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Institution Date Title Author
臺大學術典藏 2021-07-15T05:32:14Z A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo Wu, Yi Wen; Chao, Min Wu; Tu, Huang Ju; Chen, Liang Chieh; Hsu, Kai Cheng; Liou, Jing Ping; CHIA-RON YANG; Yen, Shih Chung; HuangFu, Wei Chun; Pan, Shiow Lin
臺大學術典藏 2020-05-28T06:37:09Z The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells Tu, Huang-Ju; Lin, Yi-Jyun; Chao, Min-Wu; Sung, Ting-Yi; Wu, Yi-Wen; Chen, Yi-Ying; Lin, Mei-Hsiang; Liou, Jing-Ping; Pan, Shiow-Lin; CHIA-RON YANG
臺大學術典藏 2020-05-28T06:30:47Z MPT0G413, A Novel HDAC6-Selective Inhibitor, and Bortezomib Synergistically Exert Anti-tumor Activity in Multiple Myeloma Cells Huang, Fang-I;Wu, Yi-Wen;Sung, Ting-Yi;Liou, Jing-Ping;Lin, Mei-Hsiang;Pan, Shiow-Lin;Chia-Ron Yang; Huang, Fang-I; Wu, Yi-Wen; Sung, Ting-Yi; Liou, Jing-Ping; Lin, Mei-Hsiang; Pan, Shiow-Lin; CHIA-RON YANG
臺大學術典藏 2020-05-28T06:28:07Z The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells Tu, Huang-Ju; Lin, Yi-Jyun; Chao, Min-Wu; Sung, Ting-Yi; Wu, Yi-Wen; Chen, Yi-Ying; Lin, Mei-Hsiang; Liou, Jing-Ping; Pan, Shiow-Lin; CHIA-RON YANG
臺大學術典藏 2020-05-28T06:26:17Z Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo Hsieh, Yi-Ling;Tu, Huang-Ju;Pan, Shiow-Lin;Liou, Jing-Ping;Chia-Ron Yang; Hsieh, Yi-Ling; Tu, Huang-Ju; Pan, Shiow-Lin; Liou, Jing-Ping; CHIA-RON YANG
臺大學術典藏 2018 5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes Lee, Hsueh-Yun; Fan, Sheng-Jun; Huang, Fang-I; Chao, Hsin-Yi; Hsu, Kai-Cheng; Lin, Tony Eight; Yeh, Teng-Kuang; Lai, Mei-Jung; Li, Yu-Hsuan; Huang, Hsiang-Ling; CHIA-RON YANG; Liou, Jing-Ping
衛生福利部國家中醫藥研究所 2017 Identification of 7-(4'-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cells. Wu, Tung-Yun;Cho, Ting-Yu;Lu, Chung-Kuang;Liou, Jing-Ping;Chen, Mei-Chuan
國立成功大學 2016-09 A novel tubulin polymerization inhibitor, MPT0B206, downregulates Bcr-Abl expression and induces apoptosis in imatinib-sensitive and imatinib-resistant CML cells Chen, Chih-Wei;Lee, Yueh-Lun;Liou, Jing-Ping;Liu, Yu-Hsiu;Liu, Chin-Wei;Chen, Tsai-Yun;Huang, Huei-Mei
國立成功大學 2016-07-01 MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma Peng, Hsuan-Yu; Cheng, Yun-Ching; Hsu, Yuan-Ming; Wu, Guan-Hsun; Kuo, Ching-Chuan; Liou, Jing-Ping; Chang, Jang-Yang; Jin, Shiow-Lian Catherine; Shiah, Shine-Gwo
國立臺灣大學 2016 Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma Chen, Mei-Chuan; Huang, Hui-Hsuan; Lai, Chin-Yu; Lin, Yi-Jyun; Liou, Jing-Ping; Lai, Mei-Jung; Li, Yu-Hsuan; Teng, Che-Ming; Yang, Chia-Ron; 楊家榮; 鄧哲明
國立臺灣大學 2016 LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo Huang, Han-Li; Chao, Min-Wu; Chen, Chung-Chun; Cheng, Chun-Chun; Chen, Mei-Chuan; Lin, Chao-Feng; Liou, Jing-Ping; Teng, Che-Ming; Pan, Shiow-Lin; 鄧哲明; 陳青周
國立臺灣大學 2016 MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer Huang, Han-Li; Chao, Min-Wu; Li, Ya-Chi; Chang, Li-Hsun; Chen, Chun-Han; Chen, Mei-Chuan; Cheng, Chun-Chun; Liou, Jing-Ping; Teng, Che-Ming; Pan, Shiow-Lin; 鄧哲明
