTH1 via high-throughput screening with fragment based library and MTH1 substrate binding cavity Peng, Cheng; Li, Yu Hsuan; CHAO-WU YU; Cheng, Ze Hua; Liu, Jia Rong; Hsu, Jui Ling; LING-WEI HSIN; Huang, Chen Tsung; HSUEH-FEN JUAN; JI-WANG CHERN; YI-SHENG CHENG
臺大學術典藏 2021-01-18T09:11:54Z Synthesis and analysis of 4-(3-fluoropropyl)-glutamic acid stereoisomers to determine the stereochemical purity of (4S)-4-(3-[18F]fluoropropyl)-L-glutamic acid ([18F]FSPG) for clinical use Shih, Kai Ting; YA-YAO HUANG; Yang, Chia Ying; MEI-FANG CHENG; YU-WEN TIEN; Shiue, Chyng Yann; Yen, Rouh Fang; LING-WEI HSIN
臺大學術典藏 2018-09-10T07:20:53Z Oxygenated analogues of 1-[2-(diphenylmethoxy)ethyl]- and 1- [2- [bis (4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents Lewis, D.B.;Matecka, D.;Zhang, Y.;Hsin, L.-W.;Dersch, C.M.;Stafford, D.;Glowa, J.R.;Rothman, R.B.;Rice, K.C.; LING-WEI HSIN
臺大學術典藏 2018-09-10T06:55:29Z Synthesis, DNA binding, and cytotoxicity of 1,4-bis(2-amino-ethylamino)anthraquinone-amino acid conjugates Hsin, L.-W.;Wang, H.-P.;Kao, P.-H.;Lee, O.;Chen, W.-R.;Chen, H.-W.;Guh, J.-H.;Chan, Y.-L.;His, C.-P.;Yang, M.-S.;Li, T.-K.;Lee, C.-H.; LING-WEI HSIN; JIH-HWA GUH; TSAI-KUN LI

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