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Showing items 1-50 of 136 (3 Page(s) Totally)
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| 國家衛生研究院 |
2025-07-14 |
Contribution of prostaglandin E2-induced neuronal excitation to drug resistance in glioblastoma countered by a novel blood-brain barrier crossing celecoxib derivative
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Shen, CJ;Chen, HC;Lin, CL;Thakur, A;Onuku, R;Chen, IC;Li, HY;Chang, KY;Chuang, JY;Yang, WB;Lin, HY;Shen, YR;Liou, JP;Chang, WC;Hsu, TI |
| 國家衛生研究院 |
2025-02 |
Development of BACE2-IN-1/tranylcypromine-based compounds to induce steroidogenesis-dependent neuroprotection
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Banerjee, S;Hsu, YT;Nguyen, DH;Yeh, SH;Liou, KC;Liu, JJ;Liou, JP;Chuang, JY |
| 國家衛生研究院 |
2025-01-21 |
Repurposing linezolid in conjunction with histone deacetylase inhibitor access in the realm of glioblastoma therapies
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Chen, IC;Lin, HY;Liu, ZY;Cheng, WJ;Yeh, TY;Yang, WB;Tran, HY;Lai, MJ;Wang, CH;Kao, TY;Hung, CY;Huang, YL;Liou, KC;Hsieh, CM;Hsu, T;Liou, JP |
| 國家衛生研究院 |
2024-04-01 |
Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress
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Sharma, R;Chiang, YH;Chen, HC;Lin, HY;Yang, WB;Nepali, K;Lai, MJ;Chen, KY;Liou, JP;Hsu, TI |
| 國家衛生研究院 |
2024-01-29 |
First-in-class dual EZH2-HSP90 inhibitor eliciting striking antiglioblastoma activity in vitro and in vivo
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Sharma, S;Wang, SA;Yang, WB;Lin, HY;Lai, MJ;Chen, HC;Kao, TY;Hsu, FL;Nepali, K;Hsu, TI;Liou, JP |
| 國家衛生研究院 |
2023-08 |
Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4-isopropylresorcinol for glioblastoma
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Tseng, HJ;Banerjee, S;Qian, B;Lai, MJ;Wu, TY;Hsu, TI;Lin, TE;Hsu, KC;Chuang, KH;Liou, JP;Shih, JC |
| 國家衛生研究院 |
2023-07-22 |
The complex role of eicosanoids in the brain: Implications for brain tumor development and therapeutic opportunities
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Chen, HC;Chang, WC;Chuang, JY;Chang, KY;Liou, JP;Hsu, TI |
| 國家衛生研究院 |
2022-12-05 |
2,6-Difluorobenzamide derivatives as store-operated calcium channel (SOC) inhibitors
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Wang, YS;Yeh, TK;Chang, WC;Liou, JP;Liu, YM;Huang, WC |
| 國家衛生研究院 |
2022-02-02 |
HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells
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Wu, AC;Yang, WB;Chang, KY;Lee, JS;Liou, JP;Su, RY;Cheng, SM;Hwang, DY;Kikkawa, U;Hsu, TI;Wang, CY;Chang, WC;Chen, PY;Chuang, JY |
| 國家衛生研究院 |
2021-09-28 |
Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells
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Yang, WB;Wu, AC;Hsu, TI;Liou, JP;Lo, WL;Chang, KY;Chen, PY;Kikkawa, U;Yang, ST;Kao, TJ;Chen, RM;Chang, WC;Ko, CY;Chuang, JY |
| 國家衛生研究院 |
2021-09 |
Suppression of extracellular vesicle VEGF-C-mediated lymphangiogenesis and pancreatic cancer early dissemination by a selective HDAC1/2 inhibitor
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Wang, CA;Li, CF;Huang, RC;Li, YH;Liou, JP;Tsai, SJ |
| 國家衛生研究院 |
2020-04-24 |
Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma
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Yang, WB;Hsu, CC;Hsu, TI;Liou, JP;Chang, KY;Chen, PY;Liu, JJ;Yang, ST;Wang, JY;Yeh, SH;Chen, RM;Chang, WC;Chuang, JY |
| 國家衛生研究院 |
2020-02-01 |
Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment
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Kaur, N;Fang, YC;Lee, HY;Singh, A;Nepali, K;Lin, MH;Yeh, TK;Lai, MJ;Chan, L;Tu, YK;Banerjee, S;Hu, CJ;Liou, JP |
| 國家衛生研究院 |
2019-02-21 |
Synthesis and evaluation of novel 7H-pyrrolo-[2,3-d]pyrimidine derivatives as potential anticancer agents
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Liu, YM;Chen, CH;Yeh, TK;Liou, JP |
| 國家衛生研究院 |
2019-01-15 |
1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase
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Lai, MJ;Ojha, R;Lin, MH;Liu, YM;Lee, HY;Lin, TE;Hsu, KC;Chang, CY;Chen, MC;Nepali, K;Chang, JY;Liou, JP |
| 國家衛生研究院 |
2018-08-23 |
5-aroylindoles act as selective histone deacetylase 6 inhibitors ameliorating alzheimer's disease phenotypes
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Lee, HY;Fan, SJ;Huang, FI;Chao, HY;Hsu, KC;Lin, TE;Yeh, TK;Lai, MJ;Li, YH;Huang, HL;Yang, CR;Liou, JP |
| 國家衛生研究院 |
2018-08-04 |
Upregulation of Znf179 acetylation by SAHA protects cells against oxidative stress
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Wu, CC;Lee, PT;Kao, TJ;Chou, SY;Su, RY;Lee, YC;Yeh, SH;Liou, JP;Hsu, TI;Su, TP;Chuang, CK;Chang, WC;Chuang, JY |
| 國家衛生研究院 |
2018-06-15 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition [Erratum: Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.]