國立臺灣大學 2016 2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase Lee, Hsueh-Yun; Chang, Chih-Yi; Su, Chih-Jou; Huang, Han-Li; Mehndiratta, Samir; Chao, Yuh-Hsuan; Hsu, Chia-Ming; Kumar, Sunil; Sung, Ting-Yi; Huang, Yi-Zhen; Li, Yu-Hsuan; Yang, Chia-Ron; Liou, Jing-Ping; 楊家榮
國立成功大學 2015-08-01 Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes Lee, Hsueh-Yun; Chang, Chih-Yi; Lai, Mei-Jung; Chuang, Hsun-Yueh; Kuo, Ching-Chuan; Chang, Chi-Yen; Chang, Jang-Yang; Liou, Jing-Ping
衛生福利部國家中醫藥研究所 2015 MT-4 suppresses resistant ovarian cancer growth through targeting tubulin and HSP27 Pai, Hui Chen; Kumar, Sunil; Shen, Chien-Chang; Liou, Jing Ping; Pan, Shiow Lin; Teng, Che Ming
國立臺灣大學 2015 Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo Huang, Han-Li; Peng, Chieh-Yu; Lai, Mei-Jung; Chen, Chun-Han; Lee, Hsueh-Yun; Wang, Jing-Chi; Liou, Jing-Ping; Pan, Shiow-Lin; Teng, Che-Ming; 鄧哲明
國立臺灣大學 2015 MT-4 Suppresses Resistant Ovarian Cancer Growth through Targeting Tubulin and HSP27 Pai, Hui Chen; Kumar, Sunil; Shen, Chien Chang; Liou, Jing Ping; Pan, Shiow Lin; Teng, Che Ming; 鄧哲明
國立臺灣大學 2015 The synergic effect of vincristine and vorinostat in leukemia in vitro and in vivo Chao, Min-Wu; Lai, Mei-Jung; Liou, Jing-Ping; Chang, Ya-Ling; Wang, Jing-Chi; Pan, Shiow-Lin; Teng, Che-Ming; 張雅玲; 鄧哲明
國立臺灣大學 2015 N-Sulfonyl-aminobiaryls as Antitubulin Agents and Inhibitors of Signal Transducers and Activators of Transcription 3 (STAT3) Signaling Lai, Mei-Jung; Lee, Hsueh-Yun; Chuang, Hsun-Yueh; Chang, Li-Hsun; Tsai, An-Chi; Chen, Mei-Chuan; Huang, Han-Lin; Wu, Yi-Wen; Teng, Che-Ming; Pan, Shiow-Lin; Liu, Yi-Min; Mehndiratta, Samir; Liou, Jing-Ping; 鄧哲明
國立臺灣大學 2015 Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin- 6-yl)acrylamide in human colorectal cancer cells in vitro and in vivo Chen, Chun-Han; Lee, Chia-Hwa; Liou, Jing-Ping; Teng, Che-Ming; Pan, Shiow-Lin; 鄧哲明
國立臺灣大學 2015 Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis Huang, Yen-Chia; Huang, Fang-I; Mehndiratta, Samir; Lai, Ssu-Chia; Liou, Jing-Ping; Yang, Chia-Ron; 楊家榮
國立成功大學 2014-09-01 Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents Mehndiratta, Samir; Chiang, Yi-Fang; Lai, Mei-Jung; Lee, Hsueh-Yun; Chen, Mei-Chuan; Kuo, Ching-Chuan; Chang, Chi-Yen; Chang, Jang-Yang; Liou, Jing-Ping
國立成功大學 2014-05-22 Azaindolylsulfonamides, with a More Selective Inhibitory Effect on Histone Deacetylase 6 Activity, Exhibit Antitumor Activity in Colorectal Cancer HCT116 Cells Lee, Hsueh-Yun; Tsai, An-Chi; Chen, Mei-Chuan; Shen, Po-Jung; Cheng, Yun-Ching; Kuo, Ching-Chuan; Pan, Shiow-Lin; Liu, Yi-Min; Liu, Jin-Fen; Yeh, Teng-Kuang; Wang, Jing-Chi; Chang, Chi-Yen; Chang, Jang-Yang; Liou, Jing-Ping
國立成功大學 2014-04 Antimitotic and vascular disrupting agents: 2-Hydroxy-3,4,5-trimethoxybenzophenones Chang, Chih-Yi; Chuang, Hsun-Yueh; Lee, Hsueh-Yun; Yeh, Teng-Kuang; Kuo, Ching-Chuan; Chang, Chi-Yen; Chang, Jang-Yang; Liou, Jing-Ping
臺北醫學大學 2014 Curcumin Suppress Cardiac Fibroblasts Activities by Regulating Proliferation, Migration, and the Extracellular Matrix Chung, Cheng-Chih;Kao, Yu-Hsun;Liou, Jing-Ping;Chen, Yi-Jen