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Nepali, K;Kumar, S;Huang, HL;Kuo, FC;Lee, CH;Kuo, CC;Yeh, TK;Li, YH;Chang, JY;Liou, JP;Lee, HY |
| 國家衛生研究院 |
2018-03-28 |
Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma
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Tsai, IT;Kuo, CC;Liou, JP;Chang, JY |
| 國家衛生研究院 |
2017-08-12 |
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase
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Chang, KY;Hsu, TI;Hsu, CC;Tsai, SY;Liu, JJ;Chou, SW;Liu, MS;Liou, JP;Ko, CY;Chen, KY;Hung, JJ;Chang, WC;Chuang, CK;Kao, TJ;Chuang, JY |
| 國家衛生研究院 |
2017-08 |
Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness
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Hou, PC;Li, YH;Lin, SC;Lin, SC;Lee, JC;Lin, BW;Liou, JP;Chang, JY;Kuo, CC;Liu, YM;Sun, HS;Tsai, SJ |
| 國家衛生研究院 |
2016-11-18 |
Suberoylanilide hydroxamic acid represses glioma stem-like cells
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Hsu, CC;Chang, WC;Hsu, TI;Liu, JJ;Yeh, SH;Wang, JY;Liou, JP;Ko, CY;Chang, KY;Chuang, JY |
| 國家衛生研究院 |
2016-07-01 |
MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma
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Peng, HY;Cheng, YC;Hsu, YM;Wu, GH;Kuo, CC;Liou, JP;Chang, JY;Jin, SC;Shiah, SG |
| 國家衛生研究院 |
2016-01 |
2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition
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Nepali, K;Kumar, S;Huang, HL;Kuo, FC;Lee, CH;Kuo, CC;Yeh, TK;Li, YH;Chang, JY;Liou, JP;Lee, HY |
| 國家衛生研究院 |
2015-08 |
Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes
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Lee, HY;Chang, CY;Lai, MJ;Chuang, HY;Kuo, CC;Chang, CY;Chang, JY;Liou, JP |
| 國家衛生研究院 |
2015-01 |
1-Arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells
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Liu, YM;Lee, HY;Chen, CH;Lee, CH;Wang, LT;Pan, SL;Lai, MJ;Yeh, TK;Liou, JP |
| 臺北醫學大學 |
2015 |
MT-4 Suppresses Resistant Ovarian Cancer Growth through Targeting Tubulin and HSP27
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Pai, HC;Kumar, S;Shen, CC;Liou, JP;Pan, SL;Teng, CM |
| 臺北醫學大學 |
2015 |
Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo
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Huang, HL;Peng, CY;Lai, MJ;Chen, CH;Lee, HY;Wang, JC;Liou, JP;Pan, SL;Teng, CM. |
| 臺北醫學大學 |
2015 |
1-Arylsulfonyl-5-(N-hydroxyacrylamide)tetrahydroquinolines as potent histone deacetylase inhibitors suppressing the growth of prostate cancer cells
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Liu, YM;Lee, HY;Chen, CH;Lee, CH;Wang, LT;Pan, SL;Lai, MJ;Yeh, TK;Liou, JP. |
| 中國醫藥大學 |
2014-12 |
Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo.