臺北醫學大學 2014 Androgen attenuates cardiac fibroblasts activations through modulations of transforming growth factor-beta and angiotensin II signaling Chung, Cheng-Chih;Hsu, Rung-Chieh;Kao, Yu-Hsun;Liou, Jing-Ping;Lu, Yen-Yu;Chen, Yi-Jen
臺北醫學大學 2014 Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity Mehndiratta, Samir;Hsieh, Yi-Ling;Liu, Yi-Min;Wang, Amber Weiching;Lee, Hsueh-Yun;Liang, Lung-Yu;Kumar, Sunil;Teng, Che-Ming;Yang, Chia-Ron;Liou, Jing-Ping
臺北醫學大學 2014 Denbinobin upregulates miR-146a expression and attenuates IL-1 beta-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes Yang, Chia-Ron;Shih, Kao-Shang;Liou, Jing-Ping;Wu, Yi-Wen;Hsieh, I-Ni;Lee, Hsueh-Yun;Lin, Tzu-Cheng;Wang, Jyh-Horng
臺北醫學大學 2014 Antimitotic and vascular disrupting agents: 2-Hydroxy-3,4,5-trimethoxybenzophenones Chang, Chih-Yi;Chuang, Hsun-Yueh;Lee, Hsueh-Yun;Yeh, Teng-Kuang;Kuo, Ching-Chuan;Chang, Chi-Yen;Chang, Jang-Yang;Liou, Jing-Ping
臺北醫學大學 2014 Intermediary Metabolite Precursor Dimethyl-2-Ketoglutarate Stabilizes Hypoxia-Inducible Factor-1 alpha by Inhibiting Prolyl-4-Hydroxylase PHD2 Hou, Peifeng;Kuo, Ching-Ying;Cheng, Chun-Ting;Liou, Jing-Ping;Ann, David K.;Chen, Qiang
臺北醫學大學 2014 Tubulin inhibitors: a patent review Liu, Yi-Min;Chen, Hsiao-Ling;Lee, Hsueh-Yun;Liou, Jing-Ping
臺北醫學大學 2014 Effect of C7-substitution of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines on the selectivity towards a subclass of histone deacetylases Lee, Hsueh-Yun;Wang, Li-Ting;Li, Yu-Hsuan;Pan, Shiow-Lin;Chen, Yi-Lin;Teng, Che-Ming;Liou, Jing-Ping
臺北醫學大學 2014 In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells Tsai, An-Chi;Pai, Hui-Chen;Wang, Chih-Ya;Liou, Jing-Ping;Teng, Che-Ming;Wang, Jing-Chi;Pan, Shiow-Lin
臺北醫學大學 2014 A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKC delta and E-cadherin Wang, Li-Ting;Liou, Jing-Ping;Li, Yu-Hsuan;Liu, Yi-Min;Pan, Shiow-Lin;Teng, Che-Ming
國立臺灣大學 2014 Synergistic Interaction between the HDAC Inhibitor, MPT0E028, and Sorafenib in Liver Cancer Cells In Vitro and In Vivo Chen, Chun-Han; Chen, Mei-Chuan; Wang, Jing-Chi; Tsai, An-Chi; Chen, Ching-Shih; Liou, Jing-Ping; Pan, Shiow-Lin; Teng, Che-Ming; 鄧哲明
國立臺灣大學 2014 Effect of C7-substitution of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines on the selectivity towards a subclass of histone deacetylases Lee, Hsueh-Yun; Wang, Li-Ting; Li, Yu-Hsuan; Pan, Shiow-Lin; Chen, Yi-Lin; Teng, Che-Ming; Liou, Jing-Ping; 鄧哲明
國立臺灣大學 2014 In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells Tsai, An-Chi; Pai, Hui-Chen; Wang, Chih-Ya; Liou, Jing-Ping; Teng, Che-Ming; Wang, Jing-Chi; Pan, Shiow-Lin; 鄧哲明
國立臺灣大學 2014 Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity Mehndiratta, Samir; Hsieh, Yi-Ling; Liu, Yi-Min; Wang, Amber Weiching; Lee, Hsueh-Yun; Liang, Lung-Yu; Kumar, Sunil; Teng, Che-Ming; Yang, Chia-Ron; Liou, Jing-Ping; 楊家榮; 鄧哲明