|
(Huang HL);彭婕妤(Chieh-Yu Peng);(Lai MJ);(Chen CH);(Lee HY);(Wang JC);(Liou JP)*;(Pan SL)*;(Teng CM)* |
| 國家衛生研究院 |
2014-09 |
Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents
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Mehndiratta, S;Chiang, YF;Lai, MJ;Lee, HY;Chen, MC;Kuo, CC;Chang, CY;Chang, JY;Liou, JP |
| 國家衛生研究院 |
2014-05 |
Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells
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Lee, HY;Tsai, AC;Chen, MC;Shen, PJ;Cheng, YC;Kuo, CC;Pan, SL;Liu, YM;Liu, JF;Yeh, TK;Wang, JC;Chang, CY;Chang, JY;Liou, JP |
| 國家衛生研究院 |
2014-04 |
Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones
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Chang, CY;Chuang, HY;Lee, HY;Yeh, TK;Kuo, CC;Chang, CY;Chang, JY;Liou, JP |
| 國家衛生研究院 |
2014-04 |
Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib
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Tsai, AC;Wang, CY;Liou, JP;Pai, HC;Hsiao, CJ;Chang, JY;Wang, JC;Teng, CM;Pan, SL |
| 臺北醫學大學 |
2014 |
Azaindolylsulfonamides, with a More Selective Inhibitory Effect on Histone Deacetylase 6 Activity, Exhibit Antitumor Activity in Colorectal Cancer HCT116 Cells
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Lee, HY;Tsai, AC;Chen, MC;Shen, PJ;Cheng, YC;Kuo, CC;Pan, SL;Liu, YM;Liu, JF;Yeh, TK;Wang, JC;Chang, CY;Chang, JY;Liou, JP. |
| 臺北醫學大學 |
2014 |
Androgen attenuates cardiac fibroblasts activations through modulations of transforming growth factor-β and angiotensin II signaling
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Chung, CC;Hsu, RC;YH*, Kao;Liou, JP;Lu, YY;YJ*, Chen |
| 臺北醫學大學 |
2014 |
A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKCδ and E-cadherin
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Wang, LT;Liou, JP;Li, YH;Liu, YM;Pan, SL;Teng, CM |
| 臺北醫學大學 |
2014 |
Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones
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Chang, CY;Chuang, HY;Lee, HY;Yeh, TK;Kuo, CC;Chang, CY;Chang, JY;Liou, JP |
| 臺北醫學大學 |
2014 |
Indolyl or Indolinyl hydroxamate compounds
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Chen, CS;Liou, JP;Liu, HJ;Hung, KS;Shan, PW;Chiu, WT;Teng, CM |
| 臺北醫學大學 |
2014 |
Curcumin Suppress Cardiac Fibroblasts Activitiesby Regulating Proliferation, Migration, and the Extracellular Matrix
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Chung, CC;Kao, YH;Liou, JP;Chen, YJ |
| 臺北醫學大學 |
2014 |
Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes
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Yang, CR;Shih, KS;Liou, JP;Wu, YW;Hsieh, IN;Lee, HY;Lin, TC;Wang, JH |
| 臺北醫學大學 |
2014 |
In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells
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Tsai, AC;Pai, HC;Wang, CY;Liou, JP;Teng, CM;Wang, JC;Pan, SL |
| 臺北醫學大學 |
2014 |
Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity
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Mehndiratta, S;Hsieh, YL;Liu, YM;Wang, AW;Lee, HY;Liang, LY;Kumar, S;Teng, CM;CR*, Yang;Liou, JP*. |
| 臺北醫學大學 |
2014 |
Intermediary Metabolite Precursor Dimethyl-2-Ketoglutarate Stabilizes Hypoxia-Inducible Factor-1α by Inhibiting Prolyl-4-Hydroxylase PHD2
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Hou, P;Kuo, CY;Cheng, CT;Liou, JP;Ann, DK;Chen, Q |
| 臺北醫學大學 |
2014 |
K20E, an oxidative-coupling compound of methyl caffeate, exhibits anti-angiogenic activities through down-regulations of VEGF and VEGF receptor-2
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Lee, HY;Wang, LT;Li, YH;Pan, SL;Chen, YL;Teng, CM;Liou, JP |
| 臺北醫學大學 |
2014 |
Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib
|
Tsai, AC;Wang, CY;Liou, JP;Pai, HC;Hsiao, CJ;Chang, JY;Wang, JC;Teng, CM;Pan, SL. |
| 臺北醫學大學 |
2014 |
Preclinical anti-arthritic study and pharmacokinetic properties of a potent histone deacetylase inhibitor MPT0G009
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Hsieh, IN;Liou, JP;Lee, HY;Lai, MJ;Li, YH;Yang, CR |
| 臺北醫學大學 |
2014 |
Tubulin inhibitors: a patent review
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Liu, YM;Chen, HL;Lee, HY;Liou, JP |
| 臺北醫學大學 |
2014 |
A novel action mechanism for MPT0G013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through up-regulaiton of TIMP3 expression
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Wang, CY;Liou, JP;Tsai, AC;Lai, MJ;Liu, YM;Lee, HY;Wang, JC;SL*, Pan;CM*, Teng |
| 臺北醫學大學 |
2014 |
In vitro and in vivo antitumor effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells
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Tsai, AC;Pai, HC;Wang, CY;Liou, JP;Teng, CM;Wang, JC;Pan, SL |
Showing items 1-50 of 136 (3 Page(s) Totally)
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