國立臺灣大學 2014 A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKC delta and E-cadherin Wang, Li-Ting; Liou, Jing-Ping; Li, Yu-Hsuan; Liu, Yi-Min; Pan, Shiow-Lin; Teng, Che-Ming; 鄧哲明
國立臺灣大學 2014 A novel action mechanism for MPT0G013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through up-regulation of TIMP3 expression Wang, Chih-Ya; Liou, Jing-Ping; Tsai, An-Chi; Lai, Mei-Jung; Liu, Yi-Min; Lee, Hsueh-Yun; Wang, Jing-Chi; Pan, Shiow-Lin; Teng, Che-Ming; 鄧哲明
國立臺灣大學 2014 Denbinobin upregulates miR-146a expression and attenuates IL-1 beta-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes Yang, Chia-Ron; Shih, Kao-Shang; Liou, Jing-Ping; Wu, Yi-Wen; Hsieh, I-Ni; Lee, Hsueh-Yun; Lin, Tzu-Cheng; Wang, Jyh-Horng; 楊家榮; 王至弘
國立成功大學 2013-10-24 Furanylazaindoles: Potent Anticancer Agents in Vitro and in Vivo Lee, Hsueh-Yun; Pan, Shiow-Lin; Su, Min-Chieh; Liu, Yi-Min; Kuo, Ching-Chuan; Chang, Yi-Ting; Wu, Jian-Sung; Nien, Chih-Ying; Mehndiratta, Samir; Chang, Chi-Yen; Wu, Su-Ying; Lai, Mei-Jung; Chang, Jang-Yang; Liou, Jing-Ping
國立成功大學 2013-07 MPT0B098, a Novel Microtubule Inhibitor That Destabilizes the Hypoxia-Inducible Factor-1 alpha mRNA through Decreasing Nuclear-Cytoplasmic Translocation of RNA-Binding Protein HuR Cheng, Yun-Ching; Liou, Jing-Ping; Kuo, Ching-Chuan; Lai, Wen-Yang; Shih, Kuang-Hsing; Chang, Chi-Yen; Pan, Wen-Yu; Tseng, Joseph T.; Chang, Jang-Yang
國立成功大學 2013-03-12 A Novel Synthetic Microtubule Inhibitor, MPT0B214 Exhibits Antitumor Activity in Human Tumor Cells through Mitochondria-Dependent Intrinsic Pathway Chiang, Nai-Jung; Lin, Ching-I; Liou, Jing-Ping; Kuo, Ching-Chuan; Chang, Chi-Yen; Chen, Li-Tzong; Chang, Jang-Yang
國立成功大學 2013-02 Azatyrosinamides: Novel RAS-related Anticancer Agents Wang, Chun-Li; Lee, On; Huang, Chiu-Fen; Li, Eric I-Chian; Teng, Che-Ming; Pan, Shiow-Lin; Lian, Jang-Feng; Chang, Feng-Shou; Liou, Jing-Ping; Wang, Hui-Po
臺北醫學大學 2012 Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolinest Lee, Hsueh-Yun;Lee, lin-Wen;Nien, Chih-Ying;Kuo, Ching-Chuan;Lin, Pen-Yuan;Chang, Chi-Yen;Chang, Jang-Yang;Liou, Jing-Ping
臺北醫學大學 2012 Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolinest Lee, Hsueh-Yun;Lee, lin-Wen;Nien, Chih-Ying;Kuo, Ching-Chuan;Lin, Pen-Yuan;Chang, Chi-Yen;Chang, Jang-Yang;Liou, Jing-Ping
國立成功大學 2012 Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines Lee, Hsueh-Yun; Lee, Lin-Wen; Nien, Chih-Ying; Kuo, Ching-Chuan; Lin, Pen-Yuan; Chang, Chi-Yen; Chang, Jang-Yang; Liou, Jing-Ping
國立成功大學 2011-03-07 2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors Chuang, Hsun-Yueh; Chang, Jang-Yang; Lai, Mei-Jung; Kuo, Ching-Chuan; Lee, Hsueh-Yun; Hsieh, Hsing-Pang; Chen, Ying-Jen; Chen, Li-Tzong; Pan, Wen-Yu; Liou, Jing-Ping
國立成功大學 2011 Concise syntheses of N-aryl-5,6,7-trimethoxyindoles as antimitotic and vascular disrupting agents: application of the copper-mediated Ullmann-type arylation Lee, Hsueh-Yun; Chang, Jang-Yang; Chang, Ling-Yin; Lai, Wen-Yang; Lai, Mei-Jung; Shih, Kuang-Hsing; Kuo, Ching-Chuan; Chang, Chi-Yen; Liou, Jing-Ping

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